EA201170136A1 - Мультимасштабный метод конечных объемов для моделирования резервуара - Google Patents
Мультимасштабный метод конечных объемов для моделирования резервуараInfo
- Publication number
- EA201170136A1 EA201170136A1 EA201170136A EA201170136A EA201170136A1 EA 201170136 A1 EA201170136 A1 EA 201170136A1 EA 201170136 A EA201170136 A EA 201170136A EA 201170136 A EA201170136 A EA 201170136A EA 201170136 A1 EA201170136 A1 EA 201170136A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- present
- relates
- reservoire
- modeling
- cancer
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F30/00—Computer-aided design [CAD]
- G06F30/20—Design optimisation, verification or simulation
- G06F30/23—Design optimisation, verification or simulation using finite element methods [FEM] or finite difference methods [FDM]
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2111/00—Details relating to CAD techniques
- G06F2111/10—Numerical modelling
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- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Computer Hardware Design (AREA)
- Evolutionary Computation (AREA)
- Geometry (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Настоящее изобретение относится к композициям и способам их применения для исследования, диагностики и лечения рака. В частности, настоящее изобретение относится к средствам и способам диагностики, исследования, прогнозирования и лечения рака и специфически направленного воздействия на раковые стволовые клетки. Настоящее изобретение относится к антителу, которое специфически связывается с нелигандсвязывающей проксимальной областью мембраны внеклеточного домена рецептора Notch1 человека и ингибирует рост опухоли. Настоящее изобретение далее относится к способу лечения рака, включающему введение терапевтически эффективного количества антитела, которое специфически связывается с нелигандсвязывающей проксимальной областью мембраны внеклеточного домена белка рецептора Notch1 человека и ингибирует рост опухоли.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7796108P | 2008-07-03 | 2008-07-03 | |
PCT/US2009/049423 WO2010003004A2 (en) | 2008-07-03 | 2009-07-01 | Multi-scale finite volume method for reservoir simulation |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201170136A1 true EA201170136A1 (ru) | 2011-08-30 |
Family
ID=41465051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201170136A EA201170136A1 (ru) | 2008-07-03 | 2009-07-01 | Мультимасштабный метод конечных объемов для моделирования резервуара |
Country Status (8)
Country | Link |
---|---|
US (1) | US8594986B2 (ru) |
EP (1) | EP2310972A2 (ru) |
AU (1) | AU2009266935B2 (ru) |
BR (1) | BRPI0914102A2 (ru) |
CA (1) | CA2729770C (ru) |
EA (1) | EA201170136A1 (ru) |
MX (1) | MX2011000115A (ru) |
WO (1) | WO2010003004A2 (ru) |
Families Citing this family (20)
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CA2716539C (en) * | 2008-03-28 | 2015-07-21 | Exxonmobil Upstream Research Company | Computing a consistent velocity vector field from a set of fluxes |
AU2009244726B2 (en) | 2008-05-05 | 2014-04-24 | Exxonmobil Upstream Research Company | Modeling dynamic systems by visualizing and narrowing a parameter space |
AU2009302317A1 (en) * | 2008-10-09 | 2010-04-15 | Chevron U.S.A. Inc. | Iterative multi-scale method for flow in porous media |
EP2494385A2 (en) * | 2009-10-28 | 2012-09-05 | Chevron U.S.A. Inc. | Multiscale finite volume method for reservoir simulation |
BR112012011970A2 (pt) * | 2009-11-23 | 2016-05-10 | Exxonmobil Upstream Res Co | método e sistema para modelagem de propriedades geológicas utilizando elementos finitos mistos e homogeneizados |
EP2564309A4 (en) * | 2010-04-30 | 2017-12-20 | Exxonmobil Upstream Research Company | Method and system for finite volume simulation of flow |
CA2803068C (en) * | 2010-07-29 | 2016-10-11 | Exxonmobil Upstream Research Company | Method and system for reservoir modeling |
WO2012071090A1 (en) | 2010-11-23 | 2012-05-31 | Exxonmobil Upstream Research Company | Variable discretization method for flow simulation on complex geological models |
US9753180B2 (en) | 2012-03-28 | 2017-09-05 | Exxonmobil Upstream Research Company | Method for multiphase flow upscaling |
CA2883169C (en) | 2012-09-28 | 2021-06-15 | Exxonmobil Upstream Research Company | Fault removal in geological models |
WO2015195129A1 (en) * | 2014-06-19 | 2015-12-23 | Landmark Graphics Corporation | Multi-stage linear solution for implicit reservoir simulation |
US10914864B2 (en) | 2014-07-16 | 2021-02-09 | Schlumberger Technology Corporation | Multiscale method for reservoir models |
AU2015298233B2 (en) | 2014-07-30 | 2018-02-22 | Exxonmobil Upstream Research Company | Method for volumetric grid generation in a domain with heterogeneous material properties |
US10359523B2 (en) | 2014-08-05 | 2019-07-23 | Exxonmobil Upstream Research Company | Exploration and extraction method and system for hydrocarbons |
WO2016070073A1 (en) | 2014-10-31 | 2016-05-06 | Exxonmobil Upstream Research Company | Managing discontinuities in geologic models |
US10534877B2 (en) * | 2015-05-19 | 2020-01-14 | Schlumberger Technology Corporation | Adaptive multiscale multi-fidelity reservoir simulation |
US10280722B2 (en) | 2015-06-02 | 2019-05-07 | Baker Hughes, A Ge Company, Llc | System and method for real-time monitoring and estimation of intelligent well system production performance |
CA3001187C (en) * | 2015-10-09 | 2024-01-09 | Schlumberger Canada Limited | Reservoir simulation using an adaptive deflated multiscale solver |
WO2018118374A1 (en) | 2016-12-23 | 2018-06-28 | Exxonmobil Upstream Research Company | Method and system for stable and efficient reservoir simulation using stability proxies |
WO2021212059A1 (en) * | 2020-04-17 | 2021-10-21 | Chevron U.S.A. Inc. | Compositional reservoir simulation |
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US4821164A (en) | 1986-07-25 | 1989-04-11 | Stratamodel, Inc. | Process for three-dimensional mathematical modeling of underground geologic volumes |
US5321612A (en) | 1991-02-26 | 1994-06-14 | Swift Energy Company | Method for exploring for hydrocarbons utilizing three dimensional modeling of thermal anomalies |
FR2726091B1 (fr) | 1994-10-19 | 1996-12-20 | Elf Aquitaine | Methode d'analyse et de traitement de donnees sismiques reflexion pour la determination d'un champ fin de vitesse de correction d'hyperbolicite |
US5729451A (en) | 1995-12-01 | 1998-03-17 | Coleman Research Corporation | Apparatus and method for fusing diverse data |
US5923329A (en) | 1996-06-24 | 1999-07-13 | National Research Council Of Canada | Method of grid generation about or within a 3 dimensional object |
US6018497A (en) | 1997-02-27 | 2000-01-25 | Geoquest | Method and apparatus for generating more accurate earth formation grid cell property information for use by a simulator to display more accurate simulation results of the formation near a wellbore |
US6106561A (en) | 1997-06-23 | 2000-08-22 | Schlumberger Technology Corporation | Simulation gridding method and apparatus including a structured areal gridder adapted for use by a reservoir simulator |
GB2336008B (en) | 1998-04-03 | 2000-11-08 | Schlumberger Holdings | Simulation system including a simulator and a case manager adapted for organizing data files |
WO1999057418A1 (en) | 1998-05-04 | 1999-11-11 | Schlumberger Evaluation & Production (Uk) Services | Near wellbore modeling method and apparatus |
US6721694B1 (en) | 1998-10-13 | 2004-04-13 | Raytheon Company | Method and system for representing the depths of the floors of the oceans |
US6185512B1 (en) | 1998-10-13 | 2001-02-06 | Raytheon Company | Method and system for enhancing the accuracy of measurements of a physical quantity |
US6826520B1 (en) | 1999-06-24 | 2004-11-30 | Exxonmobil Upstream Research Company | Method of upscaling permeability for unstructured grids |
US6266619B1 (en) | 1999-07-20 | 2001-07-24 | Halliburton Energy Services, Inc. | System and method for real time reservoir management |
US7006959B1 (en) | 1999-10-12 | 2006-02-28 | Exxonmobil Upstream Research Company | Method and system for simulating a hydrocarbon-bearing formation |
CA2383664A1 (en) | 1999-10-13 | 2001-04-19 | The Trustees Of Columbia University In The City Of New York | Petroleum reservoir simulation and characterization system and method |
US20020013687A1 (en) | 2000-03-27 | 2002-01-31 | Ortoleva Peter J. | Methods and systems for simulation-enhanced fracture detections in sedimentary basins |
GB0017227D0 (en) | 2000-07-14 | 2000-08-30 | Schlumberger Ind Ltd | Fully coupled geomechanics in a commerical reservoir simulator |
US6631202B2 (en) | 2000-12-08 | 2003-10-07 | Landmark Graphics Corporation | Method for aligning a lattice of points in response to features in a digital image |
FR2823877B1 (fr) | 2001-04-19 | 2004-12-24 | Inst Francais Du Petrole | Methode pour contraindre par des donnees dynamiques de production un modele fin representatif de la repartition dans le gisement d'une grandeur physique caracteristique de la structure du sous-sol |
US6823297B2 (en) * | 2003-03-06 | 2004-11-23 | Chevron U.S.A. Inc. | Multi-scale finite-volume method for use in subsurface flow simulation |
FR2870621B1 (fr) | 2004-05-21 | 2006-10-27 | Inst Francais Du Petrole | Methode pour generer un maillage hybride conforme en trois dimensions d'une formation heterogene traversee par une ou plusieurs discontinuites geometriques dans le but de realiser des simulations |
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US7596480B2 (en) * | 2005-04-14 | 2009-09-29 | Saudi Arabian Oil Company | Solution method and apparatus for large-scale simulation of layered formations |
FR2886742B1 (fr) | 2005-06-02 | 2007-07-27 | Inst Francais Du Petrole | Methode de changement d'echelle des permeabilites absolues pour construire un modele de simulation d'ecoulement |
EP1893845A1 (en) * | 2005-06-14 | 2008-03-05 | Services Pétroliers Schlumberger | Apparatus, method and system for improved reservoir simulation using an algebraic cascading class linear solver |
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2009
- 2009-07-01 AU AU2009266935A patent/AU2009266935B2/en active Active
- 2009-07-01 MX MX2011000115A patent/MX2011000115A/es active IP Right Grant
- 2009-07-01 BR BRPI0914102A patent/BRPI0914102A2/pt not_active IP Right Cessation
- 2009-07-01 WO PCT/US2009/049423 patent/WO2010003004A2/en active Application Filing
- 2009-07-01 CA CA2729770A patent/CA2729770C/en active Active
- 2009-07-01 US US12/496,218 patent/US8594986B2/en active Active
- 2009-07-01 EP EP09774454A patent/EP2310972A2/en not_active Withdrawn
- 2009-07-01 EA EA201170136A patent/EA201170136A1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
AU2009266935A1 (en) | 2010-01-07 |
WO2010003004A3 (en) | 2010-03-25 |
US20100004908A1 (en) | 2010-01-07 |
AU2009266935B2 (en) | 2015-08-20 |
WO2010003004A2 (en) | 2010-01-07 |
EP2310972A2 (en) | 2011-04-20 |
CA2729770A1 (en) | 2010-01-07 |
MX2011000115A (es) | 2011-04-11 |
BRPI0914102A2 (pt) | 2015-10-20 |
US8594986B2 (en) | 2013-11-26 |
CA2729770C (en) | 2016-12-13 |
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