EA201591187A1 - Пероральная трансмукозальная доставка ацетата глатирамера - Google Patents
Пероральная трансмукозальная доставка ацетата глатирамераInfo
- Publication number
- EA201591187A1 EA201591187A1 EA201591187A EA201591187A EA201591187A1 EA 201591187 A1 EA201591187 A1 EA 201591187A1 EA 201591187 A EA201591187 A EA 201591187A EA 201591187 A EA201591187 A EA 201591187A EA 201591187 A1 EA201591187 A1 EA 201591187A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- transmusal
- oral
- delivery
- film composition
- acetate glatiramer
- Prior art date
Links
- 108010072051 Glatiramer Acetate Proteins 0.000 title abstract 2
- YLOCGHYTXIINAI-XKUOMLDTSA-N (2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 YLOCGHYTXIINAI-XKUOMLDTSA-N 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 title 1
- 229940042385 glatiramer Drugs 0.000 title 1
- FHEAIOHRHQGZPC-KIWGSFCNSA-N acetic acid;(2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound CC(O)=O.C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 FHEAIOHRHQGZPC-KIWGSFCNSA-N 0.000 abstract 1
- 229960003776 glatiramer acetate Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261745243P | 2012-12-21 | 2012-12-21 | |
| PCT/US2013/077041 WO2014100643A1 (en) | 2012-12-21 | 2013-12-20 | Oral transmucosal delivery of glatiramer acetate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201591187A1 true EA201591187A1 (ru) | 2016-03-31 |
Family
ID=50979258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201591187A EA201591187A1 (ru) | 2012-12-21 | 2013-12-20 | Пероральная трансмукозальная доставка ацетата глатирамера |
Country Status (15)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA025780B1 (ru) | 2010-10-11 | 2017-01-30 | Тева Фармасьютикал Индастриз Лтд. | Цитокиновые биомаркеры в качестве биомаркеров, прогнозирующих клинический ответ на глатирамер ацетат |
| MX2014004309A (es) | 2011-10-10 | 2015-07-06 | Teva Pharma | Polimorfismos de nucleotidos individuales utiles para predecir una respuesta clinica para el acetato de glatiramer. |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| US10493122B2 (en) | 2014-03-17 | 2019-12-03 | Mapi Pharma Ltd. | Sublingual delivery of glatiramer acetate |
| US10323289B2 (en) | 2017-06-26 | 2019-06-18 | Institut Pasteur | Treatments to eliminate HIV reservoirs and reduce viral load |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0679002A (ja) * | 1993-12-14 | 1994-03-22 | Hisamitsu Pharmaceut Co Inc | 経皮投与用パッチシステム |
| US6197331B1 (en) * | 1997-07-24 | 2001-03-06 | Perio Products Ltd. | Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity |
| US7022663B2 (en) * | 2000-02-18 | 2006-04-04 | Yeda Research And Development Co., Ltd. | Oral, nasal and pulmonary dosage formulations of copolymer 1 |
| US20020077278A1 (en) * | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
| US20030175328A1 (en) * | 2002-03-06 | 2003-09-18 | Adi Shefer | Patch for the controlled delivery of cosmetic, dermatological, and pharmaceutical active ingredients into the skin |
| NZ540318A (en) * | 2002-10-31 | 2007-09-28 | Umd Inc | Therapeutic compositions for drug delivery to and through covering epithelia |
| EP2106790B1 (en) * | 2004-03-12 | 2012-10-24 | Biodel, Inc. | Rapid acting drug delivery compositions |
| FI20041425A0 (fi) * | 2004-11-05 | 2004-11-05 | Orion Corp | Transmukosaalinen veterinäärinen koostumus |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| US20060210616A1 (en) * | 2005-03-17 | 2006-09-21 | Linder Barry J | Therapeutic patch for ophthalmologic and cosmetic use |
| US20070021325A1 (en) * | 2005-07-21 | 2007-01-25 | Mediplex Corporation | Drug formulation containing a solubilizer for enhancing solubility, absorption, and permeability |
| US20080027011A1 (en) * | 2005-12-20 | 2008-01-31 | Hassan Nached | Homogeneous paste and gel formulations |
| KR100809404B1 (ko) * | 2005-12-28 | 2008-03-05 | (주)스피어테크 | 리포좀화 시킨 나노용매를 함유하는 경피흡수 점착시트형 화장료 조성물 및 제조방법 |
| WO2007087188A2 (en) * | 2006-01-20 | 2007-08-02 | Merck & Co., Inc. | Taste-masked tablets and granules |
| RU2436565C2 (ru) * | 2006-02-17 | 2011-12-20 | Новартис Аг | Распадающиеся пероральные пленки |
| WO2008006226A1 (en) * | 2006-07-14 | 2008-01-17 | Wine, Harvey | Transdermal formulations of synthetic cannabinoids and nano colloidal silica |
| AU2007329375A1 (en) * | 2006-12-04 | 2008-06-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods to treat cancer with cupredoxins and CpG rich DNA |
| JP5177447B2 (ja) * | 2007-06-07 | 2013-04-03 | 佐藤製薬株式会社 | 速溶性及び可撓性を有するフィルム製剤 |
| WO2009005814A2 (en) * | 2007-07-03 | 2009-01-08 | Marchitto Kevin S | Drug-delivery patch comprising a dissolvable layer and uses thereof |
| US20100278899A1 (en) * | 2007-12-06 | 2010-11-04 | Lintec Corporation | Edible film |
-
2013
- 2013-12-20 EA EA201591187A patent/EA201591187A1/ru unknown
- 2013-12-20 WO PCT/US2013/077041 patent/WO2014100643A1/en not_active Ceased
- 2013-12-20 BR BR112015014092A patent/BR112015014092A2/pt not_active IP Right Cessation
- 2013-12-20 JP JP2015549794A patent/JP2016503066A/ja not_active Withdrawn
- 2013-12-20 KR KR1020157019730A patent/KR20150111919A/ko not_active Withdrawn
- 2013-12-20 AU AU2013361057A patent/AU2013361057A1/en not_active Abandoned
- 2013-12-20 MX MX2015007794A patent/MX2015007794A/es unknown
- 2013-12-20 CN CN201380067117.5A patent/CN104869984A/zh active Pending
- 2013-12-20 SG SG11201504461QA patent/SG11201504461QA/en unknown
- 2013-12-20 HK HK16102543.0A patent/HK1214522A1/zh unknown
- 2013-12-20 US US14/653,013 patent/US20150328277A1/en not_active Abandoned
- 2013-12-20 CA CA2895457A patent/CA2895457A1/en not_active Abandoned
- 2013-12-20 HK HK16102019.5A patent/HK1214133A1/zh unknown
- 2013-12-20 EP EP13866153.3A patent/EP2934493A4/en not_active Withdrawn
-
2015
- 2015-06-08 IL IL239279A patent/IL239279A0/en unknown
- 2015-07-14 ZA ZA2015/05050A patent/ZA201505050B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014100643A1 (en) | 2014-06-26 |
| JP2016503066A (ja) | 2016-02-01 |
| ZA201505050B (en) | 2016-10-26 |
| CN104869984A (zh) | 2015-08-26 |
| SG11201504461QA (en) | 2015-07-30 |
| HK1214522A1 (zh) | 2016-07-29 |
| WO2014100643A8 (en) | 2015-06-25 |
| EP2934493A4 (en) | 2016-09-07 |
| HK1214133A1 (zh) | 2016-07-22 |
| EP2934493A1 (en) | 2015-10-28 |
| CA2895457A1 (en) | 2014-06-26 |
| US20150328277A1 (en) | 2015-11-19 |
| AU2013361057A1 (en) | 2015-07-30 |
| BR112015014092A2 (pt) | 2017-07-11 |
| KR20150111919A (ko) | 2015-10-06 |
| MX2015007794A (es) | 2015-09-04 |
| IL239279A0 (en) | 2015-07-30 |
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