EA201991472A1 - LOW-MOLECULAR KINASE INHIBITORS JAK FAMILY - Google Patents
LOW-MOLECULAR KINASE INHIBITORS JAK FAMILYInfo
- Publication number
- EA201991472A1 EA201991472A1 EA201991472A EA201991472A EA201991472A1 EA 201991472 A1 EA201991472 A1 EA 201991472A1 EA 201991472 A EA201991472 A EA 201991472A EA 201991472 A EA201991472 A EA 201991472A EA 201991472 A1 EA201991472 A1 EA 201991472A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- low
- kinase inhibitors
- jak family
- molecular kinase
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Соединения 2-((1r,4r)-4-(имидазо[4,5-d]пирроло[2,3-b]пиридин-1(6H)-ил)циклогексил)ацетонитрила, содержащие их фармацевтические композиции, способы их получения и способы их применения, включая способы лечения заболеваний, расстройств и состояний, опосредованных JAK, таких как воспалительное заболевание кишечника.Compounds 2 - ((1r, 4r) -4- (imidazo [4,5-d] pyrrolo [2,3-b] pyridin-1 (6H) -yl) cyclohexyl) acetonitrile, pharmaceutical compositions containing them, methods for their preparation and methods of using them, including methods of treating diseases, disorders and conditions mediated by JAK, such as inflammatory bowel disease.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762596607P | 2017-12-08 | 2017-12-08 | |
PCT/US2017/066744 WO2018112379A1 (en) | 2016-12-16 | 2017-12-15 | Small molecule inhibitors of the jak family of kinases |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201991472A1 true EA201991472A1 (en) | 2019-11-29 |
EA037347B1 EA037347B1 (en) | 2021-03-16 |
Family
ID=68653637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201991472A EA037347B1 (en) | 2017-12-08 | 2017-12-15 | Small molecule inhibitors of the jak family of kinases |
Country Status (1)
Country | Link |
---|---|
EA (1) | EA037347B1 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20140015162A (en) * | 2010-01-12 | 2014-02-06 | 에프. 호프만-라 로슈 아게 | Tricyclic heterocyclic compounds, compositions and methods of use thereof |
WO2013007765A1 (en) * | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Fused tricyclic compounds for use as inhibitors of janus kinases |
-
2017
- 2017-12-15 EA EA201991472A patent/EA037347B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EA037347B1 (en) | 2021-03-16 |
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