EA200700130A1 - Композиции, содержащие стронций и витамин d, и их применение - Google Patents

Композиции, содержащие стронций и витамин d, и их применение

Info

Publication number
EA200700130A1
EA200700130A1 EA200700130A EA200700130A EA200700130A1 EA 200700130 A1 EA200700130 A1 EA 200700130A1 EA 200700130 A EA200700130 A EA 200700130A EA 200700130 A EA200700130 A EA 200700130A EA 200700130 A1 EA200700130 A1 EA 200700130A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vitamin
stronties
application
compositions containing
strontium
Prior art date
Application number
EA200700130A
Other languages
English (en)
Other versions
EA011814B1 (ru
Inventor
Йохн Николай Хварре Кристенсен
Original Assignee
Стронтин Апс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34972075&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200700130(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Стронтин Апс filed Critical Стронтин Апс
Publication of EA200700130A1 publication Critical patent/EA200700130A1/ru
Publication of EA011814B1 publication Critical patent/EA011814B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к обнаружению факта, что очень благоприятные фармакокинетические характеристики получают при комбинировании двух солей стронция в одной фармацевтической композиции. В одном из аспектов данное изобретение относится к фармацевтической композиции, содержащей по меньшей мере две соли стронция, для применения в качестве лекарственного средства и, в частности, для лечения и предупреждения болезней костей, таких как остеопороз. Композиция предпочтительно содержит карбонат стронция и хлориды стронция. Кроме того, композиция может содержать соединение витамина D, предпочтительно витамин D.
EA200700130A 2004-06-25 2005-06-24 Композиции, содержащие стронций и витамин d, и их применение EA011814B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200400991 2004-06-25
DKPA200401733 2004-11-10
PCT/DK2005/000425 WO2006000224A2 (en) 2004-06-25 2005-06-24 Compositions comprising strontium and vitamin d and uses thereof

Publications (2)

Publication Number Publication Date
EA200700130A1 true EA200700130A1 (ru) 2007-06-29
EA011814B1 EA011814B1 (ru) 2009-06-30

Family

ID=34972075

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700130A EA011814B1 (ru) 2004-06-25 2005-06-24 Композиции, содержащие стронций и витамин d, и их применение

Country Status (16)

Country Link
US (1) US8658206B2 (ru)
EP (1) EP1768748B2 (ru)
JP (2) JP5070046B2 (ru)
KR (1) KR20070034075A (ru)
AT (1) ATE443541T1 (ru)
AU (1) AU2005256317B2 (ru)
BR (1) BRPI0512357A (ru)
CA (1) CA2571449C (ru)
DE (1) DE602005016803D1 (ru)
DK (1) DK1768748T4 (ru)
EA (1) EA011814B1 (ru)
HK (1) HK1102427A1 (ru)
IL (1) IL180144A0 (ru)
MX (1) MXPA06015187A (ru)
NO (1) NO20070206L (ru)
WO (1) WO2006000224A2 (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080118603A1 (en) * 2006-11-21 2008-05-22 Lada Mark W Nutritional beverage for optimal bone health
PL2097137T3 (pl) * 2006-11-21 2013-02-28 Mokwalo Spf S A Kompozycje zawierające stront i ich zastosowanie w leczeniu lub zapobieganiu zapaleniu dziąseł, zapaleniu przyzębia, zapaleniu przyzębia będącemu manifestacją chorób układowych i martwiczym chorobom przyzębia
JP5907656B2 (ja) * 2007-04-23 2016-04-26 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ ストロンチウム化合物を含むフィブリン組成物
JP2010533667A (ja) * 2007-07-19 2010-10-28 ディーエスエム アイピー アセッツ ビー．ブイ． 錠剤化可能な親油性健康成分の配合物
CA2695504C (en) * 2007-08-03 2017-05-30 Nucitec S.A. De C.V. Compositions and methods for treatment and prevention of osteoarthritis
EP2416756A2 (en) * 2009-04-10 2012-02-15 Mahmut Bilgic Stable pharmaceutical compositions with high bioavailibility
FR2945748A1 (fr) * 2009-05-20 2010-11-26 Debregeas Et Associes Pharma Medicament a base de calcium et de vitamine d.
FR2953139B1 (fr) * 2009-11-27 2012-04-13 Servier Lab Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine
WO2012006473A1 (en) 2010-07-07 2012-01-12 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP2591354B1 (en) * 2010-07-07 2016-09-07 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
WO2012006474A2 (en) 2010-07-07 2012-01-12 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP2590656B1 (en) 2010-07-07 2017-11-15 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
JP5827328B2 (ja) 2010-07-07 2015-12-02 アーデリクス，インコーポレーテッド リン酸輸送を阻害する化合物及び方法
AU2012212385B2 (en) * 2011-02-02 2015-01-15 Ent Technologies Pty Ltd Compositions and methods for the treatment of nasal passages
EP2530068A1 (en) 2011-05-31 2012-12-05 Lacer, S.A. New strontium salts, synthesis and use thereof in the treatment of osteoporosis
WO2014044756A1 (en) * 2012-09-20 2014-03-27 Mokwalo SA Strontium as anti microbial compound

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3345265A (en) * 1963-10-09 1967-10-03 Kendall & Co Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating
US3699221A (en) * 1965-02-23 1972-10-17 Murray L Schole Dental preparations
US3988434A (en) 1972-08-07 1976-10-26 Schole Murray L Dental preparation
FR2633619B1 (fr) 1988-06-29 1991-02-08 Adir Nouveau sel de strontium, son procede de preparation et les compositions pharmaceutiques le renfermant
FR2651497B1 (fr) 1989-09-01 1991-10-25 Adir Nouveaux sels de metaux bivalents de l'acide n, n-di (carboxymethyl)amino-2 cyano-3 carboxymethyl-4 carboxy-5 thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2658816A1 (fr) * 1990-02-27 1991-08-30 Adir Nouveaux sels de metaux alcalinoterreux d'oxa-polyacides leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5380530A (en) 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
US5624906A (en) * 1994-12-08 1997-04-29 Lever Brothers Company, Division Of Conopco, Inc. Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds
FR2749759B1 (fr) 1996-06-17 1999-11-26 Adir Utilisation de sels de strontium pour l'obtention de compositions pharmaceutiques destinees au traitement de l'arthrose
CN1164603C (zh) 2001-09-29 2004-09-01 南京化工大学 1，6－二磷酸果糖锶盐系列化合物及其制备方法和在医药中的应用
FR2844797B1 (fr) 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel des tetraesters de l'acide 5-[bis (carboxymethyl)]-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2844796A1 (fr) 2002-09-24 2004-03-26 Servier Lab Nouveau procede de synthese industrielle du diester methylique de l'acide 5-amino-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2844795B1 (fr) 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel du ranelate de strontium et de ses hydrates
PL1534305T3 (pl) 2003-05-07 2007-03-30 Osteologix As Leczenie zaburzeń chrząstek i kości solami strontu rozpuszczalnymi w wodzie
CA2524610C (en) 2003-05-07 2014-03-25 Osteologix A/S Strontium combinations for prophylaxis/treatment of cartilage and/or bone conditions
EP1622629B1 (en) * 2003-05-07 2013-07-10 Osteologix A/S Controlled-release composition containing a strontium salt

Also Published As

Publication number Publication date
DE602005016803D1 (de) 2009-11-05
DK1768748T3 (da) 2010-02-01
BRPI0512357A (pt) 2008-03-04
IL180144A0 (en) 2007-06-03
WO2006000224A2 (en) 2006-01-05
EP1768748A2 (en) 2007-04-04
JP2012193208A (ja) 2012-10-11
JP2008503504A (ja) 2008-02-07
EP1768748B1 (en) 2009-09-23
DK1768748T4 (da) 2019-06-11
KR20070034075A (ko) 2007-03-27
WO2006000224A3 (en) 2006-05-18
CA2571449C (en) 2015-12-08
EA011814B1 (ru) 2009-06-30
NO20070206L (no) 2007-03-22
JP5070046B2 (ja) 2012-11-07
AU2005256317A1 (en) 2006-01-05
US20080026037A1 (en) 2008-01-31
EP1768748B2 (en) 2019-03-13
US8658206B2 (en) 2014-02-25
AU2005256317B2 (en) 2011-09-15
MXPA06015187A (es) 2007-09-27
HK1102427A1 (en) 2007-11-23
CA2571449A1 (en) 2006-01-05
ATE443541T1 (de) 2009-10-15

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): AM AZ BY KG MD TJ TM

PC4A Registration of transfer of a eurasian patent by assignment