EA202191417A1 - Синтетические кишечные бактериальные сообщества с высокой степенью сложности - Google Patents

Синтетические кишечные бактериальные сообщества с высокой степенью сложности

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Publication number
EA202191417A1
EA202191417A1 EA202191417A EA202191417A EA202191417A1 EA 202191417 A1 EA202191417 A1 EA 202191417A1 EA 202191417 A EA202191417 A EA 202191417A EA 202191417 A EA202191417 A EA 202191417A EA 202191417 A1 EA202191417 A1 EA 202191417A1
Authority
EA
Eurasian Patent Office
Prior art keywords
high degree
complexity
intestinal bacterial
bacterial communities
synthetic intestinal
Prior art date
Application number
EA202191417A
Other languages
English (en)
Inventor
Майкл А. Фишбах
Эриел Р. Брамбо
Элис Г. Чэн
Дилан Додд
Джастин Л. Сонненбург
Кервин К. Хуан
Андрес Хесус Аранда-Диаз
Стив Хиггинботтом
Мин ВАН
Фэйцао Брайан Юй
Original Assignee
Чан Цукерберг Байохаб, Инк.
Борд Оф Трастиз Оф Дзе Лелэнд Стэнфорд Джуниор Юниверсити
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чан Цукерберг Байохаб, Инк., Борд Оф Трастиз Оф Дзе Лелэнд Стэнфорд Джуниор Юниверсити filed Critical Чан Цукерберг Байохаб, Инк.
Publication of EA202191417A1 publication Critical patent/EA202191417A1/ru

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретением обеспечиваются определенные кишечные микробные сообщества с высокой степенью сложности, способные к достижению существенного приживления и обладающие стабильностью после заражения микроорганизмами калового сообщества у человека, и способы их создания. Также обеспечиваются способы применения определенных кишечных микробных сообществ с высокой степенью сложности для лечения дисбактериоза или патологического состояния у животного.
EA202191417A 2018-11-21 2019-11-21 Синтетические кишечные бактериальные сообщества с высокой степенью сложности EA202191417A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862770706P 2018-11-21 2018-11-21
PCT/US2019/062689 WO2020106999A1 (en) 2018-11-21 2019-11-21 High-complexity synthetic gut bacterial communities

Publications (1)

Publication Number Publication Date
EA202191417A1 true EA202191417A1 (ru) 2021-10-08

Family

ID=70773670

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202191417A EA202191417A1 (ru) 2018-11-21 2019-11-21 Синтетические кишечные бактериальные сообщества с высокой степенью сложности

Country Status (10)

Country Link
US (1) US20220023354A1 (ru)
EP (1) EP3883384A4 (ru)
JP (1) JP2022513104A (ru)
CN (1) CN113474448A (ru)
AU (1) AU2019384187A1 (ru)
CA (1) CA3120569A1 (ru)
EA (1) EA202191417A1 (ru)
IL (1) IL283223A (ru)
SG (1) SG11202105284YA (ru)
WO (1) WO2020106999A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021237162A1 (en) * 2020-05-21 2021-11-25 Chan Zuckerberg Biohub, Inc. High-complexity synthetic gut bacterial communities
CN113509494A (zh) * 2021-09-06 2021-10-19 南京医科大学 普氏菌在制备治疗胆汁淤积性疾病的药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014232370B2 (en) * 2013-03-15 2018-11-01 Seres Therapeutics, Inc. Network-based microbial compositions and methods
WO2015003001A1 (en) * 2013-07-01 2015-01-08 The Washington University Methods for identifying supplements that increase gut colonization by an isolated bacterial species, and compositions derived therefrom
WO2018075886A1 (en) * 2016-10-21 2018-04-26 The University Of Chicago Compositions and methods for inducing immune system maintenance to prevent and/or treat infections
EP3559209A4 (en) * 2016-12-23 2021-03-10 Keio University COMPOSITION AND METHOD OF INDUCTION OF CD8 + CELLS
US11045501B2 (en) * 2017-01-19 2021-06-29 Bactaviva Ab Autologous fecal sample for use in the treatment of microbial dysbiosis

Also Published As

Publication number Publication date
EP3883384A4 (en) 2023-03-15
US20220023354A1 (en) 2022-01-27
CA3120569A1 (en) 2020-05-28
AU2019384187A1 (en) 2021-06-10
EP3883384A1 (en) 2021-09-29
CN113474448A (zh) 2021-10-01
WO2020106999A1 (en) 2020-05-28
JP2022513104A (ja) 2022-02-07
SG11202105284YA (en) 2021-06-29
IL283223A (en) 2021-06-30

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