EA202091989A1 - Способы лечения язвенного колита - Google Patents

Способы лечения язвенного колита

Info

Publication number
EA202091989A1
EA202091989A1 EA202091989A EA202091989A EA202091989A1 EA 202091989 A1 EA202091989 A1 EA 202091989A1 EA 202091989 A EA202091989 A EA 202091989A EA 202091989 A EA202091989 A EA 202091989A EA 202091989 A1 EA202091989 A1 EA 202091989A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
ulcer
methods
disease
invention generally
Prior art date
Application number
EA202091989A
Other languages
English (en)
Russian (ru)
Inventor
Джеймс Бенедикт Канаван
Стюарт Уильям Фридрих
Катрин Энн Крюгер
Кейтрин Мильх
Джей Лоуренс Таттл
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA202091989A1 publication Critical patent/EA202091989A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EA202091989A 2018-03-30 2019-03-28 Способы лечения язвенного колита EA202091989A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862650314P 2018-03-30 2018-03-30
PCT/US2019/024633 WO2019191464A1 (en) 2018-03-30 2019-03-28 Methods of treating ulcerative colitis

Publications (1)

Publication Number Publication Date
EA202091989A1 true EA202091989A1 (ru) 2021-01-13

Family

ID=66429483

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202091989A EA202091989A1 (ru) 2018-03-30 2019-03-28 Способы лечения язвенного колита

Country Status (29)

Country Link
US (2) US12152072B2 (cg-RX-API-DMAC10.html)
EP (3) EP4752157A2 (cg-RX-API-DMAC10.html)
JP (4) JP7119114B2 (cg-RX-API-DMAC10.html)
KR (1) KR102552693B1 (cg-RX-API-DMAC10.html)
CN (1) CN111936165A (cg-RX-API-DMAC10.html)
AU (3) AU2019243283C1 (cg-RX-API-DMAC10.html)
BR (1) BR112020018099A2 (cg-RX-API-DMAC10.html)
CA (1) CA3095297A1 (cg-RX-API-DMAC10.html)
DK (2) DK3773715T3 (cg-RX-API-DMAC10.html)
EA (1) EA202091989A1 (cg-RX-API-DMAC10.html)
ES (2) ES3063700T3 (cg-RX-API-DMAC10.html)
FI (2) FI4327866T3 (cg-RX-API-DMAC10.html)
HR (2) HRP20240904T1 (cg-RX-API-DMAC10.html)
HU (1) HUE067445T2 (cg-RX-API-DMAC10.html)
IL (2) IL312807B2 (cg-RX-API-DMAC10.html)
LT (2) LT3773715T (cg-RX-API-DMAC10.html)
MA (2) MA52216B1 (cg-RX-API-DMAC10.html)
MD (2) MD3773715T2 (cg-RX-API-DMAC10.html)
MX (1) MX2020010269A (cg-RX-API-DMAC10.html)
MY (1) MY202368A (cg-RX-API-DMAC10.html)
PL (2) PL4327866T3 (cg-RX-API-DMAC10.html)
PT (2) PT3773715T (cg-RX-API-DMAC10.html)
RS (2) RS65661B1 (cg-RX-API-DMAC10.html)
SG (1) SG11202009526RA (cg-RX-API-DMAC10.html)
SI (2) SI4327866T1 (cg-RX-API-DMAC10.html)
TW (2) TWI744617B (cg-RX-API-DMAC10.html)
UA (1) UA128578C2 (cg-RX-API-DMAC10.html)
WO (1) WO2019191464A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA202005388B (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3972690A4 (en) 2019-05-23 2023-07-05 Janssen Biotech, Inc. METHOD OF TREATMENT OF INFLAMMATORY BOWEL DISEASE USING COMBINATION THERAPY OF ANTIBODIES TO IL-23 AND TNF-ALPHA
IL295545A (en) * 2020-02-14 2022-10-01 Janssen Biotech Inc Safe and effective method of treating ulcerative colitis with anti-il-12/il23 antibody
CA3183927A1 (en) 2020-05-21 2021-11-25 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
JP7423815B2 (ja) * 2020-10-20 2024-01-29 セトラスホールディングス株式会社 治験管理装置、治験管理方法、治験管理プログラム及び治験管理システム
US20220259301A1 (en) * 2021-01-06 2022-08-18 Abbvie Inc. Methods of treating crohn's disease and ulcerative colitis
BR112023024064A2 (pt) * 2021-05-20 2024-01-30 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
WO2022251623A1 (en) * 2021-05-28 2022-12-01 Eli Lilly And Company Anti-il-23p19 antibody regulation of genes involved in ulcerative colitis
KR20240103043A (ko) * 2021-11-23 2024-07-03 얀센 바이오테크 인코포레이티드 항-il23 특이적 항체로 궤양성 결장염을 치료하는 방법
AU2023383916A1 (en) * 2022-11-22 2025-07-10 Janssen Biotech, Inc. Method of treating ulcerative colitis with anti-il23 specific antibody
JP7863690B2 (ja) 2023-03-10 2026-05-21 イーライ リリー アンド カンパニー 潰瘍性大腸炎を治療する方法
JP2026521705A (ja) * 2023-06-16 2026-07-01 イノベント バイオロジクス(スーチョウ)カンパニー,リミティド 炎症性腸疾患の治療における組換え抗インターロイキン23p19サブユニット抗体の使用
AU2025218720A1 (en) 2024-02-06 2026-05-21 Paragon Therapeutics, Inc. Il-23 antibody compositions and methods of use
WO2025171006A1 (en) 2024-02-06 2025-08-14 Paragon Therapeutics, Inc. Il-23 binding protein compositions and methods of use
WO2026060205A1 (en) 2024-09-13 2026-03-19 Eli Lilly And Company PAN-ELR+ CXC CHEMOKINE ANTIBODIES AND IL-23p19 ANTIBODIES FOR THE TREATMENT OF ULCERATIVE COLITIS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2613818C (en) * 2005-06-30 2013-08-27 Centocor, Inc. Anti-il-23 antibodies, compositions, methods and uses
SI3219328T1 (sl) 2005-12-29 2020-10-30 Janssen Biotech, Inc. Človeška protitelesa proti-IL-23, sestavki, postopki in uporabe
HUE042172T2 (hu) 2007-02-23 2019-06-28 Merck Sharp & Dohme Genetikailag elõállított anti-il-23P19 antitestek
EP2352762A1 (en) * 2008-11-03 2011-08-10 Schering Corporation Inflammatory bowel disease biomarkers and related methods of treatment
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
KR102049223B1 (ko) * 2010-11-04 2019-11-28 베링거 인겔하임 인터내셔날 게엠베하 항-il-23 항체
JOP20140049B1 (ar) 2013-03-08 2021-08-17 Lilly Co Eli أجسام مضادة ترتبط بـ il-23
US20170002060A1 (en) * 2014-01-08 2017-01-05 Moderna Therapeutics, Inc. Polynucleotides for the in vivo production of antibodies
JP7516250B2 (ja) * 2018-03-05 2024-07-16 ヤンセン バイオテツク,インコーポレーテツド 抗il-23特異的抗体を用いたクローン病の治療方法

Also Published As

Publication number Publication date
SG11202009526RA (en) 2020-10-29
JP2023166388A (ja) 2023-11-21
PL4327866T3 (pl) 2026-04-20
MD3773715T2 (ro) 2024-10-31
JP7331219B2 (ja) 2023-08-22
MA52216A (fr) 2021-02-17
TW202206104A (zh) 2022-02-16
IL312807B2 (en) 2025-06-01
IL277514B1 (en) 2024-07-01
NZ767902A (en) 2024-05-31
SI3773715T1 (sl) 2024-06-28
TWI837532B (zh) 2024-04-01
RS67806B1 (sr) 2026-03-31
JP2022169562A (ja) 2022-11-09
CA3095297A1 (en) 2019-10-03
DK3773715T3 (da) 2024-05-27
AU2023248103B2 (en) 2026-02-05
JP7571225B2 (ja) 2024-10-22
KR102552693B1 (ko) 2023-07-07
FI3773715T3 (fi) 2024-05-30
MX2020010269A (es) 2020-11-06
JP2021517156A (ja) 2021-07-15
UA128578C2 (uk) 2024-08-21
KR20200128101A (ko) 2020-11-11
IL277514A (en) 2020-11-30
LT4327866T (lt) 2026-03-10
MY202368A (en) 2024-04-24
AU2019243283A1 (en) 2020-09-24
MD4327866T2 (ro) 2026-04-30
IL312807A (en) 2024-07-01
US12152072B2 (en) 2024-11-26
PT3773715T (pt) 2024-05-27
AU2023248103A1 (en) 2023-11-09
DK4327866T3 (da) 2026-02-23
PL3773715T3 (pl) 2024-08-19
EP4327866B1 (en) 2025-12-10
EP3773715A1 (en) 2021-02-17
PT4327866T (pt) 2026-02-17
AU2019243283C1 (en) 2024-05-02
IL312807B1 (en) 2025-02-01
LT3773715T (lt) 2024-06-25
ES2983809T3 (es) 2024-10-24
EP4327866A2 (en) 2024-02-28
MA67901B1 (fr) 2026-02-27
EP3773715B1 (en) 2024-05-08
TWI744617B (zh) 2021-11-01
BR112020018099A2 (pt) 2020-12-22
WO2019191464A1 (en) 2019-10-03
HRP20260275T1 (hr) 2026-04-10
JP7119114B2 (ja) 2022-08-16
ZA202005388B (en) 2025-05-28
JP2025020134A (ja) 2025-02-12
AU2019243283B2 (en) 2023-07-27
IL277514B2 (en) 2024-11-01
HUE067445T2 (hu) 2024-10-28
RS65661B1 (sr) 2024-07-31
AU2026203410A1 (en) 2026-05-21
HRP20240904T1 (hr) 2024-10-11
MA52216B1 (fr) 2024-07-31
ES3063700T3 (en) 2026-04-20
FI4327866T3 (fi) 2026-02-18
US20250034243A1 (en) 2025-01-30
CN111936165A (zh) 2020-11-13
EP4752157A2 (en) 2026-06-03
US20210032325A1 (en) 2021-02-04
TW201946657A (zh) 2019-12-16
EP4327866A3 (en) 2024-03-20
SI4327866T1 (sl) 2026-04-30

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