EA201170219A1 - Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих - Google Patents

Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих

Info

Publication number
EA201170219A1
EA201170219A1 EA201170219A EA201170219A EA201170219A1 EA 201170219 A1 EA201170219 A1 EA 201170219A1 EA 201170219 A EA201170219 A EA 201170219A EA 201170219 A EA201170219 A EA 201170219A EA 201170219 A1 EA201170219 A1 EA 201170219A1
Authority
EA
Eurasian Patent Office
Prior art keywords
defensins
treatment
beta
intestine
mammals
Prior art date
Application number
EA201170219A
Other languages
English (en)
Russian (ru)
Inventor
Таня Мария Росенкилле Кьер
Томас Крусе
Пер Хольсе Мюгинн
Каролине Сидельманн Бринч
Серен Кьерульфф
Биргитте Андерсен
Original Assignee
Новозимс Эдениум Байотек А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41530820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201170219(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Новозимс Эдениум Байотек А/С filed Critical Новозимс Эдениум Байотек А/С
Publication of EA201170219A1 publication Critical patent/EA201170219A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1729—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201170219A 2008-07-18 2009-07-17 Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих EA201170219A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08160761 2008-07-18
EP08162486 2008-08-15
EP08163614 2008-09-03
PCT/EP2009/059253 WO2010007166A2 (en) 2008-07-18 2009-07-17 Treatment of inflammatory bowel diseases with mammal beta defensins

Publications (1)

Publication Number Publication Date
EA201170219A1 true EA201170219A1 (ru) 2011-08-30

Family

ID=41530820

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201100910A EA201100910A1 (ru) 2008-07-18 2009-07-17 Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих
EA201170219A EA201170219A1 (ru) 2008-07-18 2009-07-17 Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201100910A EA201100910A1 (ru) 2008-07-18 2009-07-17 Лечение воспалительных заболеваний кишечника бета-дефенсинами млекопитающих

Country Status (20)

Country Link
US (4) US8232242B2 (enExample)
EP (2) EP2320930A2 (enExample)
JP (2) JP2011528333A (enExample)
KR (1) KR20110092325A (enExample)
CN (2) CN102247591A (enExample)
AP (2) AP2011005538A0 (enExample)
AR (2) AR072032A1 (enExample)
AU (1) AU2009272681A1 (enExample)
BR (2) BRPI0915973A2 (enExample)
CA (2) CA2730789A1 (enExample)
CL (1) CL2011000099A1 (enExample)
EA (2) EA201100910A1 (enExample)
IL (2) IL210715A0 (enExample)
MX (1) MX2011000568A (enExample)
NZ (2) NZ593653A (enExample)
PH (1) PH12012501542A1 (enExample)
SG (1) SG172709A1 (enExample)
TW (2) TW201004640A (enExample)
WO (1) WO2010007166A2 (enExample)
ZA (1) ZA201100461B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011528334A (ja) * 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療
US20100016232A1 (en) * 2008-07-18 2010-01-21 Novozymes A/S Treatment Of Inflammatory Diseases With Mammal Beta Defensins
AR072032A1 (es) 2008-07-18 2010-07-28 Novozymes As Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos
KR101320472B1 (ko) * 2010-06-16 2013-10-23 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
EP3501284A1 (en) 2011-04-15 2019-06-26 Marine Polymer Technologies, Inc. Treatment of skin deseases with poly-n-acetyl glucosamine nanofibers
US9217021B2 (en) 2011-07-08 2015-12-22 Defensin Therapeutics Aps Oral treatment of inflammatory bowel disease
WO2013026794A1 (en) 2011-08-19 2013-02-28 Novozymes Novel immunomodulatory peptide
US10257564B2 (en) * 2013-01-24 2019-04-09 Saturn Licensing Llc Distributed non-real-time content
CN104628864B (zh) * 2013-11-14 2020-04-10 中国医学科学院医药生物技术研究所 一种抗肿瘤融合蛋白EL-defensin、其编码基因和用途
CN109414474B (zh) * 2016-04-29 2024-07-02 诺维信公司 肝脏、胆道和胰腺障碍的治疗
SG10202012106WA (en) 2016-12-13 2021-01-28 Defensin Therapeutics Aps Methods for treating inflammatory conditions of the lungs
CN111556759A (zh) * 2017-11-10 2020-08-18 防御素治疗学公司 早产儿中的粘膜防御和肠道/肺功能的成熟化
EP3713590B1 (en) 2017-11-24 2025-05-07 Defensin Therapeutics ApS Human beta 2 defensin for use in the prevention and treatment of graft-versus-host-disease
KR102244161B1 (ko) * 2018-08-31 2021-04-26 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
CN113684162B (zh) * 2021-06-03 2024-02-27 江南大学 一种表达小鼠防御素mBD14基因的重组植物乳杆菌及其应用
WO2024225153A1 (ja) * 2023-04-27 2024-10-31 サントリーホールディングス株式会社 免疫活性化用組成物

Family Cites Families (20)

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US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6576755B1 (en) * 1997-09-10 2003-06-10 Zymogenetics, Inc. Beta-defensins
DE19957043A1 (de) * 1999-11-26 2001-06-07 Forssmann Wolf Georg Neue Defensine
US7338936B2 (en) * 2000-11-28 2008-03-04 House Ear Institute Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
FR2841556B1 (fr) 2002-07-01 2007-07-20 Centre Nat Rech Scient Peptides ayant des proprietes antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments
JP2006514106A (ja) * 2002-12-19 2006-04-27 ヒルマン，イチャク 抗菌ペプチド阻害剤による疾患治療
US20070207209A1 (en) 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
GB0514482D0 (en) 2005-07-14 2005-08-17 Ares Trading Sa Protein
WO2007081486A2 (en) 2005-12-15 2007-07-19 Ventria Bioscience Oral administration of defensins to treat intestinal diseases
CA2676483A1 (en) 2006-01-24 2007-08-02 University Of Maryland Biotechnology Institute Surface-layer protein coated microspheres and uses thereof
WO2009033776A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a defensin peptide as a therapeutic agent
US20100016232A1 (en) * 2008-07-18 2010-01-21 Novozymes A/S Treatment Of Inflammatory Diseases With Mammal Beta Defensins
AR072032A1 (es) 2008-07-18 2010-07-28 Novozymes As Tratamiento de enfermedades inflamatorias del intestino con beta defensinas de mamiferos
JP2011528334A (ja) 2008-07-18 2011-11-17 ノボザイムス アデニウム バイオテック アクティーゼルスカブ 哺乳動物のベータ・ディフェンシンを用いた、関節リウマチの治療
US9217021B2 (en) 2011-07-08 2015-12-22 Defensin Therapeutics Aps Oral treatment of inflammatory bowel disease
WO2013026794A1 (en) 2011-08-19 2013-02-28 Novozymes Novel immunomodulatory peptide

Also Published As

Publication number Publication date
CA2730789A1 (en) 2010-01-21
US9279010B2 (en) 2016-03-08
US20110251139A1 (en) 2011-10-13
JP2011528333A (ja) 2011-11-17
CN102247591A (zh) 2011-11-23
US20100016230A1 (en) 2010-01-21
AR081948A2 (es) 2012-10-31
CA2750727A1 (en) 2010-01-21
IL210715A0 (en) 2011-03-31
US8802621B2 (en) 2014-08-12
IL213680A0 (en) 2011-07-31
BRPI0915973A2 (pt) 2013-05-07
CN102159233A (zh) 2011-08-17
MX2011000568A (es) 2011-02-23
NZ593653A (en) 2012-09-28
SG172709A1 (en) 2011-07-28
US20140135258A1 (en) 2014-05-15
NZ590468A (en) 2012-06-29
AP2011005538A0 (en) 2011-02-28
WO2010007166A3 (en) 2010-06-03
US8232242B2 (en) 2012-07-31
WO2010007166A2 (en) 2010-01-21
EP2399600A1 (en) 2011-12-28
AU2009272681A1 (en) 2010-01-21
JP2011225596A (ja) 2011-11-10
EP2320930A2 (en) 2011-05-18
BRPI0924481A2 (pt) 2015-08-11
ZA201100461B (en) 2014-03-26
US20120309678A1 (en) 2012-12-06
TW201004640A (en) 2010-02-01
AR072032A1 (es) 2010-07-28
CL2011000099A1 (es) 2011-10-07
KR20110092325A (ko) 2011-08-17
PH12012501542A1 (en) 2015-11-09
EA201100910A1 (ru) 2012-05-30
AP2011005755A0 (en) 2011-06-30
TW201138810A (en) 2011-11-16

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