EA201600014A1 - Комбинация производного имидазопиридазина и митотического средства для лечения рака - Google Patents
Комбинация производного имидазопиридазина и митотического средства для лечения ракаInfo
- Publication number
- EA201600014A1 EA201600014A1 EA201600014A EA201600014A EA201600014A1 EA 201600014 A1 EA201600014 A1 EA 201600014A1 EA 201600014 A EA201600014 A EA 201600014A EA 201600014 A EA201600014 A EA 201600014A EA 201600014 A1 EA201600014 A1 EA 201600014A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cancer
- combination
- treatment
- mitotic
- imidazopiridazin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к комбинации, содержащей ингибитор киназы Mps-1 и митотический ингибитор. Настоящее изобретение также относится к применению указанной комбинации для лечения рака, в частности рака поджелудочной железы, глиобластомы, рака яичников, немелкоклеточной карциномы легких, рака молочной железы и/или рака желудочно-кишечного тракта.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13171818 | 2013-06-13 | ||
EP13171818.1 | 2013-06-13 | ||
PCT/EP2014/062133 WO2014198776A1 (en) | 2013-06-13 | 2014-06-11 | Combination of a imidazopyridazine derivative and a mitotic agent for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201600014A1 true EA201600014A1 (ru) | 2016-06-30 |
EA028800B1 EA028800B1 (ru) | 2017-12-29 |
Family
ID=48578942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201600014A EA028800B1 (ru) | 2013-06-13 | 2014-06-11 | Комбинация производного имидазопиридазина и митотического средства для лечения рака |
Country Status (17)
Country | Link |
---|---|
US (1) | US20160175306A1 (ru) |
EP (1) | EP3007698A1 (ru) |
JP (1) | JP2016521740A (ru) |
KR (1) | KR20160018749A (ru) |
CN (1) | CN105392484A (ru) |
AP (1) | AP2015008915A0 (ru) |
AU (1) | AU2014280224A1 (ru) |
CA (1) | CA2914995A1 (ru) |
CL (1) | CL2015003606A1 (ru) |
EA (1) | EA028800B1 (ru) |
HK (1) | HK1222341A1 (ru) |
MA (1) | MA38657A1 (ru) |
MX (1) | MX2015017245A (ru) |
PH (1) | PH12015502756A1 (ru) |
SG (1) | SG11201510034QA (ru) |
TN (1) | TN2015000544A1 (ru) |
WO (1) | WO2014198776A1 (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201613927A (en) * | 2014-09-01 | 2016-04-16 | Bayer Pharma AG | Method for preparation of substituted imidazopyridazines |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI541243B (zh) * | 2010-09-10 | 2016-07-11 | 拜耳知識產權公司 | 經取代咪唑并嗒 |
JP6166289B2 (ja) * | 2012-03-14 | 2017-07-19 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | 置換イミダゾピリダジン |
WO2014020041A1 (en) * | 2012-08-02 | 2014-02-06 | Bayer Pharma Aktiengesellschaft | Combinations for the treatment of cancer |
TW201437211A (zh) * | 2013-03-01 | 2014-10-01 | Bayer Pharma AG | 經取代咪唑并嗒□ |
-
2014
- 2014-06-11 AP AP2015008915A patent/AP2015008915A0/xx unknown
- 2014-06-11 EA EA201600014A patent/EA028800B1/ru not_active IP Right Cessation
- 2014-06-11 JP JP2016518995A patent/JP2016521740A/ja active Pending
- 2014-06-11 WO PCT/EP2014/062133 patent/WO2014198776A1/en active Application Filing
- 2014-06-11 CN CN201480042401.1A patent/CN105392484A/zh active Pending
- 2014-06-11 KR KR1020167000489A patent/KR20160018749A/ko not_active Application Discontinuation
- 2014-06-11 AU AU2014280224A patent/AU2014280224A1/en not_active Abandoned
- 2014-06-11 MX MX2015017245A patent/MX2015017245A/es unknown
- 2014-06-11 EP EP14732122.8A patent/EP3007698A1/en not_active Withdrawn
- 2014-06-11 TN TN2015000544A patent/TN2015000544A1/en unknown
- 2014-06-11 CA CA2914995A patent/CA2914995A1/en not_active Abandoned
- 2014-06-11 US US14/898,421 patent/US20160175306A1/en not_active Abandoned
- 2014-06-11 MA MA38657A patent/MA38657A1/fr unknown
- 2014-06-11 SG SG11201510034QA patent/SG11201510034QA/en unknown
-
2015
- 2015-12-10 PH PH12015502756A patent/PH12015502756A1/en unknown
- 2015-12-11 CL CL2015003606A patent/CL2015003606A1/es unknown
-
2016
- 2016-09-07 HK HK16110623.6A patent/HK1222341A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
SG11201510034QA (en) | 2016-01-28 |
TN2015000544A1 (en) | 2017-04-06 |
AU2014280224A1 (en) | 2016-01-07 |
EP3007698A1 (en) | 2016-04-20 |
CA2914995A1 (en) | 2014-12-18 |
EA028800B1 (ru) | 2017-12-29 |
CN105392484A (zh) | 2016-03-09 |
HK1222341A1 (zh) | 2017-06-30 |
MX2015017245A (es) | 2016-07-20 |
PH12015502756A1 (en) | 2016-03-14 |
JP2016521740A (ja) | 2016-07-25 |
MA38657A1 (fr) | 2018-05-31 |
AP2015008915A0 (en) | 2015-12-31 |
US20160175306A1 (en) | 2016-06-23 |
CL2015003606A1 (es) | 2016-08-12 |
KR20160018749A (ko) | 2016-02-17 |
WO2014198776A1 (en) | 2014-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM RU |