EA200300460A1 - NEW DERIVATIVES m-AMINOPHENILIMINOIMIDAZOLIDINE FOR THE TREATMENT OF URINARY HOLDING - Google Patents
NEW DERIVATIVES m-AMINOPHENILIMINOIMIDAZOLIDINE FOR THE TREATMENT OF URINARY HOLDINGInfo
- Publication number
- EA200300460A1 EA200300460A1 EA200300460A EA200300460A EA200300460A1 EA 200300460 A1 EA200300460 A1 EA 200300460A1 EA 200300460 A EA200300460 A EA 200300460A EA 200300460 A EA200300460 A EA 200300460A EA 200300460 A1 EA200300460 A1 EA 200300460A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- denotes
- treatment
- cfh
- chf
- urinary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
В заявке описаны производные м-аминофенилиминоимидазолидина формулы (I) или формулы (II) с новой комбинацией заместителей в фенильном кольцегде Rобозначает F, Cl, Br, CHF, CFH или CF, Rобозначает NRR, где Rпредставляет собой Me, Et, Pr или изо-Pr, a Rпредставляет собой Me, Et или Pr, и R, R, R, каждый независимо друг от друга, обозначает H, Me, F, Cl, Br, CHF, CFH и/или CF, при этом в случае, когда Rобозначает Me, F, Cl, Br, CHF, CFH или CF, Rдополнительно обозначает также H или Me, и/или его фармакологически приемлемые соли, применение таких соединений для получения лекарственных средств, предназначенных прежде всего для лечения недержания мочи, и способ их получения.Отчет о международном поиске был опубликован 2002.07.18.The application describes m-aminophenyliminoimidazolidine derivatives of formula (I) or formula (II) with a new combination of substituents in the phenyl ring, where R denotes F, Cl, Br, CHF, CFH or CF, R N denotes RR, where R Pr, a R represents Me, Et or Pr, and R, R, R, each independently of one another, denotes H, Me, F, Cl, Br, CHF, CFH and / or CF, in which case R denotes Me, F, Cl, Br, CHF, CFH or CF, R is additionally also denotes H or Me, and / or its pharmacologically acceptable salts, the use of such compounds for the preparation of drugs, intended Primarily for the treatment of urinary incontinence, and the way they are obtained. The international search report was published 2002.07.18.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10051005 | 2000-10-14 | ||
| PCT/EP2001/011764 WO2002032876A2 (en) | 2000-10-14 | 2001-10-11 | Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200300460A1 true EA200300460A1 (en) | 2004-02-26 |
Family
ID=7659815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300460A EA200300460A1 (en) | 2000-10-14 | 2001-10-11 | NEW DERIVATIVES m-AMINOPHENILIMINOIMIDAZOLIDINE FOR THE TREATMENT OF URINARY HOLDING |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1328517A2 (en) |
| JP (1) | JP2004511547A (en) |
| KR (1) | KR20030046503A (en) |
| CN (1) | CN1471514A (en) |
| AR (1) | AR035923A1 (en) |
| AU (1) | AU2002215943A1 (en) |
| BG (1) | BG107711A (en) |
| BR (1) | BR0114603A (en) |
| CA (1) | CA2425563A1 (en) |
| CZ (1) | CZ20031333A3 (en) |
| DE (1) | DE10150312A1 (en) |
| EA (1) | EA200300460A1 (en) |
| EC (1) | ECSP034517A (en) |
| EE (1) | EE200300177A (en) |
| HU (1) | HUP0302245A3 (en) |
| IL (1) | IL155338A0 (en) |
| MX (1) | MXPA03003162A (en) |
| NO (1) | NO20031697L (en) |
| PL (1) | PL361359A1 (en) |
| SK (1) | SK4342003A3 (en) |
| WO (1) | WO2002032876A2 (en) |
| YU (1) | YU28203A (en) |
| ZA (1) | ZA200302345B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4168086B1 (en) * | 2008-04-16 | 2008-10-22 | 国立大学法人福井大学 | Imidazoline derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2806811A1 (en) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME |
| CA1201066A (en) * | 1981-11-20 | 1986-02-25 | Alcon Laboratories, Inc. | N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure |
| DE19514579A1 (en) * | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Use of alpha-1-olone agonists for the treatment of urinary incontinence |
-
2001
- 2001-10-11 MX MXPA03003162A patent/MXPA03003162A/en unknown
- 2001-10-11 HU HU0302245A patent/HUP0302245A3/en unknown
- 2001-10-11 EA EA200300460A patent/EA200300460A1/en unknown
- 2001-10-11 CZ CZ20031333A patent/CZ20031333A3/en unknown
- 2001-10-11 BR BR0114603-3A patent/BR0114603A/en not_active Expired - Fee Related
- 2001-10-11 KR KR10-2003-7005143A patent/KR20030046503A/en not_active Application Discontinuation
- 2001-10-11 IL IL15533801A patent/IL155338A0/en unknown
- 2001-10-11 CA CA002425563A patent/CA2425563A1/en not_active Abandoned
- 2001-10-11 EE EEP200300177A patent/EE200300177A/en unknown
- 2001-10-11 CN CNA018170870A patent/CN1471514A/en active Pending
- 2001-10-11 JP JP2002536060A patent/JP2004511547A/en active Pending
- 2001-10-11 YU YU28203A patent/YU28203A/en unknown
- 2001-10-11 EP EP01987747A patent/EP1328517A2/en not_active Withdrawn
- 2001-10-11 PL PL01361359A patent/PL361359A1/en not_active Application Discontinuation
- 2001-10-11 DE DE10150312A patent/DE10150312A1/en not_active Withdrawn
- 2001-10-11 AU AU2002215943A patent/AU2002215943A1/en not_active Abandoned
- 2001-10-11 SK SK434-2003A patent/SK4342003A3/en not_active Application Discontinuation
- 2001-10-11 WO PCT/EP2001/011764 patent/WO2002032876A2/en not_active Application Discontinuation
- 2001-10-12 AR ARP010104787A patent/AR035923A1/en not_active Withdrawn
-
2003
- 2003-03-17 EC EC2003004517A patent/ECSP034517A/en unknown
- 2003-03-26 ZA ZA200302345A patent/ZA200302345B/en unknown
- 2003-04-08 BG BG107711A patent/BG107711A/en active Pending
- 2003-04-11 NO NO20031697A patent/NO20031697L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200302345B (en) | 2004-04-23 |
| SK4342003A3 (en) | 2003-10-07 |
| HUP0302245A2 (en) | 2003-10-28 |
| PL361359A1 (en) | 2004-10-04 |
| BG107711A (en) | 2004-02-27 |
| EP1328517A2 (en) | 2003-07-23 |
| CZ20031333A3 (en) | 2003-08-13 |
| BR0114603A (en) | 2003-10-14 |
| DE10150312A1 (en) | 2002-07-04 |
| EE200300177A (en) | 2003-08-15 |
| CA2425563A1 (en) | 2002-04-25 |
| WO2002032876A2 (en) | 2002-04-25 |
| NO20031697D0 (en) | 2003-04-11 |
| YU28203A (en) | 2006-05-25 |
| NO20031697L (en) | 2003-05-26 |
| CN1471514A (en) | 2004-01-28 |
| IL155338A0 (en) | 2003-11-23 |
| KR20030046503A (en) | 2003-06-12 |
| AU2002215943A1 (en) | 2002-04-29 |
| JP2004511547A (en) | 2004-04-15 |
| AR035923A1 (en) | 2004-07-28 |
| HUP0302245A3 (en) | 2004-01-28 |
| MXPA03003162A (en) | 2004-12-06 |
| WO2002032876A3 (en) | 2002-07-18 |
| ECSP034517A (en) | 2003-04-25 |
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