EA201100753A1 - Композиции с пролонгированным высвобождением, содержащие производное 2-оксо-1-пирролидина - Google Patents

Композиции с пролонгированным высвобождением, содержащие производное 2-оксо-1-пирролидина

Info

Publication number
EA201100753A1
EA201100753A1 EA201100753A EA201100753A EA201100753A1 EA 201100753 A1 EA201100753 A1 EA 201100753A1 EA 201100753 A EA201100753 A EA 201100753A EA 201100753 A EA201100753 A EA 201100753A EA 201100753 A1 EA201100753 A1 EA 201100753A1
Authority
EA
Eurasian Patent Office
Prior art keywords
oxo
prolonged
compositions
pyrrolidine derivative
shipping
Prior art date
Application number
EA201100753A
Other languages
English (en)
Other versions
EA019583B1 (ru
Inventor
Доменико Фанара
Фредерик Экман
Моник Бервар
Original Assignee
Юсб Фарма, С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юсб Фарма, С.А. filed Critical Юсб Фарма, С.А.
Publication of EA201100753A1 publication Critical patent/EA201100753A1/ru
Publication of EA019583B1 publication Critical patent/EA019583B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

В заявке описана фармацевтическая композиция, включающая в качестве активного ингредиента бриварацетам или селетрацетам, а также более подробно композиция с пролонгированным высвобождением, которая получена из гранул, содержащих активный ингредиент во внутреннем ядре указанной композиции.
EA201100753A 2008-11-18 2009-11-17 Композиции с пролонгированным высвобождением, содержащие производное 2-оксо-1-пирролидина EA019583B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08105817 2008-11-18
EP09100311 2009-06-02
PCT/EP2009/065270 WO2010057869A1 (en) 2008-11-18 2009-11-17 Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivate

Publications (2)

Publication Number Publication Date
EA201100753A1 true EA201100753A1 (ru) 2012-01-30
EA019583B1 EA019583B1 (ru) 2014-04-30

Family

ID=41395028

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100753A EA019583B1 (ru) 2008-11-18 2009-11-17 Композиции с пролонгированным высвобождением, содержащие производное 2-оксо-1-пирролидина

Country Status (18)

Country Link
US (1) US8460712B2 (ru)
EP (1) EP2358361B1 (ru)
JP (2) JP5954889B2 (ru)
KR (2) KR101788804B1 (ru)
CN (2) CN104083341A (ru)
AU (1) AU2009317279B2 (ru)
BR (1) BRPI0921301A2 (ru)
CA (1) CA2741038C (ru)
DK (1) DK2358361T3 (ru)
EA (1) EA019583B1 (ru)
ES (1) ES2602606T3 (ru)
HK (1) HK1198288A1 (ru)
HU (1) HUE030963T2 (ru)
IL (1) IL212271A (ru)
MX (1) MX356281B (ru)
PL (1) PL2358361T3 (ru)
PT (1) PT2358361T (ru)
WO (1) WO2010057869A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2358360T3 (en) * 2008-11-18 2016-12-12 Ucb Biopharma Sprl EXTENDED release formulations comprising one 2-OXO-1 PYRROLIDIN DERIVATIVE
JP6902033B2 (ja) 2015-12-30 2021-07-14 アダマス ファーマシューティカルズ， インコーポレイテッド 発作−関連障害の処置のための方法および組成物
WO2017195144A1 (en) * 2016-05-12 2017-11-16 Jubilant Generics Limited Pharmaceutical compositions comprising brivaracetam
CN115721624A (zh) * 2021-08-25 2023-03-03 北京海美源医药科技有限公司 一种布立西坦药物组合物及其制备方法和其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004297D0 (en) * 2000-02-23 2000-04-12 Ucb Sa 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
ZA200707250B (en) * 2005-01-27 2009-06-24 Alembic Ltd Extended release formulation of levetiracetam
US20070298098A1 (en) 2005-02-16 2007-12-27 Elan Pharma International Limited Controlled Release Compositions Comprising Levetiracetam
WO2006088864A1 (en) * 2005-02-16 2006-08-24 Elan Pharma International Limited Controlled release compositions comprising levetiracetam
EP1909770B1 (en) 2005-02-22 2013-03-20 Sun Pharmaceutical Industries Limited Oral controlled release composition containing levetiracetam
CN101111230B (zh) * 2005-03-29 2010-05-19 赢创罗姆有限责任公司 包含对活性成分具有调节释放作用的小丸的多颗粒药用形式
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
ES2444009T3 (es) * 2006-06-08 2014-02-21 Ucb Pharma, S.A. Co-cristales de pirrolidinonas
MX370905B (es) * 2006-08-31 2020-01-09 Adare Pharmaceuticals Inc Sistema de distribucion de farmacos, que comprenden soluciones solidas de farmacos debilmente basicos.
WO2008062446A2 (en) * 2006-09-14 2008-05-29 Alembic Limited An extended release composition of levetiracetam, which exhibits no adverse food effect
US9555006B2 (en) * 2007-09-21 2017-01-31 Evonik Roehm Gmbh PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
PL2273975T3 (pl) * 2008-03-03 2014-09-30 Ucb Pharma Sa Roztwory farmaceutyczne, sposoby wytwarzania i zastosowania terapeutyczne

Also Published As

Publication number Publication date
KR20170007528A (ko) 2017-01-18
EP2358361B1 (en) 2016-09-14
US8460712B2 (en) 2013-06-11
HUE030963T2 (en) 2017-06-28
IL212271A0 (en) 2011-06-30
AU2009317279B2 (en) 2013-10-24
EP2358361A1 (en) 2011-08-24
IL212271A (en) 2016-10-31
MX2011004572A (es) 2011-06-17
CN104083341A (zh) 2014-10-08
PT2358361T (pt) 2016-11-18
BRPI0921301A2 (pt) 2015-12-29
EA019583B1 (ru) 2014-04-30
CA2741038A1 (en) 2010-05-27
AU2009317279A1 (en) 2010-05-27
HK1198288A1 (en) 2015-03-27
WO2010057869A1 (en) 2010-05-27
JP2015143256A (ja) 2015-08-06
JP2012509356A (ja) 2012-04-19
CA2741038C (en) 2015-01-13
KR101788804B1 (ko) 2017-10-20
US20110274762A1 (en) 2011-11-10
CN102215828A (zh) 2011-10-12
DK2358361T3 (en) 2016-12-12
MX356281B (es) 2018-05-22
KR20110089184A (ko) 2011-08-04
ES2602606T3 (es) 2017-02-21
JP5954889B2 (ja) 2016-07-20
PL2358361T3 (pl) 2017-02-28

Similar Documents

Publication Publication Date Title
WO2008006528A3 (en) Pharmaceutical compositions comprising levetiracetam
UA112281C2 (uk) Стабільні інсектицидні композиції і способи їх отримання
WO2009100441A3 (en) Depot formulations
WO2009117130A3 (en) Extended release forumulation containing a wax
WO2010052161A3 (en) Herbicidal compositions
EA201100752A1 (ru) Фармацевтические пероральные композиции с пролонгированным высвобождением, включающие производные 2-оксо-1-пирролидина
DE602006002260D1 (de) Insektenabweisende zusammensetzungen mit verzögerter freisetzung
WO2009039951A3 (de) Wirkstoffkombinationen mit insektiziden und akariziden eigenschaften
EA201101116A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
BR112012029517A2 (pt) formulações de fragrância, métodos de fabricação e artigos compreendendo as mesmas.
BRPI0914682B8 (pt) compostos de heteroarila e composições compreendendo os referidos compostos
BRPI0923728A2 (pt) "método de preparação de compostos de di-hidroindeno amida, suas composições farmacêuticas contendo esses compostos e uso como inibidor de proteína quinase".
GT200800276A (es) Composiciones farmaceuticas estabilizadas que comprenden fesoterodina
EA201000089A1 (ru) Применение гомо- и сополимеров для стабилизации составов активных ингредиентов
UY31788A (es) Formulación farmacéutica sólida con liberación retardada
EA201101118A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
EA200970532A1 (ru) Фумаратная соль (альфа s, бета r)-6-бром-альфа-[2-(диметиламино)этил]-2-метокси-альфа-1-нафталенил-бета-фенил-3-хинолинэтанола
PT2076119E (pt) Composição solvente incluindo pelo menos dois solventes, e formulação fitossanitária que inclua a composição referida bem como um composto activo
MA32979B1 (fr) Derives aminoesterifies d'alcaloides et composition medicinale les incluant
ES2465478T8 (es) Composiciones farmacéuticas que comprenden brivaracetam
EA201590805A1 (ru) Композиция с немедленным и пролонгированным высвобождением
EP2266626A4 (en) COMPOSITION FOR TOPICAL APPLICATION WITH A TRANSCRIPTION FACTOR DECOY AS AN ACTIVE SUBSTANCE
EA201300493A1 (ru) Гербицидная композиция
BR112012009310B8 (pt) composto derivados de 2-oxo-1-pirrolidinil imidazotiadiazol, uso dos mesmos e composição farmacêutica compreendendo os mesmos
UY31128A1 (es) Formulacion de nevirapina de liberacion prolongada