EA200400807A1 - COMPOSITION FOR THE TREATMENT OF NEURAL TERRIBROVASCULAR DISTURBANCES - Google Patents

COMPOSITION FOR THE TREATMENT OF NEURAL TERRIBROVASCULAR DISTURBANCES

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Publication number
EA200400807A1
EA200400807A1 EA200400807A EA200400807A EA200400807A1 EA 200400807 A1 EA200400807 A1 EA 200400807A1 EA 200400807 A EA200400807 A EA 200400807A EA 200400807 A EA200400807 A EA 200400807A EA 200400807 A1 EA200400807 A1 EA 200400807A1
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EA
Eurasian Patent Office
Prior art keywords
composition
fraction
terribrovascular
disturbances
neural
Prior art date
Application number
EA200400807A
Other languages
Russian (ru)
Other versions
EA007067B1 (en
Inventor
Мадхур Рей
Рагхвендра Пал
Сатиаван Сингх
Нанду Мал Кханна
Original Assignee
Каунсил Оф Сайентифик Энд Индастриал Рисерч
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Каунсил Оф Сайентифик Энд Индастриал Рисерч filed Critical Каунсил Оф Сайентифик Энд Индастриал Рисерч
Publication of EA200400807A1 publication Critical patent/EA200400807A1/en
Publication of EA007067B1 publication Critical patent/EA007067B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)

Abstract

Данное изобретение относится к композиции, полученной из растворимого липидного экстракта корневищ и листьев видов Curcuma семейства Zingiberaceae, используемой для лечения нейроцереброваскулярных нарушений, указанная композиция содержит фракцию A, состоящую из ar-турмерона формулы (1) и турмерона формулы (2), и/или вместе с фракцией B, состоящей из куркумена и зингиберина, и/или фракцией C, состоящей из гермакрона, куркумерона, зедоарона, седоарондиола, изоздедоаронидиола, куркуменона и курлона, и/или фармацевтически приемлемые добавки, и к способу лечения нейроцереброваскулярных нарушений у животных, включая человека, с использованием указанной композиции, введением терапевтически эффективного количества растворимого липидного экстракта.Отчет о международном поиске был опубликован 2004.06.17.This invention relates to a composition obtained from a soluble lipid extract of rhizomes and leaves of Curcuma species of the Zingiberaceae family, used to treat neurocerebrovascular disorders, said composition comprising fraction A consisting of ar-turmerone of formula (1) and turmerone of formula (2), and / or together with fraction B, consisting of curcumin and zingiberin, and / or fraction C, consisting of germacron, curcumerone, zedoarone, seroarondiol, isodedoaronidiol, curcumenon and curlon, and / or pharmaceutically acceptable additives, and to the method neurocerebrovascular disorders in animals, including humans, using this composition, by administering a therapeutically effective amount of a soluble lipid extract. The international search report was published 2004.06.17.

EA200400807A 2001-12-14 2002-12-14 Composition for treating of neurocerebrovascular disorders EA007067B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34016501P 2001-12-14 2001-12-14
PCT/IB2002/005366 WO2003051380A2 (en) 2001-12-14 2002-12-14 Compositions containeing curcuma extracts for the treatment of neurocerebrovascular disorders

Publications (2)

Publication Number Publication Date
EA200400807A1 true EA200400807A1 (en) 2004-12-30
EA007067B1 EA007067B1 (en) 2006-06-30

Family

ID=23332163

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400807A EA007067B1 (en) 2001-12-14 2002-12-14 Composition for treating of neurocerebrovascular disorders

Country Status (19)

Country Link
US (2) US20060051438A1 (en)
EP (1) EP1453528B1 (en)
JP (1) JP4695839B2 (en)
KR (1) KR101001815B1 (en)
CN (1) CN100528149C (en)
AU (2) AU2002348802A1 (en)
BR (1) BR0214962A (en)
CA (1) CA2473874C (en)
DE (1) DE60233069D1 (en)
EA (1) EA007067B1 (en)
EE (1) EE05374B1 (en)
GE (1) GEP20084442B (en)
LT (1) LT5284B (en)
LV (1) LV13250B (en)
MX (1) MXPA04005680A (en)
NO (1) NO332066B1 (en)
UA (1) UA82057C2 (en)
WO (1) WO2003051380A2 (en)
ZA (1) ZA200404648B (en)

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US9492402B2 (en) 2005-05-30 2016-11-15 Benny Antony Formulation of curcuminoids with enhanced bioavailability of curcumin, demethoxycurcumin, bisdemethoxycurcumin and method of preparation and uses thereof
US10543277B2 (en) 2005-05-30 2020-01-28 Arjuna Natural Private Limited Formulation of curcumin with enhanced bioavailability of curcumin and method of preparation and treatment thereof
US8859020B2 (en) 2005-05-30 2014-10-14 Benny Antony Treatment of alzheimer's with a curcuminoid mixture and essential oil of turmeric having 45% Ar-turmerone
PT1890546T (en) 2005-05-30 2019-01-23 Antony Benny Method for improving the bioavailability of curcumin
US10286027B2 (en) 2005-05-30 2019-05-14 Arjuna Natural Extracts, Ltd. Sustained release formulations of curcuminoids and method of preparation thereof
US7883728B2 (en) 2005-05-30 2011-02-08 Arjuna Natural Extracts, Ltd. Composition to enhance the bioavailability of curcumin
JP4980626B2 (en) * 2006-02-28 2012-07-18 ポーラ化成工業株式会社 Plasminogen activator inhibitor I inhibitor and food composition comprising the same
JP5207341B2 (en) * 2006-10-26 2013-06-12 独立行政法人産業技術総合研究所 Inflammatory cytokine production inhibitor
EP2205255B8 (en) * 2007-10-03 2015-09-30 Sabell Corporation Herbal compositions and methods for treating hepatic disorders
WO2010099985A2 (en) * 2009-03-05 2010-09-10 Keygene N.V. Plant volatiles based on r-curcumene
AU2010278711A1 (en) 2009-07-31 2012-02-23 Cognition Therapeutics, Inc. Inhibitors of cognitive decline
JP5764288B2 (en) * 2009-09-24 2015-08-19 ハウス食品グループ本社株式会社 A composition containing a turmeric extract and a gadget extract
JP5578822B2 (en) * 2009-09-25 2014-08-27 株式会社ピカソ美化学研究所 Acetylcholinesterase inhibitor
CN103458885B (en) 2011-02-02 2016-02-10 考格尼申治疗股份有限公司 The compound be separated by turmeric oil and using method
BR112013023705B8 (en) 2011-03-29 2020-01-28 Council Scient Ind Res process for the modification of aromatic turmeric essential oil
GB201111319D0 (en) 2011-07-04 2011-08-17 Univ Leuven Kath Anticonvulsant activity of tumeric oil and bisabolene sesquiterpenoids of curcuma longa
KR101637375B1 (en) * 2012-01-13 2016-07-07 주식회사 엘지생활건강 Composition for improving skin wrinkle and enhancing elasticity
CN102697757B (en) * 2012-05-18 2014-06-04 广州军区广州总医院 Application of p-hydroxy benzylidene acetone in preparation of drugs for preventing and/or treating encephalopathy
JP2014201528A (en) * 2013-04-02 2014-10-27 クラシエ製薬株式会社 Antioxidant
ES2915833T3 (en) 2014-01-31 2022-06-27 Cognition Therapeutics Inc Isoindoline compositions and methods for treating neurodegenerative disease and macular degeneration
CN104840451B (en) * 2014-09-23 2017-04-05 桂林八加一药业股份有限公司 It is a kind of for treating coronary heart disease, the effective ingredient in Chinese of hyperlipidemia, preparation method and the therefrom method of separating effective ingredient
CN105738546B (en) * 2014-12-12 2020-01-21 桂林八加一药业股份有限公司 Method for establishing fingerprint of radix curcumae medicinal material and fingerprint thereof
CN105055449B (en) * 2015-07-27 2019-08-09 中国科学院西北高原生物研究所 A kind of Sailongbone extracts with anti-inflammatory and antalgic activity, preparation method and Chinese materia medica preparation
CN106491996A (en) * 2016-12-29 2017-03-15 王明金 A kind of treat Chinese medicine composition of manic disorder and preparation method thereof
CN106491997A (en) * 2016-12-29 2017-03-15 王明金 A kind of Chinese medicine composition of anti-mental disorder and preparation method thereof
CN106492137A (en) * 2016-12-29 2017-03-15 王明金 A kind of treat Chinese medicine composition of depression and preparation method thereof
CN106511784A (en) * 2016-12-29 2017-03-22 王明金 Traditional Chinese medicine composition for treating mental diseases and preparation method thereof
CN110621309A (en) * 2017-05-12 2019-12-27 好侍健康食品株式会社 Anti-inflammatory composition
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Also Published As

Publication number Publication date
AU2009212969B2 (en) 2011-06-02
LV13250B (en) 2006-02-20
KR20040073478A (en) 2004-08-19
MXPA04005680A (en) 2004-10-15
EP1453528A2 (en) 2004-09-08
CN1615144A (en) 2005-05-11
GEP20084442B (en) 2008-08-10
DE60233069D1 (en) 2009-09-03
WO2003051380A3 (en) 2004-06-17
EE200400097A (en) 2004-10-15
LT2004060A (en) 2005-06-27
EP1453528B1 (en) 2009-07-22
KR101001815B1 (en) 2010-12-15
CN100528149C (en) 2009-08-19
JP4695839B2 (en) 2011-06-08
LT5284B (en) 2005-11-25
US20060051438A1 (en) 2006-03-09
EE05374B1 (en) 2011-02-15
CA2473874A1 (en) 2003-06-26
NO20043000L (en) 2004-07-13
BR0214962A (en) 2004-12-14
US20100093870A1 (en) 2010-04-15
EA007067B1 (en) 2006-06-30
UA82057C2 (en) 2008-03-11
WO2003051380A2 (en) 2003-06-26
NO332066B1 (en) 2012-06-18
CA2473874C (en) 2011-11-22
AU2002348802A1 (en) 2003-06-30
AU2009212969A1 (en) 2009-10-01
JP2005516930A (en) 2005-06-09
ZA200404648B (en) 2005-11-30

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