EA200100437A1 - PREGNAN GLUCURONIDES - Google Patents

PREGNAN GLUCURONIDES

Info

Publication number
EA200100437A1
EA200100437A1 EA200100437A EA200100437A EA200100437A1 EA 200100437 A1 EA200100437 A1 EA 200100437A1 EA 200100437 A EA200100437 A EA 200100437A EA 200100437 A EA200100437 A EA 200100437A EA 200100437 A1 EA200100437 A1 EA 200100437A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pregnan
glucuronides
glucuronide
triol
progesterone
Prior art date
Application number
EA200100437A
Other languages
Russian (ru)
Inventor
Кристофер Пол Миллер
Бач Динх Тран
Майкл Дэвид Коллини
Original Assignee
Американ Хоум Продактс Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Американ Хоум Продактс Корпорейшн filed Critical Американ Хоум Продактс Корпорейшн
Publication of EA200100437A1 publication Critical patent/EA200100437A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Данное изобретение относится к 5α-прегнан-3β, (20S),21-триол 20-O-β-D-глюкурониду и 5α-прегнан-3β,20R-диол 20-O-β-D-глюкурониду и к их фармацевтически приемлемым солям, которые используют в качестве прогестеронподобных агентов.Международная заявка была опубликована вместе с отчетом о международном поиске.This invention relates to 5α-pregnan-3β, (20S), 21-triol 20-O-β-D-glucuronide and 5α-pregnan-3β, 20R-diol 20-O-β-D-glucuronide and their pharmaceutically acceptable salts that are used as progesterone-like agents. The international application was published along with an international search report.

EA200100437A 1998-10-13 1999-10-07 PREGNAN GLUCURONIDES EA200100437A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17034298A 1998-10-13 1998-10-13
PCT/US1999/023467 WO2000021977A1 (en) 1998-10-13 1999-10-07 Pregnane glucuronides

Publications (1)

Publication Number Publication Date
EA200100437A1 true EA200100437A1 (en) 2001-10-22

Family

ID=22619512

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100437A EA200100437A1 (en) 1998-10-13 1999-10-07 PREGNAN GLUCURONIDES

Country Status (17)

Country Link
EP (1) EP1121376A1 (en)
JP (1) JP2002527448A (en)
KR (1) KR20010080102A (en)
CN (1) CN1330659A (en)
AR (1) AR020778A1 (en)
AU (1) AU751708B2 (en)
BR (1) BR9914521A (en)
CA (1) CA2346693A1 (en)
CZ (1) CZ20011343A3 (en)
EA (1) EA200100437A1 (en)
HU (1) HUP0103992A3 (en)
IL (1) IL142441A0 (en)
NO (1) NO20011825L (en)
PL (1) PL347270A1 (en)
TW (1) TW499435B (en)
WO (1) WO2000021977A1 (en)
ZA (1) ZA200103012B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0104423D0 (en) * 2001-12-27 2001-12-27 Umecrine Ab Pregnane steroids and their use in the treatment of CNS disorders
KR100440607B1 (en) * 2001-12-28 2004-07-15 주식회사 엘컴사이언스 Pregnan glycoside compounds and preventives and remedies of neurodegenerative disease containing them as active ingredients

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2029011B (en) * 1978-09-01 1983-02-02 Coulson W Use of a synthetic bifunctional ligand for the immunimetric determination of the concentration ratio of two solutes

Also Published As

Publication number Publication date
EP1121376A1 (en) 2001-08-08
CA2346693A1 (en) 2000-04-20
CZ20011343A3 (en) 2002-04-17
NO20011825L (en) 2001-06-05
WO2000021977A1 (en) 2000-04-20
IL142441A0 (en) 2002-03-10
AU751708B2 (en) 2002-08-22
BR9914521A (en) 2001-06-26
PL347270A1 (en) 2002-03-25
JP2002527448A (en) 2002-08-27
AU6511599A (en) 2000-05-01
ZA200103012B (en) 2002-07-11
KR20010080102A (en) 2001-08-22
HUP0103992A3 (en) 2002-12-28
AR020778A1 (en) 2002-05-29
NO20011825D0 (en) 2001-04-10
CN1330659A (en) 2002-01-09
TW499435B (en) 2002-08-21
HUP0103992A2 (en) 2002-04-29

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