BG107711A - Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence - Google Patents
Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinenceInfo
- Publication number
- BG107711A BG107711A BG107711A BG10771103A BG107711A BG 107711 A BG107711 A BG 107711A BG 107711 A BG107711 A BG 107711A BG 10771103 A BG10771103 A BG 10771103A BG 107711 A BG107711 A BG 107711A
- Authority
- BG
- Bulgaria
- Prior art keywords
- phenylimino
- amino
- urinary incontinence
- novel
- treating urinary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention relates to m-amino-phenylimino-imidazolidine derivatives with a novel substituent pattern on the phenyl ring, of general formula or of general formula wherein R1 is F, Cl, Br, CH2F, CF2H or CF3; R2 is NR6R7, R6 being Me, Et, Pr or iPr, and R7 being Me, Et or Pr, and R3, R4 and R5 are each, independently of each other, H, Me, F, Cl, Br, CH2F, CF2H and/or CF3, and if R4 is Me, F, Cl, Br, CH2F, CF2H or CF3, then R1 is additionally also H or Me; and or their pharmaceutically compatible salts, to the use thereof of producing medicaments, especially for treating urinary incontinence and to a method for producing the same. 18 claims
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10051005 | 2000-10-14 | ||
| PCT/EP2001/011764 WO2002032876A2 (en) | 2000-10-14 | 2001-10-11 | Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG107711A true BG107711A (en) | 2004-02-27 |
Family
ID=7659815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG107711A Pending BG107711A (en) | 2000-10-14 | 2003-04-08 | Novel m-amino-phenylimino-imidazolidine derivatives for treating urinary incontinence |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1328517A2 (en) |
| JP (1) | JP2004511547A (en) |
| KR (1) | KR20030046503A (en) |
| CN (1) | CN1471514A (en) |
| AR (1) | AR035923A1 (en) |
| AU (1) | AU2002215943A1 (en) |
| BG (1) | BG107711A (en) |
| BR (1) | BR0114603A (en) |
| CA (1) | CA2425563A1 (en) |
| CZ (1) | CZ20031333A3 (en) |
| DE (1) | DE10150312A1 (en) |
| EA (1) | EA200300460A1 (en) |
| EC (1) | ECSP034517A (en) |
| EE (1) | EE200300177A (en) |
| HU (1) | HUP0302245A3 (en) |
| IL (1) | IL155338A0 (en) |
| MX (1) | MXPA03003162A (en) |
| NO (1) | NO20031697L (en) |
| PL (1) | PL361359A1 (en) |
| SK (1) | SK4342003A3 (en) |
| WO (1) | WO2002032876A2 (en) |
| YU (1) | YU28203A (en) |
| ZA (1) | ZA200302345B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4168086B1 (en) * | 2008-04-16 | 2008-10-22 | 国立大学法人福井大学 | Imidazoline derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2806811A1 (en) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME |
| CA1201066A (en) * | 1981-11-20 | 1986-02-25 | Alcon Laboratories, Inc. | N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure |
| DE19514579A1 (en) * | 1995-04-20 | 1996-10-24 | Boehringer Ingelheim Kg | Use of alpha-1-olone agonists for the treatment of urinary incontinence |
-
2001
- 2001-10-11 AU AU2002215943A patent/AU2002215943A1/en not_active Abandoned
- 2001-10-11 CA CA002425563A patent/CA2425563A1/en not_active Abandoned
- 2001-10-11 JP JP2002536060A patent/JP2004511547A/en active Pending
- 2001-10-11 IL IL15533801A patent/IL155338A0/en unknown
- 2001-10-11 CZ CZ20031333A patent/CZ20031333A3/en unknown
- 2001-10-11 PL PL01361359A patent/PL361359A1/en not_active Application Discontinuation
- 2001-10-11 DE DE10150312A patent/DE10150312A1/en not_active Withdrawn
- 2001-10-11 BR BR0114603-3A patent/BR0114603A/en not_active Expired - Fee Related
- 2001-10-11 EA EA200300460A patent/EA200300460A1/en unknown
- 2001-10-11 MX MXPA03003162A patent/MXPA03003162A/en unknown
- 2001-10-11 YU YU28203A patent/YU28203A/en unknown
- 2001-10-11 EE EEP200300177A patent/EE200300177A/en unknown
- 2001-10-11 CN CNA018170870A patent/CN1471514A/en active Pending
- 2001-10-11 KR KR10-2003-7005143A patent/KR20030046503A/en not_active Application Discontinuation
- 2001-10-11 SK SK434-2003A patent/SK4342003A3/en not_active Application Discontinuation
- 2001-10-11 EP EP01987747A patent/EP1328517A2/en not_active Withdrawn
- 2001-10-11 HU HU0302245A patent/HUP0302245A3/en unknown
- 2001-10-11 WO PCT/EP2001/011764 patent/WO2002032876A2/en not_active Application Discontinuation
- 2001-10-12 AR ARP010104787A patent/AR035923A1/en not_active Withdrawn
-
2003
- 2003-03-17 EC EC2003004517A patent/ECSP034517A/en unknown
- 2003-03-26 ZA ZA200302345A patent/ZA200302345B/en unknown
- 2003-04-08 BG BG107711A patent/BG107711A/en active Pending
- 2003-04-11 NO NO20031697A patent/NO20031697L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002032876A2 (en) | 2002-04-25 |
| DE10150312A1 (en) | 2002-07-04 |
| EE200300177A (en) | 2003-08-15 |
| NO20031697D0 (en) | 2003-04-11 |
| WO2002032876A3 (en) | 2002-07-18 |
| MXPA03003162A (en) | 2004-12-06 |
| SK4342003A3 (en) | 2003-10-07 |
| HUP0302245A3 (en) | 2004-01-28 |
| KR20030046503A (en) | 2003-06-12 |
| YU28203A (en) | 2006-05-25 |
| IL155338A0 (en) | 2003-11-23 |
| JP2004511547A (en) | 2004-04-15 |
| CA2425563A1 (en) | 2002-04-25 |
| ECSP034517A (en) | 2003-04-25 |
| AU2002215943A1 (en) | 2002-04-29 |
| PL361359A1 (en) | 2004-10-04 |
| BR0114603A (en) | 2003-10-14 |
| AR035923A1 (en) | 2004-07-28 |
| ZA200302345B (en) | 2004-04-23 |
| EP1328517A2 (en) | 2003-07-23 |
| CZ20031333A3 (en) | 2003-08-13 |
| NO20031697L (en) | 2003-05-26 |
| CN1471514A (en) | 2004-01-28 |
| HUP0302245A2 (en) | 2003-10-28 |
| EA200300460A1 (en) | 2004-02-26 |
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