EA200401071A1 - Пероральная лекарственная форма для контролируемого высвобождения лекарственного средства - Google Patents

Пероральная лекарственная форма для контролируемого высвобождения лекарственного средства

Info

Publication number
EA200401071A1
EA200401071A1 EA200401071A EA200401071A EA200401071A1 EA 200401071 A1 EA200401071 A1 EA 200401071A1 EA 200401071 A EA200401071 A EA 200401071A EA 200401071 A EA200401071 A EA 200401071A EA 200401071 A1 EA200401071 A1 EA 200401071A1
Authority
EA
Eurasian Patent Office
Prior art keywords
core
dosage form
coating
eroding
medicines
Prior art date
Application number
EA200401071A
Other languages
English (en)
Other versions
EA008286B1 (ru
Inventor
Луиджи Мартини
Винченцо Ре
Чи Леунг Ли
Хелен Энн Вилли
Original Assignee
Глэксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0203297A external-priority patent/GB0203297D0/en
Priority claimed from GBGB0203296.9A external-priority patent/GB0203296D0/en
Priority claimed from GB0203298A external-priority patent/GB0203298D0/en
Application filed by Глэксо Груп Лимитед filed Critical Глэксо Груп Лимитед
Publication of EA200401071A1 publication Critical patent/EA200401071A1/ru
Publication of EA008286B1 publication Critical patent/EA008286B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Пероральная лекарственная форма, включающая (а) эродирующее ядро, содержащее фармацевтически активное слабое основание или его фармацевтически приемлемую соль или сольват; и (б) эродирующее покрытие, окружающее указанное ядро, причем покрытие включает одно или более отверстий, проходящих, по существу, полностью сквозь указанное покрытие, но не проникающих в указанное ядро и соединяющих среду использования с указанным ядром; отличающаяся тем, что высвобождение фармацевтически активного слабого основания или его фармацевтически приемлемой соли или сольвата из дозированной лекарственной формы происходит через указанное(ые) отверстие(я) путем эрозии указанного эродирующего ядра и посредством эрозии указанного эродирующего покрытия при заранее определенных значениях рН; способ получения такой дозированной лекарственной формы и использование такой дозированной лекарственной формы в медицине.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401071A 2002-02-12 2003-02-12 Пероральная лекарственная форма для контролируемого высвобождения лекарственного средства EA008286B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0203297A GB0203297D0 (en) 2002-02-12 2002-02-12 Novel composition
GBGB0203296.9A GB0203296D0 (en) 2002-02-12 2002-02-12 Novel composition
GB0203298A GB0203298D0 (en) 2002-02-12 2002-02-12 Novel composition
PCT/GB2003/000594 WO2003068195A1 (en) 2002-02-12 2003-02-12 Oral dosage form for controlled drug release

Publications (2)

Publication Number Publication Date
EA200401071A1 true EA200401071A1 (ru) 2004-12-30
EA008286B1 EA008286B1 (ru) 2007-04-27

Family

ID=27738830

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401071A EA008286B1 (ru) 2002-02-12 2003-02-12 Пероральная лекарственная форма для контролируемого высвобождения лекарственного средства

Country Status (34)

Country Link
EP (1) EP1474114B1 (ru)
JP (2) JP2005526031A (ru)
KR (2) KR101048925B1 (ru)
CN (1) CN100444833C (ru)
AP (1) AP1736A (ru)
AR (1) AR038417A1 (ru)
AT (1) ATE455540T1 (ru)
AU (1) AU2003245763B2 (ru)
BR (1) BRPI0307319B8 (ru)
CA (1) CA2475544A1 (ru)
CL (1) CL2007003010A1 (ru)
CO (1) CO5601025A2 (ru)
CY (1) CY1109939T1 (ru)
DE (1) DE60331041D1 (ru)
DK (1) DK1474114T3 (ru)
EA (1) EA008286B1 (ru)
EC (1) ECSP045232A (ru)
ES (1) ES2336319T3 (ru)
HK (1) HK1072194A1 (ru)
IL (1) IL163098A (ru)
IS (1) IS2747B (ru)
MA (1) MA27689A1 (ru)
MX (1) MXPA04007794A (ru)
MY (1) MY139719A (ru)
NO (1) NO334453B1 (ru)
NZ (1) NZ534152A (ru)
OA (1) OA12770A (ru)
PE (1) PE20030800A1 (ru)
PL (1) PL206596B1 (ru)
PT (1) PT1474114E (ru)
SI (1) SI1474114T1 (ru)
TW (1) TWI286079B (ru)
UY (1) UY27660A1 (ru)
WO (1) WO2003068195A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0120835D0 (en) 2001-08-28 2001-10-17 Smithkline Beecham Plc Process
GB0203296D0 (en) 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
AR045330A1 (es) * 2003-08-07 2005-10-26 Sb Pharmco Inc Forma de dosificacion oral, procedimiento para su preparacion y uso del compuesto 5-(4-(2-(n-metil-n- (2-piridil)amino)etoxi )bencil) tiazolidin-2,4-diona o una sal o solvato farmaceuticamente aceptable del mismo para prepararla
GB0318824D0 (en) * 2003-08-11 2003-09-10 Glaxo Group Ltd Novel composition
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
WO2007090091A2 (en) * 2006-01-27 2007-08-09 Eurand, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CN101410094B (zh) * 2006-01-27 2013-04-17 阿普塔利斯制药股份有限公司 包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送系统

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2150830B (en) * 1983-12-05 1987-08-19 Alza Corp Drug dispenser
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
AR023699A1 (es) * 1998-11-12 2002-09-04 Smithkline Beecham Corp Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica
WO2000028989A1 (en) * 1998-11-12 2000-05-25 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
GB0027471D0 (en) * 2000-11-08 2000-12-27 Smithkline Beecham Plc Processes

Also Published As

Publication number Publication date
TW200307567A (en) 2003-12-16
KR20040084900A (ko) 2004-10-06
JP5279757B2 (ja) 2013-09-04
AP2004003087A0 (en) 2004-09-30
OA12770A (en) 2006-07-04
EP1474114A1 (en) 2004-11-10
AP1736A (en) 2007-05-02
AU2003245763B2 (en) 2008-12-11
HK1072194A1 (en) 2005-08-19
JP2005526031A (ja) 2005-09-02
EA008286B1 (ru) 2007-04-27
AU2003245763A1 (en) 2003-09-04
UY27660A1 (es) 2003-09-30
CN1655768A (zh) 2005-08-17
IL163098A (en) 2009-05-04
DK1474114T3 (da) 2010-04-12
CA2475544A1 (en) 2003-08-21
PL206596B1 (pl) 2010-08-31
SI1474114T1 (sl) 2010-04-30
ES2336319T3 (es) 2010-04-12
CO5601025A2 (es) 2006-01-31
NO334453B1 (no) 2014-03-03
KR20100086084A (ko) 2010-07-29
CL2007003010A1 (es) 2008-01-25
MA27689A1 (fr) 2006-01-02
CY1109939T1 (el) 2014-09-10
NO20043633L (no) 2004-10-27
WO2003068195A1 (en) 2003-08-21
IS2747B (is) 2011-08-15
IS7383A (is) 2004-08-05
ECSP045232A (es) 2004-09-28
NZ534152A (en) 2006-11-30
EP1474114B1 (en) 2010-01-20
CN100444833C (zh) 2008-12-24
PE20030800A1 (es) 2003-10-31
JP2010159301A (ja) 2010-07-22
PL371368A1 (en) 2005-06-13
MY139719A (en) 2009-10-30
AR038417A1 (es) 2005-01-12
KR101048925B1 (ko) 2011-07-12
MXPA04007794A (es) 2004-10-15
PT1474114E (pt) 2010-03-04
TWI286079B (en) 2007-09-01
DE60331041D1 (de) 2010-03-11
BR0307319A (pt) 2005-01-04
BRPI0307319B8 (pt) 2021-05-25
ATE455540T1 (de) 2010-02-15
BRPI0307319B1 (pt) 2018-05-02

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM KG TM