EA200200569A1 - ARYLOXYPROPANOLAMINES FOR IMPROVED PRODUCTIVITY OF HOME CATTLE - Google Patents

ARYLOXYPROPANOLAMINES FOR IMPROVED PRODUCTIVITY OF HOME CATTLE

Info

Publication number
EA200200569A1
EA200200569A1 EA200200569A EA200200569A EA200200569A1 EA 200200569 A1 EA200200569 A1 EA 200200569A1 EA 200200569 A EA200200569 A EA 200200569A EA 200200569 A EA200200569 A EA 200200569A EA 200200569 A1 EA200200569 A1 EA 200200569A1
Authority
EA
Eurasian Patent Office
Prior art keywords
independently
straight
acceptable salts
structural formula
ring
Prior art date
Application number
EA200200569A
Other languages
Russian (ru)
Inventor
Рэндэлл Брюс Хопкинс
Дина Лори Хэнкок
Майкл Юджин Квимби
Роджер Райан Ротхаар
Джон Арнольд Вернер
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA200200569A1 publication Critical patent/EA200200569A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Feed For Specific Animals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Настоящее изобретение относится к соединению, представленному структурной формулой (I)где R1 обозначает замещенную или незамещенную арильную группу; R2 и R3 независимо обозначают -H, C-Cалкильную группу с прямой или разветвленной цепью; R4 и R5 обозначают независимо -H, C-Cалкильную группу с прямой или разветвленной цепью или, взятые вместе с атомом азота, к которому каждый присоединен, неароматическую гетероциклическую группу; и кольцо A и кольцо B независимо являются незамещенными или дополнительно замещены одним или двумя заместителями, а также их физиологически приемлемым солям. Изобретение также относится к способу усиления роста, повышения эффективности усвоения кормов и/или образования нежирной массы тела у домашнего скота, включающий введение животному эффективного количества одного или нескольких соединений, представленных приведенной структурной формулой, или их физиологически приемлемых солей.Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention relates to a compound represented by the structural formula (I) wherein R1 is a substituted or unsubstituted aryl group; R2 and R3 independently represent a straight or branched -H, C 1 -C 6 alkyl group; R4 and R5 are independently —H, C 1 -C 6 straight or branched chain, or taken together with the nitrogen atom to which each is attached, a non-aromatic heterocyclic group; and ring A and ring B are independently unsubstituted or are additionally substituted with one or two substituents, as well as their physiologically acceptable salts. The invention also relates to a method of enhancing growth, increasing the efficiency of feed absorption and / or the formation of lean body mass in livestock, including administering to the animal an effective amount of one or more compounds represented by the stated structural formula, or their physiologically acceptable salts. The international application was published with international search report.

EA200200569A 1999-11-15 2000-11-13 ARYLOXYPROPANOLAMINES FOR IMPROVED PRODUCTIVITY OF HOME CATTLE EA200200569A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16546099P 1999-11-15 1999-11-15
PCT/US2000/031060 WO2001036413A1 (en) 1999-11-15 2000-11-13 Aryloxy propanolamines for improving livestock production

Publications (1)

Publication Number Publication Date
EA200200569A1 true EA200200569A1 (en) 2003-06-26

Family

ID=22598982

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200569A EA200200569A1 (en) 1999-11-15 2000-11-13 ARYLOXYPROPANOLAMINES FOR IMPROVED PRODUCTIVITY OF HOME CATTLE

Country Status (16)

Country Link
JP (1) JP2003514815A (en)
KR (1) KR20020059730A (en)
CN (1) CN1390213A (en)
AU (1) AU1917401A (en)
BR (1) BR0015578A (en)
CA (1) CA2391654A1 (en)
CO (1) CO5221077A1 (en)
CZ (1) CZ20021644A3 (en)
EA (1) EA200200569A1 (en)
IL (1) IL149570A0 (en)
MX (1) MXPA02004653A (en)
NO (1) NO20022290L (en)
PE (1) PE20010707A1 (en)
PL (1) PL355669A1 (en)
SV (1) SV2002000216A (en)
WO (1) WO2001036413A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0103325D0 (en) 2001-10-04 2001-10-04 Astrazeneca Ab Novel compounds
TWI249515B (en) 2001-11-13 2006-02-21 Theravance Inc Aryl aniline beta2 adrenergic receptor agonists
WO2006014704A1 (en) 2004-07-21 2006-02-09 Theravance, Inc. DIARYL ETHER β2 ADRENERGIC RECEPTOR AGONISTS
US20130224320A1 (en) * 2012-02-23 2013-08-29 Joan Torrent Campmany Process to improve feed efficiency and carcass characteristics of animals
CN111925329B (en) * 2020-09-14 2021-01-12 正大预混料（天津）有限公司 Stilbene triphenol derivative and composition, preparation method and application thereof
CN115611752A (en) * 2022-10-21 2023-01-17 江苏天和制药有限公司 Synthetic refining method of lubabylon intermediate
CN117296990B (en) * 2023-08-08 2024-02-23 河南蒜宝生物科技有限公司 Safe and green composite feed additive containing garlic extract and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
ATE215369T1 (en) * 1996-09-05 2002-04-15 Lilly Co Eli CARBAZOLE ANALOGUES AS SELECTIVE BETA3-ADRENERGIC AGONISTS
US5808080A (en) * 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
CO5011072A1 (en) * 1997-12-05 2001-02-28 Lilly Co Eli ETANOLAMINAS PIRAZINIL SUBSTITUTED AS AGFONISTS OF THE RECEPTORS

Also Published As

Publication number Publication date
KR20020059730A (en) 2002-07-13
NO20022290L (en) 2002-07-09
JP2003514815A (en) 2003-04-22
PL355669A1 (en) 2004-05-04
PE20010707A1 (en) 2001-07-11
WO2001036413A1 (en) 2001-05-25
BR0015578A (en) 2002-07-09
MXPA02004653A (en) 2002-09-02
SV2002000216A (en) 2002-07-16
CO5221077A1 (en) 2002-11-28
CA2391654A1 (en) 2001-05-25
NO20022290D0 (en) 2002-05-14
AU1917401A (en) 2001-05-30
CZ20021644A3 (en) 2002-10-16
IL149570A0 (en) 2002-11-10
CN1390213A (en) 2003-01-08

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