EA202290048A1 - Лекарственное средство и его применение для лечения бактериальных инфекций, связанных с биопленкой - Google Patents

Лекарственное средство и его применение для лечения бактериальных инфекций, связанных с биопленкой

Info

Publication number
EA202290048A1
EA202290048A1 EA202290048A EA202290048A EA202290048A1 EA 202290048 A1 EA202290048 A1 EA 202290048A1 EA 202290048 A EA202290048 A EA 202290048A EA 202290048 A EA202290048 A EA 202290048A EA 202290048 A1 EA202290048 A1 EA 202290048A1
Authority
EA
Eurasian Patent Office
Prior art keywords
biofilm
bacterial infections
medicine
treatment
infections associated
Prior art date
Application number
EA202290048A
Other languages
English (en)
Inventor
Юстина Новаковска
Линда Кади
Грегуар Воньо
Original Assignee
Дебиофарм Интернэшнл C.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дебиофарм Интернэшнл C.A. filed Critical Дебиофарм Интернэшнл C.A.
Publication of EA202290048A1 publication Critical patent/EA202290048A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

Настоящее изобретение относится к применению Афабицина в способе лечения бактериальных инфекций, связанных с биопленкой, которая содержит стафилококковые бактерии, при этом способ включает введение пациенту Афабицина в комбинации с по меньшей мере одним дополнительным средством, выбранным из липопептидов, гликопептидов и линкозамидов, таких как Даптомицин и/или Ванкомицин.
EA202290048A 2019-06-14 2020-06-12 Лекарственное средство и его применение для лечения бактериальных инфекций, связанных с биопленкой EA202290048A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19180281 2019-06-14
PCT/EP2020/066305 WO2020249731A1 (en) 2019-06-14 2020-06-12 Afabicin for use for treating bacterial infections involving biofilm

Publications (1)

Publication Number Publication Date
EA202290048A1 true EA202290048A1 (ru) 2022-03-10

Family

ID=66867028

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202290048A EA202290048A1 (ru) 2019-06-14 2020-06-12 Лекарственное средство и его применение для лечения бактериальных инфекций, связанных с биопленкой

Country Status (15)

Country Link
US (1) US20230126947A1 (ru)
EP (1) EP3982975A1 (ru)
JP (1) JP7418475B2 (ru)
KR (1) KR20220020963A (ru)
CN (1) CN113939306A (ru)
AU (1) AU2020293635A1 (ru)
BR (1) BR112021025306A8 (ru)
CA (1) CA3139942A1 (ru)
CL (1) CL2021003317A1 (ru)
EA (1) EA202290048A1 (ru)
IL (1) IL288861A (ru)
MA (1) MA56184A (ru)
MX (1) MX2021015513A (ru)
SG (1) SG11202113174SA (ru)
WO (1) WO2020249731A1 (ru)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003673B2 (en) * 2005-05-31 2011-08-23 Cubist Pharmaceuticals, Inc. Daptomycin for the treatment of biofilm and catheter salvage
NZ702695A (en) 2012-06-19 2015-10-30 Debiopharm Int Sa Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
FR3017294B1 (fr) 2014-02-07 2021-10-01 Atlangram Nanoparticules lipidiques comprenant un antibiotique et leurs utilisations en therapie
US10751351B2 (en) * 2016-02-26 2020-08-25 Debiopharm International S.A. Medicament for treatment of diabetic foot infections

Also Published As

Publication number Publication date
KR20220020963A (ko) 2022-02-21
CL2021003317A1 (es) 2022-09-20
MX2021015513A (es) 2022-04-20
JP2022535598A (ja) 2022-08-09
MA56184A (fr) 2022-04-20
IL288861A (en) 2022-02-01
BR112021025306A8 (pt) 2022-09-20
US20230126947A1 (en) 2023-04-27
WO2020249731A1 (en) 2020-12-17
SG11202113174SA (en) 2021-12-30
EP3982975A1 (en) 2022-04-20
BR112021025306A2 (pt) 2022-02-01
AU2020293635A1 (en) 2022-01-27
CN113939306A (zh) 2022-01-14
JP7418475B2 (ja) 2024-01-19
CA3139942A1 (en) 2020-12-17

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