EA201490613A1 - Соединения с замедляющим старение действием - Google Patents
Соединения с замедляющим старение действиемInfo
- Publication number
- EA201490613A1 EA201490613A1 EA201490613A EA201490613A EA201490613A1 EA 201490613 A1 EA201490613 A1 EA 201490613A1 EA 201490613 A EA201490613 A EA 201490613A EA 201490613 A EA201490613 A EA 201490613A EA 201490613 A1 EA201490613 A1 EA 201490613A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- skin
- sign
- aging
- compound
- aging action
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000003679 aging effect Effects 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 abstract 2
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- 230000009759 skin aging Effects 0.000 abstract 2
- 230000037380 skin damage Effects 0.000 abstract 2
- AXNVHPCVMSNXNP-IVKVKCDBSA-N (2s,3s,4s,5r,6r)-6-[[(3s,4s,4ar,6ar,6bs,8r,8ar,9r,10r,12as,14ar,14br)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(e)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3, Chemical compound O([C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2[C@]1(CO)C)C)(C)C[C@@H](O)[C@@]1(CO)[C@@H](OC(C)=O)[C@@H](C(C[C@H]14)(C)C)OC(=O)C(/C)=C/C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O AXNVHPCVMSNXNP-IVKVKCDBSA-N 0.000 abstract 1
- AXNVHPCVMSNXNP-GKTCLTPXSA-N Aescin Natural products O=C(O[C@H]1[C@@H](OC(=O)C)[C@]2(CO)[C@@H](O)C[C@@]3(C)[C@@]4(C)[C@@H]([C@]5(C)[C@H]([C@](CO)(C)[C@@H](O[C@@H]6[C@@H](O[C@H]7[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)[C@@H](O)[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O7)[C@@H](C(=O)O)O6)CC5)CC4)CC=C3[C@@H]2CC1(C)C)/C(=C/C)/C AXNVHPCVMSNXNP-GKTCLTPXSA-N 0.000 abstract 1
- -1 N-acetyl aspartic acids Chemical class 0.000 abstract 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 abstract 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 abstract 1
- JMFSHKGXVSAJFY-UHFFFAOYSA-N Saponaretin Natural products OCC(O)C1OC(Oc2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)cc4)C(O)C1O JMFSHKGXVSAJFY-UHFFFAOYSA-N 0.000 abstract 1
- MOZJVOCOKZLBQB-UHFFFAOYSA-N Vitexin Natural products OCC1OC(Oc2c(O)c(O)cc3C(=O)C=C(Oc23)c4ccc(O)cc4)C(O)C(O)C1O MOZJVOCOKZLBQB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- 229940093314 beta-escin Drugs 0.000 abstract 1
- AXNVHPCVMSNXNP-BEJCRFBNSA-N beta-escin Natural products CC=C(/C)C(=O)O[C@H]1[C@H](OC(=O)C)[C@]2(CO)[C@H](O)C[C@@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@H]6O[C@@H]([C@H](O[C@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2CC1(C)C AXNVHPCVMSNXNP-BEJCRFBNSA-N 0.000 abstract 1
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 1
- 210000003128 head Anatomy 0.000 abstract 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 abstract 1
- 235000007625 naringenin Nutrition 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 229960001285 quercetin Drugs 0.000 abstract 1
- 235000005875 quercetin Nutrition 0.000 abstract 1
- 210000004761 scalp Anatomy 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- SGEWCQFRYRRZDC-VPRICQMDSA-N vitexin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=C(O)C2=C1OC(C=1C=CC(O)=CC=1)=CC2=O SGEWCQFRYRRZDC-VPRICQMDSA-N 0.000 abstract 1
- PZKISQRTNNHUGF-UHFFFAOYSA-N vitexine Natural products OC1C(O)C(O)C(CO)OC1OC1=C(O)C=C(O)C2=C1OC(C=1C=CC(O)=CC=1)=CC2=O PZKISQRTNNHUGF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/42—Amides
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
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- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
Нетерапевтическое применение в косметологии или дерматологии по меньшей мере одного соединения, выбранного из группы, состоящей из гибберелловых кислот, нарингенинов, N-ацетиласпарагиновых кислот, β-эсцина, арахидоновой кислоты, кверцетина, витексина и докозагексаеновой кислоты (этиловый эфир). Соответственно, указанное применение имеет место при лечении и/или профилактике по меньшей мере одного признака старения кожи или по меньшей мере одного признака повреждения кожи, связанного со старением, причем указанный признак старения кожи или повреждения кожи наблюдается на коже лица, тела или коже волосистой части головы субъекта.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2011/073484 WO2013091684A1 (en) | 2011-12-20 | 2011-12-20 | Compounds with anti-aging activities |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201490613A1 true EA201490613A1 (ru) | 2014-12-30 |
EA031552B1 EA031552B1 (ru) | 2019-01-31 |
Family
ID=45349522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201490613A EA031552B1 (ru) | 2011-12-20 | 2011-12-20 | Нетерапевтическое косметическое местное применение n-ацетил-l-аспарагиновой кислоты |
Country Status (8)
Country | Link |
---|---|
US (1) | US20140301961A1 (ru) |
EP (3) | EP2862600B1 (ru) |
CN (1) | CN104254370A (ru) |
CL (1) | CL2014001661A1 (ru) |
EA (1) | EA031552B1 (ru) |
MX (1) | MX352165B (ru) |
PL (1) | PL2729220T3 (ru) |
WO (1) | WO2013091684A1 (ru) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140276354A1 (en) * | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
FR3007981B1 (fr) * | 2013-07-05 | 2016-01-22 | Oreal | Association d'extrait d'hamamelis virginiana, d'escine, et d'acide ascorbique |
KR102401730B1 (ko) | 2015-04-01 | 2022-05-26 | 킴벌리-클라크 월드와이드, 인크. | 그람 음성 박테리아 포획용 섬유 기재 |
KR101762111B1 (ko) * | 2015-07-06 | 2017-07-28 | 코스맥스 주식회사 | 동규자 추출물을 함유하는 피부노화 또는 피부주름 개선용 화장료 조성물 |
EP3158989A3 (en) * | 2017-02-01 | 2017-10-11 | SanderStrothmann GmbH | Cosmetic skin treatment composition |
CN107468533A (zh) * | 2017-08-22 | 2017-12-15 | 广州聚注通用技术研究院有限公司 | 具有抗辐射美白活性的雪莲槲皮素及其制备方法和应用 |
US11376797B2 (en) | 2018-01-16 | 2022-07-05 | Hewlett-Packard Development Company, L.P. | Three dimensional printing system |
EP3524409A1 (en) * | 2018-02-09 | 2019-08-14 | CL Schutzrechtsverwaltungs GmbH | Apparatus for additively manufacturing three-dimensional objects |
CN108616573A (zh) * | 2018-03-31 | 2018-10-02 | 甘肃万维信息技术有限责任公司 | 基于区块链互联的精准扶贫便民服务系统 |
CN110354073B (zh) * | 2018-04-09 | 2021-10-01 | 鲁南制药集团股份有限公司 | 一种免疫抑制剂单克隆抗体的液体制剂 |
ES2689105B8 (es) * | 2018-04-30 | 2019-05-28 | Monteloeder S L | Composición de extractos vegetales con flavonoides para paliar los múltiples efectos de la contaminación del aire sobre la piel |
KR102187439B1 (ko) * | 2019-01-30 | 2020-12-07 | 주식회사 라파스 | 마이크로니들 패취를 이용한 최소 침습적 피부 생체 검사 방법 |
RU2750420C1 (ru) * | 2020-11-23 | 2021-06-28 | Андрей Александрович Васильевых | Масляная композиция для получения косметических средств |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4297348A (en) * | 1980-04-11 | 1981-10-27 | Rush-Hampton Industries, Inc. | Composition and method for the treatment of acne |
EP0126138A1 (en) * | 1982-11-04 | 1984-11-28 | Redken Laboratories Inc. | Cosmetic preparation |
US5449794A (en) * | 1991-02-15 | 1995-09-12 | Jasmine Fockerman | Benzopyran phenol derivatives for use as antibacterial agents |
DE4444238A1 (de) * | 1994-12-13 | 1996-06-20 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden |
NZ299379A (en) * | 1995-10-27 | 1997-04-24 | Unilever Plc | Topical flavanone-containing composition |
US5851538A (en) | 1995-12-29 | 1998-12-22 | Advanced Polymer Systems, Inc. | Retinoid formulations in porous microspheres for reduced irritation and enhanced stability |
ES2237789T3 (es) | 1996-01-31 | 2005-08-01 | Cosmoferm B.V. | Utilizacion de composiciones que comprenden enzimas estabilizantes. |
US5665367A (en) * | 1996-09-27 | 1997-09-09 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Skin care compositions containing naringenin and/or quercetin and a retinoid |
US6103267A (en) | 1998-07-27 | 2000-08-15 | Sunsmart, Inc. | Stabilized ascorbic acid, composition, and method of use |
US6159485A (en) * | 1999-01-08 | 2000-12-12 | Yugenic Limited Partnership | N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use |
US7758888B2 (en) | 2000-04-21 | 2010-07-20 | Sol-Gel Technologies Ltd. | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients |
EP1438059A4 (en) * | 2001-10-26 | 2008-01-23 | Angiolab Inc | COMPOSITION CONTAINING EXTRACT OF BROWN FROM INDIA PREPARED FOR ANTI-ANGIOGENIC ACTIVITY AND INHIBITOR OF MATRIX METALLOPROTEINASE |
US7098189B2 (en) * | 2002-12-16 | 2006-08-29 | Kimberly-Clark Worldwide, Inc. | Wound and skin care compositions |
US20050192348A1 (en) * | 2003-09-25 | 2005-09-01 | David Bar-Or | Methods and products which utilize N-acyl-L-aspartic acid |
US20050171194A1 (en) * | 2003-12-08 | 2005-08-04 | Yu Ruey J. | Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions |
JP4138679B2 (ja) * | 2004-02-25 | 2008-08-27 | 株式会社資生堂 | 刺激緩和剤 |
MX2009008334A (es) * | 2007-02-05 | 2009-08-12 | Nicox Sa | Esteroides que liberan oxido nitrico. |
GB0817936D0 (en) | 2008-09-30 | 2008-11-05 | Intrinsiq Materials Global Ltd | Porous materials |
US20100286271A1 (en) * | 2009-05-08 | 2010-11-11 | Perricone Nicholas V | Nitro-alkyl Compound Compositions |
DE102009034999A1 (de) | 2009-07-27 | 2011-02-03 | Robert Dietrich | Steuerungshilfsvorrichtung für frei ausfliegende Windangriffselemente mit einer Tragflächengröße von mehr als 20 m2 |
US20120201903A1 (en) * | 2009-10-09 | 2012-08-09 | Oregon Health & Science University | Cytoprotective or therapeutic plant composition |
FR2958154B1 (fr) | 2010-04-01 | 2012-06-08 | Oreal | Procede de soin et/ou de maquillage des rides |
-
2011
- 2011-12-20 EA EA201490613A patent/EA031552B1/ru not_active IP Right Cessation
- 2011-12-20 EP EP14196664.8A patent/EP2862600B1/en active Active
- 2011-12-20 WO PCT/EP2011/073484 patent/WO2013091684A1/en active Application Filing
- 2011-12-20 EP EP11797020.2A patent/EP2729220B1/en active Active
- 2011-12-20 EP EP14196665.5A patent/EP2886163A1/en not_active Withdrawn
- 2011-12-20 MX MX2014007495A patent/MX352165B/es active IP Right Grant
- 2011-12-20 CN CN201180075778.3A patent/CN104254370A/zh active Pending
- 2011-12-20 PL PL11797020T patent/PL2729220T3/pl unknown
-
2014
- 2014-06-19 US US14/309,596 patent/US20140301961A1/en not_active Abandoned
- 2014-06-20 CL CL2014001661A patent/CL2014001661A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN104254370A (zh) | 2014-12-31 |
WO2013091684A1 (en) | 2013-06-27 |
EA031552B1 (ru) | 2019-01-31 |
MX2014007495A (es) | 2015-05-08 |
EP2862600A1 (en) | 2015-04-22 |
EP2886163A1 (en) | 2015-06-24 |
EP2862600B1 (en) | 2020-02-12 |
CL2014001661A1 (es) | 2015-03-06 |
PL2729220T3 (pl) | 2016-05-31 |
US20140301961A1 (en) | 2014-10-09 |
EP2729220A1 (en) | 2014-05-14 |
MX352165B (es) | 2017-11-13 |
EP2729220B1 (en) | 2015-11-04 |
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