EA200601559A1 - Детектирование вируса папилломы человека - Google Patents

Детектирование вируса папилломы человека

Info

Publication number
EA200601559A1
EA200601559A1 EA200601559A EA200601559A EA200601559A1 EA 200601559 A1 EA200601559 A1 EA 200601559A1 EA 200601559 A EA200601559 A EA 200601559A EA 200601559 A EA200601559 A EA 200601559A EA 200601559 A1 EA200601559 A1 EA 200601559A1
Authority
EA
Eurasian Patent Office
Prior art keywords
screening
persistent
detection
loss
papilloma virus
Prior art date
Application number
EA200601559A
Other languages
English (en)
Other versions
EA010500B1 (ru
Inventor
Франк Карльсен
Original Assignee
Норчип А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32050932&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200601559(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Норчип А/С filed Critical Норчип А/С
Publication of EA200601559A1 publication Critical patent/EA200601559A1/ru
Publication of EA010500B1 publication Critical patent/EA010500B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Настоящее изобретение относится к in vitro способам скрининга человека на предмет наличия вируса папилломы человека (HPV) с дефектом регуляции экспрессии мРНК Е6/Е7 и сниженной репликацией и/или экспрессией стабилизированного пре-мРНК, кодирующей полноразмерный белок Е6. В частности, в данном изобретении предлагаются in vitro способы скрининга хронических клеточных нарушений или хронических поражений CIN III, раковой опухоли in situ или сквамозных внутриэпителиальных поражений с высокой степенью злокачественности (HSIL). Данные способы можно использовать для скрининга рака шейки матки.
EA200601559A 2004-02-26 2005-02-28 Детектирование вируса папилломы человека EA010500B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0404315.4A GB0404315D0 (en) 2004-02-26 2004-02-26 Improved detection of human papillomavirus
PCT/GB2005/000774 WO2005083129A1 (en) 2004-02-26 2005-02-28 Detection of human papillomavirus

Publications (2)

Publication Number Publication Date
EA200601559A1 true EA200601559A1 (ru) 2007-02-27
EA010500B1 EA010500B1 (ru) 2008-10-30

Family

ID=32050932

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601559A EA010500B1 (ru) 2004-02-26 2005-02-28 Детектирование вируса папилломы человека

Country Status (16)

Country Link
US (2) US20070292841A1 (ru)
EP (1) EP1718774B1 (ru)
JP (1) JP2007524421A (ru)
CN (1) CN1946858A (ru)
AT (1) ATE545715T1 (ru)
AU (2) AU2005216414A1 (ru)
CA (1) CA2557519A1 (ru)
DK (1) DK1718774T3 (ru)
EA (1) EA010500B1 (ru)
GB (1) GB0404315D0 (ru)
HK (1) HK1090956A1 (ru)
IL (1) IL177705A0 (ru)
MX (1) MXPA06009644A (ru)
NZ (1) NZ549456A (ru)
WO (1) WO2005083129A1 (ru)
ZA (1) ZA200607103B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003057914A2 (en) * 2002-01-07 2003-07-17 Norchip A/S METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA
GB0404315D0 (en) * 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus
WO2008071998A2 (en) * 2006-12-15 2008-06-19 Oncomethylome Sciences Sa Diagnostic methods for diseases caused by a hpv infection comprising determining the methylation status of the hpv genome
US20110275698A1 (en) * 2010-05-10 2011-11-10 Norchip A/S "test and treat" strategy for treating transforming hpv infection
CN103476948A (zh) * 2011-01-28 2013-12-25 领先细胞医疗诊断有限公司 用于测定头颈癌和宫颈病变中的hpv状态的rnascope* hpv测定法
US20140357509A1 (en) * 2013-03-28 2014-12-04 Advanced Cell Diagnostics, Inc. Differentiation between transient and persistent high-risk hpv infection by in situ hybridization
WO2014157337A1 (ja) * 2013-03-29 2014-10-02 堺化学工業株式会社 応力発光材料とその応用、応力発光材料用原料組成物、及び、応力発光材料の製造方法
WO2014201138A1 (en) * 2013-06-11 2014-12-18 Stelling James R Method for detection of fetal abnormalities
GB201310933D0 (en) 2013-06-19 2013-07-31 Norchip As A method of cervical screening
CN106048014B (zh) * 2016-06-07 2019-12-10 博奥生物集团有限公司 一种用于实时检测nasba产物的高特异探针
WO2018059581A1 (zh) * 2016-09-30 2018-04-05 广州易活生物科技有限公司 一种基于efirm技术的hpv病毒分型检测的探针、试剂盒及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639871A (en) * 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
US5506105A (en) * 1991-12-10 1996-04-09 Dade International Inc. In situ assay of amplified intracellular mRNA targets
US6174668B1 (en) * 1993-05-14 2001-01-16 Johnson & Johnson Clinical Diagnostics, Inc. Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures
DE19506561C1 (de) * 1995-02-24 1996-10-10 Deutsches Krebsforsch Verfahren zur Früherkennung von HPV-assoziierten Karzinomen bzw. von hochgradigen, durch HPV-verursachten Dysplasien
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
WO2003057914A2 (en) * 2002-01-07 2003-07-17 Norchip A/S METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA
GB0404315D0 (en) * 2004-02-26 2004-03-31 Norchip As Improved detection of human papillomavirus

Also Published As

Publication number Publication date
MXPA06009644A (es) 2007-03-21
HK1090956A1 (en) 2007-01-05
NZ549456A (en) 2009-02-28
EA010500B1 (ru) 2008-10-30
WO2005083129A1 (en) 2005-09-09
US20100330550A1 (en) 2010-12-30
US20070292841A1 (en) 2007-12-20
AU2005216414A1 (en) 2005-09-09
AU2010200955B2 (en) 2012-05-17
GB0404315D0 (en) 2004-03-31
DK1718774T3 (da) 2012-05-14
CA2557519A1 (en) 2005-09-09
AU2010200955A1 (en) 2010-04-01
WO2005083129A8 (en) 2006-10-26
IL177705A0 (en) 2006-12-31
ATE545715T1 (de) 2012-03-15
CN1946858A (zh) 2007-04-11
JP2007524421A (ja) 2007-08-30
ZA200607103B (en) 2008-07-30
EP1718774B1 (en) 2012-02-15
EP1718774A1 (en) 2006-11-08

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU