EA200301080A1 - Терапевтический агент для лечения гиперфункции мочевого пузыря - Google Patents

Терапевтический агент для лечения гиперфункции мочевого пузыря

Info

Publication number
EA200301080A1
EA200301080A1 EA200301080A EA200301080A EA200301080A1 EA 200301080 A1 EA200301080 A1 EA 200301080A1 EA 200301080 A EA200301080 A EA 200301080A EA 200301080 A EA200301080 A EA 200301080A EA 200301080 A1 EA200301080 A1 EA 200301080A1
Authority
EA
Eurasian Patent Office
Prior art keywords
substituted
unsubstituted
unsubstituted lower
amino group
group
Prior art date
Application number
EA200301080A
Other languages
English (en)
Inventor
Цуйоси Ямагата
Каору Ацуки
Тецудзи Охно
Сиро Сиракура
Акира Карасава
Original Assignee
Киова Хакко Когио Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Киова Хакко Когио Ко., Лтд. filed Critical Киова Хакко Когио Ко., Лтд.
Publication of EA200301080A1 publication Critical patent/EA200301080A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/12—[b,e]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Настоящее изобретение относится к терапевтическому агенту для лечения гиперфункции мочевого пузыря, включающему в качестве активного ингредиента трициклическое соединение, представленное формулойв которой Rпредставляет атом водорода, замещенный или незамещенный низший алкил, замещенную или незамещенную низшую алкоксигруппу или галоген; X-X-Xпредставляет CR=CR-CR=CR, N (O)=CR-CR=CR, CR=CR-N(O)=CR, CR=CR-CR=N(O), CR=CR-O, CR=CR-S, O-CR=CR, S-CR=CRили O-CR=N; Y представляет -CHS-, -CHSO-, -CHSO-, -CHO-, -CH=CH-, -(CH)- -SCH-, -SOCH-, -SOCH- или -OCH- и Rпредставляет атом водорода, замещенный или незамещенный низший алкил, замещенный или незамещенный низший алкенил, замещенную или незамещенную низшую алкоксигруппу, аминогруппу, монозамещенную замещенным или незамещенным низшим алкилом аминогруппу, дизамещенную замещенным или незамещенным низшим алкилом аминогруппу, замещенный или незамещенный арил, замещенный или незамещенный гетероарил, замещенную или незамещенную аралкиламиногруппу, замещенную или незамещенную ариламиногруппу или замещенную или незамещенную гетероалициклическую группу; или его фармацевтически приемлемым солям.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200301080A 2001-03-30 2002-03-29 Терапевтический агент для лечения гиперфункции мочевого пузыря EA200301080A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001099801 2001-03-30
PCT/JP2002/003167 WO2002078710A1 (fr) 2001-03-30 2002-03-29 Medicaments contre l'hyperactivite vesicale

Publications (1)

Publication Number Publication Date
EA200301080A1 true EA200301080A1 (ru) 2004-04-29

Family

ID=18953304

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200301080A EA200301080A1 (ru) 2001-03-30 2002-03-29 Терапевтический агент для лечения гиперфункции мочевого пузыря

Country Status (12)

Country Link
US (1) US7276532B2 (ru)
EP (1) EP1384480A1 (ru)
JP (1) JPWO2002078710A1 (ru)
KR (1) KR20040007476A (ru)
CN (1) CN1498110A (ru)
BR (1) BR0208420A (ru)
CA (1) CA2442463A1 (ru)
EA (1) EA200301080A1 (ru)
HU (1) HUP0303608A3 (ru)
MX (1) MXPA03008725A (ru)
NO (1) NO20034356L (ru)
WO (1) WO2002078710A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1611888A1 (en) * 2003-03-31 2006-01-04 Kyowa Hakko Kogyo Co., Ltd. Antitussives
AR044870A1 (es) * 2003-06-27 2005-10-05 Kyowa Hakko Kogyo Kk Compuesto azufrado triciclico y su uso como agente terapeutico para la vejiga hiperactiva
US20060160887A1 (en) * 2003-07-16 2006-07-20 Kyowa Hakko Kogyo Co., Ltd. Medicinal composition
TW200522943A (en) * 2003-12-11 2005-07-16 Kyowa Hakko Kogyo Kk Fine crystallites and a pharmaceutical composition comprising them
TW200827367A (en) 2006-10-26 2008-07-01 Kyowa Hakko Kogyo Kk A therapeutic agent for irritable bowel syndrome

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014672A1 (fr) 1995-10-16 1997-04-24 Kyowa Hakko Kogyo Co. Ltd. Composes tricycliques
BR9808552A (pt) 1997-04-15 2000-05-23 Kyowa Hakko Kogyo Kk Composto tricìclico ou um sal farmaceuticamente aceitável do mesmo, e, composição farmacêutica

Also Published As

Publication number Publication date
NO20034356D0 (no) 2003-09-29
NO20034356L (no) 2003-11-27
EP1384480A1 (en) 2004-01-28
MXPA03008725A (es) 2004-04-05
HUP0303608A3 (en) 2007-06-28
KR20040007476A (ko) 2004-01-24
HUP0303608A2 (hu) 2004-03-01
JPWO2002078710A1 (ja) 2004-07-22
US7276532B2 (en) 2007-10-02
CN1498110A (zh) 2004-05-19
US20040116459A1 (en) 2004-06-17
WO2002078710A1 (fr) 2002-10-10
BR0208420A (pt) 2004-03-30
CA2442463A1 (en) 2002-10-10

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