EA201591103A1 - Полоксамеры с удлиненной цепью, получаемые из них термообратимые гидрогели, содержащие биологические вещества, и их применение в медицине - Google Patents

Полоксамеры с удлиненной цепью, получаемые из них термообратимые гидрогели, содержащие биологические вещества, и их применение в медицине

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Publication number
EA201591103A1
EA201591103A1 EA201591103A EA201591103A EA201591103A1 EA 201591103 A1 EA201591103 A1 EA 201591103A1 EA 201591103 A EA201591103 A EA 201591103A EA 201591103 A EA201591103 A EA 201591103A EA 201591103 A1 EA201591103 A1 EA 201591103A1
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EA
Eurasian Patent Office
Prior art keywords
reversible hydrogels
extractive
medicine
thermal
application
Prior art date
Application number
EA201591103A
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English (en)
Inventor
Маттиас Шикер
Хинрих Визе
Ута Молль
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Маттиас Шикер
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Application filed by Маттиас Шикер filed Critical Маттиас Шикер
Publication of EA201591103A1 publication Critical patent/EA201591103A1/ru

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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Abstract

Согласно настоящему изобретению из полоксамеров с удлиненной цепью получены термообратимые гидрогели с улучшенными свойствами. Кроме того, изобретение обеспечивает термообратимые гидрогели с биологическими материалами и способ их получения, термообратимые гидрогели, содержащие живые клетки, аппликационные системы для фармацевтических применений, а также осуществляемый in vitro способ формирования композиции на поверхности.
EA201591103A 2012-12-17 2013-12-17 Полоксамеры с удлиненной цепью, получаемые из них термообратимые гидрогели, содержащие биологические вещества, и их применение в медицине EA201591103A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201210223416 DE102012223416A1 (de) 2012-12-17 2012-12-17 Kettenverlängerte Poloxamere, daraus gebildete thermoreversible Hydrogele mit biologischen Materialien, und medizinische Anwendungen derselben
PCT/EP2013/076966 WO2014095915A1 (de) 2012-12-17 2013-12-17 Kettenverlängerte poloxamere, daraus gebildete thermoreversible hydrogele mit biologischen materialien, und medizinische anwendungen derselben

Publications (1)

Publication Number Publication Date
EA201591103A1 true EA201591103A1 (ru) 2016-01-29

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EA201591103A EA201591103A1 (ru) 2012-12-17 2013-12-17 Полоксамеры с удлиненной цепью, получаемые из них термообратимые гидрогели, содержащие биологические вещества, и их применение в медицине

Country Status (13)

Country Link
US (1) US10406231B2 (ru)
EP (1) EP2931775B1 (ru)
JP (1) JP2016509610A (ru)
CN (1) CN104903373A (ru)
AU (1) AU2013360861B2 (ru)
BR (1) BR112015014158A2 (ru)
CA (1) CA2895437C (ru)
DE (1) DE102012223416A1 (ru)
EA (1) EA201591103A1 (ru)
IL (1) IL239471A0 (ru)
SG (1) SG11201504800SA (ru)
WO (1) WO2014095915A1 (ru)
ZA (1) ZA201504353B (ru)

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ITUB20155342A1 (it) * 2015-11-06 2017-05-06 Emenem Srl Composizione di soluzioni-gel reversibili termosensibili mucoadesive a base di collagene e sali di acido ialuronico
WO2017192753A1 (en) * 2016-05-03 2017-11-09 Bvw Holding Ag Multiphase gel
EP3381479A1 (de) 2017-03-29 2018-10-03 ARTOSS GmbH Trägerzusammensetzung für knochenersatzmaterialien
WO2020209740A1 (en) 2019-04-12 2020-10-15 Institutul De Chimie Macromoleculară Petru Poni Non-isocyanate polyurethane thermoreversible hydrogel and method for its preparation
AU2020340765B2 (en) * 2019-09-06 2024-02-15 International Frontier Technology Laboratory, Inc. Composition comprising thermosensitive gel and oligopeptide and use thereof
TWI777517B (zh) * 2020-04-24 2022-09-11 博唯弘展生技股份有限公司 用於預防沾黏之胺基酸改質的聚合物及其應用
CN111875775B (zh) * 2020-07-22 2022-09-16 上海华峰超纤科技股份有限公司 一种制备抗菌聚氨酯树脂及聚氨酯合成革的方法
CN111921017A (zh) * 2020-08-07 2020-11-13 上海维洱生物医药科技有限公司 一种原位在体凝胶制剂的制备和在内镜黏膜下切除和剥离术中的应用
CN115403760B (zh) * 2021-05-26 2023-10-03 博唯弘展生技股份有限公司 用于预防沾粘的氨基酸改质的聚合物及其应用
CN115073699B (zh) * 2022-06-14 2024-01-26 杭州柏医健康科技有限公司 一种温度不敏感的聚氨酯聚合物及应用
CN115536833A (zh) * 2022-08-02 2022-12-30 深圳先进技术研究院 一种兼具快速固化和抗溶胀的可注射水凝胶粘合剂及应用
CN115414278A (zh) * 2022-08-29 2022-12-02 中国人民解放军空军军医大学 仿生纳米黑色素光热性日光性防护剂的制备方法与应用
CN115873231A (zh) * 2022-12-17 2023-03-31 华南理工大学 一种聚乙二醇修饰的氨基糖苷类分子及其制备方法和应用

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SG11201504800SA (en) 2015-07-30
AU2013360861A1 (en) 2015-07-30
DE102012223416A8 (de) 2015-03-12
IL239471A0 (en) 2015-07-30
AU2013360861B2 (en) 2017-06-15
EP2931775B1 (de) 2021-04-21
WO2014095915A1 (de) 2014-06-26
CN104903373A (zh) 2015-09-09
CA2895437A1 (en) 2014-06-26
BR112015014158A2 (pt) 2017-07-11
US10406231B2 (en) 2019-09-10
US20150335749A1 (en) 2015-11-26
ZA201504353B (en) 2016-07-27

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