EA202190185A1 - NEW COMPOSITIONS OF N-CARBAMOILMETHYL-4-PHENYL-2-PYRROLIDONE - Google Patents

NEW COMPOSITIONS OF N-CARBAMOILMETHYL-4-PHENYL-2-PYRROLIDONE

Info

Publication number
EA202190185A1
EA202190185A1 EA202190185A EA202190185A EA202190185A1 EA 202190185 A1 EA202190185 A1 EA 202190185A1 EA 202190185 A EA202190185 A EA 202190185A EA 202190185 A EA202190185 A EA 202190185A EA 202190185 A1 EA202190185 A1 EA 202190185A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pyrrolidone
phenyl
new compositions
carbamoilmethyl
phenylpyrrolidin
Prior art date
Application number
EA202190185A
Other languages
Russian (ru)
Inventor
Владимир Викторович НЕСТЕРУК
Original Assignee
Общество С Ограниченной Ответственностью "Валента-Интеллект"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Общество С Ограниченной Ответственностью "Валента-Интеллект" filed Critical Общество С Ограниченной Ответственностью "Валента-Интеллект"
Publication of EA202190185A1 publication Critical patent/EA202190185A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Предложены новые составы, содержащие N-карбамоилметил-4-фенил-2-пирролидон и по меньшей мере одно дополнительное соединение, выбранное из группы, включающей 4-фенилпирролидон-2, 2-(2-оксо-4-фенилпирролидин-1-ил)уксусную кислоту, этил-2-(2-оксо-4-фенилпирролидин-1-ил)ацетат и их оптические изомеры, менее гигроскопичные и более стабильные, чем известная субстанция фонтурацетама, а также фармацевтическая композиция на основе упомянутого состава и лекарственное средство на основе упомянутой фармацевтической композиции.New compositions are proposed containing N-carbamoylmethyl-4-phenyl-2-pyrrolidone and at least one additional compound selected from the group consisting of 4-phenylpyrrolidone-2, 2- (2-oxo-4-phenylpyrrolidin-1-yl) acetic acid, ethyl 2- (2-oxo-4-phenylpyrrolidin-1-yl) acetate and their optical isomers, which are less hygroscopic and more stable than the known substance fonturacetam, as well as a pharmaceutical composition based on the above composition and a drug based on said pharmaceutical composition.

EA202190185A 2018-07-04 2019-06-26 NEW COMPOSITIONS OF N-CARBAMOILMETHYL-4-PHENYL-2-PYRROLIDONE EA202190185A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2018124410A RU2699669C1 (en) 2018-07-04 2018-07-04 Novel compositions of n-carbamoylmethyl-4-phenyl-2-pyrrolidone
PCT/RU2019/050095 WO2020009616A1 (en) 2018-07-04 2019-06-26 Novel n-carbamoylmethyl-4-phenyl-2-pyrrolidone compositions

Publications (1)

Publication Number Publication Date
EA202190185A1 true EA202190185A1 (en) 2021-04-16

Family

ID=67851362

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202190185A EA202190185A1 (en) 2018-07-04 2019-06-26 NEW COMPOSITIONS OF N-CARBAMOILMETHYL-4-PHENYL-2-PYRROLIDONE

Country Status (3)

Country Link
EA (1) EA202190185A1 (en)
RU (1) RU2699669C1 (en)
WO (1) WO2020009616A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2732245C1 (en) * 2019-08-30 2020-09-14 Ооо "Валента-Интеллект" Novel compositions of n-carbamoylmethyl-4-phenyl-2-pyrrolidone for treating and preventing obesity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
RU2240783C1 (en) * 2003-07-17 2004-11-27 Открытое акционерное общество "Щелковский витаминный завод" Pharmaceutical composition eliciting nootropic activity and method for its preparing
RU2013141257A (en) * 2011-03-11 2015-04-20 Гриндекс 4R, 5R-ENANTIOMER 2- (5-METHYL-2-OXO-4-Phenylpyrrolidin-1-IL) ACETAMIDE WITH NOOTROPIC ACTIVITY
RU2539375C1 (en) * 2013-11-07 2015-01-20 Общество С Ограниченной Ответственностью "Валента-Интеллект" Tabletted pharmaceutical composition and method for producing it

Also Published As

Publication number Publication date
WO2020009616A1 (en) 2020-01-09
RU2699669C1 (en) 2019-09-09

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