EA043933B1 - COMPOSITIONS, KITS, METHODS AND APPLICATIONS FOR CLEANING, DISINFECTING, STERILIZATION AND/OR TREATMENT - Google Patents

Description

This application claims priority and filing date benefit under 35 USC § 119(e) based on U.S. Provisional Patent Application No. 62/721991, filed Aug. 23, 2018, and U.S. Provisional Patent Application No. 62/617263. filed January 14, 2018, the contents of each of which are incorporated herein by reference in their entirety.

In the United States, approximately 46.5 million surgical procedures and even more invasive medical procedures are performed each year, including approximately 5 million gastrointestinal endoscopies. Each procedure will involve bringing the medical device into contact with sterile tissue or mucous membranes of the patient. The main risk of all such procedures is the introduction of pathogens, which can lead to infection. Failure to properly clean, disinfect, and/or sterilize a medical device may expose a patient to body fluids and tissue contaminants from a previous patient, which may result in the transmission of pathogens from person to person or into the environment and infect large numbers of people.

Sterilization of a medical device is preferred because the process destroys or eliminates all forms of microbial life. However, the high temperature and pressure used in sterilization processes are not suitable for temperature-sensitive medical devices. Such heat-sensitive medical devices should be cleaned using a disinfection process. However, one of the problems with currently used disinfection processes is that the type and amount of disinfectant agents used are destructive to the medical device. This reduces the overall lifespan of the medical device, which ultimately leads to increased medical costs due to the need to replace the medical device with a new one earlier. Additionally, given recent infectious outbreaks caused by contaminated medical devices, a more effective disinfection method than currently available methods is needed.

The present invention describes disinfectant compositions, methods and applications that provide excellent cleaning and disinfection of hard surfaces from contaminants/biofilm and/or a medical device, including a temperature-sensitive medical device and a device classified as a critical, semi-critical or non-critical device. At the same time, the described disinfectant compositions, methods and applications are less aggressive than conventional compositions, methods and applications, resulting in a longer service life of the hard surface and/or medical device.

Additionally, during surgical procedures or as a result of injury, there is an urgent need to clean and disinfect wounds. The present invention further describes disinfectant compositions, methods and uses that provide superior cleaning and disinfection of tissue for wound care, preoperative preparation and surgery, the skin surface for dermatological applications and the eye for ophthalmic applications. The present invention also describes compositions, methods and uses for treating patients.

Brief description of the invention

Aspects of the present invention provide a composition comprising hypochlorous acid or free active chlorine and one or more quaternary compounds or organosilicon quaternary compounds. The composition described in the present invention may further contain one or more compounds containing a guanide moiety, one or more metal particles and/or one or more metal salts.

In other aspects, the present invention provides a composition comprising hypochlorous acid or free active chlorine and one or more compounds containing a guanide moiety. The described compound containing a guanide moiety includes an organic compound containing a biguanide functional group, a biguanidine functional group, a triguanide functional group, or any combination thereof. The composition described in the present invention may further contain one or more quaternary compounds or organosilicon quaternary compounds, one or more metal particles and/or one or more metal salts.

In other aspects, the present invention provides a composition comprising one or more alcohols and one or more quaternary compounds or organosilicon quaternary compounds. Alcohols described include ethanol, methanol, isopropyl alcohol, or any combination thereof. The composition described in the present invention may further contain one or more compounds containing a guanide moiety, one or more metal particles and/or one or more metal salts.

In other aspects, the present invention provides a composition containing one or more alcohols and one or more compounds containing a guanide moiety. Alcohols described include ethanol, methanol, isopropyl alcohol, or any combination thereof. The described compound containing a guanide moiety includes an organic compound containing a biguanide functional group, a biguanidine functional group, a triguanide functional group, or any combination thereof. The composition described in the present invention may further contain one or more quaternary compounds or organosilicon quaternary compounds, one or more metal particles and/or one or more metal salts.

In other aspects, the present invention provides a composition comprising hypochlorous acid or free active chlorine and one or more metal particles. The composition described in the present invention may further contain one or more metal salts.

In other aspects, the present invention provides a composition comprising hypochlorous acid or free active chlorine and one or more metal salts. The composition described in the present invention may further contain one or more metal particles.

In other aspects, the present invention discloses a kit comprising one or more containers containing a composition described herein and/or one or more containers containing components of a composition described herein. The described kit further contains one or more delivery or application systems, and/or instructions, and/or container.

In other aspects, the present invention describes a method for cleaning, disinfecting and/or sterilizing a device. The described method involves applying a composition described in the present invention to a device, wherein application of the composition cleans, disinfects and/or sterilizes the device. The described method may further include washing the cleaned, disinfected and/or sterilized device with a washing solution described in the present invention. In other aspects, the present invention provides a composition described in the present invention for use in cleaning, disinfecting and/or sterilizing a device. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a device.

In other aspects, the present invention describes a method for cleaning, disinfecting and/or sterilizing a surface area. The described method involves applying a composition described in the present invention to a surface area, wherein application of the composition cleans, disinfects and/or sterilizes the surface area. The described method may further include rinsing the cleaned, disinfected and/or sterilized surface area with a rinsing solution described in the present invention. In other aspects, the present invention provides a composition described in the present invention for use in cleaning, disinfecting and/or sterilizing a surface area. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a surface area.

In other aspects, the present invention describes a method for cleaning, disinfecting and/or sterilizing a wound on a patient. The described method involves the use of a composition described in the present invention on a patient, wherein the use of the composition cleanses, disinfects and/or sterilizes the wound. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing a wound on a patient. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a wound on a patient. In other aspects, the present invention describes the use of the described composition for the production of a medicament for cleaning, disinfecting and/or sterilizing a wound on a patient.

In other aspects, the present invention describes a method for cleaning, disinfecting and/or sterilizing an infection in a patient. The described method involves the use of a composition described in the present invention on a patient, wherein the use of the composition clears, disinfects and/or sterilizes the infection. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing an infection in a patient. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing an infection in a patient. In other aspects, the present invention describes the use of the described composition for the production of a medicament for cleaning, disinfecting and/or sterilizing an infection in a patient. The infection may be a microbial infection.

In other aspects, the present invention describes a method for treating a wound in a patient. The described method involves the use of a composition described in the present invention on a patient, wherein the use of the composition promotes wound healing. In other aspects, the present invention provides a composition described herein for use in treating a wound in a patient. In other aspects, the present invention describes the use of the described composition for treating a wound in a patient. In other aspects, the present invention describes the use of the described composition for the production of a medicament for treating a wound in a patient.

Detailed Description of the Invention

The composition described in the present invention has increased stability and effectiveness due to the protection of hypochlorous acid. In particular, the composition may protect hypochlorous acid from harmful agents, including, for example, organic compounds, reactive compounds, positively charged molecules, or other compounds that promote or facilitate the decomposition of hypochlorous acid. For example, the compositions described are stable in blood serum and in plastic packaging material. In addition, when protecting hypochlorous acid from this effect, a synergistic effect of effectiveness is observed. This significantly improved efficiency allows the use of smaller amounts of hypochlorous acid in the described compositions. Because hypochlorous acid concentrations above 350 ppm, especially above 500 ppm, cause instability, lower amounts of hypochlorous acid used in the described compositions further increase the stability of the composition. As such, the composition described in the present invention is considered as a replacement for any prior hypochlorous acid compositions currently on the market or in development. Applications include tissue cleaning/disinfection in wound care and surgery, skin cleaning/disinfection in dermatological applications, eye cleaning/disinfection in ophthalmic applications, hard surface cleaning/disinfection of contaminants/biofilm, medical device cleaning/disinfection of contaminants.

The stability of the composition described in the present invention may be due to the positively charged N atom of the quaternary compound or organosilicon quaternary compound, metal particle, metal salt and/or guanide moiety-containing compound described in the present invention. Such compounds appear to form a strong ionic interaction with the negatively charged (OCl ^- ) and the complex thus formed remains stable for a longer period of time compared to individual hypochlorous acid, which is a weaker complex in solution compared with the composition described in the present invention. In addition, the use of 500 ppm or less, in particular 350 ppm or less, hypochlorous acid further increases the stability of the composition described in the present invention.

The increased effectiveness of the composition described in the present invention may result in part from the formation of a chemical bond between the quaternary compound or organosilicon quaternary compound, metal particle, metal salt and/or guanide moiety-containing compound described in the present invention and the substrates, thereby providing long-lasting action in combination with free OCl(-), which has its own antimicrobial effect.

The composition described in the present invention may contain hypochlorous acid. Hypochlorous acid is a weak acid with the chemical formula HOCl, while its molecular formula is written as HClO. As shown in Formula I, hypochlorous acid is a simple molecule with a central oxygen atom linked to chlorine and hydrogen atoms by single bonds, and it has a molecular weight of 52.46 g/mol.

|O n CI (I)

Hypochlorous acid is a colorless solution, and its exact physical properties are variable depending on the concentration of hypochlorous acid in the solution. Hypochlorous acid reacts with bases to form salts called hypochlorites. For example, sodium hypochlorite (NaOCl), the active ingredient in bleach, is formed when hypochlorous acid reacts with sodium hydroxide. Hypochlorous acid also readily interacts with various organic molecules and biomolecules.

The hypochlorous acid solution can be prepared, for example, by dissolving chlorine in water, hydrolysis of chlorine gas, electrolysis of saline, or acidification of hypochlorite. For example, stable hypochlorous salts such as, for example, alkali metal hypochlorites such as sodium hypochlorite, calcium hypochlorite, potassium hypochlorite, lithium hypochlorite and magnesium hypochlorite can be prepared by dissolving chlorine gas in an aqueous alkali metal hydroxide solution such as sodium hydroxide solution , calcium hydroxide solution, potassium hydroxide solution, lithium hydroxide solution, or magnesium hydroxide solution. Hypochlorous acid can also be prepared by dissolving dichlorine monoxide in water. As another example, hypochlorous acid can also be produced by electrolytic treatment of saline solution. In one method, an electrical current is applied to a one-, two-, or three-chamber cell containing a cathode chamber, an anode chamber, and a central saline chamber located between two other chambers, all chambers being separated by a semipermeable membrane. During electrolysis, sodium chloride (NaCl) dissociates into negatively charged chloride (Cl ^- ) and positively charged sodium (Na ⁺ ). In this case, water dissociates into hydroxide (OH ^- ) and hydrogen (H ⁺ ) ions. Negatively charged chlorine (Cl ^- ) and hydroxide (OH ^- ) ions move towards the anode, losing electrons and forming hypochlorous acid (HOCl), as well as hypochlorite ions (OCl ^- ) and oxygen (O ₂ ) and chlorine (Cl ₂ ) gases. The reducing water containing hypochlorous acid is then fed into the collection chamber for subsequent use. Methods for producing hypochlorous acid are described, for example, in patents

- 3 043933

US No. 3914397, No. 4190638, No. 4908215, No. 5322677, No. 6426066, No. 7323118, No. 8062500, No. 8945630, No.

9168318 and No. 9486479, each of which is incorporated herein by reference in its entirety.

In one embodiment, the composition described in the present invention contains an amount of hypochlorous acid that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm , 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm , 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1000 ppm, 1025 ppm, 1050 ppm, 1075 ppm, 1100 ppm, 1125 ppm , 1150 ppm, 1175 ppm, 1200 ppm, 1225 ppm, 1250 ppm, 1275 ppm, 1300 ppm, 1325 ppm, 1350 ppm, 1375 ppm, 1400 ppm, 1425 ppm, 1450 ppm, 1475 ppm, 1500 ppm, 1600 ppm, 1700 ppm, 1800 ppm, 1900 ppm or 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0 .30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0.90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1000 ppm, at least 1025 ppm, at least 1050 ppm, at least 1075 ppm, at least 1100 ppm, at least 1125 ppm, at least 1150 ppm, at least 1175 ppm, at least 1200 ppm, at least 1225 ppm, at least 1250 ppm, at least 1275 ppm, at least 1300 ppm, at least 1325 ppm, at least 1350 ppm, at least 1375 ppm, at least 1400 ppm, at least 1425 ppm, at least 1450 ppm, at least 1475 ppm, at least at least 1500 ppm, at least 1600 ppm, at least 1700 ppm, at least 1800 ppm, at least 1900 ppm or at least 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, not more than 0.05 ppm, not more than 0.10 ppm, not more than 0.20 ppm, not more than 0.30 ppm, no more than 0.40 ppm, no more than 0.50 ppm, no more than 0.60 ppm, no more than 0.70 ppm, no more than 0.80 ppm, no more than 0.90 ppm, no more than 1 ppm, no more than 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm, no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm, no more than 125 ppm, no more than 150 ppm, no more than 175 ppm, no more than 200 ppm, no more than 225 ppm, no more than 250 ppm, no more than 275 ppm, no more than 300 ppm, no more than 325 ppm, no more than 350 ppm, no more than 375 ppm, no more than 400 ppm, no more than 425 ppm, no more than 450 ppm, no more than 475 ppm, no more than 500 ppm, no more than 525 ppm, no more than 550 ppm, no more than 575 ppm, no more than 600 ppm, no more than 625 ppm, no more than 650 ppm, no more than 675 ppm, no more than 700 ppm, no more than 725 ppm, no more than 750 ppm, no more than 775 ppm, no more than 800 ppm, no more than 825 ppm, no more than 850 ppm, no more than 875 ppm, no more than 900 ppm, no more than 925 ppm, no more than 950 ppm, no more than 975 ppm, no more than 1000 ppm, no more than 1025 ppm, no more than 1050 ppm, no more than 1075 ppm, no more than 1100 ppm, no more than 1125 ppm, no more

1150 ppm, no more than 1175 ppm, no more than 1200 ppm, no more than 1225 ppm, no more than 1250 ppm, no more

1275 ppm, no more than 1300 ppm, no more than 1325 ppm, no more than 1350 ppm, no more than 1375 ppm, no more

1400 ppm, no more than 1425 ppm, no more than 1450 ppm, no more than 1475 ppm, no more than 1500 ppm, no more

1600 ppm, not more than 1700 ppm, not more than 1800 ppm, not more than 1900 ppm or not more than 2000 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount, for example, from about 0.5 ppm to about 20 ppm, from about 0.5 ppm to about 25 ppm, from about 0.5 ppm to about 30 ppm, from about 0.5 ppm to about 35 ppm, from about 0.5 ppm to about 40 ppm, from about 0.5 ppm to about 45 ppm, from about 0.5 ppm to about 50 ppm, from approximately 0.5 ppm to approximately

- 4 043933 ppm, from about 0.5 ppm to about 60 ppm, from about 0.5 ppm to about 65 ppm, from about 0.5 ppm to about 70 ppm, from about 0.5 ppm to about 75 ppm, from about 0.5 ppm to about 80 ppm, from about 0.5 ppm to about 85 ppm, from about 0.5 ppm to about 90 ppm, from about 0.5 ppm to about 95 ppm, from about 0.5 ppm to about 100 ppm, from about 0.75 ppm to about 20 ppm, from about 0.75 ppm to about 25 ppm, from about 0.75 ppm to about 30 ppm, from about 0.75 ppm to about 35 ppm, from about 0.75 ppm to about 40 ppm, from about 0.75 ppm to about 45 ppm, from about 0.75 ppm to about 50 ppm, from about 0.75 ppm to about 55 ppm, from about 0.75 ppm to about 60 ppm, from about 0.75 ppm to about 65 ppm, from about 0.75 ppm to about 70 ppm, from about 0.75 ppm to about 75 ppm, from about 0.75 ppm to about 80 ppm, from about 0 .75 ppm to about 85 ppm, from about 0.75 ppm to about 90 ppm, from about 0.75 ppm to about 95 ppm, from about 0.75 ppm to about 100 ppm, from about 1 ppm to about 20 ppm, from about 1 ppm to about 25 ppm, from about 1 ppm to about 30 ppm, from about 1 ppm to about 35 ppm, from about 1 ppm to about 40 ppm, from about 1 ppm to about 45 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 55 ppm, from about 1 ppm to about 60 ppm, from about 1 ppm to about 65 ppm, from about 1 ppm to about 70 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 80 ppm, about 1 ppm to about 85 ppm, about 1 ppm to about 90 ppm, about 1 ppm to about 95 ppm, about 1 ppm to about 100 ppm, about 5 ppm to about 20 ppm, from about 5 ppm to about 25 ppm, from about 5 ppm to about 30 ppm, from about 5 ppm to about 35 ppm, from about 5 ppm to about 40 ppm, from about 5 ppm to about 45 ppm, from about 5 ppm to about 50 ppm, about 5 ppm to about 55 ppm, about 5 ppm to about 60 ppm, about 5 ppm to about 65 ppm, about 5 ppm to about 70 ppm, about 5 ppm to about 75 ppm, from about 5 ppm to about 80 ppm, from about 5 ppm to about 85 ppm, from about 5 ppm to about 90 ppm, from about 5 ppm to about 95 ppm, from about 5 ppm to about 100 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 35 ppm, from about 10 ppm to about 40 ppm, from about 10 ppm to about 45 ppm , from about 10 ppm to about 50 ppm, from about 10 ppm to about 55 ppm, from about 10 ppm to about 60 ppm, from about 10 ppm to about 65 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 85 ppm, from about 10 ppm to about 90 ppm, from about 10 ppm to about 95 ppm, or from about 10 ppm to about 100 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount, for example, from about 1 ppm to about 25 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 100 ppm, about 1 ppm to about 125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, from about 1 ppm to about 250 ppm, from about 1 ppm to about 275 ppm, from about 1 ppm to about 300 ppm, from about 1 ppm to about 325 ppm, from about 1 ppm to about 350 ppm, from about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, from about 10 ppm to about 125 ppm, from about 10 ppm to about 150 ppm, from about 10 ppm to about 175 ppm, from about 10 ppm to about 200 ppm, from about 10 ppm to about 225 ppm, from about 10 ppm to about 250 ppm, from about 10 ppm to about 275 ppm, from about 10 ppm to about 300 ppm, from about 10 ppm to about 325 ppm, from about 10 ppm to about 350 ppm, from about 10 ppm to about 375 ppm , from about 10 ppm to about 400 ppm, from about 25 ppm to about 50 ppm, from about 25 ppm to about 75 ppm, from about 25 ppm to about 100 ppm, from about 25 ppm to about 125 ppm, from about 25 ppm to about 150 ppm, from about 25 ppm to about 175 ppm, from about 25 ppm to about 200 ppm, from about 25 ppm to about 225 ppm, from about 25 ppm to about 250 ppm, from about 25 ppm to about 275 ppm, from about 25 ppm to about 300 ppm, from about 25 ppm to about 325 ppm, from about 25 ppm to about 350 ppm, from about 25 ppm to about 375 ppm, from about 25 ppm to about 400 ppm, from about 50 ppm to about 75 ppm, from about 50 ppm to about 100 ppm, from about 50 ppm to about 125 ppm, from about 50 ppm to about 150 ppm, from about 50 ppm to about 175 ppm, from about 50 ppm to about 200 ppm, from about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, from about 50 ppm to about 375 ppm, from about 50 ppm to about 400 ppm, from about 75 ppm to about 100 ppm, from about 75 ppm to about 125 ppm, from about 75 ppm to about 150 ppm, from about 75 ppm to about 175 ppm, from about 75 ppm to about 200 ppm, from about 75 ppm to about 225 ppm, from at

- 5 043933 approximately 75 ppm to about 250 ppm, from about 75 ppm to about 275 ppm, from about 75 ppm to about 300 ppm, from about 75 ppm to about 325 ppm, from about 75 ppm to about 350 ppm, from about 75 ppm to about 375 ppm, from about 75 ppm to about 400 ppm, from about 100 ppm to about 125 ppm, from about 100 ppm to about 150 ppm, from about 100 ppm to about 175 ppm, from about 100 ppm to about 200 ppm , from about 100 ppm to about 225 ppm, from about 100 ppm to about 250 ppm, from about 100 ppm to about 275 ppm, from about 100 ppm to about 300 ppm, from about 100 ppm to about 325 ppm, from about 100 ppm to about 350 ppm, from about 100 ppm to about 375 ppm, from about 100 ppm to about 400 ppm, from about 150 ppm to about 175 ppm, from about 150 ppm to about 200 ppm, from about 150 ppm to about 225 ppm, from about 150 ppm to about 250 ppm, from about 150 ppm to about 275 ppm, from about 150 ppm to about 300 ppm, from about 150 ppm to about 325 ppm, from about 150 ppm to about 350 ppm, from about 150 ppm to about 375 ppm, from about 150 ppm to about 400 ppm, from about 200 ppm to about 225 ppm, from about 200 ppm to about 250 ppm, from about 200 ppm to about 275 ppm, from about 200 ppm to about 300 ppm, from about 200 ppm to about 325 ppm, about 200 ppm to about 350 ppm, about 200 ppm to about 375 ppm, about 200 ppm to about 400 ppm, about 250 ppm to about 275 ppm, about 250 ppm to about 300 ppm, from about 250 ppm to about 325 ppm, from about 250 ppm to about 350 ppm, from about 250 ppm to about 375 ppm, from about 250 ppm to about 400 ppm, from about 300 ppm to about 325 ppm, from about 300 ppm to about 350 ppm, about 300 ppm to about 375 ppm, about 300 ppm to about 400 ppm, about 350 ppm to about 375 ppm, about 350 ppm to about 400 ppm, or about 375 ppm to about 400 ppm

In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount, for example, from about 400 ppm to about 500 ppm, from about 400 ppm to about 600 ppm, from about 400 ppm to about 700 ppm, from from about 400 ppm to about 800 ppm, from about 400 ppm to about 900 ppm, from about 400 ppm to about 1000 ppm, from about 400 ppm to about 1100 ppm, from about 400 ppm to about 1200 ppm, from about 400 ppm to about 1300 ppm, from about 400 ppm to about 1400 ppm, from about 400 ppm to about 1500 ppm, from about 400 ppm to about 1600 ppm, from about 400 ppm to about 1700 ppm, from about 400 ppm to about 1800 ppm, from about 400 ppm to about 1900 ppm, from about 400 ppm to about 2000 ppm, from about 500 ppm to about 600 ppm, from about 500 ppm to about 700 ppm, from about 500 ppm to about 800 ppm, from about 500 ppm to about 900 ppm, from about 500 ppm to about 1000 ppm, from about 500 ppm to about 1100 ppm, from about 500 ppm to about 1200 ppm, from about 500 ppm to about 1300 ppm, from about 500 ppm to about 1400 ppm, from about 500 ppm to about 1500 ppm, from about 500 ppm to about 1600 ppm, from about 500 ppm to about 1700 ppm, from about 500 ppm to about 1800 ppm, from about 500 ppm to about 1900 ppm, from about 500 ppm to about 2000 ppm , from about 600 ppm to about 700 ppm, from about 600 ppm to about 800 ppm, from about 600 ppm to about 900 ppm, from about 600 ppm to about 1000 ppm, from about 600 ppm to about 1100 ppm, from about 600 ppm to about 1200 ppm, from about 600 ppm to about 1300 ppm, from about 600 ppm to about 1400 ppm, from about 600 ppm to about 1500 ppm, from about 600 ppm to about 1600 ppm, from about 600 ppm to about 1700 ppm, from about 600 ppm to about 1800 ppm, from about 600 ppm to about 1900 ppm, from about 600 ppm to about 2000 ppm, from about 700 ppm to about 800 ppm, from about 700 ppm to about 900 ppm, from about 700 ppm to about 1000 ppm, from about 700 ppm to about 1100 ppm, from about 700 ppm to about 1200 ppm, from about 700 ppm to about 1300 ppm, from about 700 ppm to about 1400 ppm, from about 700 ppm to about 1500 ppm, from from about 700 ppm to about 1600 ppm, from about 700 ppm to about 1700 ppm, from about 700 ppm to about 1800 ppm, from about 700 ppm to about 1900 ppm, from about 700 ppm to about 2000 ppm, from about 800 ppm to about 900 ppm, from about 800 ppm to about 1000 ppm, from about 800 ppm to about 1100 ppm, from about 800 ppm to about 1200 ppm, from about 800 ppm to about 1300 ppm, from about 800 ppm to about 1400 ppm, from about 800 ppm to about 1500 ppm, from about 800 ppm to about 1600 ppm, from about 800 ppm to about 1700 ppm, from about 800 ppm to about 1800 ppm, from about 800 ppm to about 1900 ppm, from about 800 ppm to about 2000 ppm, from about 900 ppm to about 1000 ppm, from about 900 ppm to about 1100 ppm, from about 900 ppm to about 1200 ppm, from about 900 ppm to about 1300 ppm, from about 900 ppm to about 1400 ppm, from about 900 ppm to about 1500 ppm, from about 900 ppm to about 1600 ppm, from about 900 ppm to about 1700 ppm, from about 900 ppm to about 1800 ppm, from about 900 ppm to about 1900 ppm, from about 900 ppm to about 2000 ppm , from about 1000 ppm to about 1100 ppm, from about 1000 ppm to about 1200 ppm, from about 1000 ppm to about 1300 ppm, from about 1000 ppm to about 1400 ppm, from about 1000 ppm to about 1500 ppm, from example

- 6 043933 but 1000 ppm to about 1600 ppm, from about 1000 ppm to about 1700 ppm, from about 1000 ppm to about 1800 ppm, from about 1000 ppm to about 1900 ppm, from about 1000 ppm to about 2000 ppm, from about 1100 ppm to about 1200 ppm, from about 1100 ppm to about 1300 ppm, from about 1100 ppm to about 1400 ppm, from about 1100 ppm to about 1500 ppm, from about 1100 ppm to about 1600 ppm, from about 1100 ppm to about 1700 ppm , from about 1100 ppm to about 1800 ppm, from about 1100 ppm to about 1900 ppm, from about 1100 ppm to about 2000 ppm, from about 1200 ppm to about 1300 ppm, from about 1200 ppm to about 1400 ppm, from about 1200 ppm to about 1500 ppm, from about 1200 ppm to about 1600 ppm, from about 1200 ppm to about 1700 ppm, from about 1200 ppm to about 1800 ppm, from about 1200 ppm to about 1900 ppm, from about 1200 ppm to about 2000 ppm, from about 1300 ppm to about 1400 ppm, from about 1300 ppm to about 1500 ppm, from about 1300 ppm to about 1600 ppm, from about 1300 ppm to about 1700 ppm, from about 1300 ppm to about 1800 ppm, from about 1300 ppm to from about 1900 ppm, from about 1300 ppm to about 2000 ppm, from about 1400 ppm to about 1500 ppm, from about 1400 ppm to about 1600 ppm, from about 1400 ppm to about 1700 ppm, from about 1400 ppm to about 1800 ppm, from from about 1400 ppm to about 1900 ppm, from about 1400 ppm to about 2000 ppm, from about 1500 ppm to about 1600 ppm, from about 1500 ppm to about 1700 ppm, from about 1500 ppm to about 1800 ppm, from about 1500 ppm to about 1900 ppm, from about 1500 ppm to about 2000 ppm, from about 1600 ppm to about 1700 ppm, from about 1600 ppm to about 1800 ppm, from about 1600 ppm to about 1900 ppm, from about 1600 ppm to about 2000 ppm, from about 1700 ppm to about 1800 ppm, about 1700 ppm to about 1900 ppm, about 1700 ppm to about 2000 ppm, about 1800 ppm to about 1900 ppm, about 1800 ppm to about 2000 ppm, or about 1900 ppm to about 2000 ppm

In aspects according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, about 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14% , approximately 0.15%, approximately 0.16%, approximately 0.17%, approximately 0.18%, approximately 0.19%, approximately 0.2%, approximately 0.25%, approximately 0.3%, approximately 0.35%, about 0.4%, about 0.45%, or about 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, at least 0.10%, at least 0.11%, at least 0.12%, at least 0 .13%, at least 0.14%, at least 0.15%, at least 0.16%, at least 0.17%, at least 0.18%, at least 0.19 %, at least 0.2%, at least 0.25%, at least 0.3%, at least 0.35%, at least 0.4%, at least 0.45% or at least 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount of, for example, not more than 0.10%, not more than 0.11%, not more than 0.12%, not more than 0.13%, not more than 0.14%, not more than 0.15%, not more than 0.16%, not more than 0.17%, not more than 0.18%, not more than 0.19%, not more than 0.2%, not more than 0.25%, no more than 0.3%, no more than 0.35%, no more than 0.4%, no more than 0.45% or no more than 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains hypochlorous acid in an amount, for example, from about 0.10% to about 0.15%, from about 0.10% to about 0.20%, from about 0.10% to about 0.25%, from about 0.10% to about 0.30%, from about 0.10% to about 0.35%, from about 0.10% to about 0.40%, from about 0.10% to about 0.45%, from about 0.10% to about 0.50%, from about 0.20% to about 0.25%, from about 0.20% to about 0.30 %, from approximately

0.20% to about 0.35%, from about 0.20% to about 0.40%, from about 0.20% to about

0.45%, from about 0.20% to about 0.50%, from about 0.30% to about 0.35%, from about

0.30% to about 0.40%, from about 0.30% to about 0.45%, from about 0.30% to about

0.50%, from about 0.40% to about 0.45%, or from about 0.40% to about 0.50% by weight of the composition.

In one embodiment, the composition described in the present invention does not contain hypochlorous acid.

The concentration of hypochlorous acid in a solution can be described as the free active chlorine content in parts per million. Hypochlorous acid is in equilibrium with hypochlorite ions (OCl ^- ) and dissolved chlorine gas (Cl ₂ ). The degree of equilibrium is determined primarily by the salt concentration and the pH value of the solution. Temperature also affects the free chlorine component ratio. Therefore, it is necessary to know the FAC and pH values to understand the amount of chlorine present as hypochlorous acid. In general, at a pH in the range of about 4.0 to about 5.6, about 100% of the available chlorine is present as HOCl. As pH decreases below about 4, dissolved chlorine gas (Cl2) increases. Thus, at a pH of about 3, about 90% of the available chlorine is present as hypochlorous acid, at a pH of about 2, about 75% of the available chlorine is present as hypochlorous acid, at a pH of about 1.5, about 50% of the available chlorine is present as hypochlorous acid, whereas with

- 7 043933 pH approximately 1 approximately 25% of the available chlorine is present in the form of hypochlorous acid. As the pH increases above about 5.6, the content of hypochlorite ions (OCl ^- ) increases. Thus, at a pH of about 6.5, about 90% of the available chlorine is present as hypochlorous acid, at a pH of about 7, about 75% of the available chlorine is present as hypochlorous acid, at a pH of about 7.5, about 50% of the available chlorine is present as hypochlorous acid. acid, whereas at a pH of about 8, about 25% of the available chlorine is present as hypochlorous acid.

The amount of chlorine can be measured using methods known in the art, such as the DPD colorimetric method (Lamotte Company, Chestertown, Md.), UV spectrophotometry, or other known methods established by the Environmental Protection Agency. In the DPD colorimetric method, the yellow color is produced by the reaction of free chlorine with N,N-diethyl-n-phenylenediamine (DPD) and the intensity is measured using a calibrated colorimeter that provides the result in parts per million. Further addition of potassium iodide turns the solution pink, which allows determination of the total chlorine content.

In one embodiment, the composition described in the present invention contains free active chlorine in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm , 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1000 ppm, 1025 ppm, 1050 ppm, 1075 ppm, 1100 ppm, 1125 ppm, 1150 ppm, 1175 ppm, 1200 ppm, 1225 ppm, 1250 ppm, 1275 ppm, 1300 ppm, 1325 ppm, 1350 ppm, 1375 ppm, 1400 ppm, 1425 ppm, 1450 ppm, 1475 ppm, 1 500 ppm, 1600 ppm , 1700 ppm, 1800 ppm, 1900 ppm or 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0.30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0, 90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm , at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, according to at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm , at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, according at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1000 ppm, at least 1025 ppm, at least 1050 ppm, at least 1075 ppm, at least 1100 ppm, at least 1125 ppm, at least 1150 ppm, at least 1175 ppm, at least 1200 ppm, at least 1225 ppm, at least 1250 ppm, at least 1275 ppm , at least 1300 ppm, at least 1325 ppm, at least 1350 ppm, at least 1375 ppm, at least 1400 ppm, at least 1425 ppm, at least 1450 ppm, at least 1475 ppm, according at least 1500 ppm, at least 1600 ppm, at least 1700 ppm, at least 1800 ppm, at least 1900 ppm or at least 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, no more than 0.05 ppm, no more than 0.10 ppm, no more than 0.20 ppm, no more than 0.30 ppm , no more than 0.40 ppm, no more than 0.50 ppm, no more than 0.60 ppm, no more than 0.70 ppm, no more than 0.80 ppm, no more than 0.90 ppm, no more than 1 ppm, no more 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm, no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm, no more 125 ppm, no more than 150 ppm, no more than 175 ppm, no more than 200 ppm, no more than 225 ppm, no more than 250 ppm, no more than 275 ppm, no more than 300 ppm, no more than 325 ppm, no more than 350 ppm, no more 375 ppm, no more than 400 ppm, no more than 425 ppm, no more than 450 ppm, no more than 475 ppm, no more than 500 ppm, no more than 525 ppm, no more than 550 ppm, no more than 575 ppm, no more than 600 ppm, no more 625 ppm, no more than 650 ppm, no more than 675 ppm, no more than 700 ppm, no more than 725 ppm, no more than 750 ppm, no more than 775 ppm, no more than 800 ppm, no more than 825 ppm, no more than 850 ppm, no more

- 8 043933

875 ppm, no more than 900 ppm, no more than 925 ppm, no more than 950 ppm, no more than 975 ppm, no more than 1000 ppm, no more than 1025 ppm, no more than 1050 ppm, no more than 1075 ppm, no more than 1100 ppm, no more 1125 ppm, no more than 1150 ppm, no more than 1175 ppm, no more than 1200 ppm, no more than 1225 ppm, no more than 1250 ppm, no more than 1275 ppm, no more than 1300 ppm, no more than 1325 ppm, no more than 1350 ppm, no more 1375 ppm, no more than 1400 ppm, no more than 1425 ppm, no more than 1450 ppm, no more than 1475 ppm, no more than 1500 ppm, no more

1600 ppm, not more than 1700 ppm, not more than 1800 ppm, not more than 1900 ppm or not more than 2000 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount, for example, from about 0.5 ppm to about 20 ppm, from about 0.5 ppm to about 25 ppm, from about 0.5 ppm to about 30 ppm, from about 0.5 ppm to about 35 ppm, from about 0.5 ppm to about 40 ppm, from about 0.5 ppm to about 45 ppm, from about 0.5 ppm to about 50 ppm, from about 0.5 ppm to about 55 ppm, from about 0.5 ppm to about 60 ppm, from about 0.5 ppm to about 65 ppm, from about 0.5 ppm to about 70 ppm, from about 0.5 ppm to about 75 ppm, from about 0.5 ppm to about 80 ppm, from about 0.5 ppm to about 85 ppm, from about 0.5 ppm to about 90 ppm, from about 0.5 ppm to about 95 ppm, from about 0.5 ppm to about 100 ppm, about 0.75 ppm to about 20 ppm, about 0.75 ppm to about 25 ppm, about 0.75 ppm to about 30 ppm, about 0.75 ppm to about 35 ppm, from about 0.75 ppm to about 40 ppm, from about 0.75 ppm to about 45 ppm, from about 0.75 ppm to about 50 ppm, from about 0.75 ppm to about 55 ppm, from about 0.75 ppm to about 60 ppm, from about 0.75 ppm to about 65 ppm, from about 0.75 ppm to about 70 ppm, from about 0.75 ppm to about 75 ppm, from about 0.75 ppm to about 80 ppm, from about 0.75 ppm to about 85 ppm, from about 0.75 ppm to about 90 ppm, from about 0.75 ppm to about 95 ppm, from about 0.75 ppm to about 100 ppm, from about 1 ppm to about 20 ppm, from about 1 ppm to about 25 ppm, from about 1 ppm to about 30 ppm, from about 1 ppm to about 35 ppm, from about 1 ppm to about 40 ppm, from about 1 ppm to about 45 ppm , from about 1 ppm to about 50 ppm, from about 1 ppm to about 55 ppm, from about 1 ppm to about 60 ppm, from about 1 ppm to about 65 ppm, from about 1 ppm to about 70 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 80 ppm, from about 1 ppm to about 85 ppm, from about 1 ppm to about 90 ppm, from about 1 ppm to about 95 ppm, from about 1 ppm to about 100 ppm, from about 5 ppm to about 20 ppm, from about 5 ppm to about 25 ppm, from about 5 ppm to about 30 ppm, from about 5 ppm to about 35 ppm, from about 5 ppm to about 40 ppm, from about 5 ppm to about 45 ppm, from about 5 ppm to about 50 ppm, from about 5 ppm to about 55 ppm, from about 5 ppm to about 60 ppm, from about 5 ppm to about 65 ppm, from about 5 ppm to about 70 ppm, from about 5 ppm to about 75 ppm, about 5 ppm to about 80 ppm, about 5 ppm to about 85 ppm, about 5 ppm to about 90 ppm, about 5 ppm to about 95 ppm, about 5 ppm to about 100 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 35 ppm, from about 10 ppm to about 40 ppm, from about 10 ppm to about 45 ppm, from about 10 ppm to about 50 ppm, from about 10 ppm to about 55 ppm, from about 10 ppm to about 60 ppm, from about 10 ppm to about 65 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 85 ppm, from about 10 ppm to about 90 ppm, from about 10 ppm to about 95 ppm, or from about 10 ppm to about 100 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount, for example, from about 1 ppm to about 25 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 100 ppm, from about 1 ppm to about 125 ppm, from about 1 ppm to about 150 ppm, from about 1 ppm to about 175 ppm, from about 1 ppm to about 200 ppm, from about 1 ppm to about 225 ppm, from about 1 ppm to about 250 ppm, from about 1 ppm to about 275 ppm, from about 1 ppm to about 300 ppm, from about 1 ppm to about 325 ppm, from about 1 ppm to about 350 ppm, from about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, from about 10 ppm to about 125 ppm, from about 10 ppm to about 150 ppm, from about 10 ppm to about 175 ppm, from about 10 ppm to about 200 ppm, from about 10 ppm to about 225 ppm, from about 10 ppm to about 250 ppm, from about 10 ppm to about 275 ppm, from about 10 ppm to about 300 ppm, from about 10 ppm to about 325 ppm, from about 10 ppm to about 350 ppm, from about 10 ppm to about 375 ppm, from about 10 ppm to about 400 ppm, from about 25 ppm to about 50 ppm, from about 25 ppm to about 75 ppm, from about 25 ppm to about 100 ppm, from about 25 ppm to about 125 ppm, from about 25 ppm to about 150 ppm, from about 25 ppm to about 175 ppm, from about 25 ppm to about 200 ppm, from about 25 ppm to about 225 ppm, from about 25 ppm to about 250 ppm, from about 25 ppm to

- 9 043933 about 275 ppm, from about 25 ppm to about 300 ppm, from about 25 ppm to about 325 ppm, from about 25 ppm to about 350 ppm, from about 25 ppm to about 375 ppm, from about 25 ppm to about 400 ppm, from about 50 ppm to about 75 ppm, from about 50 ppm to about 100 ppm, from about 50 ppm to about 125 ppm, from about 50 ppm to about 150 ppm, from about 50 ppm to about 175 ppm, from about 50 ppm to about 200 ppm, from about 50 ppm to about 225 ppm, from about 50 ppm to about 250 ppm, from about 50 ppm to about 275 ppm, from about 50 ppm to about 300 ppm, from about 50 ppm to about 325 ppm , from about 50 ppm to about 350 ppm, from about 50 ppm to about 375 ppm, from about 50 ppm to about 400 ppm, from about 75 ppm to about 100 ppm, from about 75 ppm to about 125 ppm, from about 75 ppm to about 150 ppm, from about 75 ppm to about 175 ppm, from about 75 ppm to about 200 ppm, from about 75 ppm to about 225 ppm, from about 75 ppm to about 250 ppm, from about 75 ppm to about 275 ppm, from about 75 ppm to about 300 ppm, from about 75 ppm to about 325 ppm, from about 75 ppm to about 350 ppm, from about 75 ppm to about 375 ppm, from about 75 ppm to about 400 ppm, from about 100 ppm to about 125 ppm, from about 100 ppm to about 150 ppm, from about 100 ppm to about 175 ppm, from about 100 ppm to about 200 ppm, from about 100 ppm to about 225 ppm, from about 100 ppm to about 250 ppm, from from about 100 ppm to about 275 ppm, from about 100 ppm to about 300 ppm, from about 100 ppm to about 325 ppm, from about 100 ppm to about 350 ppm, from about 100 ppm to about 375 ppm, from about 100 ppm to about 400 ppm, from about 150 ppm to about 175 ppm, from about 150 ppm to about 200 ppm, from about 150 ppm to about 225 ppm, from about 150 ppm to about 250 ppm, from about 150 ppm to about 275 ppm, from about 150 ppm to about 300 ppm, from about 150 ppm to about 325 ppm, from about 150 ppm to about 350 ppm, from about 150 ppm to about 375 ppm, from about 150 ppm to about 400 ppm, from about 200 ppm to about 225 ppm, from about 200 ppm to about 250 ppm, from about 200 ppm to about 275 ppm, from about 200 ppm to about 300 ppm, from about 200 ppm to about 325 ppm, from about 200 ppm to about 350 ppm, from about 200 ppm to about 375 ppm, from about 200 ppm to about 400 ppm, from about 250 ppm to about 275 ppm, from about 250 ppm to about 300 ppm, from about 250 ppm to about 325 ppm, from about 250 ppm to about 350 ppm , from about 250 ppm to about 375 ppm, from about 250 ppm to about 400 ppm, from about 300 ppm to about 325 ppm, from about 300 ppm to about 350 ppm, from about 300 ppm to about 375 ppm, from about 300 ppm to about 400 ppm, from about 350 ppm to about 375 ppm, from about 350 ppm to about 400 ppm, or from about 375 ppm to about 400 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount, for example, from about 400 ppm to about 500 ppm, from about 400 ppm to about 600 ppm, from about 400 ppm to about 700 ppm, from about 400 ppm to about 800 ppm, from about 400 ppm to about 900 ppm, from about 400 ppm to about 1000 ppm, from about 400 ppm to about 1100 ppm, from about 400 ppm to about 1200 ppm, from about 400 ppm to from about 1300 ppm, from about 400 ppm to about 1400 ppm, from about 400 ppm to about 1500 ppm, from about 400 ppm to about 1600 ppm, from about 400 ppm to about 1700 ppm, from about 400 ppm to about 1800 ppm, from from about 400 ppm to about 1900 ppm, from about 400 ppm to about 2000 ppm, from about 500 ppm to about 600 ppm, from about 500 ppm to about 700 ppm, from about 500 ppm to about 800 ppm, from about 500 ppm to about 900 ppm, from about 500 ppm to about 1000 ppm, from about 500 ppm to about 1100 ppm, from about 500 ppm to about 1200 ppm, from about 500 ppm to about 1300 ppm, from about 500 ppm to about 1400 ppm, from about 500 ppm to about 1500 ppm, from about 500 ppm to about 1600 ppm, from about 500 ppm to about 1700 ppm, from about 500 ppm to about 1800 ppm, from about 500 ppm to about 1900 ppm, from about 500 ppm to about 2000 ppm, from about 600 ppm to about 700 ppm, from about 600 ppm to about 800 ppm, from about 600 ppm to about 900 ppm, from about 600 ppm to about 1000 ppm, from about 600 ppm to about 1100 ppm, from about 600 ppm to about 1200 ppm, from about 600 ppm to about 1300 ppm, from about 600 ppm to about 1400 ppm, from about 600 ppm to about 1500 ppm, from about 600 ppm to about 1600 ppm, from about 600 ppm to about 1700 ppm , from about 600 ppm to about 1800 ppm, from about 600 ppm to about 1900 ppm, from about 600 ppm to about 2000 ppm, from about 700 ppm to about 800 ppm, from about 700 ppm to about 900 ppm, from about 700 ppm to about 1000 ppm, from about 700 ppm to about 1100 ppm, from about 700 ppm to about 1200 ppm, from about 700 ppm to about 1300 ppm, from about 700 ppm to about 1400 ppm, from about 700 ppm to about 1500 ppm, from about 700 ppm to about 1600 ppm, from about 700 ppm to about 1700 ppm, from about 700 ppm to about 1800 ppm, from about 700 ppm to about 1900 ppm, from about 700 ppm to about 2000 ppm, from about 800 ppm to about 900 ppm, about 800 ppm to about 1000 ppm, about 800 ppm to about 1100 ppm, about 800 ppm to

- 10 043933 about 1200 ppm, from about 800 ppm to about 1300 ppm, from about 800 ppm to about 1400 ppm, from about 800 ppm to about 1500 ppm, from about 800 ppm to about 1600 ppm, from about 800 ppm to about 1700 ppm, from about 800 ppm to about 1800 ppm, from about 800 ppm to about 1900 ppm, from about 800 ppm to about 2000 ppm, from about 900 ppm to about 1000 ppm, from about 900 ppm to about 1100 ppm, from about 900 ppm to about 1200 ppm, from about 900 ppm to about 1300 ppm, from about 900 ppm to about 1400 ppm, from about 900 ppm to about 1500 ppm, from about 900 ppm to about 1600 ppm, from about 900 ppm to about 1700 ppm , from about 900 ppm to about 1800 ppm, from about 900 ppm to about 1900 ppm, from about 900 ppm to about 2000 ppm, from about 1000 ppm to about 1100 ppm, from about 1000 ppm to about 1200 ppm, from about 1000 ppm to about 1300 ppm, from about 1000 ppm to about 1400 ppm, from about 1000 ppm to about 1500 ppm, from about 1000 ppm to about 1600 ppm, from about 1000 ppm to about 1700 ppm, from about 1000 ppm to about 1800 ppm, from about 1000 ppm to about 1900 ppm, from about 1000 ppm to about 2000 ppm, from about 1100 ppm to about 1200 ppm, from about 1100 ppm to about 1300 ppm, from about 1100 ppm to about 1400 ppm, from about 1100 ppm to from about 1500 ppm, from about 1100 ppm to about 1600 ppm, from about 1100 ppm to about 1700 ppm, from about 1100 ppm to about 1800 ppm, from about 1100 ppm to about 1900 ppm, from about 1100 ppm to about 2000 ppm, from from about 1200 ppm to about 1300 ppm, from about 1200 ppm to about 1400 ppm, from about 1200 ppm to about 1500 ppm, from about 1200 ppm to about 1600 ppm, from about 1200 ppm to about 1700 ppm, from about 1200 ppm to about 1800 ppm, from about 1200 ppm to about 1900 ppm, from about 1200 ppm to about 2000 ppm, from about 1300 ppm to about 1400 ppm, from about 1300 ppm to about 1500 ppm, from about 1300 ppm to about 1600 ppm, from about 1300 ppm to about 1700 ppm, from about 1300 ppm to about 1800 ppm, from about 1300 ppm to about 1900 ppm, from about 1300 ppm to about 2000 ppm, from about 1400 ppm to about 1500 ppm, from about 1400 ppm to about 1600 ppm, from about 1400 ppm to about 1700 ppm, from about 1400 ppm to about 1800 ppm, from about 1400 ppm to about 1900 ppm, from about 1400 ppm to about 2000 ppm, from about 1500 ppm to about 1600 ppm, from about 1500 ppm to about 1700 ppm, from about 1500 ppm to about 1800 ppm, from about 1500 ppm to about 1900 ppm, from about 1500 ppm to about 2000 ppm, from about 1600 ppm to about 1700 ppm, from about 1600 ppm to about 1800 ppm , from about 1600 ppm to about 1900 ppm, from about 1600 ppm to about 2000 ppm, from about 1700 ppm to about 1800 ppm, from about 1700 ppm to about 1900 ppm, from about 1700 ppm to about 2000 ppm, from about 1800 ppm to about 1900 ppm, from about 1800 ppm to about 2000 ppm, or from about 1900 ppm to about 2000 ppm.

In aspects according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, about 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14 %, approximately 0.15%, approximately 0.16%, approximately 0.17%, approximately 0.18%, approximately 0.19%, approximately 0.2%, approximately 0.25%, approximately 0.3%, about 0.35%, about 0.4%, about 0.45%, or about 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, at least 0.10%, at least 0.11%, at least 0.12%, at least 0.13%, at least 0.14%, at least 0.15%, at least 0.16%, at least 0.17%, at least 0.18%, at least 0, 19%, at least 0.2%, at least 0.25%, at least 0.3%, at least 0.35%, at least 0.4%, at least 0.45% or at least 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount of, for example, no more than 0.10%, no more than 0.11%, no more than 0.12%, no more than 0.13% , no more than 0.14%, no more than 0.15%, no more than 0.16%, no more than 0.17%, no more than 0.18%, no more than 0.19%, no more than 0.2%, no more than 0.25%, no more than 0.3%, no more than 0.35%, no more than 0.4%, no more than 0.45% or no more than 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains free active chlorine in an amount, for example, from about 0.10% to about 0.15%, from about 0.10% to about 0.20%, from about 0.10% to about 0.25%, about 0.10% to about 0.30%, about 0.10% to about 0.35%, about 0.10% to about 0.40% , from about 0.10% to about 0.45%, from about 0.10% to about 0.50%, from about 0.20% to about 0.25%, from about 0.20% to about 0, 30%, from approx.

0.20% to about 0.35%, from about 0.20% to about 0.40%, from about 0.20% to about

0.45%, from about 0.20% to about 0.50%, from about 0.30% to about 0.35%, from about

0.30% to about 0.40%, from about 0.30% to about 0.45%, from about 0.30% to about

0.50%, from about 0.40% to about 0.45%, or from about 0.40% to about 0.50% by weight of the composition.

In one embodiment, the composition described in the present invention does not contain free active chlorine.

- 11 043933

In one embodiment, the composition described in the present invention does not contain ozone.

In another embodiment, the composition described in the present invention may contain ozone.

In one embodiment, the composition described in the present invention does not contain hydrogen peroxide. In another embodiment, the composition described in the present invention may contain hydrogen peroxide.

The composition described in the present invention may contain a quaternary compound. Non-limiting examples of quaternary compounds include a dialkyl quaternary and a fatty polyether quaternary. Examples of dialkyl quaternary compounds include, but are not limited to, didodecyldimethylammonium chloride and dialkyldimethylammonium chloride. The quaternary compound includes an organosilicon quaternary compound. Non-limiting examples of silicone quaternaries include silicone dialkyl quaternary and organosilicon fatty polyether quaternary. Examples of organosilicon dialkyl quaternary compounds include, but are not limited to, dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DTSACl) and tetradecyldimethyl-(3-trimethoxysilyl)propylammonium chloride (TTSACl). Examples of other quaternary compounds include, but are not limited to, a quaternary ammonium salt, such as, for example, Quaternium-15 and Quatemium-18, and a polycationic polymer, such as, for example, cetylpyridinium chloride, and polyquaterniums, such as Polyquaterniums 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46 and 47. Other non-limiting examples of quaternary compounds include compounds of the formula NR4+, where R represents an alkyl or aryl group.

In one embodiment, one quaternary compound or an organosilicon quaternary compound is present in the composition described in the present invention. In another embodiment, a plurality of quaternary compounds or organosilicon quaternary compounds are present in the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains, for example, one or more quaternary compounds or organosilicon quaternary compounds, two or more quaternary compounds or organosilicon quaternary compounds, three or more quaternary compounds or organosilicon quaternary compounds, four or more quaternary compounds or organosilicon quaternary compounds or five or more quaternary compounds or organosilicon quaternary compounds. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, only one quaternary compound or organosilicon quaternary compound, at least two quaternary compounds or organosilicon quaternary compounds, at least three quaternary compounds or organosilicon quaternary compounds, at least four quaternary compounds or organosilicon quaternary compounds or at least five quaternary compounds or organosilicon quaternary compounds. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, from 1 to 2 quaternary compounds or organosilicon quaternary compounds, from 1 to 3 quaternary compounds or organosilicon quaternary compounds, from 1 to 4 quaternary compounds or organosilicon quaternary compounds , from 1 to 5 quaternary compounds or organosilicon quaternary compounds, from 2 to 3 quaternary compounds or organosilicon quaternary compounds, from 2 to 4 quaternary compounds or organosilicon quaternary compounds, from 2 to 5 quaternary compounds or organosilicon quaternary compounds, from 3 to 4 quaternaries compounds or organosilicon quaternary compounds, from 3 to 5 quaternary compounds or organosilicon quaternary compounds or from 4 to 5 quaternary compounds or organosilicon quaternary compounds.

In one embodiment, the composition described in the present invention contains a quaternary compound or organosilicon quaternary compound in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm, 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm, 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm , 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1000 ppm, 1025 ppm, 1050 ppm, 1075 ppm, 1100 ppm, 1125 ppm, 1150 ppm, 1175 ppm, 1200 ppm, 1225 ppm, 1250 ppm, 1275 ppm, 1300 ppm, 1325 ppm, 1350 ppm, 1375 ppm, 1400 ppm, 1425 ppm, 1450 ppm, 1 475 ppm, 1500 ppm , 1600 ppm, 1700 ppm, 1800 ppm, 1900 ppm or 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, at least 0.05 ppm, at least 0.10 ppm, at least 0 .20 ppm, at least 0.30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0.90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1000 ppm, at least 1025 ppm, at least at least 1050 ppm, at least 1075 ppm, at least 1100 ppm, at least 1125 ppm, at least 1150 ppm, at least 1175 ppm, at least 1200 ppm, at least 1225 ppm, at least 1250 ppm, at least 1275 ppm, at least 1300 ppm, at least 1325 ppm, at least 1350 ppm, at least 1375 ppm, at least 1400 ppm, at least 1425 ppm, at least 1450 ppm, at least 1475 ppm, at least 1500 ppm, at least 1600 ppm, at least 1700 ppm, at least 1800 ppm, at least 1900 ppm or at least 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, no more than 0.05 ppm, no more than 0.10 ppm, no more than 0.20 ppm, no more than 0 ,30 ppm, no more than 0.40 ppm, no more than 0.50 ppm, no more than 0.60 ppm, no more than 0.70 ppm, no more than 0.80 ppm, no more than 0.90 ppm, no more than 1 ppm , no more than 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm, no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm , no more than 125 ppm, no more than 150 ppm, no more than 175 ppm, no more than 200 ppm, no more than 225 ppm, no more than 250 ppm, no more than 275 ppm, no more than 300 ppm, no more than 325 ppm, no more than 350 ppm , no more than 375 ppm, no more than 400 ppm, no more than 425 ppm, no more than 450 ppm, no more than 475 ppm, no more than 500 ppm, no more than 525 ppm, no more than 550 ppm, no more than 575 ppm, no more than 600 ppm , no more than 625 ppm, no more than 650 ppm, no more than 675 ppm, no more than 700 ppm, no more than 725 ppm, no more than 750 ppm, no more than 775 ppm, no more than 800 ppm, no more than 825 ppm, no more than 850 ppm , no more than 875 ppm, no more than 900 ppm, no more than 925 ppm, no more than 950 ppm, no more than 975 ppm, no more than 1000 ppm, no more than 1025 ppm, no more than 1050 ppm, no more than 1075 ppm, no more than 1100 ppm , no more

1125 ppm, no more than 1150 ppm, no more than 1175 ppm, no more than 1200 ppm, no more than 1225 ppm, no more

1250 ppm, no more than 1275 ppm, no more than 1300 ppm, no more than 1325 ppm, no more than 1350 ppm, no more

1375 ppm, not more than 1400 ppm, not more than 1425 ppm, not more than 1450 ppm, not more than 1475 ppm, not more than 1500 ppm, not more than 1600 ppm, not more than 1700 ppm, not more than 1800 ppm, not more than 1900 ppm or not more 2000 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, from about 0.5 ppm to about 20 ppm, from about 0.5 ppm to about 25 ppm, from about 0.5 ppm to about 30 ppm, from about 0.5 ppm to about 35 ppm, from about 0.5 ppm to about 40 ppm, from about 0.5 ppm to about 45 ppm, from about 0.5 ppm to about 50 ppm, from about 0.5 ppm to about 55 ppm, from about 0.5 ppm to about 60 ppm, from about 0.5 ppm to about 65 ppm, from about 0.5 ppm to about 70 ppm, from about 0 .5 ppm to about 75 ppm, from about 0.5 ppm to about 80 ppm, from about 0.5 ppm to about 85 ppm, from about 0.5 ppm to about 90 ppm, from about 0.5 ppm to about 95 ppm, from about 0.5 ppm to about 100 ppm, from about 0.75 ppm to about 20 ppm, from about 0.75 ppm to about 25 ppm, from about 0.75 ppm to about 30 ppm, from about 0. 75 ppm to about 35 ppm, from about 0.75 ppm to about 40 ppm, from about 0.75 ppm to about 45 ppm, from about 0.75 ppm to about 50 ppm, from about 0.75 ppm to about 55 ppm , from about 0.75 ppm to about 60 ppm, from about 0.75 ppm to about 65 ppm, from about 0.75 ppm to about 70 ppm, from about 0.75 ppm to about 75 ppm, from about 0.75 ppm to about 80 ppm, from about 0.75 ppm to about 85 ppm, from about 0.75 ppm to about 90 ppm, from about 0.75 ppm to about 95 ppm, from about 0.75 ppm to about 100 ppm, from about 1 ppm to about 20 ppm, from about 1 ppm to about 25 ppm, from about 1 ppm to about 30 ppm, from about 1 ppm to about 35 ppm, from about 1 ppm to about 40 ppm, from about 1 ppm to about 45 ppm, about 1 ppm to about 50 ppm, about 1 ppm to about 55 ppm, about 1 ppm to about 60 ppm, about 1 ppm to about 65 ppm, about 1 ppm to about

- 13 043933 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 80 ppm, from about 1 ppm to about 85 ppm, from about 1 ppm to about 90 ppm, from about 1 ppm to about 95 ppm, from about 1 ppm to about 100 ppm, from about 5 ppm to about 20 ppm, from about 5 ppm to about 25 ppm, from about 5 ppm to about 30 ppm, from about 5 ppm to about 35 ppm, from about 5 ppm to about 40 ppm, from about 5 ppm to about 45 ppm, from about 5 ppm to about 50 ppm, from about 5 ppm to about 55 ppm, from about 5 ppm to about 60 ppm, from about 5 ppm to about 65 ppm, from about 5 ppm to about 70 ppm, about 5 ppm to about 75 ppm, about 5 ppm to about 80 ppm, about 5 ppm to about 85 ppm, about 5 ppm to about 90 ppm, about 5 ppm to about 95 ppm, from about 5 ppm to about 100 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 35 ppm, from about 10 ppm to about 40 ppm, from about 10 ppm to about 45 ppm, from about 10 ppm to about 50 ppm, from about 10 ppm to about 55 ppm, from about 10 ppm to about 60 ppm, from about 10 ppm to about 65 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 85 ppm, from about 10 ppm to about 90 ppm, from about 10 ppm to about 95 ppm or from about 10 ppm to about 100 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount, for example, from about 1 ppm to about 25 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 100 ppm, from about 1 ppm to about 125 ppm, from about 1 ppm to about 150 ppm, from about 1 ppm to about 175 ppm, from about 1 ppm to about 200 ppm, from about 1 ppm to about 225 ppm, about 1 ppm to about 250 ppm, about 1 ppm to about 275 ppm, about 1 ppm to about 300 ppm, about 1 ppm to about 325 ppm, about 1 ppm to about 350 ppm, from about 1 ppm to about 375 ppm, from about 1 ppm to about 400 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 50 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 100 ppm, from about 10 ppm to about 125 ppm, from about 10 ppm to about 150 ppm, from about 10 ppm to about 175 ppm, from about 10 ppm to about 200 ppm, from about 10 ppm to about 225 ppm , from about 10 ppm to about 250 ppm, from about 10 ppm to about 275 ppm, from about 10 ppm to about 300 ppm, from about 10 ppm to about 325 ppm, from about 10 ppm to about 350 ppm, from about 10 ppm to about 375 ppm, from about 10 ppm to about 400 ppm, from about 25 ppm to about 50 ppm, from about 25 ppm to about 75 ppm, from about 25 ppm to about 100 ppm, from about 25 ppm to about 125 ppm, from about 25 ppm to about 150 ppm, from about 25 ppm to about 175 ppm, from about 25 ppm to about 200 ppm, from about 25 ppm to about 225 ppm, from about 25 ppm to about 250 ppm, from about 25 ppm to about 275 ppm, from about 25 ppm to about 300 ppm, from about 25 ppm to about 325 ppm, from about 25 ppm to about 350 ppm, from about 25 ppm to about 375 ppm, from about 25 ppm to about 400 ppm, from about 50 ppm to about 75 ppm, about 50 ppm to about 100 ppm, about 50 ppm to about 125 ppm, about 50 ppm to about 150 ppm, about 50 ppm to about 175 ppm, about 50 ppm to about 200 ppm, from about 50 ppm to about 225 ppm, from about 50 ppm to about 250 ppm, from about 50 ppm to about 275 ppm, from about 50 ppm to about 300 ppm, from about 50 ppm to about 325 ppm, from about 50 ppm to about 350 ppm, about 50 ppm to about 375 ppm, about 50 ppm to about 400 ppm, about 75 ppm to about 100 ppm, about 75 ppm to about 125 ppm, about 75 ppm to about 150 ppm, from about 75 ppm to about 175 ppm, from about 75 ppm to about 200 ppm, from about 75 ppm to about 225 ppm, from about 75 ppm to about 250 ppm, from about 75 ppm to about 275 ppm, from about 75 ppm to about 300 ppm, from about 75 ppm to about 325 ppm, from about 75 ppm to about 350 ppm, from about 75 ppm to about 375 ppm, from about 75 ppm to about 400 ppm, from about 100 ppm to about 125 ppm , from about 100 ppm to about 150 ppm, from about 100 ppm to about 175 ppm, from about 100 ppm to about 200 ppm, from about 100 ppm to about 225 ppm, from about 100 ppm to about 250 ppm, from about 100 ppm to about 275 ppm, from about 100 ppm to about 300 ppm, from about 100 ppm to about 325 ppm, from about 100 ppm to about 350 ppm, from about 100 ppm to about 375 ppm, from about 100 ppm to about 400 ppm, from about 150 ppm to about 175 ppm, from about 150 ppm to about 200 ppm, from about 150 ppm to about 225 ppm, from about 150 ppm to about 250 ppm, from about 150 ppm to about 275 ppm, from about 150 ppm to about 300 ppm, from about 150 ppm to about 325 ppm, from about 150 ppm to about 350 ppm, from about 150 ppm to about 375 ppm, from about 150 ppm to about 400 ppm, from about 200 ppm to about 225 ppm, from from about 200 ppm to about 250 ppm, from about 200 ppm to about 275 ppm, from about 200 ppm to about 300 ppm, from

- 14 043933 about 200 ppm to about 325 ppm, from about 200 ppm to about 350 ppm, from about 200 ppm to about 375 ppm, from about 200 ppm to about 400 ppm, from about 250 ppm to about 275 ppm, from about 250 ppm to about 300 ppm, from about 250 ppm to about 325 ppm, from about 250 ppm to about 350 ppm, from about 250 ppm to about 375 ppm, from about 250 ppm to about 400 ppm, from about 300 ppm to about 325 ppm , from about 300 ppm to about 350 ppm, from about 300 ppm to about 375 ppm, from about 300 ppm to about 400 ppm, from about 350 ppm to about 375 ppm, from about 350 ppm to about 400 ppm, or from about 375 ppm up to approximately 400 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, from about 400 ppm to about 500 ppm, from about 400 ppm to about 600 ppm, from about 400 ppm to about 700 ppm, from about 400 ppm to about 800 ppm, from about 400 ppm to about 900 ppm, from about 400 ppm to about 1000 ppm, from about 400 ppm to about 1100 ppm, from about 400 ppm to about 1200 ppm, from about 400 ppm to about 1300 ppm, from about 400 ppm to about 1400 ppm, from about 400 ppm to about 1500 ppm, from about 400 ppm to about 1600 ppm, from about 400 ppm to about 1700 ppm, from about 400 ppm to about 1800 ppm, from about 400 ppm to about 1900 ppm, from about 400 ppm to about 2000 ppm, from about 500 ppm to about 600 ppm, from about 500 ppm to about 700 ppm, from about 500 ppm to about 800 ppm, from about 500 ppm to about 900 ppm, from about 500 ppm to about 1000 ppm, from about 500 ppm to about 1100 ppm, from about 500 ppm to about 1200 ppm, from about 500 ppm to about 1300 ppm, from about 500 ppm to about 1400 ppm , from about 500 ppm to about 1500 ppm, from about 500 ppm to about 1600 ppm, from about 500 ppm to about 1700 ppm, from about 500 ppm to about 1800 ppm, from about 500 ppm to about 1900 ppm, from about 500 ppm to about 2000 ppm, from about 600 ppm to about 700 ppm, from about 600 ppm to about 800 ppm, from about 600 ppm to about 900 ppm, from about 600 ppm to about 1000 ppm, from about 600 ppm to about 1100 ppm, from about 600 ppm to about 1200 ppm, from about 600 ppm to about 1300 ppm, from about 600 ppm to about 1400 ppm, from about 600 ppm to about 1500 ppm, from about 600 ppm to about 1600 ppm, from about 600 ppm to about 1700 ppm, from about 600 ppm to about 1800 ppm, from about 600 ppm to about 1900 ppm, from about 600 ppm to about 2000 ppm, from about 700 ppm to about 800 ppm, from about 700 ppm to about 900 ppm, from from about 700 ppm to about 1000 ppm, from about 700 ppm to about 1100 ppm, from about 700 ppm to about 1200 ppm, from about 700 ppm to about 1300 ppm, from about 700 ppm to about 1400 ppm, from about 700 ppm to about 1500 ppm, from about 700 ppm to about 1600 ppm, from about 700 ppm to about 1700 ppm, from about 700 ppm to about 1800 ppm, from about 700 ppm to about 1900 ppm, from about 700 ppm to about 2000 ppm, from about 800 ppm to about 900 ppm, from about 800 ppm to about 1000 ppm, from about 800 ppm to about 1100 ppm, from about 800 ppm to about 1200 ppm, from about 800 ppm to about 1300 ppm, from about 800 ppm to about 1400 ppm, from about 800 ppm to about 1500 ppm, from about 800 ppm to about 1600 ppm, from about 800 ppm to about 1700 ppm, from about 800 ppm to about 1800 ppm, from about 800 ppm to about 1900 ppm, from about 800 ppm to about 2000 ppm, from about 900 ppm to about 1000 ppm, from about 900 ppm to about 1100 ppm, from about 900 ppm to about 1200 ppm, from about 900 ppm to about 1300 ppm, from about 900 ppm to about 1400 ppm , from about 900 ppm to about 1500 ppm, from about 900 ppm to about 1600 ppm, from about 900 ppm to about 1700 ppm, from about 900 ppm to about 1800 ppm, from about 900 ppm to about 1900 ppm, from about 900 ppm to about 2000 ppm, from about 1000 ppm to about 1100 ppm, from about 1000 ppm to about 1200 ppm, from about 1000 ppm to about 1300 ppm, from about 1000 ppm to about 1400 ppm, from about 1000 ppm to about 1500 ppm, from about 1000 ppm to about 1600 ppm, from about 1000 ppm to about 1700 ppm, from about 1000 ppm to about 1800 ppm, from about 1000 ppm to about 1900 ppm, from about 1000 ppm to about 2000 ppm, from about 1100 ppm to from about 1200 ppm, from about 1100 ppm to about 1300 ppm, from about 1100 ppm to about 1400 ppm, from about 1100 ppm to about 1500 ppm, from about 1100 ppm to about 1600 ppm, from about 1100 ppm to about 1700 ppm, from from about 1100 ppm to about 1800 ppm, from about 1100 ppm to about 1900 ppm, from about 1100 ppm to about 2000 ppm, from about 1200 ppm to about 1300 ppm, from about 1200 ppm to about 1400 ppm, from about 1200 ppm to about 1500 ppm, from about 1200 ppm to about 1600 ppm, from about 1200 ppm to about 1700 ppm, from about 1200 ppm to about 1800 ppm, from about 1200 ppm to about 1900 ppm, from about 1200 ppm to about 2000 ppm, from about 1300 ppm to about 1400 ppm, from about 1300 ppm to about 1500 ppm, from about 1300 ppm to about 1600 ppm, from about 1300 ppm to about 1700 ppm, from about 1300 ppm to about 1800 ppm, from about 1300 ppm to about 1900 ppm, from about 1300 ppm to about 2000 ppm, from about

- 15 043933

1400 ppm to about 1500 ppm, from about 1400 ppm to about 1600 ppm, from about 1400 ppm to about 1700 ppm, from about 1400 ppm to about 1800 ppm, from about 1400 ppm to about 1900 ppm, from about 1400 ppm to about 2000 ppm, from about 1500 ppm to about 1600 ppm, from about 1500 ppm to about 1700 ppm, from about 1500 ppm to about 1800 ppm, from about 1500 ppm to about 1900 ppm, from about 1500 ppm to about 2000 ppm, from about 1600 ppm to about 1700 ppm, from about 1600 ppm to about 1800 ppm, from about 1600 ppm to about 1900 ppm, from about 1600 ppm to about 2000 ppm, from about 1700 ppm to about 1800 ppm, from about 1700 ppm to about 1900 ppm , from about 1700 ppm to about 2000 ppm, from about 1800 ppm to about 1900 ppm, from about 1800 ppm to about 2000 ppm, or from about 1900 ppm to about 2000 ppm.

In aspects according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, about 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14%, approximately 0.15%, approximately 0.16%, approximately 0.17%, approximately 0.18%, approximately 0.19%, approximately 0.2%, approximately 0.25%, approximately 0. 3%, about 0.35%, about 0.4%, about 0.45%, or about 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, at least 0.10%, at least 0.11%, at least 0.12%, at least 0.13%, at least 0.14%, at least 0.15%, at least 0.16%, at least 0.17%, at least 0.18%, at least at least 0.19%, at least 0.2%, at least 0.25%, at least 0.3%, at least 0.35%, at least 0.4%, at least 0 .45% or at least 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, no more than 0.10%, no more than 0.11%, no more than 0.12%, no more than 0 ,13%, no more than 0.14%, no more than 0.15%, no more than 0.16%, no more than 0.17%, no more than 0.18%, no more than 0.19%, no more than 0, 2%, not more than 0.25%, not more than 0.3%, not more than 0.35%, not more than 0.4%, not more than 0.45% or not more than 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, from about 0.10% to about 0.15%, from about 0.10% to about 0.20 %, from about 0.10% to about 0.25%, from about 0.10% to about 0.30%, from about 0.10% to about 0.35%, from about 0.10% to about 0 .40%, from about 0.10% to about 0.45%, from about 0.10% to about 0.50%, from about 0.20% to about 0.25%, from about 0.20% to about 0.30%, from about 0.20% to about 0.35%, from about 0.20% to about 0.40%, from about 0.20% to about 0.45%, from about 0.20 % to about 0.50%, from about 0.30% to about 0.35%, from about 0.30% to about 0.40%, from about 0.30% to about 0.45%, from about 0 .30% to about 0.50%, from about 0.40% to about 0.45%, or from about 0.40% to about 0.50% by weight of the composition.

In aspects according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, about 1.0%, about 2.0%, about 3.0%, about 4.0%, about 5.0%, approximately 6.0%, approximately 7.0%, approximately 8.0%, approximately 9.0%, approximately 10%, approximately 11%, approximately 12%, approximately 13%, approximately 14% or approximately 15% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, at least 1.0%, at least 2.0%, at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0%, at least 7.0%, at least 8.0%, at least 9.0%, at least at least 10%, at least 11%, at least 12%, at least 13%, at least 14% or at least 15% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, no more than 1.0%, no more than 2.0%, no more than 3.0%, no more than 4 ,0%, no more than 5.0%, no more than 6.0%, no more than 7.0%, no more than 8.0%, no more than 9.0%, no more than 10%, no more than 11%, not more than 12%, no more than 13%, no more than 14% or no more than 15% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a quaternary compound or an organosilicon quaternary compound in an amount of, for example, from about 1.0% to about 2.0%, from about 1.0% to about 3.0 %, from about 1.0% to about 4.0%, from about 1.0% to about 5.0%, from about 1.0% to about 6.0%, from about 1.0% to about 7 .0%, from about 1.0% to about 8.0%, from about 1.0% to about 9.0%, from about 1.0% to about 10%, from about 1.0% to about 11 %, from about 1.0% to about 12%, from about 1.0% to about 13%, from about 1.0% to about 14%, from about 1.0% to about 15%, from about 2, 0% to about 3.0%, from about 2.0% to about 4.0%, from about 2.0% to about 5.0%, from about 2.0% to about 6.0%, from

- 16 043933 about 2.0% to about 7.0%, from about 2.0% to about 8.0%, from about 2.0% to about 9.0%, from about 2.0% to about 10 %, from about 2.0% to about 11%, from about 2.0% to about 12%, from about 2.0% to about 13%, from about 2.0% to about 14%, from about 2, 0% to about 15%, from about 3.0% to about 4.0%, from about 3.0% to about 5.0%, from about 3.0% to about 6.0%, from about 3, 0% to about 7.0%, from about 3.0% to about 8.0%, from about 3.0% to about 9.0%, from about 3.0% to about 10%, from about 3, 0% to about 11%, about 3.0% to about 12%, about 3.0% to about 13%, about 3.0% to about 14%, about 3.0% to about 15% , from about 4.0% to about 5.0%, from about 4.0% to about 6.0%, from about 4.0% to about 7.0%, from about 4.0% to about 8, 0%, from about 4.0% to about 9.0%, from about 4.0% to about 10%, from about 4.0% to about 11%, from about 4.0% to about 12%, from from about 4.0% to about 13%, from about 4.0% to about 14%, from about 4.0% to about 15%, from about 5.0% to about 6.0%, from about 5.0 % to about 7.0%, from about 5.0% to about 8.0%, from about 5.0% to about 9.0%, from about 5.0% to about 10%, from about 5.0 % to about 11%, from about 5.0% to about 12%, from about 5.0% to about 13%, from about 5.0% to about 14%, from about 5.0% to about 15%, from about 6.0% to about 7.0%, from about 6.0% to about 8.0%, from about 6.0% to about 9.0%, from about 6.0% to about 10%, from about 6.0% to about 11%, from about 6.0% to about 12%, from about 6.0% to about 13%, from about 6.0% to about 14%, from about 6.0% to about 15%, from about 7.0% to about 8.0%, from about 7.0% to about 9.0%, from about 7.0% to about 10%, from about 7.0% to about 11%, from about 7.0% to about 12%, from about 7.0% to about 13%, from about 7.0% to about 14%, from about 7.0% to about 15%, from about 8 .0% to about 9.0%, from about 8.0% to about 10%, from about 8.0% to about 11%, from about 8.0% to about 12%, from about 8.0% to about 13%, from about 8.0% to about 14%, from about 8.0% to about 15%, from about 9.0% to about 10%, from about 9.0% to about 11%, from about 9.0% to about 12%, about 9.0% to about 13%, about 9.0% to about 14%, about 9.0% to about 15%, about 10% to about 11% , from about 10% to about 12%, from about 10% to about 13%, from about 10% to about 14%, from about 10% to about 15%, from about 11% to about 12%, from about 11% to about 13%, from about 11% to about 14%, from about 11% to about 15%, from about 12% to about 13%, from about 12% to about 14%, from about 12% to about 15%, from about 13% to about 14%, from about 13% to about 15%, or from about 14% to about 15% by weight of the composition.

In one embodiment, the composition described in the present invention does not contain a quaternary compound. In one embodiment, the composition described in the present invention does not contain an organosilicon quaternary compound. In one embodiment, the composition described in the present invention does not contain a quaternary compound or an organosilicon quaternary compound.

The composition described in the present invention may contain a compound containing a guanide moiety and/or a functional group. Non-limiting examples of compounds containing a guanide moiety include an organic compound containing a biguanide functional group, a biguanidine functional group, or a triguanide functional group. In one embodiment, the guanide moiety-containing compound described herein is a biguanide or a compound containing a biguanide moiety. In one aspect, according to the specified embodiment, the compound containing the biguanide moiety contains one, two, three, four or five biguanide functional groups. In one aspect, according to this embodiment, the biguanide moiety-containing compound comprises formula II,

where each of R ⁵ and R ⁶ independently can represent a bond, H, C, NH, NH2, Ci ₀ alkyl, Ci ₀ alkane, Ci ₀ alkyne, a 5- or 6-membered aromatic ring, optionally substituted with halogen; and n is 1-5. Halogen represents F, Br, Cl, I and At. Non-limiting examples of compounds containing a biguanide moiety include polyhexamethylene biguanide (PHMB), polyaminopropyl biguanide (PAPB), 1,1'-(1,6-hexanediyl)bis{2-[N'-(2-ethylhexyl)carbamimidoyl]guanidine} (alexidine ), chlorhexidine and chlorhexidine gluconate.

In one embodiment, the guanide moiety-containing compound described herein is a biguanidine or a compound containing a biguanidine moiety. In one aspect, according to the specified embodiment, the compound containing the biguanidine moiety contains one, two, three, four or five biguanidine functional groups. In one aspect, according to this embodiment, the compound containing a biguanidine moiety comprises formula III,

where each of R ⁷ and R ⁸ independently can represent a bond, H, C, NH, NH2, Cyo alkyl, C _1-10 alkane, C1. ₁₀ alkyne, a 5- or 6-membered aromatic ring, optionally substituted with halogen; and n is 1-5. Halogen represents F, Br, Cl, I and At.

In one embodiment, the guanide moiety-containing compound described herein is a triguanide or a compound containing a triguanide moiety. In one aspect, according to this embodiment, the triguanide moiety-containing compound contains one, two, three, four, or five triguanide functional groups. In one aspect, according to this embodiment, the triguanide moiety-containing compound comprises formula IV,

where each of R ⁹ and R ¹⁰ can independently represent a bond, H, C, NH, NH2, C1. ₁₀ alkyl, C1. ₁₀ alkane, C1.10 alkyne, 5- or 6-membered aromatic ring, optionally substituted with halogen; and n is 1-5. Halogen represents F, Br, Cl, I and At.

In one embodiment, the composition described in the present invention contains a single compound containing a guanide moiety. In another embodiment, the composition described in the present invention contains a plurality of compounds containing a guanide moiety. In aspects according to this embodiment, the composition described in the present invention contains, for example, one or more compounds containing a guanide moiety, two or more compounds containing a guanide moiety, three or more compounds containing a guanide moiety, four or more compounds containing guanide moiety, or five or more compounds containing a guanide moiety. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, only one compound containing a guanide moiety, no more than two compounds containing a guanide moiety, no more than three compounds containing a guanide moiety, no more than four compounds containing guanide moiety, or up to five compounds containing a guanide moiety. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, from 1 to 2 compounds containing a guanide moiety, from 1 to 3 compounds containing a guanide moiety, from 1 to 4 compounds containing a guanide moiety, from 1 up to 5 compounds containing a guanide fragment, from 2 to 3 compounds containing a guanide fragment, from 2 to 4 compounds containing a guanide fragment, from 2 to 5 compounds containing a guanide fragment, from 3 to 4 compounds containing a guanide fragment, from 3 up to 5 compounds containing a guanide moiety, or 4 to 5 compounds containing a guanide moiety.

Any amount of a guanide moiety-containing compound described herein may be used, provided that the amount is suitable for use in the methods described herein. In aspects according to this embodiment, the composition described in the present invention contains a compound containing a guanide moiety in an amount of, for example, about 0.01%, about 0.05%, about 0.075%, about 0.1%, about 0. 2%, approximately 0.3%, approximately 0.4%, approximately 0.5%, approximately 0.6%, approximately 0.7%, approximately 0.8%, approximately 0.9%, approximately 1.0% , approximately 1.5%, approximately 2.0%, approximately 2.5%, approximately 3.0%, approximately 4.0%, approximately 5.0%, approximately 6.0%, approximately 7.0%, approximately 7.5%, approximately 8.0%, approximately 9.0%, approximately 10.0%, approximately 11%, approximately 12%, approximately 13%, approximately 14%, approximately 15%, approximately 20%, approximately 25% or about 30% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a compound containing a guanide moiety in an amount of, for example, at least 0.01%, at least 0.05%, at least 0.075%, at least at least 0.1%, at least 0.25%, at least 0.5%, at least 0.75%, at least 1.0%, at least 1.5%, at least 2 .0%, at least

- 18 043933

2.5%, at least 3.0%, at least 4.0%, at least 5.0%, at least 6.0%, at least 7.0%, at least 7, 5%, at least 8.0%, at least 9.0%, at least 10.0%, at least 11%, at least 12%, at least 13%, at least 14% , at least 15%, at least 20%, at least 25% or at least 30% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a compound containing a guanide moiety in an amount of, for example, no more than 0.01%, no more than 0.05%, no more than 0.075%, no more than 0.1 %, no more than 0.25%, no more than 0.5%, no more than 0.75%, no more than 1.0%, no more than 1.5%, no more than 2.0%, no more than 2.5% , no more than 3.0%, no more than 4.0%, no more than 5.0%, no more than 6.0%, no more than 7.5%, no more than 8.0%, no more than 9.0%, no more than 10.0%, no more than 11%, no more than 12%, no more than 13%, no more than 14%, no more than 15%, no more than 20%, no more than 25% or no more than 30% by weight of the composition.

In other aspects, according to this embodiment, the composition described in the present invention contains a compound containing a guanide moiety in an amount of, for example, from about 0.1% to about 0.5%, from about 0.1% to about 0.75 %, from about 0.1% to about 1.0%, from about 0.1% to about 1.5%, from about 0.1% to about 2.0%, from about 0.1% to about 2 .5%, from about 0.1% to about 3.0%, from about 0.1% to about 3.5%, from about 0.1% to about 4.0%, from about 0.1% to about 4.5%, about 0.1% to about 5.0%, about 0.2% to about 0.5%, about 0.2% to about 0.75%, about 0.2 % to about 1.0%, from about 0.2% to about 1.5%, from about 0.2% to about 2.0%, from about 0.2% to about 2.5%, from about 0 .2% to about 3.0%, from about 0.2% to about 3.5%, from about 0.2% to about 4.0%, from about 0.2% to about 4.5%, from about 0.2% to about 5.0%, about 0.5% to about 1.0%, about 0.5% to about 1.5%, about 0.5% to about 2.0% , from about 0.5% to about 2.5%, from about 0.5% to about 3.0%, from about 0.5% to about 4.0%, from about 0.5% to about 5, 0%, from about 0.5% to about 6.0%, from about 0.5% to about 7.0%, from about 0.5% to about 8.0%, from about 0.5% to about 9.0%, from about 0.5% to about 10.0%, from about 1.0% to about 2.5%, from about 1.0% to about 3.0%, from about 1.0% to about 4.0%, from about 1.0% to about 5.0%, from about 1.0% to about 6.0%, from about 1.0% to about 7.0%, from about 1, 0% to about 7.5%, from about 1.0% to about 8.0%, from about 1.0% to about 9.0%, from about 1.0% to about 10.0%, from about 1.0% to about 15.0%, from about 1.0% to about 20.0%, from about 1.0% to about 25.0%, from about 1.0% to about 30.0%, from about 2.0% to about 2.5%, from about 2.0% to about 3.0%, from about 2.0% to about 4.0%, from about 2.0% to about 5.0 %, from about 2.0% to about 6.0%, from about 2.0% to about 7.0%, from about 2.0% to about 7.5%, from about 2.0% to about 8 .0%, from about 2.0% to about 9.0%, from about 2.0% to about 10.0%, from about 2.0% to about 15.0%, from about 2.0% to about 20.0%, about 2.0% to about 25.0%, about 2.0% to about 30.0%, about 5.0% to about 6.0%, about 5.0 % to about 7.0%, from about 5.0% to about 7.5%, from about 5.0% to about 8.0%, from about 5.0% to about 9.0%, from about 5 .0% to about 10.0%, from about 5.0% to about 11.0%, from about 5.0% to about 12.0%, from about 5.0% to about 13.0%, from about 5.0% to about 14.0%, about 5.0% to about 15.0%, about 5.0% to about 20.0%, about 5.0% to about 25.0% , from about 5.0% to about 30.0%, from about 10.0% to about 15.0%, from about 10.0% to about 20.0%, from about 10.0% to about

25.0%, from about 10.0% to about 30.0%, from about 15.0% to about 20.0%, from about

15.0% to about 25.0%, from about 15.0% to about 30.0%, from about 20.0% to about

25.0%, from about 20.0% to about 30.0%, or from about 20.0% to about 30.0% by weight of the composition.

In another embodiment, the composition described in the present invention does not contain a compound containing a guanide moiety. In another embodiment, the composition described in the present invention does not contain a biguanide. In another embodiment, the composition described in the present invention does not contain a compound containing a biguanide moiety. In another embodiment, the composition described in the present invention does not contain biguanidine. In another embodiment, the composition described in the present invention does not contain a compound containing a biguanidine moiety. In another embodiment, the composition described in the present invention does not contain triguanide. In another embodiment, the composition described in the present invention does not contain a compound containing a triguanide moiety.

The composition described in the present invention may contain alcohol. An alcohol is an organic molecule containing a hydroxyl functional group (-OH) bonded to a carbon atom, where the carbon atom is saturated. In aspects of this embodiment, _the alcohol may be, for example, a _C2-4 alcohol, a _{C1_4} alcohol, a _{C1_5} alcohol, a C1_7 alcohol, a _hundred alcohol, a C1-15 alcohol, or a _C1-2o alcohol. In other aspects, according to this embodiment, the alcohol may be, for example, a primary alcohol, a secondary alcohol, or a tertiary alcohol. In other aspects, according to this embodiment, the alcohol may be, for example,

- 19 043933 acyclic alcohol, monohydric alcohol, polyhydric alcohol (also known as polyol or sugar alcohol), unsaturated aliphatic alcohol, alicyclic alcohol or a combination thereof. Examples of monohydric alcohols include, but are not limited to, methanol, ethanol, propanol, isopropanol, butanol, pentanol, and 1-hexadecanol. Examples of polyhydric alcohols include, but are not limited to, glycol, glycerin, arabitol, erythritol, xylitol, maltitol, sorbitol (glucite), mannitol, inositol, lactitol, galactitol (iditol), and isomalt. Examples of unsaturated aliphatic alcohols include, but are not limited to, prop-2-en-1-ol, 3,7dimethylocta-2,6-dien-1-ol, and prop-2-yn-1-ol. Examples of alicyclic alcohols include, but are not limited to, cyclohexane-1,2,3,4,5,6-hexol and 2-(2-propyl)-5-methylcyclohexan-1-ol.

In one embodiment, the composition described in the present invention contains one alcohol. In another embodiment, the composition described in the present invention contains a plurality of alcohols. In aspects according to this embodiment, the composition described in the present invention contains, for example, one or more alcohols, two or more alcohols, three or more alcohols, four or more alcohols, or five or more alcohols. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, only one alcohol, no more than two alcohols, no more than three alcohols, no more than four alcohols, or no more than five alcohols. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, from 1 to 2 alcohols, from 1 to 3 alcohols, from 1 to 4 alcohols, from 1 to 5 alcohols, from 2 to 3 alcohols, from 2 up to 4 alcohols, from 2 to 5 alcohols, from 3 to 4 alcohols, from 3 to 5 alcohols or from 4 to 5 alcohols.

In aspects according to this embodiment, the plurality of alcohols contained in the composition described in the present invention may be, for example, about 99% of the first alcohol and about 1% of the second alcohol, about 98% of the first alcohol and about 2% of the second alcohol, about 97% first alcohol and about 3% second alcohol, about 96% first alcohol and about 4% second alcohol, about 95% first alcohol and about 5% second alcohol, about 90% first alcohol and about 10% second alcohol, about 80% first alcohol and about 20% second alcohol, about 70% first alcohol and about 30% second alcohol, about 60% first alcohol and about 40% second alcohol, about 50% first alcohol and about 50% second alcohol, about 40% first alcohol and about 60% second alcohol, about 30% first alcohol and about 70% second alcohol, about 20% first alcohol and about 80% second alcohol, about 10% first alcohol and about 90% second alcohol, about 5% first alcohol and about 95% second alcohol. In other aspects, according to this embodiment, the ratio of the first alcohol to the second alcohol is, for example, 100:1, 90:1, 80:1, 70:1, 60:1, 50:1, 40:1, 30:1, 20 :1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1 , 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1 :7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19 , 1:20, 1:30, 1:40, 1:50, 1:60, 1:70, 1:80, 1:90 or 1:100. In other aspects, the first alcohol is isopropanol and the second alcohol is ethanol.

Any amount of the alcohol described in the present invention can be used, provided that the amount is suitable for the use of the methods described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains alcohol in an amount of, for example, about 0.5%, about 1%, about 2%, about 3%, about 4%, about 5%, about 6%, approximately 7%, approximately 8%, approximately 9%, approximately 10%, approximately 11%, approximately 12%, approximately 13%, approximately 14%, approximately 15%, approximately 20%, approximately 25%, approximately 30%, approximately 35 %, approximately 40%, approximately 45%, approximately 50%, approximately 55%, approximately 60%, approximately 65%, approximately 70%, approximately 75%, approximately 80%, approximately 85%, approximately 90%, approximately 95%, about 96%, about 97%, about 98%, or about 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains alcohol in an amount of, for example, at least 0.5%, at least 1%, at least 2%, at least 3%, at least 4%, at least 5%, at least 6%, at least 7%, at least 8%, at least 9%, at least 10%, at least 11%, at least 12% , at least 13%, at least 14%, at least 15%, at least 20%, at least 25%, at least 30%, at least 35%, at least 40%, according to at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains alcohol in an amount of, for example, no more than 0.5%, no more than 1%, no more than 2%, no more than 3%, no more than 4%, no more 5%, no more than 6%, no more than 7%, no more than 8%, no more than 9%, no more than 10%, no more than 11%, no more than 12%, no more than 13%, no more than 14%, no more 15%, no more than 20%, no more than 25%, no more than 30%, no more than 35%, no more than 40%, no more than 45%, no more than 50%, no more than 55%, no more than 60%, no more 65%, no more than 70%, no more than 75%, no more than 80%, no more than 85%, no more than 90%, no more than 95%, no more than 96%, no more than 97%, no more than 98% or no more 99% by weight of the composition.

In other aspects, according to this embodiment, the composition described herein

- 20 043933 invention, contains alcohol in an amount, for example, from about 0.05% to about 0.75%, from about 0.05% to about 1.0%, from about 0.05% to about 1.5% , from about 0.05% to about 2.0%, from about 0.05% to about 2.5%, from about 0.1% to about 0.5%, from about 0.1% to about 0, 75%, about 0.1% to about 1.0%, about 0.1% to about 1.5%, about 0.1% to about 2.0%, about 0.1% to about 2.5%, from about 0.1% to about 3.0%, from about 0.1% to about 4.0%, from about 0.1% to about 5.0%, from about 0.2% to about 0.5%, from about 0.2% to about 0.75%, from about 0.2% to about 1.0%, from about 0.2% to about 1.5%, from about 0. 2% to about 2.0%, from about 0.2% to about 2.5%, from about 0.2% to about 3.0%, from about 0.2% to about 4.0%, from about 0.2% to about 5.0%, from about 0.5% to about 1.0%, from about 0.5% to about 1.5%, from about 0.5% to about 2.0%, from about 0.5% to about 2.5%, from about 0.5% to about 3.0%, from about 0.5% to about 4.0%, from about 0.5% to about 5.0 %, from about 0.5% to about 6.0%, from about 0.5% to about 7.0%, from about 0.5% to about 8.0%, from about 0.5% to about 9 .0%, from about 0.5% to about 10.0%, from about 1.0% to about 2.5%, from about 1.0% to about 3.0%, from about 1.0% to about 4.0%, about 1.0% to about 5.0%, about 1.0% to about 6.0%, about 1.0% to about 7.0%, about 1.0 % to about 7.5%, from about 1.0% to about 8.0%, from about 1.0% to about 9.0%, from about 1.0% to about 10.0%, from about 2 .0% to about 2.5%, from about 2.0% to about 3.0%, from about 2.0% to about 4.0%, from about 2.0% to about 5.0%, from about 2.0% to about 6.0%, about 2.0% to about 7.0%, about 2.0% to about 7.5%, about 2.0% to about 8.0% , from about 2.0% to about 9.0%, from about 2.0% to about 10.0%, from about 5.0% to about 6.0%, from about 5.0% to about 7, 0%, from about 5.0% to about 7.5%, from about 5.0% to about 8.0%, from about 5.0% to about 9.0%, from about 5.0% to about 10.0%, from about 5.0% to about 11.0%, from about 5.0% to about 12.0%, from about 5.0% to about 13.0%, from about 5.0% to about 14.0%, or from about 5.0% to about 15.0% by weight of the composition, or from about 10% to about 20%, from about 10% to about 30%, from about 10% to about 40% , from about 10% to about 50%, from about 10% to about 60%, from about 10% to about 70%, from about 10% to about 80%, from about 10% to about 90%, from about 10% to about 95%, from about 10% to about 97%, from about 10% to about 99%, from about 20% to about 30%, from about 20% to about 40%, from about 20% to about 50%, from about 20% to about 60%, from about 20% to about 70%, from about 20% to about 80%, from about 20% to about 90%, from about 20% to about 95%, from about 20% to about 97%, from about 20% to about 99%, from about 30% to about 40%, from about 30% to about 50%, from about 30% to about 60%, from about 30% to about 70%, from about 30% to about 80%, about 30% to about 90%, about 30% to about 95%, about 30% to about 97%, about 30% to about 99%, about 40% to about 50%, from about 40% to about 60%, from about 40% to about 70%, from about 40% to about 80%, from about 40% to about 90%, from about 40% to about 95%, from about 40% to about 97%, from about 40% to about 99%, from about 50% to about 60%, from about 50% to about 70%, from about 50% to about 80%, from about 50% to about 90 %, from about 50% to about 95%, from about 50% to about 97%, from about 50% to about 99%, from about 60% to about 70%, from about 60% to about 80%, from about 60 % to about 90%, from about 60% to about 95%, from about 60% to about 97%, from about 60% to about 99%, from about 70% to about 80%, from about 70% to about 90% , from about 70% to about 95%, from about 70% to about 97%, from about 70% to about 99%, from about 80% to about 90%, from about 80% to about 95%, from about 80% to about 97%, from about 80% to about 99%, from about 90% to about 95%, from about 90% to about 97%, from about 90% to about 99% by weight of the composition.

In aspects according to this embodiment, the composition described in the present invention contains a plurality of alcohols in a total amount, for example, about 10%, about 15%, about 20%, about 25%, about 30%, about 35%, about 40%, about 45%, about 50%, about 55%, about 60%, about 65%, about 70%, about 75%, about 80%, about 85%, about 90%, about 95%, about 96%, about 97 %, about 98% or about 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a plurality of alcohols in a total amount, for example, at least 10%, at least 15%, at least 20%, at least 25%, at least 30%, at least 35%, at least 40%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least 70% , at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or according at least 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a plurality of alcohols in a total amount, for example, not more than 10%, not

- 21 043933 more than 15%, no more than 20%, no more than 25%, no more than 30%, no more than 35%, no more than 40%, no more than 45%, no more than 50%, no more than 55%, no more than 60 %, no more than 65%, no more than 70%, no more than 75%, no more than 80%, no more than 85%, no more than 90%, no more than 95%, no more than 96%, no more than 97%, no more than 98 % or not more than 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a plurality of alcohols in a total amount, for example, from about 10% to about 20%, from about 10% to about 30%, from about 10% to about 40%, from about 10% to about 50%, from about 10% to about 60%, from about 10% to about 70%, from about 10% to about 80%, from about 10% to about 90%, from about 10% to about 95%, from about 10% to about 97%, from about 10% to about 99%, from about 20% to about 30%, from about 20% to about 40%, from about 20% to about 50%, from about 20% to about 60%, about 20% to about 70%, about 20% to about 80%, about 20% to about 90%, about 20% to about 95%, about 20% to about 97%, from about 20% to about 99%, from about 30% to about 40%, from about 30% to about 50%, from about 30% to about 60%, from about 30% to about 70%, from about 30% to about 80%, from about 30% to about 90%, from about 30% to about 95%, from about 30% to about 97%, from about 30% to about 99%, from about 35% to about 40 %, from about 35% to about 50%, from about 35% to about 60%, from about 35% to about 70%, from about 35% to about 80%, from about 35% to about 90%, from about 35 % to about 95%, from about 35% to about 97%, from about 35% to about 99%, from about 40% to about 50%, from about 40% to about 60%, from about 40% to about 70% , from about 40% to about 80%, from about 40% to about 90%, from about 40% to about 95%, from about 40% to about 97%, from about 40% to about 99%, from about 45% to about 50%, from about 45% to about 60%, from about 45% to about 70%, from about 45% to about 80%, from about 45% to about 90%, from about 45% to about 95%, from about 45% to about 97%, from about 45% to about 99%, from about 50% to about 60%, from about 50% to about 70%, from about 50% to about 80%, from about 50% to about 90%, from about 50% to about 95%, from about 50% to about 97%, from about 50% to about 99%, from about 60% to about 70%, from about 60% to about 80%, from about 60% to about 90%, about 60% to about 95%, about 60% to about 97%, about 60% to about 99%, about 70% to about 80%, about 70% to about 90%, from about 70% to about 95%, from about 70% to about 97%, from about 70% to about 99%, from about 80% to about 90%, from about 80% to about 95%, from about 80% to about 97%, from about 80% to about 99%, from about 90% to about 95%, from about 90% to about 97%, from about 90% to about 99% by weight of the composition.

In another embodiment, the composition described in the present invention does not contain alcohol.

The composition described in the present invention may contain metal particles. The metal particle may be composed of a single element, such as, for example, copper, iron, silver, titanium or zinc, or may be a mixed metal particle consisting of various combinations of different elements, such as, for example, various combinations of two or more of the following elements: copper, iron, silver, titanium or zinc. Non-limiting examples of metal particles include a copper particle, an iron particle, a potassium particle, a silver particle, a titanium particle, and a zinc particle. Other non-limiting examples of metal particles include a metal acetate particle, a metal chloride particle, a metal nitrate particle, or a metal oxide particle. Metal acetate particles include, but are not limited to, copper acetate, iron acetate, such as iron(II) acetate and iron(III) acetate, silver acetate, titanium acetate, zinc acetate, or any combination thereof. Metal nitrate particles include, but are not limited to, copper nitrate, iron nitrate, such as iron(II) nitrate, iron(III) nitrate, silver nitrate, titanium nitrate, zinc nitrate, or any combination thereof. Metal chloride particles include, but are not limited to, copper chloride, ferric chloride, such as ferric (II) chloride or ferric (III) chloride, silver chloride, titanium chloride, zinc chloride, or any combination thereof. The metal oxide particles include, but are not limited to, copper oxide, iron oxide, such as iron(II) oxide, iron(III) oxide, silver oxide, titanium oxide, zinc oxide, mixed copper-zinc-iron oxide, or any combination thereof.

Metal particles include nanoparticles and microparticles. Nanoparticles have an average diameter from about 1 nm to about 1000 nm. The microparticles have an average diameter of from about 1 μm to about 1000 μm.

In one embodiment, the composition described in the present invention contains metal particles in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm , 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm , 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm,

- 22 043933 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm , 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm, 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1000 ppm, 1025 ppm, 1050 ppm, 1075 ppm, 1100 ppm, 1125 ppm, 1150 ppm, 1175 ppm, 1200 ppm, 1225 ppm, 1250 ppm, 1275 ppm, 1300 ppm, 1325 ppm 1350 ppm, 1375 ppm, 1400 ppm, 1425 ppm, 1450 ppm, 1475 ppm, 1500 ppm, 1600 ppm, 1700 ppm, 1800 ppm, 1900 ppm or 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0 .30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least 0.80 ppm, at least 0.90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least 200 ppm, at least 225 ppm, at least at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm, at least 825 ppm, at least 850 ppm, at least at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1000 ppm, at least 1025 ppm, at least 1050 ppm, at least 1075 ppm, at least 1100 ppm, at least 1125 ppm, at least 1150 ppm, at least 1175 ppm, at least 1200 ppm, at least 1225 ppm, at least 1250 ppm, at least 1275 ppm, at least 1300 ppm, at least 1325 ppm, at least 1350 ppm, at least 1375 ppm, at least 1400 ppm, at least 1425 ppm, at least 1450 ppm, at least 1475 ppm, at least at least 1500 ppm, at least 1600 ppm, at least 1700 ppm, at least 1800 ppm, at least 1900 ppm or at least 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, no more than 0.05 ppm, no more than 0.10 ppm, no more than 0.20 ppm, no more than 0.30 ppm, no more than 0.40 ppm, no more than 0.50 ppm, no more than 0.60 ppm, no more than 0.70 ppm, no more than 0.80 ppm, no more than 0.90 ppm, no more than 1 ppm, no more than 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm, no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm, no more than 125 ppm, no more than 150 ppm, no more than 175 ppm, no more than 200 ppm, no more than 225 ppm, no more than 250 ppm, no more than 275 ppm, no more than 300 ppm, no more than 325 ppm, no more than 350 ppm, no more than 375 ppm, no more than 400 ppm, no more than 425 ppm, no more than 450 ppm, no more than 475 ppm, no more than 500 ppm, no more than 525 ppm, no more than 550 ppm, no more than 575 ppm, no more than 600 ppm, no more than 625 ppm, no more than 650 ppm, no more than 675 ppm, no more than 700 ppm, no more than 725 ppm, no more than 750 ppm, no more than 775 ppm, no more than 800 ppm, no more than 825 ppm, no more than 850 ppm, no more than 875 ppm, no more than 900 ppm, no more than 925 ppm, no more than 950 ppm, no more than 975 ppm, no more than 1000 ppm, no more than 1025 ppm, no more than 1050 ppm, no more than 1075 ppm, no more than 1100 ppm, no more than 1125 ppm, no more than 1150 ppm, no more than 1175 ppm, no more than 1200 ppm, no more than 1225 ppm, no more than 1250 ppm, no more than 1275 ppm, no more than 1300 ppm, no more than 1325 ppm, no more than 1350 ppm, no more than 1375 ppm, not more than 1400 ppm, not more than 1425 ppm, not more than 1450 ppm, not more than 1475 ppm, not more than 1500 ppm, not more than 1600 ppm, not more than 1700 ppm, not more than 1800 ppm, not more than 1900 ppm or not more than 2000 ppm

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount, for example, from about 0.5 ppm to about 20 ppm, from about 0.5 ppm to about 25 ppm, from about 0.5 ppm to about 30 ppm, from about 0.5 ppm to about 35 ppm, from about 0.5 ppm to about 40 ppm, from about 0.5 ppm to about 45 ppm, from about 0.5 ppm to about 50 ppm, from about 0.5 ppm to about 55 ppm, about 0.5 ppm to about 60 ppm, about 0.5 ppm to about 65 ppm, about 0.5 ppm to about 70 ppm, about 0.5 ppm to about 75 ppm, from about 0.5 ppm to about 80 ppm, from about 0.5 ppm to about 85 ppm, from about 0.5 ppm to about 90 ppm, from about 0.5 ppm to about 95 ppm, from about 0.5 ppm to about 100 ppm, from about 0.75 ppm to about 20 ppm, from about 0.75 ppm to about 25 ppm, from about 0.75 ppm to about 30 ppm, from about 0.75 ppm to about 35 ppm, from about 0.75 ppm to about 40 ppm, from about 0.75 ppm to about 45 ppm, from about 0.75 ppm to about 50 ppm, from about 0.75 ppm to about 55 ppm, from about 0 .75 ppm to about 60 ppm, from about 0.75 ppm to about 65 ppm, from about 0.75 ppm to about 70 ppm, from about 0.75 ppm to about 75 ppm, from at

- 23 043933 approximately 0.75 ppm to approximately 80 ppm, from approximately 0.75 ppm to approximately 85 ppm, from approximately 0.75 ppm to approximately 90 ppm, from approximately 0.75 ppm to approximately 95 ppm, from approximately 0, 75 ppm to about 100 ppm, about 1 ppm to about 20 ppm, about 1 ppm to about 25 ppm, about 1 ppm to about 30 ppm, about 1 ppm to about 35 ppm, about 1 ppm to about 40 ppm, from about 1 ppm to about 45 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 55 ppm, from about 1 ppm to about 60 ppm, from about 1 ppm to about 65 ppm, from about 1 ppm to about 70 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 80 ppm, from about 1 ppm to about 85 ppm, from about 1 ppm to about 90 ppm, from about 1 ppm to about 95 ppm , from about 1 ppm to about 100 ppm, from about 5 ppm to about 20 ppm, from about 5 ppm to about 25 ppm, from about 5 ppm to about 30 ppm, from about 5 ppm to about 35 ppm, from about 5 ppm to about 40 ppm, from about 5 ppm to about 45 ppm, from about 5 ppm to about 50 ppm, from about 5 ppm to about 55 ppm, from about 5 ppm to about 60 ppm, from about 5 ppm to about 65 ppm, from about 5 ppm to about 70 ppm, from about 5 ppm to about 75 ppm, from about 5 ppm to about 80 ppm, from about 5 ppm to about 85 ppm, from about 5 ppm to about 90 ppm, from about 5 ppm to about 95 ppm, from about 5 ppm to about 100 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 35 ppm, from about 10 ppm to about 40 ppm, about 10 ppm to about 45 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 55 ppm, about 10 ppm to about 60 ppm, about 10 ppm to about 65 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 85 ppm, from about 10 ppm to about 90 ppm, from about 10 ppm to about 95 ppm or from about 10 ppm to about 100 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount, for example, from about 1 ppm to about 25 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 100 ppm, about 1 ppm to about 125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, from about 1 ppm to about 250 ppm, from about 1 ppm to about 275 ppm, from about 1 ppm to about 300 ppm, from about 1 ppm to about 325 ppm, from about 1 ppm to about 350 ppm, from about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, from about 10 ppm to about 125 ppm, from about 10 ppm to about 150 ppm, from about 10 ppm to about 175 ppm, from about 10 ppm to about 200 ppm, from about 10 ppm to about 225 ppm, from about 10 ppm to about 250 ppm, from about 10 ppm to about 275 ppm, from about 10 ppm to about 300 ppm, from about 10 ppm to about 325 ppm, from about 10 ppm to about 350 ppm, from about 10 ppm to about 375 ppm , from about 10 ppm to about 400 ppm, from about 25 ppm to about 50 ppm, from about 25 ppm to about 75 ppm, from about 25 ppm to about 100 ppm, from about 25 ppm to about 125 ppm, from about 25 ppm to about 150 ppm, from about 25 ppm to about 175 ppm, from about 25 ppm to about 200 ppm, from about 25 ppm to about 225 ppm, from about 25 ppm to about 250 ppm, from about 25 ppm to about 275 ppm, from about 25 ppm to about 300 ppm, from about 25 ppm to about 325 ppm, from about 25 ppm to about 350 ppm, from about 25 ppm to about 375 ppm, from about 25 ppm to about 400 ppm, from about 50 ppm to about 75 ppm, from about 50 ppm to about 100 ppm, from about 50 ppm to about 125 ppm, from about 50 ppm to about 150 ppm, from about 50 ppm to about 175 ppm, from about 50 ppm to about 200 ppm, from about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, from about 50 ppm to about 375 ppm, from about 50 ppm to about 400 ppm, from about 75 ppm to about 100 ppm, from about 75 ppm to about 125 ppm, from about 75 ppm to about 150 ppm, from about 75 ppm to about 175 ppm, about 75 ppm to about 200 ppm, about 75 ppm to about 225 ppm, about 75 ppm to about 250 ppm, about 75 ppm to about 275 ppm, about 75 ppm to about 300 ppm, from about 75 ppm to about 325 ppm, from about 75 ppm to about 350 ppm, from about 75 ppm to about 375 ppm, from about 75 ppm to about 400 ppm, from about 100 ppm to about 125 ppm, from about 100 ppm to about 150 ppm, from about 100 ppm to about 175 ppm, from about 100 ppm to about 200 ppm, from about 100 ppm to about 225 ppm, from about 100 ppm to about 250 ppm, from about 100 ppm to about 275 ppm , from about 100 ppm to about 300 ppm, from about 100 ppm to about 325 ppm, from about 100 ppm to about 350 ppm, from about 100 ppm to about 375 ppm, from about 100 ppm to about 400 ppm, from about 150 ppm to about 175 ppm, from about 150 ppm to about

- 24 043933

200 ppm, from about 150 ppm to about 225 ppm, from about 150 ppm to about 250 ppm, from about 150 ppm to about 275 ppm, from about 150 ppm to about 300 ppm, from about 150 ppm to about 325 ppm, from about 150 ppm to about 350 ppm, from about 150 ppm to about 375 ppm, from about 150 ppm to about 400 ppm, from about 200 ppm to about 225 ppm, from about 200 ppm to about 250 ppm, from about 200 ppm to about 275 ppm, from about 200 ppm to about 300 ppm, from about 200 ppm to about 325 ppm, from about 200 ppm to about 350 ppm, from about 200 ppm to about 375 ppm, from about 200 ppm to about 400 ppm, from about 250 ppm to about 275 ppm, from about 250 ppm to about 300 ppm, from about 250 ppm to about 325 ppm, from about 250 ppm to about 350 ppm, from about 250 ppm to about 375 ppm, from about 250 ppm to about 400 ppm , from about 300 ppm to about 325 ppm, from about 300 ppm to about 350 ppm, from about 300 ppm to about 375 ppm, from about 300 ppm to about 400 ppm, from about 350 ppm to about 375 ppm, from about 350 ppm to about 400 ppm or from about 375 ppm to about 400 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount, for example, from about 400 ppm to about 500 ppm, from about 400 ppm to about 600 ppm, from about 400 ppm to about 700 ppm, from from about 400 ppm to about 800 ppm, from about 400 ppm to about 900 ppm, from about 400 ppm to about 1000 ppm, from about 400 ppm to about 1100 ppm, from about 400 ppm to about 1200 ppm, from about 400 ppm to about 1300 ppm, from about 400 ppm to about 1400 ppm, from about 400 ppm to about 1500 ppm, from about 400 ppm to about 1600 ppm, from about 400 ppm to about 1700 ppm, from about 400 ppm to about 1800 ppm, from about 400 ppm to about 1900 ppm, from about 400 ppm to about 2000 ppm, from about 500 ppm to about 600 ppm, from about 500 ppm to about 700 ppm, from about 500 ppm to about 800 ppm, from about 500 ppm to about 900 ppm, from about 500 ppm to about 1000 ppm, from about 500 ppm to about 1100 ppm, from about 500 ppm to about 1200 ppm, from about 500 ppm to about 1300 ppm, from about 500 ppm to about 1400 ppm, from about 500 ppm to about 1500 ppm, from about 500 ppm to about 1600 ppm, from about 500 ppm to about 1700 ppm, from about 500 ppm to about 1800 ppm, from about 500 ppm to about 1900 ppm, from about 500 ppm to about 2000 ppm , from about 600 ppm to about 700 ppm, from about 600 ppm to about 800 ppm, from about 600 ppm to about 900 ppm, from about 600 ppm to about 1000 ppm, from about 600 ppm to about 1100 ppm, from about 600 ppm to about 1200 ppm, from about 600 ppm to about 1300 ppm, from about 600 ppm to about 1400 ppm, from about 600 ppm to about 1500 ppm, from about 600 ppm to about 1600 ppm, from about 600 ppm to about 1700 ppm, from about 600 ppm to about 1800 ppm, from about 600 ppm to about 1900 ppm, from about 600 ppm to about 2000 ppm, from about 700 ppm to about 800 ppm, from about 700 ppm to about 900 ppm, from about 700 ppm to about 1000 ppm, from about 700 ppm to about 1100 ppm, from about 700 ppm to about 1200 ppm, from about 700 ppm to about 1300 ppm, from about 700 ppm to about 1400 ppm, from about 700 ppm to about 1500 ppm, from from about 700 ppm to about 1600 ppm, from about 700 ppm to about 1700 ppm, from about 700 ppm to about 1800 ppm, from about 700 ppm to about 1900 ppm, from about 700 ppm to about 2000 ppm, from about 800 ppm to about 900 ppm, from about 800 ppm to about 1000 ppm, from about 800 ppm to about 1100 ppm, from about 800 ppm to about 1200 ppm, from about 800 ppm to about 1300 ppm, from about 800 ppm to about 1400 ppm, from about 800 ppm to about 1500 ppm, from about 800 ppm to about 1600 ppm, from about 800 ppm to about 1700 ppm, from about 800 ppm to about 1800 ppm, from about 800 ppm to about 1900 ppm, from about 800 ppm to about 2000 ppm, from about 900 ppm to about 1000 ppm, from about 900 ppm to about 1100 ppm, from about 900 ppm to about 1200 ppm, from about 900 ppm to about 1300 ppm, from about 900 ppm to about 1400 ppm, from about 900 ppm to about 1500 ppm, from about 900 ppm to about 1600 ppm, from about 900 ppm to about 1700 ppm, from about 900 ppm to about 1800 ppm, from about 900 ppm to about 1900 ppm, from about 900 ppm to about 2000 ppm , from about 1000 ppm to about 1100 ppm, from about 1000 ppm to about 1200 ppm, from about 1000 ppm to about 1300 ppm, from about 1000 ppm to about 1400 ppm, from about 1000 ppm to about 1500 ppm, from about 1000 ppm to about 1600 ppm, from about 1000 ppm to about 1700 ppm, from about 1000 ppm to about 1800 ppm, from about 1000 ppm to about 1900 ppm, from about 1000 ppm to about 2000 ppm, from about 1100 ppm to about 1200 ppm, from about 1100 ppm to about 1300 ppm, from about 1100 ppm to about 1400 ppm, from about 1100 ppm to about 1500 ppm, from about 1100 ppm to about 1600 ppm, from about 1100 ppm to about 1700 ppm, from about 1100 ppm to from about 1800 ppm, from about 1100 ppm to about 1900 ppm, from about 1100 ppm to about 2000 ppm, from about 1200 ppm to about 1300 ppm, from about 1200 ppm to about 1400 ppm, from about 1200 ppm to about 1500 ppm, from about 1200 ppm to about 1600 ppm, from about 1200 ppm to about 1700 ppm, from about 1200 ppm to example

- 25 043933 but 1800 ppm, from about 1200 ppm to about 1900 ppm, from about 1200 ppm to about 2000 ppm, from about 1300 ppm to about 1400 ppm, from about 1300 ppm to about 1500 ppm, from about 1300 ppm to about 1600 ppm, from about 1300 ppm to about 1700 ppm, from about 1300 ppm to about 1800 ppm, from about 1300 ppm to about 1900 ppm, from about 1300 ppm to about 2000 ppm, from about 1400 ppm to about 1500 ppm, from about 1400 ppm to about 1600 ppm, from about 1400 ppm to about 1700 ppm, from about 1400 ppm to about 1800 ppm, from about 1400 ppm to about 1900 ppm, from about 1400 ppm to about 2000 ppm, from about 1500 ppm to about 1600 ppm , from about 1500 ppm to about 1700 ppm, from about 1500 ppm to about 1800 ppm, from about 1500 ppm to about 1900 ppm, from about 1500 ppm to about 2000 ppm, from about 1600 ppm to about 1700 ppm, from about 1600 ppm to about 1800 ppm, from about 1600 ppm to about 1900 ppm, from about 1600 ppm to about 2000 ppm, from about 1700 ppm to about 1800 ppm, from about 1700 ppm to about 1900 ppm, from about 1700 ppm to about 2000 ppm, from about 1800 ppm to about 1900 ppm, from about 1800 ppm to about 2000 ppm, or from about 1900 ppm to about 2000 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, 0.05 mg/L, 0.10 mg/L, 0.15 mg/L, 0.20 mg/L, 0.25 mg/l, 0.30 mg/l, 0.35 mg/l, 0.40 mg/l, 0.45 mg/l, 0.50 mg/l, 0.55 mg/l, 0 .60 mg/l, 0.65 mg/l,

0.70 mg/l, 0.75 mg/l, 0.80 mg/l, 0.85 mg/l, 0.90 mg/l, 0.95 mg/l, 1 mg/l, 5 mg/ l, 10 mg/l, 15 mg/l, 20 mg/l, mg/l, 30 mg/l, 35 mg/l, 40 mg/l, 45 mg/l, 50 mg/l, 55 mg/l , 60 mg/l, 65 mg/l, 70 mg/l, 75 mg/l, 80 mg/l, mg/l, 90 mg/l, 95 mg/l, 100 mg/l, 125 mg/l, 150 mg/l, 175 mg/l, 200 mg/l, 225 mg/l, 250 mg/l, 275 mg/l,

300 mg/l, 325 mg/l, 350 mg/l, 375 mg/l, 400 mg/l, 425 mg/l, 450 mg/l, 475 mg/l, 500 mg/l, 525 mg/l, 550 mg/l, 575 mg/l, 600 mg/l, 625 mg/l, 650 mg/l, 675 mg/l, 700 mg/l, 725 mg/l, 750 mg/l, 775 mg/l, 800 mg/l, 825 mg/l, 850 mg/l, 875 mg/l, 900 mg/l, 925 mg/l, 950 mg/l, 975 mg/l, 1000 mg/l, 1025 mg/l, 1050 mg/l, 1075 mg/l, 1100 mg/l, 1125 mg/l, 1150 mg/l, 1175 mg/l, 1200 mg/l, 1225 mg/l, 1250 mg/l, 1275 mg/l, 1300 mg/l, 1325 mg/l, 1350 mg/l, 1375 mg/l, 1400 mg/l, 1425 mg/l, 1450 mg/l, 1475 mg/l, 1500 mg/l, 1600 mg/l, 1700 mg/l, 1800 mg/l, 1900 mg/l or 2000 mg/l. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, at least 0.05 mg/L, at least 0.10 mg/L, at least 0.20 mg/L l, at least 0.30 mg/l, at least 0.40 mg/l, at least 0.50 mg/l, at least 0.60 mg/l, at least 0.70 mg/l l, at least 0.80 mg/l, at least 0.90 mg/l, at least 1 mg/l, at least 10 mg/l, at least 20 mg/l, at least 30 mg/l, at least 40 mg/l, at least 50 mg/l, at least 60 mg/l, at least 70 mg/l, at least 80 mg/l, at least 90 mg/ l, at least 100 mg/l, at least 125 mg/l, at least 150 mg/l, at least 175 mg/l, at least 200 mg/l, at least 225 mg/l, at least 250 mg/l, at least 275 mg/l, at least 300 mg/l, at least 325 mg/l, at least 350 mg/l, at least 375 mg/l, at least at least 400 mg/l, at least 425 mg/l, at least 450 mg/l, at least 475 mg/l, at least 500 mg/l, at least 525 mg/l, at least 550 mg/l, at least 575 mg/l, at least 600 mg/l, at least 625 mg/l, at least 650 mg/l, at least 675 mg/l, at least 700 mg/l l, at least 725 mg/l, at least 750 mg/l, at least 775 mg/l, at least 800 mg/l, at least 825 mg/l, at least 850 mg/l, at least 875 mg/l, at least 900 mg/l, at least 925 mg/l, at least 950 mg/l, at least 975 mg/l, at least 1000 mg/l, at least at least 1025 mg/l, at least 1050 mg/l, at least 1075 mg/l, at least 1100 mg/l, at least 1125 mg/l, at least 1150 mg/l, at least 1175 mg/l, at least 1200 mg/l, at least 1225 mg/l, at least 1250 mg/l, at least 1275 mg/l, at least 1300 mg/l, at least 1325 mg/l l, at least 1350 mg/l, at least 1375 mg/l, at least 1400 mg/l, at least 1425 mg/l, at least 1450 mg/l, at least 1475 mg/l, at least 1500 mg/L, at least 1600 mg/L, at least 1700 mg/L, at least 1800 mg/L, at least 1900 mg/L or at least 2000 mg/L. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, no more than 0.05 mg/L, no more than 0.10 mg/L, no more than 0.20 mg/L, no more than 0.30 mg/l, no more than 0.40 mg/l, no more than 0.50 mg/l, no more than 0.60 mg/l, no more than 0.70 mg/l, no more than 0.80 mg /l, not more than 0.90 mg/l, not more than 1 mg/l, not more than 10 mg/l, not more than 20 mg/l, not more than 30 mg/l, not more than 40 mg/l, not more than 50 mg/l, not more than 60 mg/l, not more than 70 mg/l, not more than 80 mg/l, not more than 90 mg/l, not more than 100 mg/l, not more than 125 mg/l, not more than 150 mg /l, no more than 175 mg/l, no more than 200 mg/l, no more than 225 mg/l, no more than 250 mg/l, no more than 275 mg/l, no more than 300 mg/l, no more than 325 mg/ l, no more than 350 mg/l, no more than 375 mg/l, no more than 400 mg/l, no more than 425 mg/l, no more than 450 mg/l, no more than 475 mg/l, no more than 500 mg/l , no more than 525 mg/l, no more than 550 mg/l, no more than 575 mg/l, no more than 600 mg/l, no more than 625 mg/l, no more than 650 mg/l, no more than 675 mg/l, not more than 700 mg/l, not more than 725 mg/l, not more than 750 mg/l, not more than 775 mg/l, not more than 800 mg/l, not more than 825 mg/l, not more than 850 mg/l, not more than 875 mg/l, no more than 900 mg/l, no more than 925 mg/l, no more than 950 mg/l, no more than 975 mg/l, no more than 1000 mg/l, no more than 1025 mg/l, no more 1050 mg/l, not more than 1075 mg/l, not more than 1100 mg/l, not more than 1125 mg/l, not more

- 26 043933

1150 mg/l, not more than 1175 mg/l, not more than 1200 mg/l, not more than 1225 mg/l, not more than 1250 mg/l, not more

1275 mg/l, not more than 1300 mg/l, not more than 1325 mg/l, not more than 1350 mg/l, not more than 1375 mg/l, not more

1400 mg/l, no more than 1425 mg/l, no more than 1450 mg/l, no more than 1475 mg/l, no more than 1500 mg/l, no more

1600 mg/l, not more than 1700 mg/l, not more than 1800 mg/l, not more than 1900 mg/l or not more than 2000 mg/l.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, from about 0.5 mg/L to about 20 mg/L, from about 0.5 mg/L to about 25 mg/L l, from about 0.5 mg/L to about 30 mg/L, from about 0.5 mg/L to about 35 mg/L, from about 0.5 mg/L to about 40 mg/L, from about 0 .5 mg/L to about 45 mg/L, from about 0.5 mg/L to about 50 mg/L, from about 0.5 mg/L to about 55 mg/L, from about 0.5 mg/L to about 60 mg/L, from about 0.5 mg/L to about 65 mg/L, from about 0.5 mg/L to about 70 mg/L, from about 0.5 mg/L to about 75 mg/L l, from about 0.5 mg/L to about 80 mg/L, from about 0.5 mg/L to about 85 mg/L, from about 0.5 mg/L to about 90 mg/L, from about 0 .5 mg/L to about 95 mg/L, from about 0.5 mg/L to about 100 mg/L, from about 0.75 mg/L to about 20 mg/L, from about 0.75 mg/L to about 25 mg/L, from about 0.75 mg/L to about 30 mg/L, from about 0.75 mg/L to about 35 mg/L, from about 0.75 mg/L to about 40 mg/L l, from about 0.75 mg/L to about 45 mg/L, from about 0.75 mg/L to about 50 mg/L, from about 0.75 mg/L to about 55 mg/L, from about 0 .75 mg/L to about 60 mg/L, from about 0.75 mg/L to about 65 mg/L, from about 0.75 mg/L to about 70 mg/L, from about 0.75 mg/L to about 75 mg/L, from about 0.75 mg/L to about 80 mg/L, from about 0.75 mg/L to about 85 mg/L, from about 0.75 mg/L to about 90 mg/L l, from about 0.75 mg/L to about 95 mg/L, from about 0.75 mg/L to about 100 mg/L, from about 1 mg/L to about 20 mg/L, from about 1 mg/L l to about 25 mg/L, from about 1 mg/L to about 30 mg/L, from about 1 mg/L to about 35 mg/L, from about 1 mg/L to about 40 mg/L, from about 1 mg/L to about 45 mg/L, from about 1 mg/L to about 50 mg/L, from about 1 mg/L to about 55 mg/L, from about 1 mg/L to about 60 mg/L, from about 1 mg/L to about 65 mg/L, about 1 mg/L to about 70 mg/L, about 1 mg/L to about 75 mg/L, about 1 mg/L to about 80 mg/L , from about 1 mg/L to about 85 mg/L, from about 1 mg/L to about 90 mg/L, from about 1 mg/L to about 95 mg/L, from about 1 mg/L to about 100 mg /L, from about 5 mg/L to about 20 mg/L, from about 5 mg/L to about 25 mg/L, from about 5 mg/L to about 30 mg/L, from about 5 mg/L to about 35 mg/L, from about 5 mg/L to about 40 mg/L, from about 5 mg/L to about 45 mg/L, from about 5 mg/L to about 50 mg/L, from about 5 mg/L to about 55 mg/L, from about 5 mg/L to about 60 mg/L, from about 5 mg/L to about 65 mg/L, from about 5 mg/L to about 70 mg/L, from about 5 mg /L to about 75 mg/L, from about 5 mg/L to about 80 mg/L, from about 5 mg/L to about 85 mg/L, from about 5 mg/L to about 90 mg/L, from about 5 mg/L to about 95 mg/L, about 5 mg/L to about 100 mg/L, about 10 mg/L to about 20 mg/L, about 10 mg/L to about 25 mg/L, from about 10 mg/L to about 30 mg/L, from about 10 mg/L to about 35 mg/L, from about 10 mg/L to about 40 mg/L, from about 10 mg/L to about 45 mg/ l, from about 10 mg/L to about 50 mg/L, from about 10 mg/L to about 55 mg/L, from about 10 mg/L to about 60 mg/L, from about 10 mg/L to about 65 mg/L, from about 10 mg/L to about 70 mg/L, from about 10 mg/L to about 75 mg/L, from about 10 mg/L to about 80 mg/L, from about 10 mg/L to about 85 mg/L, about 10 mg/L to about 90 mg/L, about 10 mg/L to about 95 mg/L, or about 10 mg/L to about 100 mg/L.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount, for example, from about 1 mg/L to about 25 mg/L, from about 1 mg/L to about 50 mg/L, from about 1 mg/L to about 75 mg/L, about 1 mg/L to about 100 mg/L, about 1 mg/L to about 125 mg/L, about 1 mg/L to about 150 mg/L, from about 1 mg/L to about 175 mg/L, from about 1 mg/L to about 200 mg/L, from about 1 mg/L to about 225 mg/L, from about 1 mg/L to about 250 mg/L l, from about 1 mg/L to about 275 mg/L, from about 1 mg/L to about 300 mg/L, from about 1 mg/L to about 325 mg/L, from about 1 mg/L to about 350 mg/L, from about 1 mg/L to about 375 mg/L, from about 1 mg/L to about 400 mg/L, from about 10 mg/L to about 25 mg/L, from about 10 mg/L to about 50 mg/L, about 10 mg/L to about 75 mg/L, about 10 mg/L to about 100 mg/L, about 10 mg/L to about 125 mg/L, about 10 mg/L l to about 150 mg/L, from about 10 mg/L to about 175 mg/L, from about 10 mg/L to about 200 mg/L, from about 10 mg/L to about 225 mg/L, from about 10 mg/L to about 250 mg/L, from about 10 mg/L to about 275 mg/L, from about 10 mg/L to about 300 mg/L, from about 10 mg/L to about 325 mg/L, from about 10 mg/L to about 350 mg/L, about 10 mg/L to about 375 mg/L, about 10 mg/L to about 400 mg/L, about 25 mg/L to about 50 mg/L , from about 25 mg/L to about 75 mg/L, from about 25 mg/L to about 100 mg/L, from about 25 mg/L to about 125 mg/L, from about 25 mg/L to about 150 mg /L, from about 25 mg/L to about 175 mg/L, from about 25 mg/L to about 200 mg/L, from about 25 mg/L to about 225 mg/L, from about 25 mg/L to about 250 mg/L, from about 25 mg/L to about 275 mg/L, from about 25 mg/L to about 300 mg/L, from about 25 mg/L to about 325 mg/L, from about 25 mg/L to about 350 mg/l, from about 25 mg/l to about 375 mg/l, from about 25 mg/l to about 400 mg/l, from about 50 mg/l to about 75 mg/l, from about 50 mg/L to about 100 mg/L, from about 50 mg/L to about 125 mg/L, from about 50 mg/L to about 150 mg/L, from about 50 mg/L to about 175 mg/L l, from about 50 mg/L to about 200 mg/L, from about 50 mg/L to about 225 mg/L, from about 50 mg/L to about 250 mg/L, from about 50 mg/L to about 275 mg/L, from about 50 mg/L to about 300 mg/L, from about 50 mg/L to about 325 mg/L, from about 50 mg/L to about 350 mg/L, from about 50 mg/L to about 375 mg/L, about 50 mg/L to about 400 mg/L, about 75 mg/L to about 100 mg/L, about 75 mg/L to about 125 mg/L, about 75 mg/L l to about 150 mg/L, from about 75 mg/L to about 175 mg/L, from about 75 mg/L to about 200 mg/L, from about 75 mg/L to about 225 mg/L, from about 75 mg/L to about 250 mg/L, from about 75 mg/L to about 275 mg/L, from about 75 mg/L to about 300 mg/L, from about 75 mg/L to about 325 mg/L, from about 75 mg/L to about 350 mg/L, about 75 mg/L to about 375 mg/L, about 75 mg/L to about 400 mg/L, about 100 mg/L to about 125 mg/L , from about 100 mg/L to about 150 mg/L, from about 100 mg/L to about 175 mg/L, from about 100 mg/L to about 200 mg/L, from about 100 mg/L to about 225 mg /L, from about 100 mg/L to about 250 mg/L, from about 100 mg/L to about 275 mg/L, from about 100 mg/L to about 300 mg/L, from about 100 mg/L to about 325 mg/L, from about 100 mg/L to about 350 mg/L, from about 100 mg/L to about 375 mg/L, from about 100 mg/L to about 400 mg/L, from about 150 mg/L to about 175 mg/L, from about 150 mg/L to about 200 mg/L, from about 150 mg/L to about 225 mg/L, from about 150 mg/L to about 250 mg/L, from about 150 mg /L to about 275 mg/L, from about 150 mg/L to about 300 mg/L, from about 150 mg/L to about 325 mg/L, from about 150 mg/L to about 350 mg/L, from about 150 mg/L to about 375 mg/L, from about 150 mg/L to about 400 mg/L, from about 200 mg/L to about 225 mg/L, from about 200 mg/L to about 250 mg/L, from about 200 mg/L to about 275 mg/L, from about 200 mg/L to about 300 mg/L, from about 200 mg/L to about 325 mg/L, from about 200 mg/L to about 350 mg/L l, from about 200 mg/L to about 375 mg/L, from about 200 mg/L to about 400 mg/L, from about 250 mg/L to about 275 mg/L, from about 250 mg/L to about 300 mg/L, from about 250 mg/L to about 325 mg/L, from about 250 mg/L to about 350 mg/L, from about 250 mg/L to about 375 mg/L, from about 250 mg/L to about 400 mg/L, from about 300 mg/L to about 325 mg/L, from about 300 mg/L to about 350 mg/L, from about 300 mg/L to about 375 mg/L, from about 300 mg/L l to about 400 mg/L, from about 350 mg/L to about 375 mg/L, from about 350 mg/L to about 400 mg/L, or from about 375 mg/L to about 400 mg/L.

In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount, for example, from about 400 mg/L to about 500 mg/L, from about 400 mg/L to about 600 mg/L, from about 400 mg/L to about 700 mg/L, from about 400 mg/L to about 800 mg/L, from about 400 mg/L to about 900 mg/L, from about 400 mg/L to about 1000 mg/L, from about 400 mg/L to about 1100 mg/L, from about 400 mg/L to about 1200 mg/L, from about 400 mg/L to about 1300 mg/L, from about 400 mg/L to about 1400 mg/L l, from about 400 mg/L to about 1500 mg/L, from about 400 mg/L to about 1600 mg/L, from about 400 mg/L to about 1700 mg/L, from about 400 mg/L to about 1800 mg/L, from about 400 mg/L to about 1900 mg/L, from about 400 mg/L to about 2000 mg/L, from about 500 mg/L to about 600 mg/L, from about 500 mg/L to about 700 mg/L, from about 500 mg/L to about 800 mg/L, from about 500 mg/L to about 900 mg/L, from about 500 mg/L to about 1000 mg/L, from about 500 mg/L l to about 1100 mg/l, from about 500 mg/l to about 1200 mg/l, from about 500 mg/l to about 1300 mg/l, from about 500 mg/l to about 1400 mg/l, from about 500 mg/L to about 1500 mg/L, from about 500 mg/L to about 1600 mg/L, from about 500 mg/L to about 1700 mg/L, from about 500 mg/L to about 1800 mg/L, from about 500 mg/L to about 1900 mg/L, about 500 mg/L to about 2000 mg/L, about 600 mg/L to about 700 mg/L, about 600 mg/L to about 800 mg/L , from about 600 mg/L to about 900 mg/L, from about 600 mg/L to about 1000 mg/L, from about 600 mg/L to about 1100 mg/L, from about 600 mg/L to about 1200 mg /L, from about 600 mg/L to about 1300 mg/L, from about 600 mg/L to about 1400 mg/L, from about 600 mg/L to about 1500 mg/L, from about 600 mg/L to about 1600 mg/L, from about 600 mg/L to about 1700 mg/L, from about 600 mg/L to about 1800 mg/L, from about 600 mg/L to about 1900 mg/L, from about 600 mg/L to about 2000 mg/L, from about 700 mg/L to about 800 mg/L, from about 700 mg/L to about 900 mg/L, from about 700 mg/L to about 1000 mg/L, from about 700 mg /L to about 1100 mg/L, from about 700 mg/L to about 1200 mg/L, from about 700 mg/L to about 1300 mg/L, from about 700 mg/L to about 1400 mg/L, from about 700 mg/L to about 1500 mg/L, from about 700 mg/L to about 1600 mg/L, from about 700 mg/L to about 1700 mg/L, from about 700 mg/L to about 1800 mg/L, from about 700 mg/L to about 1900 mg/L, from about 700 mg/L to about 2000 mg/L, from about 800 mg/L to about 900 mg/L, from about 800 mg/L to about 1000 mg/L l, from about 800 mg/L to about 1100 mg/L, from about 800 mg/L to about 1200 mg/L, from about 800 mg/L to about 1300 mg/L, from about 800 mg/L to about 1400 mg/L, from about 800 mg/L to about 1500 mg/L, from about 800 mg/L to about 1600 mg/L, from

- 28 043933 about 800 mg/l to about 1700 mg/l, from about 800 mg/l to about 1800 mg/l, from about 800 mg/l to about 1900 mg/l, from about 800 mg/l to about 2000 mg/L, from about 900 mg/L to about 1000 mg/L, from about 900 mg/L to about 1100 mg/L, from about 900 mg/L to about 1200 mg/L, from about 900 mg/L to about 1300 mg/L, from about 900 mg/L to about 1400 mg/L, from about 900 mg/L to about 1500 mg/L, from about 900 mg/L to about 1600 mg/L, from about 900 mg/L L to about 1700 mg/L, from about 900 mg/L to about 1800 mg/L, from about 900 mg/L to about 1900 mg/L, from about 900 mg/L to about 2000 mg/L, from about 1000 mg/L to about 1100 mg/L, from about 1000 mg/L to about 1200 mg/L, from about 1000 mg/L to about 1300 mg/L, from about 1000 mg/L to about 1400 mg/L, from about 1000 mg/L to about 1500 mg/L, about 1000 mg/L to about 1600 mg/L, about 1000 mg/L to about 1700 mg/L, about 1000 mg/L to about 1800 mg/L , from about 1000 mg/L to about 1900 mg/L, from about 1000 mg/L to about 2000 mg/L, from about 1100 mg/L to about 1200 mg/L, from about 1100 mg/L to about 1300 mg /L, from about 1100 mg/L to about 1400 mg/L, from about 1100 mg/L to about 1500 mg/L, from about 1100 mg/L to about 1600 mg/L, from about 1100 mg/L to about 1700 mg/L, from about 1100 mg/L to about 1800 mg/L, from about 1100 mg/L to about 1900 mg/L, from about 1100 mg/L to about 2000 mg/L, from about 1200 mg/L to about 1300 mg/L, from about 1200 mg/L to about 1400 mg/L, from about 1200 mg/L to about 1500 mg/L, from about 1200 mg/L to about 1600 mg/L, from about 1200 mg /L to about 1700 mg/L, from about 1200 mg/L to about 1800 mg/L, from about 1200 mg/L to about 1900 mg/L, from about 1200 mg/L to about 2000 mg/L, from about 1300 mg/L to about 1400 mg/L, from about 1300 mg/L to about 1500 mg/L, from about 1300 mg/L to about 1600 mg/L, from about 1300 mg/L to about 1700 mg/L, from about 1300 mg/L to about 1800 mg/L, from about 1300 mg/L to about 1900 mg/L, from about 1300 mg/L to about 2000 mg/L, from about 1400 mg/L to about 1500 mg/L l, from about 1400 mg/L to about 1600 mg/L, from about 1400 mg/L to about 1700 mg/L, from about 1400 mg/L to about 1800 mg/L, from about 1400 mg/L to about 1900 mg/L, from about 1400 mg/L to about 2000 mg/L, from about 1500 mg/L to about 1600 mg/L, from about 1500 mg/L to about 1700 mg/L, from about 1500 mg/L to about 1800 mg/L, about 1500 mg/L to about 1900 mg/L, about 1500 mg/L to about 2000 mg/L, about 1600 mg/L to about 1700 mg/L, about 1600 mg/L L to about 1800 mg/L, from about 1600 mg/L to about 1900 mg/L, from about 1600 mg/L to about 2000 mg/L, from about 1700 mg/L to about 1800 mg/L, from about 1700 mg/L to about 1900 mg/L, from about 1700 mg/L to about 2000 mg/L, from about 1800 mg/L to about 1900 mg/L, from about 1800 mg/L to about 2000 mg/L, or from about 1900 mg/L to about 2000 mg/L.

In aspects according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, about 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14% , approximately 0.15%, approximately 0.16%, approximately 0.17%, approximately 0.18%, approximately 0.19%, approximately 0.2%, approximately 0.25%, approximately 0.3%, approximately 0.35%, about 0.4%, about 0.45%, or about 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, at least 0.10%, at least 0.11%, at least 0.12%, at least 0 .13%, at least 0.14%, at least 0.15%, at least 0.16%, at least 0.17%, at least 0.18%, at least 0.19 %, at least 0.2%, at least 0.25%, at least 0.3%, at least 0.35%, at least 0.4%, at least 0.45% or at least 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, no more than 0.10%, no more than 0.11%, no more than 0.12%, no more than 0.13%, not more than 0.14%, not more than 0.15%, not more than 0.16%, not more than 0.17%, not more than 0.18%, not more than 0.19%, not more than 0.2%, not more than 0.25%, no more than 0.3%, no more than 0.35%, no more than 0.4%, no more than 0.45% or no more than 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains metal particles in an amount of, for example, from about 0.10% to about 0.15%, from about 0.10% to about 0.20%, from about 0.10% to about 0.25%, from about 0.10% to about 0.30%, from about 0.10% to about 0.35%, from about 0.10% to about 0.40%, from about 0.10% to about 0.45%, from about 0.10% to about

0.50%, from about 0.20% to about 0.25%, from about 0.20% to about 0.30%, from about

0.20% to about 0.35%, from about 0.20% to about 0.40%, from about 0.20% to about

0.45%, from about 0.20% to about 0.50%, from about 0.30% to about 0.35%, from about

0.30% to about 0.40%, from about 0.30% to about 0.45%, from about 0.30% to about

0.50%, from about 0.40% to about 0.45%, or from about 0.40% to about 0.50% by weight of the composition.

In one embodiment, the metal particles can be of any size that imparts the desired beneficial effect to the composition described herein. In aspects according to this embodiment, the metal particles described in the present invention have an average diameter of, for example, about 10 nm, about 20 nm, about 30 nm, about 40 nm, with

- 29 043933 approximately 50 nm, approximately 60 nm, approximately 70 nm, approximately 80 nm, approximately 90 nm, approximately 100 nm. In other aspects, according to this embodiment, the metal particles described in the present invention have an average diameter, for example, at least 10 nm, at least 20 nm, at least 30 nm, at least 40 nm, at least 50 nm , at least 60 nm, at least 70 nm, at least 80 nm, at least 90 nm, at least 100 nm. In other aspects, according to this embodiment, the metal particles described in the present invention have an average diameter of, for example, no more than 10 nm, no more than 20 nm, no more than 30 nm, no more than 40 nm, no more than 50 nm, no more than 60 nm , no more than 70 nm, no more than 80 nm, no more than 90 nm, no more than 100 nm. In other aspects, according to this embodiment, the metal particles described in the present invention have an average diameter, for example, from about 10 nm to about 20 nm, from about 10 nm to about 30 nm, from about 10 nm to about 40 nm, from about 10 nm to about 50 nm, from about 10 nm to about 60 nm, from about 10 nm to about 70 nm, from about 10 nm to about 80 nm, from about 10 nm to about 90 nm, from about 10 nm to about 100 nm, from about 20 nm to about 30 nm, from about 20 nm to about 40 nm, from about 20 nm to about 50 nm, from about 20 nm to about 60 nm, from about 20 nm to about 70 nm, from about 20 nm to about 80 nm, from about 20 nm to about 90 nm, from about 20 nm to about 100 nm, from about 30 nm to about 40 nm, from about 30 nm to about 50 nm, from about 30 nm to about 60 nm , from about 30 nm to about 70 nm, from about 30 nm to about 80 nm, from about 30 nm to about 90 nm, from about 30 nm to about 100 nm, from about 40 nm to about 50 nm, from about 40 nm to about 60 nm, from about 40 nm to about 70 nm, from about 40 nm to about 80 nm, from about 40 nm to about 90 nm, from about 40 nm to about 100 nm, from about 50 nm to about 60 nm, from about 50 nm to about 70 nm, from about 50 nm to about 80 nm, from about 50 nm to about 90 nm, from about 50 nm to about 100 nm, from about 60 nm to about 70 nm, from about 60 nm to about 80 nm, from about 60 nm to about 90 nm, from about 60 nm to about 100 nm, from about 70 nm to about 80 nm, from about 70 nm to about 90 nm, from about 70 nm to about 100 nm, from about 80 nm to about 90 nm, about 80 nm to about 100 nm, or about 90 nm to about 100 nm.

In one embodiment, the composition described in the present invention does not contain metal particles.

The composition described in the present invention may contain a metal salt. Non-limiting examples of metal salts include copper salt, iron salt, potassium salt, silver salt, titanium salt and zinc salt. Other non-limiting examples of metal salts include metal acetate, metal chloride, metal nitrate and metal sulfate. Metal acetates include, but are not limited to, copper acetate, iron acetate, such as iron(II) acetate and iron(III) acetate, potassium acetate, silver acetate, titanium acetate and zinc acetate. Metal chlorides include, but are not limited to, copper chloride, ferric chloride, such as ferric (II) chloride or ferric (III) chloride, potassium chloride, silver chloride, titanium chloride and zinc chloride. Metal nitrates include, but are not limited to, copper nitrate, iron nitrate, such as iron(II) nitrate, iron(III) nitrate, potassium nitrate, silver nitrate, titanium nitrate and zinc nitrate. Metal sulfates include, but are not limited to, copper sulfate, ferrous sulfate, for example, iron (II) sulfate, iron (III) sulfate, potassium sulfate, silver sulfate, titanium sulfate and zinc sulfate.

In one embodiment, the composition described in the present invention contains a metal salt in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, 0.05 ppm, 0.10 ppm, 0.15 ppm, 0.20 ppm, 0.25 ppm, 0.30 ppm , 0.35 ppm, 0.40 ppm, 0.45 ppm, 0.50 ppm, 0.55 ppm, 0.60 ppm, 0.65 ppm, 0.70 ppm, 0.75 ppm, 0.80 ppm , 0.85 ppm, 0.90 ppm, 0.95 ppm, 1 ppm, 5 ppm, 10 ppm, 15 ppm, 20 ppm, 25 ppm, 30 ppm, 35 ppm, 40 ppm, 45 ppm, 50 ppm, 55 ppm, 60 ppm, 65 ppm, 70 ppm, 75 ppm, 80 ppm, 85 ppm, 90 ppm, 95 ppm, 100 ppm, 125 ppm, 150 ppm, 175 ppm, 200 ppm, 225 ppm, 250 ppm, 275 ppm, 300 ppm, 325 ppm, 350 ppm, 375 ppm, 400 ppm, 425 ppm, 450 ppm, 475 ppm, 500 ppm, 525 ppm, 550 ppm, 575 ppm, 600 ppm, 625 ppm, 650 ppm, 675 ppm, 700 ppm , 725 ppm, 750 ppm, 775 ppm, 800 ppm, 825 ppm, 850 ppm, 875 ppm, 900 ppm, 925 ppm, 950 ppm, 975 ppm, 1000 ppm, 1025 ppm, 1050 ppm, 1075 ppm, 1100 ppm, 11 25 ppm, 1150 ppm, 1175 ppm, 1200 ppm, 1225 ppm, 1250 ppm, 1275 ppm, 1300 ppm, 1325 ppm, 1350 ppm, 1375 ppm, 1400 ppm, 1425 ppm, 1450 ppm, 1475 ppm, 1500 ppm , 1600 ppm, 1700 ppm, 1800 ppm, 1900 ppm or 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, at least 0.05 ppm, at least 0.10 ppm, at least 0.20 ppm, at least 0 .30 ppm, at least 0.40 ppm, at least 0.50 ppm, at least 0.60 ppm, at least 0.70 ppm, at least

0.80 ppm, at least 0.90 ppm, at least 1 ppm, at least 10 ppm, at least 20 ppm, at least 30 ppm, at least 40 ppm, at least 50 ppm, according to at least 60 ppm, at least 70 ppm, at least 80 ppm, at least 90 ppm, at least 100 ppm, at least 125 ppm, at least 150 ppm, at least 175 ppm, at least

- 30 043933 at least 200 ppm, at least 225 ppm, at least 250 ppm, at least 275 ppm, at least 300 ppm, at least 325 ppm, at least 350 ppm, at least 375 ppm, according to at least 400 ppm, at least 425 ppm, at least 450 ppm, at least 475 ppm, at least 500 ppm, at least 525 ppm, at least 550 ppm, at least 575 ppm, at least 600 ppm, at least 625 ppm, at least 650 ppm, at least 675 ppm, at least 700 ppm, at least 725 ppm, at least 750 ppm, at least 775 ppm, at least 800 ppm , at least 825 ppm, at least 850 ppm, at least 875 ppm, at least 900 ppm, at least 925 ppm, at least 950 ppm, at least 975 ppm, at least 1000 ppm, according to at least 1025 ppm, at least 1050 ppm, at least 1075 ppm, at least 1100 ppm, at least 1125 ppm, at least 1150 ppm, at least 1175 ppm, at least 1200 ppm, at least 1225 ppm, at least 1250 ppm, at least 1275 ppm, at least 1300 ppm, at least 1325 ppm, at least 1350 ppm, at least 1375 ppm, at least 1400 ppm, at least 1425 ppm , at least 1450 ppm, at least 1475 ppm, at least 1500 ppm, at least 1600 ppm, at least 1700 ppm, at least 1800 ppm, at least 1900 ppm or at least 2000 ppm. In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, no more than 0.05 ppm, no more than 0.10 ppm, no more than 0.20 ppm, no more than 0.30 ppm, no more than 0.40 ppm, no more than 0.50 ppm, no more than 0.60 ppm, no more than 0.70 ppm, no more than 0.80 ppm, no more than 0.90 ppm, no more than 1 ppm, no more than 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm, no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm, no more than 125 ppm, no more than 150 ppm, no more than 175 ppm, no more than 200 ppm, no more than 225 ppm, no more than 250 ppm, no more than 275 ppm, no more than 300 ppm, no more than 325 ppm, no more than 350 ppm, no more than 375 ppm, no more than 400 ppm, no more than 425 ppm, no more than 450 ppm, no more than 475 ppm, no more than 500 ppm, no more than 525 ppm, no more than 550 ppm, no more than 575 ppm, no more than 600 ppm, no more than 625 ppm, no more than 650 ppm, no more than 675 ppm, no more than 700 ppm, no more than 725 ppm, no more than 750 ppm, no more than 775 ppm, no more than 800 ppm, no more than 825 ppm, no more than 850 ppm, no more than 875 ppm, no more than 900 ppm, no more than 925 ppm, no more than 950 ppm, no more than 975 ppm, no more than 1000 ppm, no more than 1025 ppm, no more than 1050 ppm, no more than 1075 ppm, no more than 1100 ppm, no more than 1125 ppm, no more than 1150 ppm, no more than 1175 ppm, no more than 1200 ppm, no more

1225 ppm, no more than 1250 ppm, no more than 1275 ppm, no more than 1300 ppm, no more than 1325 ppm, no more

1350 ppm, no more than 1375 ppm, no more than 1400 ppm, no more than 1425 ppm, no more than 1450 ppm, no more

1475 ppm, no more than 1500 ppm, no more than 1600 ppm, no more than 1700 ppm, no more than 1800 ppm, no more

1900 ppm or not more than 2000 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount, for example, from about 0.5 ppm to about 20 ppm, from about 0.5 ppm to about 25 ppm, from about 0.5 ppm to about 30 ppm, from about 0.5 ppm to about 35 ppm, from about 0.5 ppm to about 40 ppm, from about 0.5 ppm to about 45 ppm, from about 0.5 ppm to about 50 ppm, from about 0.5 ppm to about 55 ppm, from about 0.5 ppm to about 60 ppm, from about 0.5 ppm to about 65 ppm, from about 0.5 ppm to about 70 ppm, from about 0.5 ppm to about 75 ppm, from about 0.5 ppm to about 80 ppm, from about 0.5 ppm to about 85 ppm, from about 0.5 ppm to about 90 ppm, from about 0.5 ppm to about 95 ppm, from about 0.5 ppm to about 100 ppm, from about 0.75 ppm to about 20 ppm, from about 0.75 ppm to about 25 ppm, from about 0.75 ppm to about 30 ppm, from about 0.75 ppm to about 35 ppm, from about 0.75 ppm to about 40 ppm, from about 0.75 ppm to about 45 ppm, from about 0.75 ppm to about 50 ppm, from about 0.75 ppm to about 55 ppm, from about 0 .75 ppm to about 60 ppm, from about 0.75 ppm to about 65 ppm, from about 0.75 ppm to about 70 ppm, from about 0.75 ppm to about 75 ppm, from about 0.75 ppm to about 80 ppm, from about 0.75 ppm to about 85 ppm, from about 0.75 ppm to about 90 ppm, from about 0.75 ppm to about 95 ppm, from about 0.75 ppm to about 100 ppm, from about 1 ppm to about 20 ppm, from about 1 ppm to about 25 ppm, from about 1 ppm to about 30 ppm, from about 1 ppm to about 35 ppm, from about 1 ppm to about 40 ppm, from about 1 ppm to about 45 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 55 ppm, from about 1 ppm to about 60 ppm, from about 1 ppm to about 65 ppm, from about 1 ppm to about 70 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 80 ppm, from about 1 ppm to about 85 ppm, from about 1 ppm to about 90 ppm, from about 1 ppm to about 95 ppm, from about 1 ppm to about 100 ppm, from about 5 ppm to about 20 ppm, about 5 ppm to about 25 ppm, about 5 ppm to about 30 ppm, about 5 ppm to about 35 ppm, about 5 ppm to about 40 ppm, about 5 ppm to about 45 ppm, from about 5 ppm to about 50 ppm, from about 5 ppm to about 55 ppm, from about 5 ppm to about 60 ppm, from about 5 ppm to about 65 ppm, from about 5 ppm to about 70 ppm, from about 5 ppm to about 75 ppm, from about 5 ppm to about 80 ppm, from about 5 ppm to about 85 ppm, from about 5 ppm to about 90 ppm, from about 5 ppm to

- 31 043933 about 95 ppm, from about 5 ppm to about 100 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 25 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 35 ppm, from about 10 ppm to about 40 ppm, from about 10 ppm to about 45 ppm, from about 10 ppm to about 50 ppm, from about 10 ppm to about 55 ppm, from about 10 ppm to about 60 ppm, from about 10 ppm to about 65 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 75 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 85 ppm, from about 10 ppm to about 90 ppm , from about 10 ppm to about 95 ppm, or from about 10 ppm to about 100 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount, for example, from about 1 ppm to about 25 ppm, from about 1 ppm to about 50 ppm, from about 1 ppm to about 75 ppm, from about 1 ppm to about 100 ppm, about 1 ppm to about 125 ppm, about 1 ppm to about 150 ppm, about 1 ppm to about 175 ppm, about 1 ppm to about 200 ppm, about 1 ppm to about 225 ppm, from about 1 ppm to about 250 ppm, from about 1 ppm to about 275 ppm, from about 1 ppm to about 300 ppm, from about 1 ppm to about 325 ppm, from about 1 ppm to about 350 ppm, from about 1 ppm to about 375 ppm, about 1 ppm to about 400 ppm, about 10 ppm to about 25 ppm, about 10 ppm to about 50 ppm, about 10 ppm to about 75 ppm, about 10 ppm to about 100 ppm, from about 10 ppm to about 125 ppm, from about 10 ppm to about 150 ppm, from about 10 ppm to about 175 ppm, from about 10 ppm to about 200 ppm, from about 10 ppm to about 225 ppm, from about 10 ppm to about 250 ppm, from about 10 ppm to about 275 ppm, from about 10 ppm to about 300 ppm, from about 10 ppm to about 325 ppm, from about 10 ppm to about 350 ppm, from about 10 ppm to about 375 ppm , from about 10 ppm to about 400 ppm, from about 25 ppm to about 50 ppm, from about 25 ppm to about 75 ppm, from about 25 ppm to about 100 ppm, from about 25 ppm to about 125 ppm, from about 25 ppm to about 150 ppm, from about 25 ppm to about 175 ppm, from about 25 ppm to about 200 ppm, from about 25 ppm to about 225 ppm, from about 25 ppm to about 250 ppm, from about 25 ppm to about 275 ppm, from about 25 ppm to about 300 ppm, from about 25 ppm to about 325 ppm, from about 25 ppm to about 350 ppm, from about 25 ppm to about 375 ppm, from about 25 ppm to about 400 ppm, from about 50 ppm to about 75 ppm, from about 50 ppm to about 100 ppm, from about 50 ppm to about 125 ppm, from about 50 ppm to about 150 ppm, from about 50 ppm to about 175 ppm, from about 50 ppm to about 200 ppm, from about 50 ppm to about 225 ppm, about 50 ppm to about 250 ppm, about 50 ppm to about 275 ppm, about 50 ppm to about 300 ppm, about 50 ppm to about 325 ppm, about 50 ppm to about 350 ppm, from about 50 ppm to about 375 ppm, from about 50 ppm to about 400 ppm, from about 75 ppm to about 100 ppm, from about 75 ppm to about 125 ppm, from about 75 ppm to about 150 ppm, from about 75 ppm to about 175 ppm, about 75 ppm to about 200 ppm, about 75 ppm to about 225 ppm, about 75 ppm to about 250 ppm, about 75 ppm to about 275 ppm, about 75 ppm to about 300 ppm, from about 75 ppm to about 325 ppm, from about 75 ppm to about 350 ppm, from about 75 ppm to about 375 ppm, from about 75 ppm to about 400 ppm, from about 100 ppm to about 125 ppm, from about 100 ppm to about 150 ppm, from about 100 ppm to about 175 ppm, from about 100 ppm to about 200 ppm, from about 100 ppm to about 225 ppm, from about 100 ppm to about 250 ppm, from about 100 ppm to about 275 ppm , from about 100 ppm to about 300 ppm, from about 100 ppm to about 325 ppm, from about 100 ppm to about 350 ppm, from about 100 ppm to about 375 ppm, from about 100 ppm to about 400 ppm, from about 150 ppm to about 175 ppm, from about 150 ppm to about 200 ppm, from about 150 ppm to about 225 ppm, from about 150 ppm to about 250 ppm, from about 150 ppm to about 275 ppm, from about 150 ppm to about 300 ppm, from about 150 ppm to about 325 ppm, from about 150 ppm to about 350 ppm, from about 150 ppm to about 375 ppm, from about 150 ppm to about 400 ppm, from about 200 ppm to about 225 ppm, from about 200 ppm to from about 250 ppm, from about 200 ppm to about 275 ppm, from about 200 ppm to about 300 ppm, from about 200 ppm to about 325 ppm, from about 200 ppm to about 350 ppm, from about 200 ppm to about 375 ppm, from about 200 ppm to about 400 ppm, about 250 ppm to about 275 ppm, about 250 ppm to about 300 ppm, about 250 ppm to about 325 ppm, about 250 ppm to about 350 ppm, about 250 ppm to about 375 ppm, from about 250 ppm to about 400 ppm, from about 300 ppm to about 325 ppm, from about 300 ppm to about 350 ppm, from about 300 ppm to about 375 ppm, from about 300 ppm to about 400 ppm, from about 350 ppm to about 375 ppm, from about 350 ppm to about 400 ppm, or from about 375 ppm to about 400 ppm.

In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount, for example, from about 400 ppm to about

- 32 043933

500 ppm, from about 400 ppm to about 600 ppm, from about 400 ppm to about 700 ppm, from about 400 ppm to about 800 ppm, from about 400 ppm to about 900 ppm, from about 400 ppm to about 1000 ppm, from about 400 ppm to about 1100 ppm, from about 400 ppm to about 1200 ppm, from about 400 ppm to about 1300 ppm, from about 400 ppm to about 1400 ppm, from about 400 ppm to about 1500 ppm, from about 400 ppm to about 1600 ppm, from about 400 ppm to about 1700 ppm, from about 400 ppm to about 1800 ppm, from about 400 ppm to about 1900 ppm, from about 400 ppm to about 2000 ppm, from about 500 ppm to about 600 ppm, from about 500 ppm to about 700 ppm, from about 500 ppm to about 800 ppm, from about 500 ppm to about 900 ppm, from about 500 ppm to about 1000 ppm, from about 500 ppm to about 1100 ppm, from about 500 ppm to about 1200 ppm , from about 500 ppm to about 1300 ppm, from about 500 ppm to about 1400 ppm, from about 500 ppm to about 1500 ppm, from about 500 ppm to about 1600 ppm, from about 500 ppm to about 1700 ppm, from about 500 ppm to about 1800 ppm, from about 500 ppm to about 1900 ppm, from about 500 ppm to about 2000 ppm, from about 600 ppm to about 700 ppm, from about 600 ppm to about 800 ppm, from about 600 ppm to about 900 ppm, from about 600 ppm to about 1000 ppm, from about 600 ppm to about 1100 ppm, from about 600 ppm to about 1200 ppm, from about 600 ppm to about 1300 ppm, from about 600 ppm to about 1400 ppm, from about 600 ppm to from about 1500 ppm, from about 600 ppm to about 1600 ppm, from about 600 ppm to about 1700 ppm, from about 600 ppm to about 1800 ppm, from about 600 ppm to about 1900 ppm, from about 600 ppm to about 2000 ppm, from from about 700 ppm to about 800 ppm, from about 700 ppm to about 900 ppm, from about 700 ppm to about 1000 ppm, from about 700 ppm to about 1100 ppm, from about 700 ppm to about 1200 ppm, from about 700 ppm to about 1300 ppm, from about 700 ppm to about 1400 ppm, from about 700 ppm to about 1500 ppm, from about 700 ppm to about 1600 ppm, from about 700 ppm to about 1700 ppm, from about 700 ppm to about 1800 ppm, from about 700 ppm to about 1900 ppm, from about 700 ppm to about 2000 ppm, from about 800 ppm to about 900 ppm, from about 800 ppm to about 1000 ppm, from about 800 ppm to about 1100 ppm, from about 800 ppm to about 1200 ppm, from about 800 ppm to about 1300 ppm, from about 800 ppm to about 1400 ppm, from about 800 ppm to about 1500 ppm, from about 800 ppm to about 1600 ppm, from about 800 ppm to about 1700 ppm, from about 800 ppm to about 1800 ppm, from about 800 ppm to about 1900 ppm, from about 800 ppm to about 2000 ppm, from about 900 ppm to about 1000 ppm, from about 900 ppm to about 1100 ppm, from about 900 ppm to about 1200 ppm , from about 900 ppm to about 1300 ppm, from about 900 ppm to about 1400 ppm, from about 900 ppm to about 1500 ppm, from about 900 ppm to about 1600 ppm, from about 900 ppm to about 1700 ppm, from about 900 ppm to about 1800 ppm, from about 900 ppm to about 1900 ppm, from about 900 ppm to about 2000 ppm, from about 1000 ppm to about 1100 ppm, from about 1000 ppm to about 1200 ppm, from about 1000 ppm to about 1300 ppm, from about 1000 ppm to about 1400 ppm, from about 1000 ppm to about 1500 ppm, from about 1000 ppm to about 1600 ppm, from about 1000 ppm to about 1700 ppm, from about 1000 ppm to about 1800 ppm, from about 1000 ppm to about 1900 ppm, from about 1000 ppm to about 2000 ppm, from about 1100 ppm to about 1200 ppm, from about 1100 ppm to about 1300 ppm, from about 1100 ppm to about 1400 ppm, from about 1100 ppm to about 1500 ppm, from from about 1100 ppm to about 1600 ppm, from about 1100 ppm to about 1700 ppm, from about 1100 ppm to about 1800 ppm, from about 1100 ppm to about 1900 ppm, from about 1100 ppm to about 2000 ppm, from about 1200 ppm to about 1300 ppm, from about 1200 ppm to about 1400 ppm, from about 1200 ppm to about 1500 ppm, from about 1200 ppm to about 1600 ppm, from about 1200 ppm to about 1700 ppm, from about 1200 ppm to about 1800 ppm, from about 1200 ppm to about 1900 ppm, from about 1200 ppm to about 2000 ppm, from about 1300 ppm to about 1400 ppm, from about 1300 ppm to about 1500 ppm, from about 1300 ppm to about 1600 ppm, from about 1300 ppm to about 1700 ppm, from about 1300 ppm to about 1800 ppm, from about 1300 ppm to about 1900 ppm, from about 1300 ppm to about 2000 ppm, from about 1400 ppm to about 1500 ppm, from about 1400 ppm to about 1600 ppm, from about 1400 ppm to about 1700 ppm, from about 1400 ppm to about 1800 ppm, from about 1400 ppm to about 1900 ppm, from about 1400 ppm to about 2000 ppm, from about 1500 ppm to about 1600 ppm, from about 1500 ppm to about 1700 ppm , from about 1500 ppm to about 1800 ppm, from about 1500 ppm to about 1900 ppm, from about 1500 ppm to about 2000 ppm, from about 1600 ppm to about 1700 ppm, from about 1600 ppm to about 1800 ppm, from about 1600 ppm to about 1900 ppm, from about 1600 ppm to about 2000 ppm, from about 1700 ppm to about 1800 ppm, from about 1700 ppm to about 1900 ppm, from about 1700 ppm to about 2000 ppm, from about 1800 ppm to about 1900 ppm, from about 1800 ppm to about 2000 ppm or from about 1900 ppm to about 2000 ppm.

In aspects according to the specified embodiment, the composition described in the present invention

- 33 043933 tenii, contains a metal salt in an amount of, for example, about 0.10%, about 0.11%, about 0.12%, about 0.13%, about 0.14%, about 0.15%, about 0.16%, approximately 0.17%, approximately 0.18%, approximately 0.19%, approximately 0.2%, approximately 0.25%, approximately 0.3%, approximately 0.35%, approximately 0. 4%, about 0.45%, or about 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, at least 0.10%, at least 0.11%, at least 0.12%, at least 0 .13%, at least 0.14%, at least 0.15%, at least 0.16%, at least 0.17%, at least 0.18%, at least 0.19 %, at least 0.2%, at least 0.25%, at least 0.3%, at least 0.35%, at least 0.4%, at least 0.45% or at least 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, no more than 0.10%, no more than 0.11%, no more than 0.12%, no more than 0.13%, not more than 0.14%, not more than 0.15%, not more than 0.16%, not more than 0.17%, not more than 0.18%, not more than 0.19%, not more than 0.2%, not more than 0.25%, no more than 0.3%, no more than 0.35%, no more than 0.4%, no more than 0.45% or no more than 0.5% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a metal salt in an amount of, for example, from about 0.10% to about 0.15%, from about 0.10% to about 0.20%, from about 0.10% to about 0.25%, from about 0.10% to about 0.30%, from about 0.10% to about 0.35%, from about 0.10% to about 0.40%, from about 0.10% to about 0.45%, from about 0.10% to about 0.50%, from about 0.20% to about 0.25%, from about 0.20% to about 0.30 %, from about 0.20% to about 0.35%, from about 0.20% to about 0.40%, from about 0.20% to about 0.45%, from about 0.20% to about 0 .50%, from about 0.30% to about 0.35%, from about 0.30% to about 0.40%, from about 0.30% to about 0.45%, from about 0.30% to about 0.50%, about 0.40% to about 0.45%, or about 0.40% to about 0.50% by weight of the composition.

In one embodiment, the composition described in the present invention does not contain metal salts.

The composition described in the present invention may contain a carrier. The carrier, also known as a carrier material, can be any material commonly known in the fields of skin care, cosmetics and medicine, which is used as a basis for preparing the composition described in the present invention. The carrier may be an aqueous carrier, a semi-solid carrier, or a solid carrier. The carrier can also provide skin care as described in the present invention. The carrier includes, but is not limited to, water, vegetable oil, mineral oil, essential oil, ether, alcohol, fatty alcohol, isoparaffin, hydrocarbon oil, polyhydric alcohol and wax. Non-limiting examples of essential oils include octyl palmitate, isopropyl myristate and isopropyl palmitate. Non-limiting examples of ethers include dicaprylic ether and dimethyl isosorbide. Non-limiting examples of alcohols include ethanol and isopropanol. Non-limiting examples of fatty alcohols include cetyl alcohol, cetearyl alcohol, stearyl alcohol and behenyl alcohol. Non-limiting examples of isoparaffins include isooctane, isododecane (IDD), and isohexadecane. Non-limiting examples of hydrocarbon oils include mineral oil, petrolatum, isoeicosane and polyolefin, including (hydrogenated) polyisobutene. Non-limiting examples of polyhydric alcohols include propylene glycol, glycerin, butylene glycol, pentylene glycol, hexylene glycol, caprylyl glycol. Non-limiting examples of waxes include beeswax, carnauba wax, ozokerite, microcrystalline wax, polyethylene wax and botanical wax.

In one embodiment, the composition described in the present invention contains a single carrier. In another embodiment, the composition described in the present invention contains a plurality of carriers. In aspects according to this embodiment, the composition described in the present invention contains, for example, one or more carriers, two or more carriers, three or more carriers, four or more carriers, or five or more carriers. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, only one carrier, at most two carriers, at most three carriers, at most four carriers, or at most five carriers. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, from 1 to 2 carriers, from 1 to 3 carriers, from 1 to 4 carriers, from 1 to 5 carriers, from 2 to 3 carriers, from 2 up to 4 media, 2 to 5 media, 3 to 4 media, 3 to 5 media, or 4 to 5 media.

In another embodiment, the composition described in the present invention contains an amount of carrier that provides the desired formulation or beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains a carrier in an amount of, for example, at least 5%, at least 10%, at least 15%, at least 20%, at least 25%, at least 30%, at least 35%, at least 40%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least at least 70%, at least

- 34 043933 at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or according at least 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a carrier in an amount of, for example, no more than 5%, no more than 10%, no more than 15%, no more than 20%, no more than 25%, no more than 30% , no more than 35%, no more than 40%, no more than 45%, no more than 50%, no more than 55%, no more than 60%, no more than 65%, no more than 70%, no more than 75%, no more than 80% , not more than 85%, not more than 90%, not more than 95%, not more than 96%, not more than 97%, not more than 98% or not more than 99% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains a carrier in an amount of, for example, from about 5% to about 25%, from about 5% to about 50%, from about 5% to about 75%, from about 5% to about 90%, from about 5% to about 95%, from about 5% to about 96%, from about 5% to about 97%, from about 5% to about 98%, from about 5% to about 99 %, from about 25% to about 50%, from about 25% to about 75%, from about 25% to about 90%, from about 25% to about 95%, from about 25% to about 96%, from about 25 % to about 97%, from about 25% to about 98%, from about 25% to about 99%, from about 50% to about 75%, from about 50% to about 90%, from about 50% to about 95% , from about 50% to about 96%, from about 50% to about 97%, from about 50% to about 98%, from about 50% to about 99%, from about 75% to about 80%, from about 75% to about 85%, from about 75% to about 90%, from about 75% to about 95%, from about 75% to about 96%, from about 75% to about 97%, from about 75% to about 98%, from about 75% to about 99%, from about 80% to about 85%, from about 80% to about 90%, from about 80% to about 95%, from about 80% to about 96%, from about 80% to about 97%, from about 80% to about 98%, from about 80% to about 99%, from about 85% to about 90%, from about 85% to about 95%, from about 85% to about 96%, from about 85% to about 97%, about 85% to about 98%, about 85% to about 99%, about 90% to about 95%, about 90% to about 96%, about 90% to about 97%, from about 90% to about 98%, from about 90% to about 99%, or from about 95% to about 99% by weight of the composition.

In another embodiment, the composition described in the present invention contains a carrier other than alcohol. In aspects according to this embodiment, if the composition described in the present invention contains hypochlorous acid or free active chlorine, then the composition may contain a carrier other than an alcohol.

The composition described in the present invention may further optionally include additional ingredients. An additional ingredient is an ingredient useful in preparing the final composition described in the present invention. The additional ingredient includes, but is not limited to, a hydrophilic clay, a disinfectant, an antiseptic, a surfactant, a preservative, or a chelating agent. The additional ingredient described in the present invention is known in the art.

Hydrophilic clay is a synthetic or natural smectic clay that, when hydrated, forms three-dimensional colloidal structures, resulting in increased viscosity and improved suspension control components in the composition. Hydrophilic clay includes hydrous phyllosilicate clays. Hydrophilic clay may have thixotropic properties. Non-limiting examples of hydrophilic clays include bentonite clay, hectorite clay, kaolinite clay and silicate clay. Bentonite clay is a phyllosilicate clay and includes, but is not limited to, potassium bentonite clay, soda bentonite clay, calcium bentonite clay and aluminum bentonite clay. Hectorite clay is a phyllosilicate clay and includes clays sold commercially as the BENTONE® product line, including hectorite clay (BENTONE® EW), hectorite clay (BENTONE® MA) and hectorite clay and hydroxyethylcellulose (BENTONE® LT). Kaolinite clay is a phyllosilicate clay. Silicate clay is a synthetic layered silicate clay and includes clays sold commercially as the LAPONITE® product line, including lithium magnesium sodium silicate (LAPONITE® XLG), lithium magnesium sodium silicate and tetrasodium pyrophosphate (LAPONITE® XLS), fluorosilicate sodium magnesium (LAPONITE® XL) and sodium magnesium fluorosilicate (LAPONITE® XL21).

In one embodiment, the composition described in the present invention contains one hydrophilic clay. In another embodiment, the composition described in the present invention contains a plurality of hydrophilic clays. In aspects according to this embodiment, the composition described in the present invention contains, for example, one or more hydrophilic clays, two or more hydrophilic clays, three or more hydrophilic clays, four or more hydrophilic clays, or five or more hydrophilic clays. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, only one hydrophilic clay, no more than two hydrophilic clays, no more than three hydrophilic clays, no more than four

- 35 043933 hydrophilic clays or no more than five hydrophilic clays. In other aspects, according to this embodiment, the composition described in the present invention contains, for example, from 1 to 2 hydrophilic clays, from 1 to 3 hydrophilic clays, from 1 to 4 hydrophilic clays, from 1 to 5 hydrophilic clays, from 2 to 3 hydrophilic clays, 2 to 4 hydrophilic clays, 2 to 5 hydrophilic clays, 3 to 4 hydrophilic clays, 3 to 5 hydrophilic clays or 4 to 5 hydrophilic clays.

In another embodiment, the composition described in the present invention contains hydrophilic clay in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains hydrophilic clay in an amount of, for example, 0.01%, 0.025%, 0.05%, 0.075%, 0.1%, 0.2%, 0.25 %, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.75%, 0.8%, 0.9%, 1%, 2%, 3% , 4%, 5%, 6%, 7%, 8%. 9% or 10% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains hydrophilic clay in an amount of, for example, at least 0.01%, at least 0.025%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5%, at least 0.75%, at least 1%, at least 2%, at least 3%, at least 4%, at least 5%, at least 6%, at least 7%, at least 8%, at least 9% or at least 10% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains hydrophilic clay in an amount of, for example, no more than 0.01%, no more than 0.025%, no more than 0.05%, no more than 0.075%, no more than 0. 1%, no more than 0.25%, no more than 0.5%, no more than 0.75%, no more than 1%, no more than 2%, no more than 3%, no more than 4%, no more than 5%, not more than 6%, no more than 7%, no more than 8%, no more than 9% or no more than 10% by weight of the composition.

In other aspects, according to this embodiment, the composition described in the present invention contains hydrophilic clay in an amount, for example, from about 0.01% to about 0.05%, 0.01% to about 0.075%, from about 0.01% to about 0.1%, from about 0.1% to about 0.5%, from about 0.1% to about 0.75%, from about 0.1% to about 1%, from about 0.1% to about 2%, from about 0.1% to about 3%, from about 0.1% to about 4%, from about 0.1% to about 5%, from about 0.1% to about 6%, from about 0.1% to about 7%, about 0.1% to about 8%, about 0.1% to about 9%, about 0.1% to about 10%, about 0.25% to about 0.5%, about 0.25% to about 0.75%, about 0.25% to about 1%, about 0.25% to about 2%, about 0.25% to about 3 %, from about 0.25% to about 4%, from about 0.25% to about 5%, from about 0.25% to about 6%, from about 0.25% to about 7%, from about 0. 25% to about 8%, from about 0.25% to about 9%, from about 0.25% to about 10%, from about 0.5% to about 0.75%, from about 0.5% to about 1%, from about 0.5% to about 2%, from about 0.5% to about 3%, from about 0.5% to about 4%, from about 0.5% to about 5%, from about 0 .5% to about 6%, from about 0.5% to about 7%, from about 0.5% to about 8%, from about 0.5% to about 9%, from about 0.5% to about 10 %, from about 0.75% to about 1%, from about 0.75% to about 2%, from about 0.75% to about 3%, from about 0.75% to about 4%, from about 0. 75% to about 5%, about 0.75% to about 6%, about 0.75% to about 7%, about 0.75% to about 8%, about 0.75% to about 9% , from about 0.75% to about 10%, from about 1% to about 2%, from about 1% to about 3%, from about 1% to about 4%, from about

1% to about 5%, from about 1% to about 6%, from about 1% to about 7%, from about

1% to about 8%, about 1% to about 9%, about 1% to about 10%, about 2% to about 3%, about 2% to about 4%, about 2% to about 5 %, from approximately

2% to about 6%, from about 2% to about 7%, from about 2% to about 8%, from about

2% to about 9%, about 2% to about 10%, about 3% to about 4%, about 3% to about 5%, about 3% to about 6%, about 3% to about 7 %, from about 3% to about 8%, from about 3% to about 9%, from about 3% to about 10%, from about 4% to about 5%, from about 4% to about 6%, from about 4 % to about 7%, from about 4% to about 8%, from about 4% to about 9%, from about 4% to about 10%, from about 5% to about 6%, from about 5% to about 7% , from about 5% to about 8%, from about 5% to about 9%, from about 5% to about 10%, from about 6% to about 7%, from about 6% to about 8%, from about 6% to about 9%, from about 6% to about 10%, from about 7% to about 8%, from about 7% to about 9%, from about 7% to about 10%, from about 8% to about 9%, from about 8% to about 10% or from about 9% to about 10% by weight of the composition.

In another embodiment, the composition described in the present invention contains silicate clay in an amount that imparts the desired beneficial effect of the composition described in the present invention. In aspects according to this embodiment, the composition described in the present invention contains silicate clay in an amount of, for example, 0.001%, 0.0025%, 0.005%, 0.0075%, 0.01%, 0.025%, 0.05%, 0.075%, 0.1%, 0.2%, 0.25%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.75%, 0, 8%, 0.9%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%. 9% or 10% by weight of the composition. In other aspects according to

- 36 043933 to the specified embodiment, the composition described in the present invention contains silicate clay in an amount of, for example, at least 0.001%, at least 0.0025%, at least 0.005%, at least 0.0075%, according to at least 0.01%, at least 0.025%, at least 0.05%, at least 0.075%, at least 0.1%, at least 0.25%, at least 0.5% , at least 0.75%, at least 1%, at least 2%, at least 3%, at least 4%, at least 5%, at least 6%, at least 7% , at least 8%, at least 9% or at least 10% by weight of the composition. In other aspects, according to this embodiment, the composition described in the present invention contains silicate clay in an amount of, for example, no more than 0.001%, no more than 0.0025%, no more than 0.005%, no more than 0.0075%, no more than 0. 01%, no more than 0.025%, no more than 0.05%, no more than 0.075%, no more than 0.1%, no more than 0.25%, no more than 0.5%, no more than 0.75%, no more 1%, not more than 2%, not more than 3%, not more than 4%, not more than 5%, not more than 6%, not more than 7%, not more than 8%, not more than 9% or not more than 10% by weight of the composition .

In other aspects, according to this embodiment, the composition described in the present invention contains silicate clay in an amount, for example, from about 0.001% to about 0.005%, from about 0.001% to about 0.0075%, from about 0.001% to about 0. 01%, from about 0.001% to about 0.05%, from about 0.001% to about 0.075%, from about 0.001% to about 0.1%, from about 0.001% to about 0.25%, from about 0.001% to about 0.5%, from about 0.001% to about 0.75%, from about 0.005% to about 0.0075%, from about 0.005% to about 0.01%, from about 0.005% to about 0.05%, from about 0.005% to about 0.075%, from about 0.005% to about 0.1%, from about 0.005% to about 0.25%, from about 0.005% to about 0.5%, from about 0.005% to about 0, 75%, about 0.01% to about 0.05%, 0.01% to about 0.075%, about 0.01% to about 0.1%, about 0.1% to about 0.5% , from about 0.1% to about 0.75%, from about 0.1% to about 1%, from about 0.1% to about 2%, from about 0.1% to about 3%, from about 0 .1% to about 4%, from about 0.1% to about 5%, from about 0.1% to about 6%, from about 0.1% to about 7%, from about 0.1% to about 8 %, from about 0.1% to about 9%, from about 0.1% to about 10%, from about 0.25% to about 0.5%, from about 0.25% to about 0.75%, from about 0.25% to about 1%, from about 0.25% to about 2%, from about 0.25% to about 3%, from about 0.25% to about 4%, from about 0.25% to about 5%, from about 0.25% to about 6%, from about 0.25% to about 7%, from about 0.25% to about 8%, from about 0.25% to about 9%, from about 0.25% to about 10%, from about 0.5% to about 0.75%, from about 0.5% to about 1%, from about 0.5% to about 2%, from about 0.5 % to about 3%, from about 0.5% to about 4%, from about 0.5% to about 5%, from about 0.5% to about 6%, from about 0.5% to about 7%, from about 0.5% to about 8%, from about 0.5% to about 9%, from about 0.5% to about 10%, from about 0.75% to about 1%, from about 0.75% to about 2%, from about 0.75% to about 3%, from about 0.75% to about 4%, from about 0.75% to about 5%, from about 0.75% to about 6%, from about 0.75% to about 7%, about 0.75% to about 8%, about 0.75% to about 9%, about 0.75% to about 10%, about 1% to about 2 %, from about 1% to about 3%, from about 1% to about 4%, from about 1% to about

5%, from about 1% to about 6%, from about 1% to about 7%, from about 1% to about

8%, from about 1% to about 9%, from about 1% to about 10%, from about 2% to about 3%, from about 2% to about 4%, from about 2% to about 5%, from about 2% to approx.

6%, from about 2% to about 7%, from about 2% to about 8%, from about 2% to about

9%, from about 2% to about 10%, from about 3% to about 4%, from about 3% to about 5%, from about 3% to about 6%, from about 3% to about 7%, from about 3% to about 8%, about 3% to about 9%, about 3% to about 10%, about 4% to about 5%, about 4% to about 6%, about 4% to about 7 %, from about 4% to about 8%, from about 4% to about 9%, from about 4% to about 10%, from about 5% to about 6%, from about 5% to about 7%, from about 5 % to about 8%, from about 5% to about 9%, from about 5% to about 10%, from about 6% to about 7%, from about 6% to about 8%, from about 6% to about 9% , from about 6% to about 10%, from about 7% to about 8%, from about 7% to about 9%, from about 7% to about 10%, from about 8% to about 9%, from about 8% to about 10% or from about 9% to about 10% by weight of the composition.

The preservative maintains the stability of the composition described in the present invention. The preservative may also prevent the growth of microorganisms in the composition described in the present invention. Non-limiting examples of preservatives include methylparaben, phenoxyethanol, capryl glycol, glyceryl caprylate, benzoic acid, sorbic acid, gallic acid and propylparaben.

The pH of the composition described in the present invention can be adjusted to any pH that allows the composition described in the present invention to achieve the desired beneficial effect. In aspects according to this embodiment, the pH of the composition described in the present invention is, for example, at least 2, at least 3, at least 4, at least 5, at least 6, at least 7, at least at least 8, at least 9, at least 10

- 37 043933 or at least 11. In other aspects, according to this embodiment, the pH of the composition described in the present invention is, for example, no more than 2, no more than 3, no more than 4, no more than 5, no more than 6, no more 7, no more than 8, no more than 9, no more than 10 or no more than 11.

In other aspects, according to this embodiment, the pH of the composition described in the present invention is, for example, from about 2 to about 5, from about 2 to about 5.5, from about 2 to about 6, from about 2 to about 6.5 , from about 2 to about 7, from about 2 to about 7.5, from about 2 to about 8, from about 2 to about 8.5, from about 2 to about 9, from about 2.5 to about 5, from about 2.5 to about 5.5, about 2.5 to about 6, about 2.5 to about 6.5, about 2.5 to about 7, about 2.5 to about 7.5, from about 2.5 to about 8, from about 2.5 to about 8.5, from about 2.5 to about 9, from about 3 to about 5, from about 3 to about 5.5, from about 3 to about 6, from about 3 to about 6.5, from about 3 to about 7, from about 3 to about 7.5, from about 3 to about 8, from about 3 to about 8.5, from about 3 to about 9, from about 3.5 to about 5, from about 3.5 to about 5.5, from about 3.5 to about 6, from about 3.5 to about 6.5, from about 3.5 to about 7, from about 3.5 to about 7.5, about 3.5 to about 8, about 3.5 to about 8.5, about 3.5 to about 9, about 4 to about 5, about 4 to about 5.5, about 4 to about 6, about 4 to about 6.5, about 4 to about 7, about 4 to about 7.5, about 4 to about 8, about 4 to about 8 .5, from about 4 to about 9, from about 4.5 to about 5, from about 4.5 to about 5.5, from about 4.5 to about 6, from about 4.5 to about 6.5, from about 4.5 to about 7, from about 4.5 to about 7.5, from about 4.5 to about 8, from about 4.5 to about 8.5, from about 4.5 to about 9, from about 5 to about 5.5, about 5 to about 6, about 5 to about 6.5, about 5 to about 7, about 5 to about 7.5, about 5 to about 8, about 5 to about 8.5, from about 5 to about 9, from about 5.5 to about 6, from about 5.5 to about 6.5, from about 5.5 to about 7, from about 5.5 to about 7 .5, from about 5.5 to about 8, from about 5.5 to about 8.5, from about 5.5 to about 9, from about 6 to about 6.5, from about 6 to about 7, from about 6 to about 7.5, about 6 to about 8, about 6 to about 8.5, about 6 to about 9, about 6.5 to about 7, about 6.5 to about 7.5, from about 6.5 to about 8, from about 6.5 to about 8.5, from about 6.5 to about 9, from about 7 to about 7.5, from about 7 to about 8, from about 7 to about 8.5, from about 7 to about 9, from about 7.5 to about 8, from about 7.5 to about 8.5, from about 7.5 to about 9, from about 8 to about 8.5, from about 8 to about 9 or about 8.5 to about 9.

The composition described in the present invention is resistant to inactivation by exposure to body fluids. A body fluid is a fluid containing charged molecules and includes, but is not limited to, blood and blood-based byproducts such as plasma and serum. In one embodiment, a composition described in the present invention is resistant to inactivation when it exhibits, for example, no more than 1% inactivation, no more than 2% inactivation, no more than 3% inactivation, no more than 4% inactivation, no more than 5 % inactivation, no more than 6% inactivation, no more than 7% inactivation, no more than 8% inactivation, no more than 9% inactivation, or no more than 10% inactivation when exposed to body fluids. In another embodiment, a composition described in the present invention is resistant to inactivation when it exhibits, for example, no more than 10% inactivation, no more than 15% inactivation, no more than 20% inactivation, no more than 25% inactivation, no more than 30% inactivation, no more than 35% inactivation, no more than 40% inactivation, no more than 45% inactivation, no more than 50% inactivation under the influence of body fluids. In another embodiment, a composition described herein is resistant to inactivation when it exhibits, for example, about 1% to about 10% inactivation, about 1% to about 20% inactivation, about 1% to about 30% inactivation, from about 1% to about 40% inactivation, from about 1% to about 50% inactivation, from about 5% to about 10% inactivation, from about 5% to about 20% inactivation, from about 5% to about 30% inactivation, about 5% to about 40% inactivation, about 5% to about 50% inactivation, about 10% to about 20% inactivation, about 10% to about 30% inactivation, about 10% to about 40% inactivation, about 10% to about 50% inactivation, 20% to about 30% inactivation, about 20% to about 40% inactivation, about 20% to about 50% inactivation, about 30% to about 40% inactivation, from about 30% to about 50% inactivation or from about 40% to about 50% inactivation by exposure to body fluids.

In one embodiment, a composition described in the present invention is resistant to inactivation when it exhibits, for example, no more than 1% degradation, no more than 2% degradation, no more than 3% degradation, no more than 4% degradation, no more than 5 % decomposition, not more than 6% decomposition, not more than 7% decomposition, not more than 8% decomposition, not more than 9% decomposition, or not more than 10% decomposition of hypochlorous acid when exposed to physiological fluid. In another version

- 38 043933 implementations of the composition described in the present invention is resistant to inactivation when it exhibits, for example, no more than 10% degradation, no more than 15% degradation, no more than 20% degradation, no more than 25% degradation, no more than 30% decomposition, no more than 35% decomposition, no more than 40% decomposition, no more than 45% decomposition, no more than 50% decomposition of hypochlorous acid under the influence of physiological fluid. In another embodiment, a composition described in the present invention is resistant to inactivation when it exhibits, for example, from about 1% to about 10% degradation, from about 1% to about 20% degradation, from about 1% to about 30% degradation, about 1% to about 40% degradation, about 1% to about 50% degradation, about 5% to about 10% degradation, about 5% to about 20% degradation, about 5% to about 30% decomposition, about 5% to about 40% decomposition, about 5% to about 50% decomposition, about 10% to about 20% decomposition, about 10% to about 30% decomposition, about 10% to about 40% decomposition, about 10% to about 50% decomposition, 20% to about 30% decomposition, about 20% to about 40% decomposition, about 20% to about 50% decomposition, about 30% to about 40% decomposition, from about 30% to about 50% degradation or from about 40% to about 50% degradation of hypochlorous acid when exposed to physiological fluid.

The composition described in the present invention is stable. In one embodiment, a composition described in the present invention is stable when it exhibits, for example, no more than 1% degradation, no more than 2% degradation, no more than 3% degradation, no more than 4% degradation, no more than 5% degradation , not more than 6% decomposition, not more than 7% decomposition, not more than 8% decomposition, not more than 9% decomposition or not more than 10% decomposition of hypochlorous acid. In another embodiment, a composition described in the present invention is stable when it exhibits, for example, no more than 10% degradation, no more than 15% degradation, no more than 20% degradation, no more than 25% degradation, no more than 30% degradation, no more than 35% decomposition, no more than 40% decomposition, no more than 45% decomposition, no more than 50% decomposition, no more than 55% decomposition, no more than 60% decomposition, no more than 65% decomposition, no more than 70% decomposition, no more 75% decomposition, no more than 80% decomposition, no more than 85% decomposition, no more than 90% decomposition, or no more than 95% decomposition of hypochlorous acid. In another embodiment, a composition described in the present invention is stable when it exhibits, for example, from about 1% to about 10% degradation, from about 1% to about 20% degradation, from about 1% to about 30% degradation, from about 1% to about 40% degradation, from about 1% to about 50% degradation, from about 1% to about 60% degradation, from about 1% to about 70% degradation, from about 1% to about 80% degradation, from about 1% to about 90% degradation, from about 1% to about 95% degradation, from about 5% to about 10% degradation, from about 5% to about 20% degradation, from about 5% to about 30% degradation, about 5% to about 40% degradation, about 5% to about 50% degradation, about 5% to about 60% degradation, about 5% to about 70% degradation, about 5% to about 80% degradation, from about 5% to about 90% degradation, from about 5% to about 95% degradation, from about 10% to about 20% degradation, from about 10% to about 30% degradation, from about 10% to about 40% degradation, from about 10% to about 50% degradation, from about 10% to about 60% degradation, from about 10% to about 70% degradation, from about 10% to about 80% degradation, from about 10% to about 90% degradation, about 10% to about 95% degradation, 20% to about 30% degradation, about 20% to about 40% degradation, about 20% to about 50% degradation, about 20% to about 60% degradation, about 20% to about 70% degradation, about 20% to about 80% degradation, about 20% to about 90% degradation, about 20% to about 95% degradation, about 30% to about 40% degradation, about 30% to about 50% degradation, about 30% to about 60% degradation, about 30% to about 70% degradation, about 30% to about 80% degradation, about 30% to about 90% degradation, about 30% to about 95% degradation, about 40% to about 50% degradation, about 40% to about 60% degradation, about 40% to about 70% degradation, about 40% to about 80% degradation, about 40% to about 90% degradation, about 40% to about 95% degradation, about 50% to about 60% degradation, about 50% to about 70% degradation, about 50% to about 80% degradation, about 50% to about 90% degradation, about 50% to about 95% degradation, about 60% to about 70% degradation, about 60% to about 80% degradation, about 60% to about 90% degradation, about 60% to about 95% degradation, about 70% to about 80% degradation, about 70% to about 90% degradation, about 70% to about 95% degradation, about 80% to about 90% degradation, about 80% to about 95% degradation or about 90% to about 95% degradation of hypochlorous acid.

In one embodiment, a composition described in the present invention is stable when it exhibits, for example, no more than 1% degradation, no more than 2% degradation, no more

- 39 043933 more than 3% decomposition, no more than 4% decomposition, no more than 5% decomposition, no more than 6% decomposition, no more than 7% decomposition, no more than 8% decomposition, no more than 9% decomposition or no more than 10% free decomposition active chlorine. In another embodiment, a composition described in the present invention is stable when it exhibits, for example, no more than 10% degradation, no more than 15% degradation, no more than 20% degradation, no more than 25% degradation, no more than 30% degradation, no more than 35% decomposition, no more than 40% decomposition, no more than 45% decomposition, no more than 50% decomposition, no more than 55% decomposition, no more than 60% decomposition, no more than 65% decomposition, no more than 70% decomposition, no more 75% decomposition, no more than 80% decomposition, no more than 85% decomposition, no more than 90% decomposition, or no more than 95% decomposition of free active chlorine. In another embodiment, a composition described in the present invention is stable when it exhibits, for example, from about 1% to about 10% degradation, from about 1% to about 20% degradation, from about 1% to about 30% degradation, from about 1% to about 40% degradation, from about 1% to about 50% degradation, from about 1% to about 60% degradation, from about 1% to about 70% degradation, from about 1% to about 80% degradation, from about 1% to about 90% degradation, from about 1% to about 95% degradation, from about 5% to about 10% degradation, from about 5% to about 20% degradation, from about 5% to about 30% degradation, about 5% to about 40% degradation, about 5% to about 50% degradation, about 5% to about 60% degradation, about 5% to about 70% degradation, about 5% to about 80% degradation, from about 5% to about 90% degradation, from about 5% to about 95% degradation, from about 10% to about 20% degradation, from about 10% to about 30% degradation, from about 10% to about 40% degradation, from about 10% to about 50% degradation, from about 10% to about 60% degradation, from about 10% to about 70% degradation, from about 10% to about 80% degradation, from about 10% to about 90% degradation, about 10% to about 95% degradation, 20% to about 30% degradation, about 20% to about 40% degradation, about 20% to about 50% degradation, about 20% to about 60% degradation, about 20% to about 70% degradation, about 20% to about 80% degradation, about 20% to about 90% degradation, about 20% to about 95% degradation, about 30% to about 40% degradation, about 30% to about 50% degradation, about 30% to about 60% degradation, about 30% to about 70% degradation, about 30% to about 80% degradation, about 30% to about 90% degradation, about 30% to about 95% degradation, about 40% to about 50% degradation, about 40% to about 60% degradation, about 40% to about 70% degradation, about 40% to about 80% degradation, about 40% to about 90% degradation, about 40% to about 95% degradation, about 50% to about 60% degradation, about 50% to about 70% degradation, about 50% to about 80% degradation, about 50% to about 90% degradation, about 50% to about 95% degradation, about 60% to about 70% degradation, about 60% to about 80% degradation, about 60% to about 90% degradation, about 60% to about 95% degradation, about 70% to about 80% degradation, about 70% to about 90% degradation, about 70% to about 95% degradation, about 80% to about 90% degradation, about 80% to about 95% decomposition or about 90% to about 95% decomposition of free active chlorine.

In aspects according to this embodiment, the composition described in the present invention is stable for, for example, about 1 day, about 2 days, 3 days, 4 days, 5 days, 6 days, 7 days, 8 days, 9 days, 10 days, 11 days, 12 days, 13 days, 14 days or 15 days. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, at least 1 day, at least 2 days, at least 3 days, at least 4 days, at least 5 days , at least 6 days, at least 7 days, at least 8 days, at least 9 days, at least 10 days, at least 11 days, at least 12 days, at least 13 days, according to at least 14 days or at least 15 days. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, no more than 1 day, no more than 2 days, no more than 3 days, no more than 4 days, no more than 5 days, no more than 6 days , no more than 7 days, no more than 8 days, no more than 9 days, no more than 10 days, no more than 11 days, no more than 12 days, no more than 13 days, no more than 14 days or no more than 15 days.

In other aspects of this embodiment, the composition described in the present invention is stable for, for example, from about 1 day to about 2 days, from about 1 day to about 3 days, from about 1 day to about 4 days, from about 1 days to about 5 days, about 1 day to about 6 days, about 1 day to about 7 days, about 1 day to about 8 days, about 1 day to about 9 days, about 1 day to about 10 days , from about 1 day to about 11 days, from about 1 day to about 12 days, from about 1 day to about 13 days, from about 1 day to about 14 days, from about 1 day to about 15 days, from about 2 days up to about 3 days, from about 2 days to about 4 days, from about 2 days to at

- 40 043933 approximately 5 days, from about 2 days to about 6 days, from about 2 days to about 7 days, from about 2 days to about 8 days, from about 2 days to about 9 days, from about 2 days to about 10 days, from about 2 days to about 11 days, from about 2 days to about 12 days, from about 2 days to about 13 days, from about 2 days to about 14 days, from about 2 days to about 15 days, from about 3 days to about 4 days, about 3 days to about 5 days, about 3 days to about 6 days, about 3 days to about 7 days, about 3 days to about 8 days, about 3 days to about 9 days , from about 3 days to about 10 days, from about 3 days to about 11 days, from about 3 days to about 12 days, from about 3 days to about 13 days, from about 3 days to about 14 days, from about 3 days to about 15 days, from about 4 days to about 5 days, from about 4 days to about 6 days, from about 4 days to about 7 days, from about 4 days to about 8 days, from about 4 days to about 9 days, from about 4 days to about 10 days, from about 4 days to about 11 days, from about 4 days to about 12 days, from about 4 days to about 13 days, from about 4 days to about 14 days, from about 4 days to about 15 days, from about 5 days to about 6 days, from about 5 days to about 7 days, from about 5 days to about 8 days, from about 5 days to about 9 days, from about 5 days to about 10 days, from about 5 days to about 11 days, about 5 days to about 12 days, about 5 days to about 13 days, about 5 days to about 14 days, about 5 days to about 15 days, about 6 days to about 7 days, from about 6 days to about 8 days, from about 6 days to about 9 days, from about 6 days to about 10 days, from about 6 days to about 11 days, from about 6 days to about 12 days, from about 6 days to about 13 days, about 6 days to about 14 days, about 6 days to about 15 days, about 7 days to about 8 days, about 7 days to about 9 days, about 7 days to about 10 days, from about 7 days to about 11 days, from about 7 days to about 12 days, from about 7 days to about 13 days, from about 7 days to about 14 days, from about 7 days to about 15 days, from about 8 days to about 9 days, about 8 days to about 10 days, about 8 days to about 11 days, about 8 days to about 12 days, about 8 days to about 13 days, about 8 days to about 14 days , from about 8 days to about 15 days, from about 9 days to about 10 days, from about 9 days to about 11 days, from about 9 days to about 12 days, from about 9 days to about 13 days, from about 9 days to about 14 days, from about 9 days to about 15 days, from about 10 days to about 11 days, from about 10 days to about 12 days, from about 10 days to about 13 days, from about 10 days to about 14 days, from about 10 days to about 15 days, from about 11 days to about 12 days, from about 11 days to about 13 days, from about 11 days to about 14 days, from about 11 days to about 15 days, from about 12 days to about 13 days, about 12 days to about 14 days, about 12 days to about 15 days, about 13 days to about 14 days, about 13 days to about 15 days, or about 14 days to about 15 days.

In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, about 1 week, about 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6 weeks, 7 weeks, 8 weeks, 9 weeks, 10 weeks, 11 weeks, 12 weeks, 13 weeks, 14 weeks or 15 weeks. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, at least 1 week, at least 2 weeks, at least 3 weeks, at least 4 weeks, at least 5 weeks , at least 6 weeks, at least 7 weeks, at least 8 weeks, at least 9 weeks, at least 10 weeks, at least 11 weeks, at least 12 weeks, at least 13 weeks, according to at least 14 weeks or at least 15 weeks. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, no more than 1 week, no more than 2 weeks, no more than 3 weeks, no more than 4 weeks, no more than 5 weeks, no more than 6 weeks , no more than 7 weeks, no more than 8 weeks, no more than 9 weeks, no more than 10 weeks, no more than 11 weeks, no more than 12 weeks, no more than 13 weeks, no more than 14 weeks or no more than 15 weeks.

In aspects according to this embodiment, the composition described in the present invention is stable for, for example, from about 1 week to about 2 weeks, from about 1 week to about 3 weeks, from about 1 week to about 4 weeks, from about 1 weeks to about 5 weeks, about 1 week to about 6 weeks, about 1 week to about 7 weeks, about 1 week to about 8 weeks, about 1 week to about 9 weeks, about 1 week to about 10 weeks , from about 1 week to about 11 weeks, from about 1 week to about 12 weeks, from about 1 week to about 13 weeks, from about 1 week to about 14 weeks, from about 1 week to about 15 weeks, from about 2 weeks to about 3 weeks, from about 2 weeks to about 4 weeks, from about 2 weeks to about 5 weeks, from about 2 weeks to about 6 weeks, from about 2 weeks to about 7 weeks, from about 2 weeks to about 8 weeks, from about 2 weeks to about 9 weeks, from about 2 weeks to about 10 weeks, from about 2 weeks to about 11 weeks, from about 2 weeks to about 12

- 41 043933 weeks, from about 2 weeks to about 13 weeks, from about 2 weeks to about 14 weeks, from about 2 weeks to about 15 weeks, from about 3 weeks to about 4 weeks, from about 3 weeks to about 5 weeks, from about 3 weeks to about 6 weeks, from about 3 weeks to about 7 weeks, from about 3 weeks to about 8 weeks, from about 3 weeks to about 9 weeks, from about 3 weeks to about 10 weeks, from about 3 weeks to about 11 weeks, from about 3 weeks to about 12 weeks, from about 3 weeks to about 13 weeks, from about 3 weeks to about 14 weeks, from about 3 weeks to about 15 weeks, from about 4 weeks to about 5 weeks, from about 4 weeks to about 6 weeks, about 4 weeks to about 7 weeks, about 4 weeks to about 8 weeks, about 4 weeks to about 9 weeks, about 4 weeks to about 10 weeks, about 4 weeks to about 11 weeks, from about 4 weeks to about 12 weeks, from about 4 weeks to about 13 weeks, from about 4 weeks to about 14 weeks, from about 4 weeks to about 15 weeks, from about 5 weeks to about 6 weeks, from about 5 weeks to about 7 weeks, about 5 weeks to about 8 weeks, about 5 weeks to about 9 weeks, about 5 weeks to about 10 weeks, about 5 weeks to about 11 weeks, about 5 weeks to about 12 weeks, from about 5 weeks to about 13 weeks, from about 5 weeks to about 14 weeks, from about 5 weeks to about 15 weeks, from about 6 weeks to about 7 weeks, from about 6 weeks to about 8 weeks, from about 6 weeks to about 9 weeks, about 6 weeks to about 10 weeks, about 6 weeks to about 11 weeks, about 6 weeks to about 12 weeks, about 6 weeks to about 13 weeks, about 6 weeks to about 14 weeks , from about 6 weeks to about 15 weeks, from about 7 weeks to about 8 weeks, from about 7 weeks to about 9 weeks, from about 7 weeks to about 10 weeks, from about 7 weeks to about 11 weeks, from about 7 weeks to about 12 weeks, from about 7 weeks to about 13 weeks, from about 7 weeks to about 14 weeks, from about 7 weeks to about 15 weeks, from about 8 weeks to about 9 weeks, from about 8 weeks to about 10 weeks, from about 8 weeks to about 11 weeks, from about 8 weeks to about 12 weeks, from about 8 weeks to about 13 weeks, from about 8 weeks to about 14 weeks, from about 8 weeks to about 15 weeks, from about 9 weeks to about 10 weeks, from about 9 weeks to about 11 weeks, from about 9 weeks to about 12 weeks, from about 9 weeks to about 13 weeks, from about 9 weeks to about 14 weeks, from about 9 weeks to about 15 weeks, from about 10 weeks to about 11 weeks, about 10 weeks to about 12 weeks, about 10 weeks to about 13 weeks, about 10 weeks to about 14 weeks, about 10 weeks to about 15 weeks, about 11 weeks to about 12 weeks, from about 11 weeks to about 13 weeks, from about 11 weeks to about 14 weeks, from about 11 weeks to about 15 weeks, from about 12 weeks to about 13 weeks, from about 12 weeks to about 14 weeks, from about 12 weeks to about 15 weeks, about 13 weeks to about 14 weeks, about 13 weeks to about 15 weeks, or about 14 weeks to about 15 weeks.

In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, about 1 month, about 2 months, 3 months, 4 months, 5 months, 6 months, 7 months, 8 months, 9 months, 10 months, 11 months, 12 months, 13 months, 14 months, 15 months, 16 months, 17 months or 18 months. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, at least 1 month, at least 2 months, at least 3 months, at least 4 months, at least 5 months , at least 6 months, at least 7 months, at least 8 months, at least 9 months, at least 10 months, at least 11 months, at least 12 months, at least 13 months, according to at least 14 months, at least 15 months, at least 16 months, at least 17 months or at least 18 months. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, no more than 1 month, no more than 2 months, no more than 3 months, no more than 4 months, no more than 5 months, no more than 6 months , no more than 7 months, no more than 8 months, no more than 9 months, no more than 10 months, no more than 11 months, no more than 12 months, no more than 13 months, no more than 14 months, no more than 15 months, no more than 16 months , no more than 17 months or no more than 18 months.

In aspects according to this embodiment, the composition described in the present invention is stable for, for example, from about 1 month to about 2 months, from about 1 month to about 3 months, from about 1 month to about 4 months, from about 1 month to about 5 months, from about 1 month to about 6 months, from about 1 month to about 7 months, from about 1 month to about 8 months, from about 1 month to about 9 months, from about 1 month to about 10 months , from about 1 month to about 11 months, from about 1 month to about 12 months, from about 1 month to about 13 months, from about 1 month to about 14 months, from about 1 month to about 15 months, from about 1 month up to about 16 months, from about 1 month to about 17 months, from about 1 month to

- 42 043933 approximately 18 months, from approximately 2 months to approximately 3 months, from approximately 2 months to approximately 4 months, from approximately 2 months to approximately 5 months, from approximately 2 months to approximately 6 months, from approximately 2 months to approximately 7 months, from about 2 months to about 8 months, from about 2 months to about 9 months, from about 2 months to about 10 months, from about 2 months to about 11 months, from about 2 months to about 12 months, from about 2 months to about 13 months, about 2 months to about 14 months, about 2 months to about 15 months, about 2 months to about 16 months, about 2 months to about 17 months, about 2 months to about 18 months , from about 3 months to about 4 months, from about 3 months to about 5 months, from about 3 months to about 6 months, from about 3 months to about 7 months, from about 3 months to about 8 months, from about 3 months up to about 9 months, from about 3 months to about 10 months, from about 3 months to about 11 months, from about 3 months to about 12 months, from about 3 months to about 13 months, from about 3 months to about 14 months, from about 3 months to about 15 months, from about 3 months to about 16 months, from about 3 months to about 17 months, from about 3 months to about 18 months, from about 4 months to about 5 months, from about 4 months to about 6 months, from about 4 months to about 7 months, from about 4 months to about 8 months, from about 4 months to about 9 months, from about 4 months to about 10 months, from about 4 months to about 11 months, from about 4 months to about 12 months, about 4 months to about 13 months, about 4 months to about 14 months, about 4 months to about 15 months, about 4 months to about 16 months, about 4 months to about 17 months, from about 4 months to about 18 months, from about 5 months to about 6 months, from about 5 months to about 7 months, from about 5 months to about 8 months, from about 5 months to about 9 months, from about 5 months to about 10 months, about 5 months to about 11 months, about 5 months to about 12 months, about 5 months to about 13 months, about 5 months to about 14 months, about 5 months to about 15 months, from about 5 months to about 16 months, from about 5 months to about 17 months, from about 5 months to about 18 months, from about 6 months to about 7 months, from about 6 months to about 8 months, from about 6 months months to about 9 months, about 6 months to about 10 months, about 6 months to about 11 months, about 6 months to about 12 months, about 6 months to about 13 months, about 6 months to about 14 months , from about 6 months to about 15 months, from about 6 months to about 16 months, from about 6 months to about 17 months, from about 6 months to about 18 months, from about 7 months to about 8 months, from about 7 months up to about 9 months, from about 7 months to about 10 months, from about 7 months to about 11 months, from about 7 months to about 12 months, from about 7 months to about 13 months, from about 7 months to about 14 months, from about 7 months to about 15 months, from about 7 months to about 16 months, from about 7 months to about 17 months, from about 7 months to about 18 months, from about 8 months to about 9 months, from about 8 months to about 10 months, from about 8 months to about 11 months, from about 8 months to about 12 months, from about 8 months to about 13 months, from about 8 months to about 14 months, from about 8 months to about 15 months, from about 8 months to about 16 months, about 8 months to about 17 months, about 8 months to about 18 months, about 9 months to about 10 months, about 9 months to about 11 months, about 9 months to about 12 months, from about 9 months to about 13 months, from about 9 months to about 14 months, from about 9 months to about 15 months, from about 9 months to about 16 months, from about 9 months to about 17 months, from about 9 months to about 18 months, about 10 months to about 11 months, about 10 months to about 12 months, about 10 months to about 13 months, about 10 months to about 14 months, about 10 months to about 15 months, from about 10 months to about 16 months, from about 10 months to about 17 months, from about 10 months to about 18 months, from about 11 months to about 12 months, from about 11 months to about 13 months, from about 11 months to about 14 months, about 11 months to about 15 months, about 11 months to about 16 months, about 11 months to about 17 months, about 1 month to about 18 months, about 12 months to about 13 months , from about 12 months to about 14 months, from about 12 months to about 15 months, from about 12 months to about 16 months, from about 12 months to about 17 months, from about 12 months to about 18 months, from about 13 months to about 14 months, from about 13 months to about 15 months, from about 13 months to about 16 months, from about 13 months to about 17 months, from about 13 months to about 18 months, from about 14 months to about 15 months, from about 14 months to about 16 months, from about 14 months to about 17 months, from about 14 months to about 18 months, from about 15 months to about 16 months, from about 15 months to about 43 043933 but 17 months, from about 15 months to about 18 months, about 16 months to about 17 months, about 16 months to about 18 months, or about 17 months to about 18 months.

In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, about 1 year, about 2 years, about 3 years, about 4 years, or about 5 years. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, at least 1 year, at least 2 years, at least 3 years, at least 4 years, or at least 5 years . In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, no more than 1 year, no more than 2 years, no more than 3 years, no more than 4 years, or no more than 5 years. In other aspects, according to this embodiment, the composition described in the present invention is stable for, for example, from about 1 year to about 2 years, from about 1 year to about 3 years, from about 1 year to about 4 years, from about 1 year to about 5 years, from about 2 years to about 3 years, from about 2 years to about 4 years, from about 2 years to about 5 years, from about 3 years to about 4 years, from about 3 years to about 5 years years or from about 4 years to about 5 years.

The composition described in the present invention can be obtained in any form that allows the composition described in the present invention to be applied in such a way as to achieve the desired beneficial effect. In one embodiment, the composition described in the present invention can be obtained, for example, in the form of a single-phase composition or a two-phase composition containing a medium phase and a dispersed phase. In another embodiment, the composition described in the present invention can be obtained, for example, in the form of a liquid composition, colloidal composition, semi-solid composition or solid composition. In another embodiment, the composition described in the present invention can be obtained, for example, in the form of an aerosol of liquid particles, foam, emulsion, gel, sol or solid sol. In another embodiment, the composition described in the present invention can be obtained, for example, in the form of a spray, aerosol of liquid particles, soap or suspension.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3-trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 1000 ppm of hypochlorous acid or free active chlorine and from 250 ppm to 1500 ppm of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains 100 ppm to 1000 ppm of hypochlorous acid or free active chlorine and from 250 ppm to 1500 ppm of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 250 ppm to 1500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-( 3trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 1000 ppm of hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 1000 ppm of hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-( 3trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm of hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds . In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm hypochlorous acid or free active chlorine and from 500 ppm to 1500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-( 3trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm of hypochlorous acid or free active chlorine and from 500 ppm to 1200 ppm of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm of hypochlorous acid or free active chlorine and from 500 ppm to 1200 ppm of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 800 ppm hypochlorous acid or free active chlorine and from 500 ppm to 1200 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3 -trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 170 ppm to 370 ppm hypochlorous acid or free active chlorine and from 100 ppm to 200 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 190 ppm to 350 ppm hypochlorous acid or free active chlorine and from 120 ppm to 280 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 210 ppm to 330 ppm hypochlorous acid or free active chlorine and from 140 ppm to 260 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 230 ppm to 310 ppm hypochlorous acid or free active chlorine and from 160 ppm to 240 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 250 ppm to 290 ppm hypochlorous acid or free active chlorine and from 180 ppm to 220 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 273 ppm hypochlorous acid or free active chlorine and 200 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 170 ppm to 370 ppm hypochlorous acid or free active chlorine and from 200 ppm to 400 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 190 ppm to 350 ppm hypochlorous acid or free active chlorine and from 220 ppm to 380 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 210 ppm to 330 ppm hypochlorous acid or free active chlorine and from 240 ppm to 360 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 230 ppm to 310 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 250 ppm to 290 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 273 ppm hypochlorous acid or free active chlorine and 300 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 400 ppm to 600 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 420 ppm to 580 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 440 ppm to 560 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 460 ppm to 540 ppm dimethyl

- 45 043933 loctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 480 ppm to 520 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In another aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 250 ppm to 350 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 270 ppm to 330 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 290 ppm to 310 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 300 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 200 ppm to 300 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 210 ppm to 290 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 220 ppm to 280 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 230 ppm to 270 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 240 ppm to 260 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 250 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 150 ppm to 250 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 160 ppm to 240 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 170 ppm to 230 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 180 ppm to 220 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 190 ppm to 210 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or

- 46 043933 free active chlorine and 200 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 100 ppm to 200 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 110 ppm to 190 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 120 ppm to 180 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 130 ppm to 170 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 140 ppm to 160 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 150 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 125 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 50 ppm to 150 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 60 ppm to 140 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 70 ppm to 130 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 80 ppm to 120 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 90 ppm to 110 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 100 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 125 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 100 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 10 ppm to 90 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 20 ppm to 80 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 30 ppm to 70 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 40 ppm to 60 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 50 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 50 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention

- 47 043933 contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 5 ppm to 45 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 10 ppm to 40 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 15 ppm to 35 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 20 ppm to 30 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 25 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 400 ppm to 600 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 420 ppm to 580 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 440 ppm to 560 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 460 ppm to 540 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 480 ppm to 520 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 500 ppm to 700 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 520 ppm to 680 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 540 ppm to 660 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 560 ppm to 640 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 580 ppm to 620 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 600 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 500 ppm to 700 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 520 ppm to 680 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 540 ppm to 660 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 560 ppm to 640 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to a specified embodiment of the component

- 48 043933 The item described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 580 ppm to 620 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 600 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 500 ppm to 700 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 520 ppm to 680 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 540 ppm to 660 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 560 ppm to 640 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 580 ppm to 620 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 600 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 600 ppm to 800 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 620 ppm to 780 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 640 ppm to 760 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 660 ppm to 740 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 680 ppm to 720 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 700 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 600 ppm to 800 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 620 ppm to 780 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 640 ppm to 760 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 660 ppm to 740 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 680 ppm to 720 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 700 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to a specified embodiment, the composition described in the present

- 49 043933 of our invention, contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 600 ppm to 800 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 620 ppm to 780 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 640 ppm to 760 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 660 ppm to 740 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 680 ppm to 720 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 700 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 700 ppm to 900 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 720 ppm to 880 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 740 ppm to 860 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 760 ppm to 840 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 780 ppm to 820 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 800 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 700 ppm to 900 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 720 ppm to 880 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 740 ppm to 860 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 760 ppm to 840 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 780 ppm to 820 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 800 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 700 ppm to 900 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 720 ppm to 880 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 740 ppm to

- 50 043933

860 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 760 ppm to 840 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 780 ppm to 820 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 800 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 800 ppm to 1000 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 820 ppm to 980 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 840 ppm to 960 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 860 ppm to 940 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 880 ppm to 920 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 900 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 800 ppm to 1000 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 820 ppm to 980 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 840 ppm to 960 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 860 ppm to 940 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 880 ppm to 920 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 900 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 800 ppm to 1000 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 820 ppm to 980 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 840 ppm to 960 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 860 ppm to 940 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 880 ppm to 920 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 900 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 900 ppm to 1100 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 920 ppm to 1080 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 940 ppm to 1060 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 960 ppm to 1040 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 980 ppm to 1020 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1000 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 900 ppm to 1100 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 920 ppm to 1080 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 940 ppm to 1060 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 960 ppm to 1040 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 980 ppm to 1020 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1000 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 900 ppm to 1100 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 920 ppm to 1080 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 940 ppm to 1060 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 960 ppm to 1040 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 980 ppm to 1020 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1000 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active

- 52 043933 chlorine and from 1000 ppm to 1200 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 1020 ppm to 1180 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 1040 ppm to 1160 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 1060 ppm to 1140 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 1080 ppm to 1120 ppm quaternary compound or organosilicon quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1100 ppm quaternary compound or organosilicon quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 1000 ppm to 1200 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 1020 ppm to 1180 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 1040 ppm to 1160 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 1060 ppm to 1140 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 1080 ppm to 1120 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1100 ppm dialkyl quaternary compound or organosilicon dialkyl quaternary compound.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 1000 ppm to 1200 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 1020 ppm to 1180 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 1040 ppm to 1160 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 1060 ppm to 1140 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 1080 ppm to 1120 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 1100 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride.

In one embodiment, the composition described in the present invention contains one or more alcohols and one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains one or more alcohols and one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains one or more alcohols and dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetrad

- 53 043933 cyldimethyl-(3-trimethoxysilyl)propylammonium chloride.

In one embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 1% to 15% of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 1% to 15% of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 1% to 15% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3- trimethoxysilyl)propylammonium chloride.

In one embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 1% to 10% of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 1% to 10% of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 1% to 10% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3- trimethoxysilyl)propylammonium chloride.

In one embodiment, the composition described in the present invention contains isopropanol, methanol and one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains isopropanol, methanol and one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains isopropanol, methanol and dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3-trimethoxysilyl)propylammonium chloride.

In one embodiment, the composition described in the present invention contains from 10% to 90% a mixture of isopropanol and methanol and from 1% to 15% of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% a mixture of isopropanol and methanol and from 1% to 15% of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% a mixture of isopropanol and methanol and from 1% to 15% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3- trimethoxysilyl)propylammonium chloride.

In one embodiment, the composition described in the present invention contains from 25% to 75% a mixture of isopropanol and methanol and from 1% to 10% of one or more quaternary compounds or organosilicon quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% a mixture of isopropanol and methanol and from 1% to 10% of one or more dialkyl quaternary compounds or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% a mixture of isopropanol and methanol and from 1% to 10% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3- trimethoxysilyl)propylammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 30% to 70% isopropanol, from 0.1% to 4.0% methanol and from 1% to 9% dimethyloctadecyl[3-(trimethoxysilyl)propyl ]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 35% to 65% isopropanol, from 0.5% to 3.5% methanol and from 2% to 8% dimethyloctadecyl[3-(trimethoxysilyl)propyl ]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 40% to 60% isopropanol, from 1.0% to 3.0% methanol and from 3% to 7% dimethyloctadecyl[3-(trimethoxysilyl)propyl ]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 45% to 55% isopropanol, from 1.5% to 2.5% methanol and from 4% to 6% dimethyloctadecyl[3(trimethoxysilyl)propyl] ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 50% isopropanol, 2% methanol and 5% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 30% to 70% isopropanol, from 2% to 10% methanol and from 1% to 9% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 35% to 65% iso

- 54 043933 propanol, from 3% to 9% methanol and from 2% to 8% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 40% to 60% isopropanol, from 4% to 8% methanol and from 3% to 7% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 45% to 55% isopropanol, from 5% to 7% methanol and from 4% to 6% dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 50% isopropanol, 6% methanol and 5% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 94% to 99% isopropanol, from 0.1% to 2.0% methanol and from 0.1% to 2.0% dimethyloctadecyl[3- (trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 95% to 99% isopropanol, from 0.25% to 1.75% methanol and from 0.25% to 1.75% dimethyloctadecyl[3( trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 96% to 99% isopropanol, from 0.5% to 1.5% methanol and from 0.5% to 1.5% dimethyloctadecyl[3- (trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 97% to 99% isopropanol, from 0.75% to 1.25% methanol and from 0.75% to 1.25% dimethyloctadecyl[3- (trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 98% isopropanol, 1% methanol and 1% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one aspect, according to this embodiment, the composition described in the present invention contains from 70% to 99% isopropanol, from 1% to 10% methanol and from 1% to 10% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 75% to 97% isopropanol, from 4% to 9% methanol and from 2% to 8% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 80% to 95% isopropanol, from 5% to 8% methanol and from 3% to 7% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 85% to 90% isopropanol, from 6% to 7% methanol and from 4% to 6% dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 88.4% isopropanol, 6.6% methanol and 5% dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride.

In one embodiment, the composition described in the present invention contains isopropanol and didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 30% to 70% isopropanol and from 1.0% to 20.0% didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 35% to 65% isopropanol and from 2.5% to 17.5% didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 40% to 60% isopropanol and from 5.0% to 15.0% didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 45% to 55% isopropanol and from 7.5% to 12.5% didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 50% isopropanol and 10% didodecyldimethylammonium chloride.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 200 ppm to 400 ppm didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 220 ppm to 380 ppm didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 240 ppm to 360 ppm didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm didodecyldimethylammonium chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm didodecyldimethylammonium chloride. In one of

- 55 043933 aspects according to the specified embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 300 ppm didodecyldimethylammonium chloride.

In one embodiment, the composition described in the present invention contains one or more alcohols and one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains one or more alcohols and one or more compounds containing a biguanide moiety or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains one or more alcohols and polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 0.1% to 5% of one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 0.1% to 5% of one or more compounds containing a biguanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% of one or more alcohols and from 0.1% to 5% polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 0.5% to 2.5% of one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 0.5% to 2.5% of one or more compounds containing a biguanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% of one or more alcohols and from 0.5% to 2.5% polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains isopropanol and one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains isopropanol and one or more compounds containing a biguanide moiety or organosilicon dialkyl quaternary compounds. In one aspect, according to this embodiment, the composition described in the present invention contains isopropanol and polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains from 10% to 90% isopropanol and from 0.1% to 5% of one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% isopropanol and from 0.1% to 5% of one or more compounds containing a biguanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 10% to 90% isopropanol and from 0.1% to 5% polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains from 25% to 75% isopropanol and from 0.5% to 2.5% of one or more compounds containing a guanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% isopropanol and from 0.5% to 2.5% of one or more compounds containing a biguanide moiety. In one aspect, according to this embodiment, the composition described in the present invention contains from 25% to 75% isopropanol and from 0.5% to 2.5% polyhexamethylene biguanide.

In one aspect, according to this embodiment, the composition described in the present invention contains from 30% to 70% isopropanol and from 0.1% to 2.0% polyhexamethylene biguanide. In one aspect, according to this embodiment, the composition described in the present invention contains from 35% to 65% isopropanol and from 0.25% to 1.75% polyhexamethylene biguanide. In one aspect, according to this embodiment, the composition described in the present invention contains from 40% to 60% isopropanol and from 0.5% to 1.5% polyhexamethylene biguanide. In one aspect, according to this embodiment, the composition described in the present invention contains from 45% to 55% isopropanol and from 0.75% to 1.25% polyhexamethylene biguanide. In one aspect, according to this embodiment, the composition described in the present invention contains 50% isopropanol and 1% polyhexamethylene biguanide.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and metal particles and/or metal salts. In one embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm metal particles and/or metal salts.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and silver nitrate. In aspects according to the specified embodiment, the composition described in the present invention contains from 200 ppm to

- 56 043933

1000 ppm hypochlorous acid or free active chlorine and 50 ppm to 500 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 300 ppm to 900 ppm hypochlorous acid or free active chlorine and from 100 ppm to 400 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 800 ppm hypochlorous acid or free active chlorine and from 150 ppm to 350 ppm silver nitrate.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine and from 200 ppm to 400 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine and from 220 ppm to 380 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine and from 240 ppm to 360 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm silver nitrate. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm silver nitrate. In one embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine and 300 ppm silver nitrate.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine, silver nitrate and titanium dioxide particles. In aspects according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine, from 50 ppm to 500 ppm silver nitrate, and from 10 ppm to 400 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 300 ppm to 900 ppm hypochlorous acid or free active chlorine, from 100 ppm to 400 ppm silver nitrate and from 25 ppm to 350 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 800 ppm hypochlorous acid or free active chlorine, from 150 ppm to 350 ppm silver nitrate and from 50 ppm to 250 ppm titanium dioxide particles.

In aspects according to this embodiment, the composition described in the present invention contains from 1 ppm to 200 ppm hypochlorous acid or free active chlorine, from 50 ppm to 500 ppm silver nitrate, and from 10 ppm to 400 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 175 ppm hypochlorous acid or free active chlorine, from 100 ppm to 400 ppm silver nitrate and from 25 ppm to 350 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 150 ppm hypochlorous acid or free active chlorine, from 150 ppm to 350 ppm silver nitrate and from 50 ppm to 250 ppm titanium dioxide particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine, from 100 ppm to 300 ppm silver nitrate and from 50 ppm to 150 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine, from 120 ppm to 280 ppm silver nitrate and from 60 ppm to 140 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine, from 140 ppm to 260 ppm silver nitrate and from 70 ppm to 130 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine, from 160 ppm to 240 ppm silver nitrate and from 80 ppm to 120 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine, from 180 ppm to 220 ppm silver nitrate and from 90 ppm to 110 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine, 200 ppm silver nitrate and 100 ppm titanium dioxide particles.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine, a quaternary compound or an organosilicon quaternary compound, and metal particles and/or metal salts. In aspects according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine, a dialkyl quaternary compound or an organosilicon dialkyl quaternary compound, and metal particles and/or metal salts. In aspects according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine, dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride or tetradecyldimethyl-(3-trimethoxysilyl)propylammonium chloride, silver nitrate and titanium dioxide particles.

In aspects according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine, from 200 ppm to 1000 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 50 ppm to 500 ppm silver nitrate and from 10 ppm to 400 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 300 ppm to 900 ppm hypochlorous acid or free active chlorine, from 300 ppm to 900 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 100 ppm up to 400 ppm silver nitrate and from 25 ppm to 350 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 800 ppm hypochlorous acid or free active chlorine, from 400 ppm to 800 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 150 ppm to 350 ppm silver nitrate and 50 ppm to 250 ppm titanium dioxide particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 180 ppm to 380 ppm hypochlorous acid or free active chlorine, from 200 ppm to 400 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 100 ppm up to 300 ppm silver nitrate and from 50 ppm to 150 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 360 ppm hypochlorous acid or free active chlorine, from 220 ppm to 380 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 120 ppm up to 280 ppm silver nitrate and from 60 ppm to 140 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 220 ppm to 340 ppm hypochlorous acid or free active chlorine, from 240 ppm to 360 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 140 ppm to 260 ppm silver nitrate and 70 ppm to 130 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 240 ppm to 320 ppm hypochlorous acid or free active chlorine, from 260 ppm to 340 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 160 ppm to 240 ppm silver nitrate and 80 ppm to 120 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 260 ppm to 300 ppm hypochlorous acid or free active chlorine, from 280 ppm to 320 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 180 ppm to 220 ppm silver nitrate and 90 ppm to 110 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains 281 ppm hypochlorous acid or free active chlorine, 300 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, 200 ppm silver nitrate and 100 ppm titanium dioxide particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 430 ppm to 630 ppm hypochlorous acid or free active chlorine, from 400 ppm to 600 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 200 ppm up to 400 ppm silver nitrate and from 50 ppm to 150 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 450 ppm to 610 ppm hypochlorous acid or free active chlorine, from 420 ppm to 580 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, from 220 ppm up to 380 ppm silver nitrate and from 60 ppm to 140 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 470 ppm to 590 ppm hypochlorous acid or free active chlorine, from 440 ppm to 560 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 240 ppm to 360 ppm silver nitrate and 70 ppm to 130 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 490 ppm to 570 ppm hypochlorous acid or free active chlorine, from 460 ppm to 540 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 260 ppm to 340 ppm silver nitrate and 80 ppm to 120 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains from 510 ppm to 550 ppm hypochlorous acid or free active chlorine, from 480 ppm to 520 ppm dimethyloctadecyl[3(trimethoxysilyl)propyl]ammonium chloride, from 280 ppm to 320 ppm silver nitrate and 90 ppm to 110 ppm titanium dioxide particles. In one aspect, according to this embodiment, the composition described in the present invention contains 530 ppm hypochlorous acid or free active chlorine, 500 ppm dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, 300 ppm

- 58 043933 silver nitrate and 100 ppm titanium dioxide particles.

In one embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and a copper particle, a zinc particle, an iron particle, or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and a copper oxide particle, a zinc oxide particle, an iron oxide particle, or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and a particle of mixed oxide of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper particles, from 50 ppm to 500 ppm zinc particles, 50 ppm to 500 ppm iron particles or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper oxide particles, from 50 ppm to 500 ppm zinc oxide particles, from 50 ppm to 500 ppm iron oxide particles or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper particles, from 50 ppm to 500 ppm zinc particles, from 50 ppm up to 500 ppm iron particles or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper oxide particles, from 50 ppm to 500 ppm zinc oxide particles, from 50 ppm to 500 ppm iron oxide particles or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 50 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 5 ppm to 45 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 10 ppm to 40 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 15 ppm to 35 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 20 ppm to 30 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 25 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 1 ppm to 100 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 10 ppm to 90 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 20 ppm to 80 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 30 ppm to 70 ppm mixed oxide particles of copper, zinc and iron. In one

- 59 043933 of aspects according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 40 ppm to 60 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 50 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 50 ppm to 150 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 60 ppm to 140 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 70 ppm to 130 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 80 ppm to 120 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 90 ppm to 110 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 100 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 100 ppm to 200 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 110 ppm to 190 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 120 ppm to 180 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 130 ppm to 170 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 140 ppm to 160 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 150 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 150 ppm to 250 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 160 ppm to 240 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 170 ppm to 230 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 180 ppm to 220 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 190 ppm to 210 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 200 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 200 ppm to 300 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 210 ppm to 290 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm

- 60 043933 hypochlorous acid or free active chlorine and from 220 ppm to 280 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 230 ppm to 270 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 240 ppm to 260 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 250 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine and from 250 ppm to 350 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine and from 270 ppm to 330 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine and from 290 ppm to 310 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine and 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 1 ppm to 400 ppm mixed oxide particles of copper, zinc and iron. In another aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 25 ppm to 300 ppm mixed oxide particles of copper, zinc and iron.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 1 ppm to 50 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 5 ppm to 45 ppm mixture particles

- 61 043933 oxide of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 10 ppm to 40 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 15 ppm to 35 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 20 ppm to 30 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 25 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 1 ppm to 100 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 10 ppm to 90 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 20 ppm to 80 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 30 ppm to 70 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 40 ppm to 60 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 50 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 150 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 60 ppm to 140 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 70 ppm to 130 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 80 ppm to 120 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 90 ppm to 110 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 100 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 100 ppm to 200 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 110 ppm to 190 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 120 ppm to 180 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 130 ppm to 170 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 140 ppm to 160 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 150 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 150 ppm to 250 ppm mixed oxide particles of copper, zinc and iron. In one aspect

- 62 043933 According to the specified embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 160 ppm to 240 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 170 ppm to 230 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 180 ppm to 220 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 190 ppm to 210 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 200 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 200 ppm to 300 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 210 ppm to 290 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 220 ppm to 280 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 230 ppm to 270 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 240 ppm to 260 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 250 ppm mixed oxide copper, zinc and iron particles.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine and from 250 ppm to 350 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine and from 260 ppm to 340 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine and from 270 ppm to 330 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine and from 280 ppm to 320 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine and from 290 ppm to 310 ppm mixed oxide particles of copper, zinc and iron. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine and 300 ppm mixed oxide copper, zinc and iron particles.

In aspects according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and a copper salt, a zinc salt, an iron salt, or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and a copper salt, a zinc salt and an iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and copper chloride, zinc chloride, ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains hypochlorous acid or free active chlorine and copper chloride, zinc chloride and ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from

- 63 043933 ppm to 500 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 200 ppm to 1000 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 50 ppm to 500 ppm hypochlorous acid or free active chlorine and from 10 ppm to 250 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 50 ppm to 500 ppm hypochlorous acid or free active chlorine and from 10 ppm to 250 ppm copper salt, from 10 ppm to 250 ppm zinc salt, from 10 ppm up to 250 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 50 ppm to 500 ppm hypochlorous acid or free active chlorine and from 10 ppm to 250 ppm copper salt, from 10 ppm to 250 ppm zinc salt and from 10 ppm up to 250 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 50 ppm to 500 ppm hypochlorous acid or free active chlorine and from 10 ppm to 250 ppm copper chloride, from 10 ppm to 250 ppm zinc chloride, from 10 ppm up to 250 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 50 ppm to 500 ppm hypochlorous acid or free active chlorine and from 10 ppm to 250 ppm copper chloride, from 10 ppm to 250 ppm zinc chloride and from 10 ppm up to 250 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 75 ppm to 400 ppm hypochlorous acid or free active chlorine and from 20 ppm to 200 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 75 ppm to 400 ppm hypochlorous acid or free active chlorine and from 20 ppm to 200 ppm copper salt, from 20 ppm to 200 ppm zinc salt, from 20 ppm up to 200 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 75 ppm to 400 ppm hypochlorous acid or free active chlorine and from 20 ppm to 200 ppm copper salt, from 20 ppm to 200 ppm zinc salt and from 20 ppm up to 200 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 75 ppm to 400 ppm hypochlorous acid or free active chlorine and from 20 ppm to 200 ppm copper chloride, from 20 ppm to 200 ppm zinc chloride, from 20 ppm up to 200 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 75 ppm to 400 ppm hypochlorous acid or free active chlorine and from 20 ppm to 200 ppm copper chloride, from 20 ppm to 200 ppm zinc chloride and from 20 ppm up to 200 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 100 ppm to 350 ppm hypochlorous acid or free active chlorine and from 40 ppm to 140 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 350 ppm hypochlorous acid or free active chlorine and from 40 ppm to 140 ppm copper salt, from 40 ppm to 140 ppm zinc salt, from 40 ppm up to 140 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 350 ppm hypochlorous acid or free active chlorine and from 40 ppm to 140 ppm copper salt, from 40 ppm to 140 ppm zinc salt and from 40 ppm up to 140 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 350 ppm hypochlorous acid or free active chlorine and from 40 ppm to 140 ppm copper chloride, from 40 ppm to 140 ppm zinc chloride, from 40 ppm up to 140 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 100 ppm to 350 ppm hypochlorous acid or free active chlorine and from 40 ppm to 140 ppm copper chloride, from 40 ppm to 140 ppm zinc chloride and from 40 ppm up to 140 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to a specified embodiment of the composition

- 64 043933 tion described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from 50 ppm to 500 ppm iron salt or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 200 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from 50 ppm up to 500 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 150 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from 50 ppm up to 500 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 100 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from 50 ppm up to 500 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 75 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one embodiment, the composition described in the present invention contains:

- 65 043933 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm one or more metal salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt, from 50 ppm up to 500 ppm iron salts or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper salt, from 50 ppm to 500 ppm zinc salt and from 50 ppm up to 500 ppm iron salt. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride, from 50 ppm up to 500 ppm ferric chloride or any combination thereof. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 50 ppm hypochlorous acid or free active chlorine and from 50 ppm to 500 ppm copper chloride, from 50 ppm to 500 ppm zinc chloride and from 50 ppm up to 500 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 50 ppm to 150 ppm copper salt, from 50 ppm to 150 ppm zinc salt and from 50 ppm up to 150 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 60 ppm to 140 ppm copper salt, from 60 ppm to 140 ppm zinc salt and from 60 ppm up to 140 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 70 ppm to 130 ppm copper salt, from 70 ppm to 130 ppm zinc salt and from 70 ppm up to 130 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 80 ppm to 120 ppm copper salt, from 80 ppm to 120 ppm zinc salt and from 80 ppm up to 120 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 90 ppm to 110 ppm copper salt, from 90 ppm to 110 ppm zinc salt and from 90 ppm up to 110 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 100 ppm copper salt, 100 ppm zinc salt and 100 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 50 ppm to 150 ppm zinc chloride, from 50 ppm to 150 ppm zinc chloride and from 50 ppm up to 150 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 60 ppm to 140 ppm zinc chloride, from 60 ppm to 140 ppm zinc chloride and from 60 ppm up to 140 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 70 ppm to 130 ppm zinc chloride, from 70 ppm to 130 ppm zinc chloride and from 70 ppm up to 130 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 80 ppm to 120 ppm zinc chloride, from 80 ppm to 120 ppm zinc chloride and from 80 ppm up to 120 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 90 ppm to 110 ppm zinc chloride, from 90 ppm to 110 ppm zinc chloride and from 90 ppm up to 110 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 100 ppm zinc chloride, 100 ppm zinc chloride and 100 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 100 ppm to 200 ppm copper salt, from 100 ppm to 200 ppm zinc salt and from 100 ppm up to 200 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 110 ppm to 190 ppm copper salt, from 110 ppm to 190 ppm zinc salt and from 110 ppm up to 190 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 120 ppm to 180 ppm copper salt, from 120 ppm to 180 ppm zinc salt and from 120 ppm

- 66 043933 up to 180 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 130 ppm to 170 ppm copper salt, from 130 ppm to 170 ppm zinc salt and from 130 ppm up to 170 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 140 ppm to 160 ppm copper salt, from 140 ppm to 160 ppm zinc salt and from 140 ppm up to 160 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 150 ppm copper salt, 150 ppm zinc salt and 150 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 100 ppm to 200 ppm zinc chloride, from 100 ppm to 200 ppm zinc chloride and from 100 ppm up to 200 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 110 ppm to 190 ppm zinc chloride, from 110 ppm to 190 ppm zinc chloride and from 110 ppm up to 190 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 120 ppm to 180 ppm zinc chloride, from 120 ppm to 180 ppm zinc chloride and from 120 ppm up to 180 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 130 ppm to 170 ppm zinc chloride, from 130 ppm to 170 ppm zinc chloride and from 130 ppm up to 170 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 140 ppm to 160 ppm zinc chloride, from 140 ppm to 160 ppm zinc chloride and from 140 ppm up to 160 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 150 ppm zinc chloride, 150 ppm zinc chloride and 150 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 150 ppm to 250 ppm copper salt, from 150 ppm to 250 ppm zinc salt and from 150 ppm up to 250 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 160 ppm to 240 ppm copper salt, from 160 ppm to 240 ppm zinc salt and from 160 ppm up to 240 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 170 ppm to 230 ppm copper salt, from 170 ppm to 230 ppm zinc salt and from 170 ppm up to 230 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 180 ppm to 220 ppm copper salt, from 180 ppm to 220 ppm zinc salt and from 180 ppm up to 220 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 190 ppm to 210 ppm copper salt, from 190 ppm to 210 ppm zinc salt and from 190 ppm up to 210 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 200 ppm copper salt, 200 ppm zinc salt and 200 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 150 ppm to 250 ppm zinc chloride, from 150 ppm to 250 ppm zinc chloride and from 150 ppm up to 250 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 160 ppm to 240 ppm zinc chloride, from 160 ppm to 240 ppm zinc chloride and from 160 ppm up to 240 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 170 ppm to 230 ppm zinc chloride, from 170 ppm to 230 ppm zinc chloride and from 170 ppm up to 230 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 180 ppm to 220 ppm zinc chloride, from 180 ppm to 220 ppm zinc chloride and from 180 ppm up to 220 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 190 ppm to 210 ppm

- 67 043933 zinc chloride, from 190 ppm to 210 ppm zinc chloride and from 190 ppm to 210 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 200 ppm zinc chloride,

200 ppm zinc chloride and 200 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 200 ppm to 300 ppm copper salt, from 200 ppm to 300 ppm zinc salt and from 200 ppm up to 300 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 210 ppm to 290 ppm copper salt, from 210 ppm to 290 ppm zinc salt and from 210 ppm up to 290 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 220 ppm to 280 ppm copper salt, from 220 ppm to 280 ppm zinc salt and from 220 ppm up to 280 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 230 ppm to 270 ppm copper salt, from 230 ppm to 270 ppm zinc salt and from 230 ppm up to 270 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 240 ppm to 260 ppm copper salt, from 240 ppm to 260 ppm zinc salt and from 240 ppm up to 260 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 250 ppm copper salt, 250 ppm zinc salt and 250 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 200 ppm to 300 ppm zinc chloride, from 200 ppm to 300 ppm zinc chloride and from 200 ppm up to 300 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 210 ppm to 290 ppm zinc chloride, from 210 ppm to 290 ppm zinc chloride and from 210 ppm up to 290 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 220 ppm to 280 ppm zinc chloride, from 220 ppm to 280 ppm zinc chloride and from 220 ppm up to 280 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 230 ppm to 270 ppm zinc chloride, from 230 ppm to 270 ppm zinc chloride and from 230 ppm up to 270 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 240 ppm to 260 ppm zinc chloride, from 240 ppm to 260 ppm zinc chloride and from 240 ppm up to 260 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 250 ppm zinc chloride, 250 ppm zinc chloride and 250 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 250 ppm to 350 ppm copper salt, from 250 ppm to 350 ppm zinc salt and from 250 ppm up to 350 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 260 ppm to 340 ppm copper salt, from 260 ppm to 340 ppm zinc salt and from 260 ppm up to 340 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 270 ppm to 330 ppm copper salt, from 270 ppm to 330 ppm zinc salt and from 270 ppm up to 330 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 280 ppm to 320 ppm copper salt, from 280 ppm to 320 ppm zinc salt and from 280 ppm up to 320 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 290 ppm to 310 ppm copper salt, from 290 ppm to 310 ppm zinc salt and from 290 ppm up to 310 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 300 ppm copper salt, 300 ppm zinc salt and 300 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 400 ppm to 600 ppm hypochlorous acid or free active chlorine, from 250 ppm to 350 ppm zinc chloride, from 250 ppm to 350 ppm zinc chloride and 250 ppm to 350 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 420 ppm to 580 ppm hypochlorous acid or free active chlorine, from 260 ppm to 340 ppm zinc chloride, from 260 ppm to 340 ppm zinc chloride and from 260 ppm up to 340 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 440 ppm to 560 ppm hypochlorous acid or free active chlorine, from 270 ppm to 330 ppm zinc chloride, from 270 ppm to 330 ppm zinc chloride and from 270 ppm up to 330 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 460 ppm to 540 ppm hypochlorous acid or free active chlorine, from 280 ppm to 320 ppm zinc chloride, from 280 ppm to 320 ppm zinc chloride and from 280 ppm up to 320 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 480 ppm to 520 ppm hypochlorous acid or free active chlorine, from 290 ppm to 310 ppm zinc chloride, from 290 ppm to 310 ppm zinc chloride and from 290 ppm up to 310 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 500 ppm hypochlorous acid or free active chlorine, 300 ppm zinc chloride, 300 ppm zinc chloride and 300 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 50 ppm to 150 ppm copper salt, from 50 ppm to 150 ppm zinc salt and from 50 ppm up to 150 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 60 ppm to 140 ppm copper salt, from 60 ppm to 140 ppm zinc salt and from 60 ppm up to 140 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 70 ppm to 130 ppm copper salt, from 70 ppm to 130 ppm zinc salt and from 70 ppm up to 130 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 80 ppm to 120 ppm copper salt, from 80 ppm to 120 ppm zinc salt and from 80 ppm up to 120 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 90 ppm to 110 ppm copper salt, from 90 ppm to 110 ppm zinc salt and from 90 ppm up to 110 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 100 ppm copper salt, 100 ppm zinc salt and 100 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 50 ppm to 150 ppm zinc chloride, from 50 ppm to 150 ppm zinc chloride and from 50 ppm up to 150 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 60 ppm to 140 ppm zinc chloride, from 60 ppm to 140 ppm zinc chloride and from 60 ppm up to 140 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 70 ppm to 130 ppm zinc chloride, from 70 ppm to 130 ppm zinc chloride and from 70 ppm up to 130 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 80 ppm to 120 ppm zinc chloride, from 80 ppm to 120 ppm zinc chloride and from 80 ppm up to 120 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 90 ppm to 110 ppm zinc chloride, from 90 ppm to 110 ppm zinc chloride and from 90 ppm up to 110 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 100 ppm zinc chloride, 100 ppm zinc chloride and 100 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 100 ppm to 200 ppm copper salt, from 100 ppm to 200 ppm zinc salt and from 100 ppm up to 200 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active

- 69 043933 chlorine, from 110 ppm to 190 ppm copper salts, from 110 ppm to 190 ppm zinc salts and from 110 ppm to 190 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 120 ppm to 180 ppm copper salt, from 120 ppm to 180 ppm zinc salt and from 120 ppm up to 180 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 130 ppm to 170 ppm copper salt, from 130 ppm to 170 ppm zinc salt and from 130 ppm up to 170 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 140 ppm to 160 ppm copper salt, from 140 ppm to 160 ppm zinc salt and from 140 ppm up to 160 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 150 ppm copper salt, 150 ppm zinc salt and 150 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 100 ppm to 200 ppm zinc chloride, from 100 ppm to 200 ppm zinc chloride and from 100 ppm up to 200 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 110 ppm to 190 ppm zinc chloride, from 110 ppm to 190 ppm zinc chloride and from 110 ppm up to 190 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 120 ppm to 180 ppm zinc chloride, from 120 ppm to 180 ppm zinc chloride and from 120 ppm up to 180 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 130 ppm to 170 ppm zinc chloride, from 130 ppm to 170 ppm zinc chloride and from 130 ppm up to 170 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 140 ppm to 160 ppm zinc chloride, from 140 ppm to 160 ppm zinc chloride and from 140 ppm up to 160 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 150 ppm zinc chloride, 150 ppm zinc chloride and 150 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 150 ppm to 250 ppm copper salt, from 150 ppm to 250 ppm zinc salt and from 150 ppm up to 250 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 160 ppm to 240 ppm copper salt, from 160 ppm to 240 ppm zinc salt and from 160 ppm up to 240 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 170 ppm to 230 ppm copper salt, from 170 ppm to 230 ppm zinc salt and from 170 ppm up to 230 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 180 ppm to 220 ppm copper salt, from 180 ppm to 220 ppm zinc salt and from 180 ppm up to 220 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 190 ppm to 210 ppm copper salt, from 190 ppm to 210 ppm zinc salt and from 190 ppm up to 210 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 200 ppm copper salt, 200 ppm zinc salt and 200 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 150 ppm to 250 ppm zinc chloride, from 150 ppm to 250 ppm zinc chloride and from 150 ppm up to 250 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 160 ppm to 240 ppm zinc chloride, from 160 ppm to 240 ppm zinc chloride and from 160 ppm up to 240 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 170 ppm to 230 ppm zinc chloride, from 170 ppm to 230 ppm zinc chloride and from 170 ppm up to 230 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 180 ppm to 220 ppm zinc chloride, from 180 ppm to 220 ppm chlorine

- 70 043933 zinc and 180 ppm to 220 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 190 ppm to 210 ppm zinc chloride, from 190 ppm to 210 ppm zinc chloride and from 190 ppm up to 210 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 200 ppm zinc chloride, 200 ppm zinc chloride and 200 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 200 ppm to 300 ppm copper salt, from 200 ppm to 300 ppm zinc salt and from 200 ppm up to 300 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 210 ppm to 290 ppm copper salt, from 210 ppm to 290 ppm zinc salt and from 210 ppm up to 290 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 220 ppm to 280 ppm copper salt, from 220 ppm to 280 ppm zinc salt and from 220 ppm up to 280 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 230 ppm to 270 ppm copper salt, from 230 ppm to 270 ppm zinc salt and from 230 ppm up to 270 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 240 ppm to 260 ppm copper salt, from 240 ppm to 260 ppm zinc salt and from 240 ppm up to 260 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 250 ppm copper salt, 250 ppm zinc salt and 250 ppm iron salt.

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 200 ppm to 300 ppm zinc chloride, from 200 ppm to 300 ppm zinc chloride and from 200 ppm up to 300 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 210 ppm to 290 ppm zinc chloride, from 210 ppm to 290 ppm zinc chloride and from 210 ppm up to 290 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 220 ppm to 280 ppm zinc chloride, from 220 ppm to 280 ppm zinc chloride and from 220 ppm up to 280 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 230 ppm to 270 ppm zinc chloride, from 230 ppm to 270 ppm zinc chloride and from 230 ppm up to 270 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 240 ppm to 260 ppm zinc chloride, from 240 ppm to 260 ppm zinc chloride and from 240 ppm up to 260 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 250 ppm zinc chloride, 250 ppm zinc chloride and 250 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 250 ppm to 350 ppm copper salt, from 250 ppm to 350 ppm zinc salt and from 250 ppm up to 350 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 260 ppm to 340 ppm copper salt, from 260 ppm to 340 ppm zinc salt and from 260 ppm up to 340 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 270 ppm to 330 ppm copper salt, from 270 ppm to 330 ppm zinc salt and from 270 ppm up to 330 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 280 ppm to 320 ppm copper salt, from 280 ppm to 320 ppm zinc salt and from 280 ppm up to 320 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 290 ppm to 310 ppm copper salt, from 290 ppm to 310 ppm zinc salt and from 290 ppm up to 310 ppm iron salts. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 300 ppm copper salt, 300 ppm zinc salt and 300 ppm iron salt.

- 71 043933

In one aspect, according to this embodiment, the composition described in the present invention contains from 1 ppm to 50 ppm hypochlorous acid or free active chlorine, from 250 ppm to 350 ppm zinc chloride, from 250 ppm to 350 ppm zinc chloride and from 250 ppm up to 350 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 5 ppm to 45 ppm hypochlorous acid or free active chlorine, from 260 ppm to 340 ppm zinc chloride, from 260 ppm to 340 ppm zinc chloride and from 260 ppm up to 340 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 10 ppm to 40 ppm hypochlorous acid or free active chlorine, from 270 ppm to 330 ppm zinc chloride, from 270 ppm to 330 ppm zinc chloride and from 270 ppm up to 330 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 15 ppm to 35 ppm hypochlorous acid or free active chlorine, from 280 ppm to 320 ppm zinc chloride, from 280 ppm to 320 ppm zinc chloride and from 280 ppm up to 320 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains from 20 ppm to 30 ppm hypochlorous acid or free active chlorine, from 290 ppm to 310 ppm zinc chloride, from 290 ppm to 310 ppm zinc chloride and from 290 ppm up to 310 ppm ferric chloride. In one aspect, according to this embodiment, the composition described in the present invention contains 25 ppm hypochlorous acid or free active chlorine, 300 ppm zinc chloride, 300 ppm zinc chloride and 300 ppm ferric chloride. The ferric chloride may be ferric chloride (II) or ferric chloride (III).

Aspects of the present invention describe a kit. In one embodiment, the kit may include a container containing a composition described in the present invention. In another embodiment, the kit may include one or more containers, each of the containers containing an individual component or a combination of more than one individual components described in the present invention. For example, the kit may include a first container containing hypochlorous acid or free active chlorine and a second container containing one or more metal particles. As another example, the kit may include a first container containing hypochlorous acid or free active chlorine and a second container containing mixed copper-zinc-iron oxide particles. As another example, the kit may include a first container containing one or more alcohols and a second container containing one or more compounds containing a guanide moiety. As another example, the kit may include a first container containing isopropanol and a second container containing polyhexamethylene biguanide. As another example, the kit may include a first container containing hypochlorous acid or free active chlorine and a second container containing one or more quaternary compounds or organosilicon quaternary compounds. As another example, the kit may include a first container containing hypochlorous acid or free active chlorine and a second container containing dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride. The remaining components of the composition described in the present invention may be contained in the first or second container, or may be separately contained in at least a third container. For example, the kit may include a third container containing the rinsing solution described in the present invention. Packaging individual components in a separate container can help extend the stability of the individual components and thus increase the shelf life of the product.

In another example, the kit may include a first container containing hypochlorous acid and/or free active chlorine, a second container containing one or more metal particles, and a third container containing a rinse solution. As another example, the kit may include a first container containing hypochlorous acid and/or free active chlorine, a second container containing mixed copper-zinc-iron oxide particles, and a third container containing a rinsing solution. As another example, the kit may include a first container containing one or more alcohols, a second container containing one or more guanide moiety-containing compounds, and a third container containing a wash solution. As another example, the kit may include a first container containing isopropanol, a second container containing polyhexamethylene biguanide, and a third container containing a rinse solution. As another example, the kit may include a first container containing hypochlorous acid or free active chlorine, a second container containing one or more quaternaries or organosilicon quaternaries, and a third container containing a rinse solution. As another example, the kit may include a first container containing hypochlorous acid or free active chlorine, a second container containing dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride, and a third container containing a rinse solution. As another example, the kit may include a first container containing isopropanol, a second container containing polyhexamethylene biguanide, a third container containing one or more cationic surfactants, and a fourth container containing a wash solution.

In another embodiment, the kit may include a first container containing a composition described in the present invention and a second container containing a rinse solution described

- 72 043933 ny in the present invention. For example, the kit may include a first container containing hypochlorous acid and/or free active chlorine and one or more metal particles, and a second container containing a rinsing solution. As another example, the kit may include a first container containing hypochlorous acid and/or free active chlorine and mixed copper-zinc-iron oxide particles and a second container containing a rinsing solution. As another example, the kit may include a first container containing one or more alcohols and one or more guanide moiety-containing compounds, and a second container containing a wash solution. As another example, the kit may include a first container containing isopropanol and polyhexamethylene biguanide and a second container containing a rinse solution. As another example, the kit may include a first container containing hypochlorous acid and/or free active chlorine and one or more quaternary compounds or organosilicon quaternary compounds, and a second container containing a rinsing solution. As another example, the kit may include a first container containing hypochlorous acid and/or free active chlorine and dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride and a second container containing a rinse solution. The remaining components of the composition described in the present invention may be contained in the first container or may be separately contained in at least a third container. Packaging individual components in a separate container can help extend the stability of the individual components and thus increase the shelf life of the product.

The kit described in the present invention may include a delivery or application system. A delivery or application kit system is useful for applying the composition described in the present invention and/or the individual components described in the present invention to an area of interest, such as, for example, the surface of a device described in the present invention. The delivery or application system described in the present invention includes, without limitation, one or more applicator brushes, foam swabs or wipes, hollow tubes, test strips, or a combination thereof. In one embodiment, the kit includes one delivery or application system. In another embodiment, the kit includes a plurality of delivery or application systems. For example, a 30-day kit may include 30 delivery or application systems, such that one delivery or application system is provided for each of the 30 days. Alternatively, the set may include 2, 10, 20, 30, 40, 50, 60, 90, 120, etc. delivery or application systems. The included delivery or application system may be packaged individually or in sets of 2 or more. The delivery or application system may be packaged to remain sterile until use. In some embodiments, the delivery or application system described in the present invention can be packaged in plastic containers. In addition, to prevent contamination, the delivery or application system described in the present invention is preferably a disposable delivery or application system.

The kit may also include a set of instructions. The instructions may include information useful to the end user, such as a description of the use of the delivery or application system for applying the composition and/or individual components described in the present invention, and/or a description of the frequency of application of the composition and/or individual components described in the present invention. In addition, such instructions may include information on how to mix the individual components described in the present invention to obtain the composition described in the present invention. Such instructions may indicate that mixing should be carried out at a certain time before application, such as, for example, immediately before use. The instructions described in the present invention may also include information on how to apply the individual components described in the present invention directly to an area of interest, such as, for example, the surface of a device described in the present invention, and in what order the individual components should be applied to such areas of interest.

The contents of the kit, including the container containing the composition or component described in the present invention, the delivery or application system and instructions, are placed in an outer housing. The outer casing may be a box, a sealed bag, a foil sachet, etc. In some embodiments, the delivery system, container, and instructions are contained within a box. In other embodiments of the kit, the container and instructions are placed in a first box, the delivery system is placed in a second box, and the first and second boxes are placed together in a third box.

The compositions described in the present invention are suitable for any application involving cleaning, disinfection or sterilization. In one embodiment, the composition described in the present invention is used to clean, disinfect or sterilize a device. In one embodiment, the composition described in the present invention is used to clean, disinfect or sterilize an endoscope. In one embodiment, the composition described in the present invention is used to clean, disinfect or sterilize a hard surface. In one embodiment, the composition described in the present invention is suitable for any application in which hypochlorous acid is applied or administered.

Aspects of the present invention describe a method for cleaning, disinfecting and/or

- 73 043933 sterilization of the device. In one embodiment, the method described in the present invention includes applying a composition described in the present invention to a device for a specified period of time, the application resulting in cleaning, disinfection and/or sterilization of the device. In another aspect, according to this embodiment, the method described in the present invention further includes washing the cleaned, disinfected and/or sterilized device with a washing solution described in the present invention. In other aspects, the present invention provides a composition described in the present invention for use in cleaning, disinfecting and/or sterilizing a device, including a medical device. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a device, including a medical device.

Aspects of the present invention describe a method for cleaning, disinfecting and/or sterilizing an endoscope. In one aspect, according to this embodiment, the method described in the present invention includes applying a composition described in the present invention to an endoscope for a specified period of time, the application resulting in cleaning, disinfection and/or sterilization of the endoscope. In another aspect, according to this embodiment, the method described in the present invention further includes washing the cleaned, disinfected and/or sterilized endoscope with a rinsing solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing an endoscope. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing an endoscope.

A device, including a medical device, is cleaned by removing visible contaminants, such as, for example, organic and inorganic material, from objects and surfaces, and cleaning is typically performed manually or mechanically. Thorough cleaning is necessary before disinfection and sterilization because inorganic and organic materials that remain on medical device surfaces impair the effectiveness of these processes.

A device, including a medical device, is disinfected by destroying many or all pathogenic microorganisms, excluding bacterial spores. Disinfection is less destructive than sterilization because it destroys most recognized pathogens, but not necessarily all microbial forms (eg, bacterial spores). A medical device is sterilized by killing or eliminating all forms of microorganisms. Medical device decontamination removes pathogenic microorganisms from the medical device so that it can be safely used, applied, or disposed of.

A medical device is an instrument, apparatus, material or other article that can be used individually or in combination, including software necessary for its use, intended by the manufacturer for use in humans to diagnose, prevent, monitor the treatment or alleviate a disease; diagnosing, monitoring, treating or alleviating an injury or defect or compensating for the consequences of an injury or defect; research, replacement or modification of anatomy or physiological process; or management of conception, and for processes which do not achieve their primary intended action in or on the human body by pharmacological, immunological or metabolic means, but may be assisted in their functioning by such means. The medical device includes, but is not limited to, a surgical instrument, a respiratory therapy instrument, an anesthesia instrument, a catheter, an implant, a probe, an endoscope, an arthroscope, a laparoscope, a blade, a cystoscope, a spirometer, a CPAP therapy mask and tubing, and a dialysis instrument and components. , heart-lung machine for ECMO and its components, heart-lung machine and accessories for it, and a ring for adjusting the diaphragm. Non-limiting examples of probes include an ultrasound probe and an esophageal manometry probe. Non-limiting examples of catheters include a cardiac catheter, a urinary catheter, an anorectal manometry catheter. Non-limiting examples of endoscopes include a gastrointestinal endoscope, a bronchoscope, and a nasopharyngoscope. Non-limiting examples of blades include a laryngoscope blade.

Aspects of the present invention describe a method for cleaning, disinfecting and/or sterilizing a hard surface area. In one aspect, according to this embodiment, the method described in the present invention includes applying a composition described in the present invention to an area of a hard surface for a specified period of time, wherein the application results in cleaning, disinfecting and/or sterilizing the area of the hard surface. In another aspect, according to this embodiment, the method described in the present invention further includes washing the cleaned, disinfected and/or sterilized surface with a rinsing solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing a hard surface area. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a hard surface area. The solid surface region may be a porous surface region or a non-porous surface region.

In another aspect, according to this embodiment, the method described in the present invention includes applying one or more of the individual components described in the present invention to an area of a hard surface for a specified period of time, wherein the application results in cleaning, disinfecting and/or sterilizing the area of the hard surface. surfaces. In one aspect, according to this embodiment, the one or more separate components include a first component containing hypochlorous acid or free active chlorine, and a second component containing one or more disinfectant agents. In another aspect, application of one or more individual components occurs in a specific order, such as, for example, first applying a first component containing hypochlorous acid or free active chlorine, and then applying a second component containing one or more disinfectant agents. The solid surface region may be a porous surface region or a non-porous surface region.

The hard surface area may include any items found in a residential or commercial, industrial and/or agricultural establishment, such as, for example, a hospital, laboratory, restaurant, training center, food processing plant, dairy processing plant, airport, oil field system, sports complex, shipping port, freight transportation center, and any other commercial or industrial facility. The surface area may include any type of vehicle, such as, for example, a watercraft such as a boat, barge or ship, an aircraft such as an airplane or helicopter, a land vehicle such as a motorcycle, car, truck or train. The surface area can be made of any material, including brass, copper, aluminum, stainless steel, carbon steel, rubber, plastic, glass, wood, painted surface, or any combination thereof. Surface area includes, but is not limited to, table top, countertop, floor, wall, ceiling, window, bed, gurney, door, door handle, shower, bathtub, sink, faucet, toilet, toilet seat, drain, equipment, appliances, facilities personal protective equipment, personal biological protection equipment, etc.

The surface area may include a medical, dental, pharmaceutical, veterinary, or mortuary device. The surface area may include human skin.

The composition or component described in the present invention can be applied to an area of a hard surface in accordance with the method described in the present invention, as often as necessary and/or desired. The composition described in the present invention can be applied to a hard surface area daily, every other day, every other day, once a week, several times a week, once a month, several times a month, once a year or several times a year, according to desire. The composition described in the present invention can be applied to a hard surface area several times a day, for example, twice a day, three times a day, four times a day, five times a day, six times a day, or as often as possible. desirable.

The compositions described in the present invention are suitable for any application involving the treatment of a patient. The compositions described in the present invention are suitable for any use, including medical use, veterinary use, or both. In one embodiment, the composition described in the present invention is suitable for any application in which hypochlorous acid is applied or administered.

In one embodiment, the compositions described herein are suitable for any application involving the treatment of patient tissue. For example, the compositions described in the present invention can be used to treat a wound by enhancing angiogenesis in the area in and around the wound or promoting rapid wound healing.

In one embodiment, the compositions described herein are suitable for any application involving the treatment of a wound on a patient. For example, the compositions described in the present invention can be used to treat a wound by enhancing angiogenesis in the area in and around the wound or promoting rapid wound healing. The wound may be an open wound, a closed wound, or a burn. Non-limiting examples of open wounds include cut, scrape, laceration, puncture wound, avulsion, ulcer and tear. Non-limiting examples of closed wounds include bruise, contusion, and hematoma.

Aspects of the present invention describe a method for cleaning, disinfecting and/or sterilizing a wound on a patient. In one aspect, according to this embodiment, the method described in the present invention includes applying a composition described in the present invention to a wound for a specified period of time, the application resulting in cleaning, disinfecting and/or sterilizing the wound. In another aspect, according to this embodiment, the method described in the present invention further includes rinsing the cleaned, disinfected and/or sterilized wound with a rinse solution described in the present invention. In other aspects, the present invention provides a composition described in the present invention for use in cleaning, disinfecting and/or sterilizing a wound. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a wound.

In aspects of the present invention, a method of treating a wound in a patient is described. In one aspect, according to this embodiment, the method described in the present invention includes applying a composition described in the present invention to a wound for a certain period of time, and the application promotes healing of the wound. In another aspect, according to this embodiment, the method described in the present invention further includes washing the treated wound with a rinse solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in treating a wound. In other aspects, the present invention describes the use of the described composition for the treatment of a wound. The wound may be an external wound, such as on a surface area of the patient, or an internal wound located in the body or body cavity of the patient.

In one embodiment, the compositions described herein are suitable for any application involving a microbial infection in a patient. Microbial infection includes viral infection, bacterial infection and fungal infection. A microbial infection can be an external infection, such as on a patient's surface area, or an internal infection, such as a Mercer infection or sepsis, located in the patient's body or body cavity.

Aspects of the present invention describe a method for cleaning, disinfecting and/or sterilizing a microbial infection in a patient. In one aspect, according to this embodiment, the method described in the present invention includes the use of a composition described in the present invention on a microbial infection for a certain period of time, the application resulting in cleaning, disinfection and/or sterilization of the microbial infection. In another aspect, according to this embodiment, the method described in the present invention further includes washing the purified, disinfected and/or sterilized microbial infection with a washing solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing a microbial infection. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a microbial infection.

In one embodiment, the composition described in the present invention is used to clean, disinfect or sterilize a part of a patient's body. Non-limiting examples of uses of the composition described in the present invention include tissue cleaning/disinfection in wound care, preoperative preparation and surgery or other invasive procedure, skin area cleaning/disinfection in dermatological applications, and eye cleaning/disinfection in ophthalmic applications.

In aspects of the present invention, a method of treating a microbial infection in a patient is described. In one aspect, according to this embodiment, the method described in the present invention includes the use of a composition described in the present invention on a microbial infection for a certain period of time, the application resulting in the reduction, elimination and/or destruction of microbes causing the microbial infection. In another aspect, according to this embodiment, the method described in the present invention further includes washing the treated microbial infection with a washing solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in treating a microbial infection. In other aspects, the present invention describes the use of the described composition for the treatment of a microbial infection.

Dermatological application refers to the cleaning/disinfection of an area of skin of a patient with a microbial infection, such as, for example, a viral, bacterial or fungal infection. Non-limiting examples of microbial infections of the skin area include urinary tract infection, eyelid cleanser and cataract treatment infections, warts, cutaneous leishmaniasis, vulvovaginal candidiasis, dermatophytosis, bromhidrosis, lichen versicolor, juvenile acne, rosacea, hidradenitis suppurativa, psoriasis, eczema , alopecia areata, oral lichen planus, xeroderma pigmentosum, actinic kerotosis, melasma, keloids and infections acquired during anti-aging procedures.

Ophthalmic use relates to cleaning/disinfecting the eye of a patient with a microbial infection, such as, for example, a viral, bacterial or fungal infection. Non-limiting examples of microbial infections of the eye include bacterial conjunctivitis, viral conjunctivitis, epidemic keratoconjunctivitis, pharyngoconjunctival fever, styes, blepharitis, episcleritis, keratitis, trachoma and corneal ulcers.

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The compositions described herein are suitable for any use involving treating and/or providing relief from inflammation, aches and/or pain in a patient.

Aspects of the present invention describe a method of treating inflammation, aches and/or pain in a patient. In one aspect, according to this embodiment, the method described in the present invention includes applying a composition described in the present invention to an area of inflammation, aches and/or pain for a certain period of time, the application resulting in relief and/or elimination of pain. In another aspect, according to this embodiment, the method described in the present invention further includes washing the treated area with a rinse solution described in the present invention. In other aspects, the present invention provides a composition described herein for use in treating inflammation, aches and/or pain. In other aspects, the present invention describes the use of the described composition for the treatment of inflammation, aches and/or pain.

The compositions described in the present invention are suitable for enteral and parenteral use, including oral, injectable and topical use. For example, the compositions described in the present invention can be used to clean, disinfect or sterilize an area of the body that has been damaged by a wound or infected with a microbe.

In one aspect, according to this embodiment, the method described in the present invention includes the use of a composition described in the present invention on a patient for a certain period of time, the use resulting in the cleaning, disinfection and/or sterilization of a microbial infection in the patient. In other aspects, the present invention provides a composition described herein for use in cleaning, disinfecting, and/or sterilizing a microbial infection in a patient. In other aspects, the present invention describes the use of the described composition for cleaning, disinfecting and/or sterilizing a microbial infection in a patient. In other aspects, the present invention provides a composition described herein for the production of a medicament for cleaning, disinfecting and/or sterilizing a microbial infection in a patient.

In the method and/or use described in the present invention, the composition described in the present invention is used on a patient. The patient is any animal, including, without limitation, a fish, amphibian, bird or mammal. Mammal includes human, horse, cow, sheep, dog and cat. Thus, the method described in the present invention is intended for use in humans as well as for veterinary use.

When used on a patient, the composition described in the present invention can be applied to the surface of the skin or can be administered orally. In one embodiment, the composition described in the present invention is applied topically to an area of the patient's skin to clean, disinfect and/or sterilize the area of skin. The skin area includes, but is not limited to, the face, forehead, lips, scalp, neck, shoulders, arms, hands, thighs, legs, knees, feet, chest, chest, back, groin, buttocks, and the like.

In one embodiment, the composition described in the present invention is intended for internal use by a patient. Such routes of administration include enteral routes of administration and parenteral routes of administration.

The composition described in the present invention can be applied in accordance with the method described in the present invention to an area of the skin. Application of the composition described in the present invention can be carried out by rubbing, pouring, spraying or dispersing or otherwise applying to the human body. The composition described in the present invention can be applied by introducing the composition into or onto a solid support, such as, for example, a napkin, wet wipe, towel, mitten, glove or mask, and then applying the composition to the skin area. The composition described in the present invention can be applied using a delivery device, such as, for example, an aerosol spray, a spray bottle, a trigger spray, a squeeze bottle, a topical patch, a transdermal patch, or a dermal implant, to apply the composition to an area of the skin.

The composition described in the present invention can be administered to a patient in accordance with the method described in the present invention, as often as necessary and/or desired. The composition described in the present invention can be administered to a patient daily, every other day, every other day, once a week, several times a week, once a month, several times a month, once a year, or several times a year, as desired. The composition described in the present invention can be administered to a patient several times a day, for example, twice a day, three times a day, four times a day, five times a day, six times a day, or as often as desired.

The compositions described in the present invention are suitable for use in the production of food products, poultry, meat, and vegetables. For example, the compositions described in the present invention can be used to clean, disinfect or sterilize equipment, instruments, tables, rooms, including floors, ceilings and walls, and any other hard surfaces from microbial contamination.

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The compositions described in the present invention are suitable for use in plant formulations as a preservative or pesticide. For example, the compositions described in the present invention can be used to clean, disinfect or sterilize a plant that has been wounded or infected with a microbe.

The compositions described in the present invention are suitable for use in cut flower formulations to prolong the period of freshness and health. For example, the compositions described in the present invention can be used to clean, disinfect or sterilize a cut flower or to prevent microbial infection.

In the described method and/or application, the composition described in the present invention is applied for a certain period of time. In one embodiment, the specified period of time is a time sufficient to clean the medical device, surface, or patient. In another embodiment, the specified period of time is a time sufficient to disinfect the medical device, surface, or patient. In another embodiment, the specified period of time is a time sufficient to sterilize the medical device, surface, or patient.

In aspects according to this embodiment, the composition described in the present invention is applied to a device, such as a medical device, surface, or applied to a patient for a period of time of, for example, about 1 minute, about 5 minutes, about 10 minutes, about 15 min, about 20 min, about 25 min, about 30 min, about 35 min, about 40 min, about 45 min, about 50 min, about 55 min, about 60 min, about 70 min, about 80 min, about 90 min, about 100 minutes, about 110 minutes or about 120 minutes. In other aspects, according to this embodiment, the composition described in the present invention is applied to a device, such as a medical device, a surface, or applied to a patient for a period of time of, for example, at least 1 minute, at least 5 minutes, at least 10 minutes, at least 15 minutes, at least 20 minutes, at least 25 minutes, at least 30 minutes, at least 35 minutes, at least 40 minutes, at least 45 minutes, at least 50 minutes, at least 55 minutes, at least 60 minutes, at least 70 minutes, at least 80 minutes, at least 90 minutes, at least 100 minutes, at least 110 minutes or at least 120 minutes . In other aspects, according to this embodiment, the composition described in the present invention is applied to a device, such as a medical device, surface, or applied to a patient for a period of time of, for example, no more than 1 minute, no more than 5 minutes, no more than 10 min, no more than 15 minutes, no more than 20 minutes, no more than 25 minutes, no more than 30 minutes, no more than 35 minutes, no more than 40 minutes, no more than 45 minutes, no more than 50 minutes, no more than 55 minutes, no more than 60 min, no more than 70 minutes, no more than 80 minutes, no more than 90 minutes, no more than 100 minutes, no more than 110 minutes or no more than 120 minutes.

In other aspects, according to this embodiment, the composition described in the present invention is applied to a device, such as a medical device, surface, or applied to a patient for a period of time of, for example, from about 1 minute to about 5 minutes, from about 1 minute to about 10 minutes, from about 1 minute to about 15 minutes, from about 1 minute to about 20 minutes, from about 1 minute to about 25 minutes, from about 1 minute to about 30 minutes, from about 1 minute to about 35 minutes, from about 1 minute to about 40 minutes, from about 1 minute to about 45 minutes, from about 1 minute to about 50 minutes, from about 1 minute to about 55 minutes, from about 1 minute to about 60 minutes, from about 5 minutes to about 10 minutes, from about 5 minutes to about 15 minutes, from about 5 minutes to about 20 minutes, from about 5 minutes to about 25 minutes, from about 5 minutes to about 30 minutes, from about 5 minutes to about 35 minutes, from about 5 minutes to about 40 minutes, about 5 minutes to about 45 minutes, about 5 minutes to about 50 minutes, about 5 minutes to about 55 minutes, about 5 minutes to about 60 minutes, about 5 minutes to about 70 minutes, from about 5 minutes to about 80 minutes, from about 5 minutes to about 90 minutes, from about 5 minutes to about 100 minutes, from about 5 minutes to about 110 minutes, from about 5 minutes to about 120 minutes, from about 10 minutes to about 15 minutes, from about 10 minutes to about 20 minutes, from about 10 minutes to about 25 minutes, from about 10 minutes to about 30 minutes, from about 10 minutes to about 35 minutes, from about 10 minutes to about 40 min, from about 10 min to about 45 min, from about 10 min to about 50 min, from about 10 min to about 55 min, from about 10 min to about 60 min, from about 10 min to about 70 min, from about 10 min to about 80 min, from about 10 min to about 90 min, from about 10 min to about 100 min, from about 10 min to about 110 min, from about 10 min to about 120 min, from about 15 min to about 20 min , from about 15 minutes to about 25 minutes, from about 15 minutes to about 30 minutes, from about 15 minutes to about 35 minutes, from about 15 minutes to about 40 minutes, from about 15 minutes to about 45 minutes, from about 15 minutes to about 50 minutes, from about 15 minutes to about 55 minutes, from about 15 minutes to about 60 minutes, from about 15 minutes to about 70 minutes, from about 15 minutes to about 80 minutes, from about 15 minutes to about 90 minutes, from about 15 minutes to about 100 minutes, from about 15 minutes to about 110 minutes, from about 15 minutes to about 120 minutes, from about 20 minutes to about

- 78 043933 min, from about 20 min to about 30 min, from about 20 min to about 35 min, from about 20 min to about 40 min, from about 20 min to about 45 min, from about 20 min to about 50 min, from about 20 minutes to about 55 minutes, from about 20 minutes to about 60 minutes, from about 20 minutes to about 70 minutes, from about 20 minutes to about 80 minutes, from about 20 minutes to about 90 minutes, from about 20 minutes to about 100 minutes, from about 20 minutes to about 110 minutes, from about 20 minutes to about 120 minutes, from about 25 minutes to about 30 minutes, from about 25 minutes to about 35 minutes, from about 25 minutes to about 40 minutes, from about 25 minutes to about 45 minutes, about 25 minutes to about 50 minutes, about 25 minutes to about 55 minutes, about 25 minutes to about 60 minutes, about 25 minutes to about 70 minutes, about 25 minutes to about 80 minutes, from about 25 minutes to about 90 minutes, from about 25 minutes to about 100 minutes, from about 25 minutes to about 110 minutes, from about 25 minutes to about 120 minutes, from about 30 minutes to about 35 minutes, from about 30 minutes to about 40 minutes, from about 30 minutes to about 45 minutes, from about 30 minutes to about 50 minutes, from about 30 minutes to about 55 minutes, from about 30 minutes to about 60 minutes, from about 30 minutes to about 70 min, from about 30 min to about 80 min, from about 30 min to about 90 min, from about 30 min to about 100 min, from about 30 min to about 110 min, from about 30 min to about 120 min, from about 35 min to about 40 min, from about 35 min to about 45 min, from about 35 min to about 50 min, from about 35 min to about 55 min, from about 35 min to about 60 min, from about 35 min to about 70 min , from about 35 minutes to about 80 minutes, from about 35 minutes to about 90 minutes, from about 35 minutes to about 100 minutes, from about 35 minutes to about 110 minutes, from about 35 minutes to about 120 minutes, from about 40 minutes to about 45 minutes, from about 40 minutes to about 50 minutes, from about 40 minutes to about 55 minutes, from about 40 minutes to about 60 minutes, from about 40 minutes to about 70 minutes, from about 40 minutes to about 80 minutes, from about 40 minutes to about 90 minutes, from about 40 minutes to about 100 minutes, from about 40 minutes to about 110 minutes, from about 40 minutes to about 120 minutes, from about 45 minutes to about 50 minutes, from about 45 minutes to about 55 minutes, from about 45 minutes to about 60 minutes, from about 45 minutes to about 70 minutes, from about 45 minutes to about 80 minutes, from about 45 minutes to about 90 minutes, from about 45 minutes to about 100 minutes, from from about 45 minutes to about 110 minutes, from about 45 minutes to about 120 minutes, from about 50 minutes to about 55 minutes, from about 50 minutes to about 60 minutes, from about 50 minutes to about 70 minutes, from about 50 minutes to about 80 minutes, from about 50 minutes to about 90 minutes, from about 50 minutes to about 100 minutes, from about 50 minutes to about 110 minutes, from about 50 minutes to about 120 minutes, from about 55 minutes to about 60 minutes, from about 55 minutes to about 70 minutes, about 55 minutes to about 80 minutes, about 55 minutes to about 90 minutes, about 55 minutes to about 100 minutes, about 55 minutes to about 110 minutes, about 55 minutes to about 120 min, from about 60 min to about 70 min, from about 60 min to about 80 min, from about 60 min to about 90 min, from about 60 min to about 100 min, from about 60 min to about 110 min, from about 60 min to about 120 min, from about 70 min to about 80 min, from about 70 min to about 90 min, from about 70 min to about 100 min, from about 70 min to about 110 min, from about 70 min to about 120 min , from about 80 minutes to about 90 minutes, from about 80 minutes to about 100 minutes, from about 80 minutes to about 110 minutes, from about 80 minutes to about 120 minutes, from about 90 minutes to about 100 minutes, from about 90 minutes to about 110 minutes, from about 90 minutes to about 120 minutes, from about 100 minutes to about 110 minutes, from about 100 minutes to about 120 minutes, or from about 110 minutes to about 120 minutes.

The described composition, method and/or use are less destructive to the medical device, resulting in a longer service life of the medical device. In aspects according to this embodiment, the medical device can be cleaned, disinfected and/or sterilized, for example, about 50 times, about 60 times, about 70 times, about 80 times, about 90 times, about 100 times, about 110 times, about 120 times , about 130 times, about 140 times, about 150 times, about 160 times, about 170 times, about 180 times, about 190 times, about 200 times, about 210 times, about 220 times, about 230 times, about 240 times, about 250 times, about 260 times, about 270 times, about 280 times, about 290 times, or about 300 times. In other aspects, according to this embodiment, the medical device can be cleaned, disinfected and/or sterilized, for example, at least 50 times, at least 60 times, at least 70 times, at least 80 times, at least 90 times, at least 100 times, at least 110 times, at least 120 times, at least 130 times, at least

140 times, at least 150 times, at least 160 times, at least 170 times, at least

180 times, at least 190 times, at least 200 times, at least 210 times, at least

220 times, at least 230 times, at least 240 times, at least 250 times, at least

260 times, at least 270 times, at least 280 times, at least 290 times or at least 300 times. In other aspects, according to this embodiment, the medical device can be cleaned, disinfected and/or sterilized, for example, no more than 50 times, no more than 60 times, no more than 70 times, no more than 80 times, no more than 90 times, no more than 100 times, no more than 110 times, no more than 120 times, no more than 79 043933 no more than 130 times, no more than 140 times, no more than 150 times, no more than 160 times, no more than 170 times, no more than 180 times, no more than 190 times, no more than 200 times, no more than 210 times, no more than 220 times, no more than 230 times, no more than 240 times, no more than 250 times, no more than 260 times, no more than 270 times, no more than 280 times, no more than 290 times or not more than 300 times.

In other aspects, according to this embodiment, the medical device can be cleaned, disinfected and/or sterilized, for example, from about 50 times to about 60 times, from about 50 times to about 70 times, from about 50 times to about 80 times, from about 50 times to about 90 times, about 50 times to about 100 times, about 50 times to about 110 times, about 50 times to about 120 times, about 50 times to about 130 times, about 50 times to about 140 times , from about 50 times to about 150 times, from about 50 times to about 175 times, from about 50 times to about 200 times, from about 50 times to about 225 times, from about 50 times to about 250 times, from about 50 times to about 275 times, from about 50 times to about 300 times, from about 75 times to about 90 times, from about 75 times to about 100 times, from about 75 times to about 110 times, from about 75 times to about 120 times, from about 75 times to about 130 times, from about 75 times to about 140 times, from about 75 times to about 150 times, from about 75 times to about 175 times, from about 75 times to about 200 times, from about 75 times to about 225 times, about 75 times to about 250 times, about 75 times to about 275 times, about 75 times to about 300 times, about 100 times to about 110 times, about 100 times to about 120 times, about about 100 times to about 130 times, about 100 times to about 140 times, about 100 times to about 150 times, about 100 times to about 175 times, about 100 times to about 200 times, about 100 times to about 225 times, about 100 times to about 250 times, about 100 times to about 275 times, about 100 times to about 300 times, about 125 times to about 150 times, about 125 times to about 175 times, about 125 times to about 200 times, about 125 times to about 225 times, about 125 times to about 250 times, about 125 times to about 275 times, about 125 times to about 300 times, about 150 times to about 175 times times, from about 150 times to about 200 times, from about 150 times to about 225 times, from about 150 times to about 250 times, from about 150 times to about 275 times, from about 150 times to about 300 times, from about 175 times to about 200 times, about 175 times to about 225 times, about 175 times to about 250 times, about 175 times to about 275 times, about 175 times to about 300 times, about 200 times to about 225 times , from about 200 times to about 250 times, from about 200 times to about 275 times, from about 200 times to about 300 times, from about 225 times to about 250 times, from about 225 times to about 275 times, from about 225 times to about 300 times, from about 250 times to about 275 times, from about 250 times to about 300 times, or from about 275 times to about 300 times.

The method described in the present invention may further include a washing step using a washing solution. Typically, a rinse solution is used to rinse a cleaned, disinfected and/or sterilized medical device or surface. The rinsing solution is preferably a sterile solution. In one embodiment, the rinse solution described in the present invention contains water. In another embodiment, the rinse solution described in the present invention contains hypochlorous acid or free active chlorine and water. In another embodiment, the rinse solution described in the present invention does not contain hypochlorous acid and/or free active chlorine. When present in the kit described in the present invention, the rinse solution is contained in a separate container.

The amount of hypochlorous acid or free active chlorine contained in the wash solution described in the present invention is any amount that provides an antimicrobial effect, provided that the total amount of hypochlorous acid or free active chlorine contained is an amount that is less than the threshold level , which results in oxidation of the medical device or surface as described in the present invention. In aspects of this embodiment, the amount of hypochlorous acid or free active chlorine contained in the rinsing solution may be, for example, about 5 ppm, about 10 ppm, about 20 ppm, about 30 ppm, about 40 ppm, about 50 ppm, about 60 ppm, about 70 ppm, about 80 ppm, about 90 ppm, about 100 ppm, about 110 ppm or about 120 ppm. In other aspects, according to this embodiment, the amount of hypochlorous acid or free active chlorine contained in the rinsing solution may be, for example, no more than 5 ppm, no more than 10 ppm, no more than 20 ppm, no more than 30 ppm, no more than 40 ppm , no more than 50 ppm, no more than 60 ppm, no more than 70 ppm, no more than 80 ppm, no more than 90 ppm, no more than 100 ppm, no more than 110 ppm or no more than 120 ppm. In other aspects, according to this embodiment, the amount of hypochlorous acid or free active chlorine contained in the rinsing solution may be, for example, from about 5 ppm to about 10 ppm, from about 5 ppm to about 20 ppm, from about 5 ppm to about 30 ppm, from about 5 ppm to about 40 ppm, from about 5 ppm to about 50 ppm, from about 5 ppm to about 60 ppm, from about 5 ppm to about 70 ppm, from about 5 ppm to about

- 80 043933 ppm, from about 5 ppm to about 90 ppm, from about 5 ppm to about 100 ppm, from about 5 ppm to about 110 ppm, from about 5 ppm to about 120 ppm, from about 10 ppm to about 20 ppm, from about 10 ppm to about 30 ppm, from about 10 ppm to about 40 ppm, from about 10 ppm to about 50 ppm, from about 10 ppm to about 60 ppm, from about 10 ppm to about 70 ppm, from about 10 ppm to about 80 ppm, from about 10 ppm to about 90 ppm, from about 10 ppm to about 100 ppm, from about 10 ppm to about 110 ppm, from about 10 ppm to about 120 ppm, from about 20 ppm to about 30 ppm, from about 20 ppm to about 40 ppm, about 20 ppm to about 50 ppm, about 20 ppm to about 60 ppm, about 20 ppm to about 70 ppm, about 20 ppm to about 80 ppm, about 20 ppm to about 90 ppm, from about 20 ppm to about 100 ppm, from about 20 ppm to about 110 ppm, from about 20 ppm to about 120 ppm, from about 30 ppm to about 40 ppm, from about 30 ppm to about 50 ppm, from about 30 ppm to about 60 ppm, from about 30 ppm to about 70 ppm, from about 30 ppm to about 80 ppm, from about 30 ppm to about 90 ppm, from about 30 ppm to about 100 ppm, from about 30 ppm to about 110 ppm, from about 30 ppm to about 120 ppm, from about 40 ppm to about 50 ppm, from about 40 ppm to about 60 ppm, from about 40 ppm to about 70 ppm, from about 40 ppm to about 80 ppm, from about 40 ppm to about 90 ppm, from about 40 ppm to about 100 ppm, from about 40 ppm to about 110 ppm, from about 40 ppm to about 120 ppm, from about 50 ppm to about 60 ppm, from about 50 ppm to about 70 ppm , from about 50 ppm to about 80 ppm, from about 50 ppm to about 90 ppm, from about 50 ppm to about 100 ppm, from about 50 ppm to about 110 ppm, from about 50 ppm to about 120 ppm, from about 60 ppm to about 70 ppm, from about 60 ppm to about 80 ppm, from about 60 ppm to about 90 ppm, from about 60 ppm to about 100 ppm, from about 60 ppm to about 110 ppm, from about 60 ppm to about 120 ppm, from about 70 ppm to about 80 ppm, from about 70 ppm to about 90 ppm, from about 70 ppm to about 100 ppm, from about 70 ppm to about 110 ppm, from about 70 ppm to about 120 ppm, from about 80 ppm to about 90 ppm, from about 80 ppm to about 100 ppm, from about 80 ppm to about 110 ppm, from about 80 ppm to about 120 ppm, from about 90 ppm to about 100 ppm, from about 90 ppm to about 110 ppm, from about 90 ppm to about 120 ppm, about 100 ppm to about 110 ppm, about 100 ppm to about 120 ppm, or about 110 ppm to about 120 ppm.

Examples

The following non-limiting examples are provided for illustrative purposes only to facilitate a more complete understanding of the contemplated exemplary embodiments. These examples should not be considered limiting to any of the embodiments described in the present invention, including embodiments that relate to the compositions, kits, methods and uses described in the present invention.

Example 1. Compositions.

This example illustrates a method for preparing the composition described in the present invention. The components listed below were mixed at ambient temperature using a high shear mixer until a homogeneous mixture was obtained. The pH of the mixture was adjusted as shown.

Table 1

Compositions

Component F72 F73 F74 F75 F76 F77 Hypochlorous acid/F AC ^C 273 ppm 273 ppm 273 ppm 273 ppm 273 ppm 273 ppm Titanium dioxide particles — — 50 ppm 100 ppm — — Zinc oxide particles 50 ppm 100 ppm — — — — DTSACl ^a — — — — 100 ppm 200 ppm Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 5.5 6.3 4.1 3.9 3.9 3.6 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

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Compositions

table 2

Component F78 F79 F80 F81 F82 F83 Hypochlorous acid/F AC ^C 273 rrsh 273 rrsh 273 rrsh — — — Copper oxide particles 200 rrsh 300 rrsh — — — — DTSACl ^a — — 300 rrsh 1% 5% 1% Isopropanol — — — 50% 50% 98% Methanol — — — 2% 6% 1% Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 4.8 5.3 3.4 5.5 5.1 6.6 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient amount ^with FAC: - free active chlorine

Compositions

Table 3

Component F84 F85 F86 F87 F88 F89 Hypochlorous acid/F AC ^C 273 rrsh 273 rrsh 273 rrsh 273 rrsh — 530 ppm Titanium dioxide particles — — — 200 rrsh — — DTSACl ^a — — — — 5% — Copper(I) chloride — 300 rrsh — — — — Copper(II) chloride — — 300 rrsh — — — Zinc chloride 300 rrsh — — — — — Silver nitrate — — — — — 300 ppm Isopropanol — — — — 88.4% — Methanol — — — — 6.6% — Water q.s? q.s. q.s. q.s. q.s. q.s. pH 3.9 4.4 3.9 3.6 6.4 3.7 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

Compositions

Table 4

Component F90 F91 F92 F93 F94 F95A Hypochlorous acid/F AC ^C 530 ppm 530 ppm — 530 ppm 530 ppm 530 ppm Iron oxide particles — 300 ppm — — — — Titanium dioxide particles 100 ppm — — — — — DTSACl ^a — — — — — 500 ppm Didodecyldimethylammonium chloride — — 10% 300 ppm 300 ppm — Silver nitrate 200 ppm — — — — — Isopropanol — — 50% — — — Water q.s? q.s. q.s. q.s. q.s. q.s. pH 3.5 3.8 8.4 3.7 3.5 3.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride in 58% methanol or water ^b qs: - sufficient quantity ^with FAC: - free active chlorine

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Table 5

Compositions

Component F96 F100 F101 F102 F103 F104 Hypochlorous acid/F AC ^C 107 ppm 530 ppm 530 ppm 530 ppm — — Silver oxide particles — — — 200 ppm — — Zinc oxide particles — — — 200 ppm — — DTSACl ^a 100 ppm — — — — 5% Didodecyldimethylammonium chloride — — — — 5% — Copper(II) chloride — 500 ppm — — — — Potassium chloride — — 4000 ppm — — — Polyhexamethylene biguanide — — — — 10% 10% Isopropanol — — — — 45% 45% Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 3.7 3.4 3.7 6.4 8.3 6.8 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride in 58% methanol ^b qs: - sufficient amount ^with FAC: - free active chlorine

Table 6

Compositions

Component F105 F106 F107 F108 F109 F110 Hypochlorous acid/F AC ^C — — 530 ppm 530 ppm 530 ppm 530 ppm DTSACl ^a 4% — — — — 1000 ppm Didodecyldimethylammonium chloride — 4% — — — — Potassium chloride — — 600 ppm 600 ppm 600 ppm — Potassium phosphate — — 6000 ppm 2000 ppm 2000 ppm — Polyhexamethylene biguanide 6% 6% — — — — Isopropanol 50% 50% — — — — Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 6.6 8.5 H.9 7.7 8.9 4.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride in 58% methanol ^b qs: - sufficient amount ^with FAC: - free active chlorine

Table 7

Compositions

Component F112 F115 F116 F117 F118 F119 Hypochlorous acid/F AC ^C — — — 281 ppm 530 ppm 1933 ppm Chlorhexidine 0.06% 0.12% — — — — DTSACl ^a — — — — — 2000 ppm Zinc acetate — — 0.14% 300 ppm 600 ppm — Polyhexamethylene biguanide 0.06% — 0.12% — — — Ethanol 15% 15% 15% — — — Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 7.6 7.3 6.9 5.4 5.4 3.7 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

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Table 8

Compositions

Component F120 F121 F122 F123 F124 F125 Hypochlorous acid/PAC ^with 105 ppm 105 ppm 500 ppm 281 ppm 281 ppm 530 ppm Titanium dioxide particles — — — — — — Mixed copper, zinc and iron oxide particles — — — 300 ppm — — DTSACl ^a — — — — 300 ppm 500 ppm Potassium chloride 600 ppm 120 ppm — — — — Potassium phosphate 2000 ppm 400 ppm — — — — Silver nitrate — — — — 300 ppm 500 ppm Zinc sulfate — — 600 ppm — — — Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 7.0 7.6 3.7 5.2 3.5 3.5 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

Table 9

Compositions

Component F126 F127 F128 F129 F130 F131 Hypochlorous acid/PAC ^with 281 ppm 530 ppm 600 ppm 278 ppm 1933 ppm 600 ppm Titanium dioxide particles 100 ppm 100 ppm — — — — DTSACl ^a Silver nitrate Poly(acrylic acid) Water 300 ppm 200 ppm qs ^b 500 ppm 300 ppm q.s. 45% q.s. 2% q.s. 2% q.s. 2% q.s. pH 3.7 3.5 2.9 2.8 2.9 7.3 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride in 58 ⁽ methanol ^b qs: - sufficient amount ^with FAC: - free active chlorine /O

Table 10

Compositions

Component F132 F133 F134 F135 F138 F139 Hypochlorous acid/F AC ^C 600 ppm 600 ppm 1933 ppm 600 ppm 600 ppm 600 ppm DTSACl ^a — — 600 ppm — 600 ppm 1200 ppm Silver nitrate 600 ppm — — — — — Zinc sulfate — 600 ppm — — — — Polyhexamethylene biguanide — — — — 600 ppm 1200 ppm Poly(acrylic acid) 2% 2% 2% — — — Cetylpyridinium chloride — — — 600 ppm — — Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 2.7 2.9 2.9 4.0 3.0 3.0 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride in 58 ^{methanol b} qs: - sufficient amount ^with FAC: - free active chlorine /O

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Table 11

Compositions

Component F140 F141 F142 F143 F144 F145 Hypochlorous acid/F AC ^d 600 ppm 600 ppm 600 ppm 500 ppm 500 ppm 500 ppm Mixed copper, zinc and iron oxide particles — — — 600 ppm 300 ppm — DTSACl ^a — 600 ppm 1200 ppm 600 ppm — — TTSACl ^b — — — — — 500 ppm Polyhexamethylene biguanide — — — — — — Opmo-phthalaldehyde 600 ppm 600 ppm 1200 ppm — — — Water qs ^c q.s. q.s. q.s. q.s. q.s. pH 2.6 3.4 3.2 5.2 5.0 3.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b TTSAC1: tetradecyldimethyl-(3-trimethoxysilyl)propylammonium chloride in water ^c qs: - sufficient quantity ^d FAC: - free active chlorine

Table 12

Compositions

Component F146 F147 F148 F149 F150 F151A Hypochlorous acid/F AC ^C 2200 ppm 500 ppm 500 ppm 500 ppm 500 ppm 500 ppm Mixed copper, zinc and iron oxide particles 300 ppm — — — — 250 ppm DTSACl ^a — 250 ppm 125 ppm 50 ppm 25 ppm — Water qs ^b q.s. q.s. q.s. q.s. q.s. rn 4.6 3.6 3.7 3.7 3.6 4.7 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

Table 13

Compositions

Component F152 F153 F154 F155 F156 F157 Hypochlorous acid/F AC ^C 500 ppm 500 ppm 500 ppm 500 ppm 500 ppm — Mixed copper, zinc and iron oxide particles 200 ppm 150 ppm 100 ppm 50 ppm 25 ppm — DTSACl ^a — — — — — 10% Isopropanol — — — — — 50% Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 4.3 3.8 3.2 3.8 3.7 4.6 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

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Compositions

Table 14

Component F158 F163 F168 F169 F170 F171 DTSACl ^a — 20% 10% — — — Didodecyldimethylammonium chloride 5% — — — — — Polyhexamethylene biguanide 5% — — — — — Isopropanol 5% — 50% — — 5% Methanol — 7% — 50% — — TRITON CG-110 3% — — — — — Poloxamer 407 — — — — 2% — Quatemium-18 — — — 6% 10% 10% Water qs ^b q.s. q.s. q.s. q.s. q.s. pH BUT 6.4 BUT BUT BUT BUT ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity

Compositions

Table 15

Component F172 F173 F177 F178 F179 F180 Hypochlorous acid/PAC ^with — — 540 ppm DTSACl ^a 500 rrsh 20% — — — — Di-n-alkyldimethylammonium chloride — — 500 ppm — — — Didodecyldimethylammonium chloride — — — 500 ppm — — Methanol — 7% — — — — Copper(II) chloride — — — — — 200 ppm Ferric(II) chloride or ferric(III) chloride — — — — — 200 ppm Silver nitrate — — — — 500 ppm — Zinc acetate — — — — 500 ppm — Zinc chloride — — — — 200 ppm Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 5.4 6.4 7.6 6.2 6.9 2.6 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

Compositions

Table 16

Component F181 F182 F183 F184 F185 F186 Hypochlorous acid/F AC ^C 540 ppm 540 ppm 540 ppm 540 ppm 540 ppm 540 ppm DTSACl ^a — 500 ppm 500 ppm 500 ppm 500 ppm 500 ppm Copper(II) chloride 200 ppm — — — — — Ferric(II) chloride or ferric(III) chloride 200 ppm — — — — — Zinc chloride 200 ppm — — — — — Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 2.4 5.9 5.4 6.0 5.1 6.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

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Table 17

Compositions

Component F187 F188 F189 F190 F191 F192 Hypochlorous acid/FAC 540 ppm 350 ppm 350 ppm 260 ppm 260 ppm 190 ppm DTSACl ^a 300 ppm 500 ppm 300 ppm 500 ppm 300 ppm 500 ppm Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 5.5 5.7 5.5 5.2 5.4 5.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride at 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine Table 18 Compositions Component F193 F194 F195 F95B F95C F95D Hypochlorous acid/F AC ^d 190 ppm 100 ppm 100 ppm 530 ppm 75 ppm 75 ppm DTSACl ^a 300 ppm 500 ppm 300 ppm — 300 ppm 500 ppm DTSACl ^b — — — 530 ppm — — Water qs ^c q.s. q.s. q.s. q.s. q.s. pH 5.5 5.8 5.4 3.2 5.8 5.4

^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b DTSAC1: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in water ^c qs: - sufficient quantity ^d FAC: - free active chlorine

Compositions

Table 19

Component F95E F95F F95G F95H F95I F95J Hypochlorous acid/F AC ^C 50 ppm 50 ppm 40 ppm 40 ppm 35 ppm 35 ppm DTSACl ^a 500 ppm 300 ppm 500 ppm 300 ppm 500 ppm 300 ppm Water qs ^b q.s. q.s. q.s. q.s. q.s. pH 5.8 5.4 5.8 5.4 5.8 5.4 ^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine Component Hypochlorous acid/F AC ^C DTSACl ^a Water pH Composition F95K 25 ppm 500 ppm qs ^b 5.8 in you composition F95L 25 ppm 300 ppm q.s. 5.4 tions F95M 10 ppm 500 ppm q.s. 5.8 F95N 10 ppm 300 ppm q.s. 5.4 T. F95O 5 ppm 500 ppm q.s. 5.8 table 20 F95P 5 ppm 300 ppm q.s. 5.4

^a DTSACl: dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride in 58% methanol ^b qs: - sufficient quantity ^with FAC: - free active chlorine

Compositions

Table 21

Component F151B F151C F151D F151E F151F F151G Hypochlorous acid/F AC ^C 350 ppm 260 ppm 190 ppm 100 ppm 75 ppm 50 ppm Mixed Oxide Particles 250 ppm 250 ppm 250 ppm 250 ppm 250 ppm 250 ppm

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copper, zinc and iron Water qs ^a q.s. q.s. q.s. q.s. q.s. pH 4.7 4.7 4.7 4.7 4.7 4.7 ^a qs: - sufficient amount ^b FAC: - free active chlorine

Table 22

Compositions

Component F151H F151I F151J F151K F151L F180A Hypochlorous acid/F AC ^C 40 ppm 35 ppm 25 ppm 10 ppm 5 ppm 350 ppm Mixed copper, zinc and iron oxide particles 250 ppm 250 ppm 250 ppm 250 ppm 250 ppm — Copper(II) chloride — — — — — 200 ppm Ferric(II) chloride or ferric(III) chloride — — — — — 200 ppm Zinc chloride — — — — — 200 ppm Water qs ^a q.s. q.s. q.s. q.s. q.s. pH 4.7 4.7 4.7 4.7 4.7 2.6 ^a qs: - sufficient amount ^b FAC: - free active chlorine Table 23 Compositions Component F180B F180C F180D F180E F180F F180G Hypochlorous acid/F AC ^C 260 ppm 190 ppm 100 ppm 75 ppm 50 ppm 40 ppm Copper(II) chloride — — 200 ppm 200 ppm 200 ppm 200 ppm Ferric(II) chloride or ferric(III) chloride 200 ppm 200 ppm 200 ppm 200 ppm 200 ppm 200 ppm Zinc chloride 200 ppm 200 ppm 200 ppm 200 ppm 200 ppm 200 ppm Water 200 ppm 200 ppm q.s. q.s. q.s. q.s. pH qs ^a q.s. 2.6 2.6 2.6 2.6 2.6 2.6

qs: - sufficient quantity ^b FAC: - free active chlorine

Table 24

Compositions

Component F180H F180I F180J F180K Hypochlorous acid/F AC ^C 35 ppm 25 ppm 10 ppm 5 ppm Copper(II) chloride 200 ppm 200 ppm 200 ppm 200 ppm Ferric(II) chloride or ferric(III) chloride 200 ppm 200 ppm 200 ppm 200 ppm Zinc chloride 200 ppm 200 ppm 200 ppm 200 ppm Water qs ^a q.s. q.s. q.s. pH 2.6 2.6 2.6 2.6 ^a qs: - sufficient amount ^b FAC: - free active chlorine

Example 2: Spore viability assays.

This example illustrates how to perform a spore viability assay using the composition described in the present invention.

To prepare pathogenic spore stock cultures, 10 ml of nutrient broth was inoculated using a Bacillus subtilis stock culture (ATCC #19659) and incubated on an orbital shaker for 24 ± 2 h at approximately 150 rpm at 36 ± 1°C. This culture was used to inoculate Tryptic Soy Agar (TSA) plates. Each plate was inoculated with 500 μl of broth culture and the inoculum was distributed with a sterile L-shaped spreader. In addition, the purity of the specified culture was confirmed by streaking plates with TSA and incubating the plates at 36±1°C for 24±2 hours. Each plate was wrapped in parafilm, inverted and incubated for 12-14 days at 36±1°C . After incubation, spores were collected by adding 10 ml of cold sterile water to each dish, the grown culture was removed from the dishes using a spreader.

- 88 043933 calves and the resulting suspensions were transferred into sterile 15 ml conical tubes. The suspensions were centrifuged at 5000 rpm (4500xg) for approximately 10 min at room temperature. After removal of the supernatant, the spore pellet was washed by resuspending the pellet in 10 ml of cold sterile water and centrifuged at 5000 rpm (4500xg) for approximately 10 min. This washing step was repeated two more times. The spore pellet was resuspended in 10 ml of sterile water and the spore suspension was stored at 2-5°C until use. The spore suspension was stained using a staining agent and the spores were examined under a microscope to evaluate the quality of the spores. At least five fields were examined and the ratio of spores to vegetative cells (or sporangia) was determined. The percentage of spores compared to vegetative cells was approximately 95% spores. Spore titer was determined by preparing serial dilutions, plating the dilutions on TSA plates, incubating the plates for 48 ± 2 h at 36 ± 1°C, and counting the number of colonies formed to determine the titer. The test culture was standardized using phosphate buffer to obtain a final microbial population of the test culture of 1.0 x 106 CFU/ml.

Samples for analysis were prepared with serum, such as tryptic soy broth (TSB) or bovine serum (BS), or without serum. The purpose of the serum was to better mimic the organic load in the blood and other tissues that tends to deactivate the antimicrobial agent. In general, assays are performed by first incubating a sample of pathogen spores with a composition described herein for a specified period of treatment, optionally with serum, followed by culturing the sample in a growth medium to measure bacterial colony formation and hence spore viability.

In one set of experiments, samples of compositions F72-F92 were serum treated to contain 100 μl of a pathogen spore suspension (containing approximately 1x10 ³ CFU/ml), 50 μl of serum and 850 μl of the composition described in example 1. In assays in which samples were not treated with serum, the samples contained 100 μl of a suspension of pathogen spores (containing approximately 1x103 CFU/ml) and 900 μl of the composition described in example 1. All samples were incubated for 15 minutes and then sown in Petri dishes containing TSA nutrient medium. The inoculated plates were then incubated at 30°C-35°C for 48 hours and the number of colonies, if present, was counted. It should be noted that when describing specific quantities and volumes, different quantities and volumes may be used. For example, the processed sample may contain 100 μl of a pathogen spore suspension (containing approximately 1 x 106 CFU/ml), 500 μl of serum and 9400 μl of the composition described in the present invention. The raw sample may contain 100 μl of a pathogen spore suspension (containing approximately 1 x 103 CFU/ml) and 9900 μl of the composition described in the present invention. The results of this series of experiments are presented in table. 25.

In another series of experiments, samples of compositions F103-F106, F112, F115, F116, F138, F139 and F157 were treated with serum to contain 100 μl of a suspension of pathogen spores (containing approximately 1x106 CFU/ml), 50 μl of serum and 850 μl of the composition described in Example 1. In assays in which samples were not treated with serum, samples contained 100 μl of a pathogen spore suspension (containing approximately 1x106 CFU/ml) and 900 μl of the composition described in example 1. All samples were incubated for 30 min, 6 times serially diluted 1:10 using DiE broth (DE) and then inoculated into Petri dishes containing TSA nutrient medium. The inoculated plates were then incubated at 30°C-35°C for 48 hours and the number of colonies, if present, was counted. It should be noted that when describing specific quantities and volumes, different quantities and volumes may be used. For example, the processed sample may contain 100 μl of a pathogen spore suspension (containing approximately 1 x 106 CFU/ml), 500 μl of serum and 9400 μl of the composition described in the present invention. The raw sample may contain 100 μl of a pathogen spore suspension (containing approximately 1 x 106 CFU/ml) and 9900 μl of the composition described in the present invention. The results of this series of experiments are presented in table. 26.

The results indicate that at least compositions F81, F82, F83, F88 and F92 demonstrate greater potential as a disinfectant for the applications described in the present invention.

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Table 25

Spore viability analysis_______________________

Compound Number of colonies ^{a, b, c} 0% whey 2.5% whey 5% whey F81 0 0 0 F82 0 0 0 F83 0 0 0 F88 0 0 0 F92 0 0 0 ^a Values designated as >500 indicate that there were too many bacterial colonies to count, so a score of greater than 500 was assigned. ^b Positive controls for all assays performed were >500 bacterial colonies ^with H/O, not determined.

Table 26

Spore viability analysis

Compound Log growth reduction ^{a, b, c} 0% whey 2.5% whey 5% whey F103 BUT BUT BUT F104 BUT BUT BUT F105 BUT BUT BUT F106 BUT BUT BUT F112 BUT BUT BUT F115 BUT BUT BUT F116 BUT BUT BUT F138 BUT BUT BUT F139 BUT BUT BUT F157 BUT BUT >1.7 log

^a A minimum reduction of 3 orders of magnitude in bacterial growth represents >99.9% bacterial kill ^b Positive controls for all assays performed showed a 0 log reduction in bacterial growth ^with H/O, not determined

Similar spore viability assays can be performed as described above, except that the pathogen being assessed will be Escherichia coli and Pseudomonas species.

Example 3: Bacterial Viability Assays.

This example illustrates how to perform a bacterial viability assay using the composition described in the present invention.

To prepare stock cultures of pathogenic bacteria, 10 ml of nutrient broth was inoculated with Staphylococcus epidermidis stock culture (ATCC 12228) and incubated on an orbital shaker for 24 ± 2 h at approximately 150 rpm at 36 ± 1°C. This culture was used to inoculate Tryptic Soy Agar (TSA) plates. Each plate was inoculated with a culture. Each plate was incubated for up to 5 days at 30°C-35°C. After incubation, suspensions were prepared by adding the grown cultures from the TSA plates to a tube containing sterile water. Each tube was then vortexed and an aliquot was serially diluted and plated onto a TSA plate for further counting. The aliquot volume, the amount obtained on the TSA plate, and the total initial culture volume were used for the final count. The remaining amount in the tube was used to inoculate the actual test samples.

Samples of each of the test compositions were prepared with serum (TSB or bovine serum) or without serum as follows: 1) serum assays contained 100 μl of a suspension of pathogenic bacteria, 500 μl of serum and 9400 μl of the composition described in the present invention; and 2) serum-free assays contained 100 μl of a pathogenic bacterial suspension and 9900 μl of the composition described in Example 1. The samples were incubated for 5 minutes, after which a neutralizing agent was applied to inhibit the activity of the microbial agent being tested. In the case of compositions F72-F80, F84-F87, F89-F91, F93, F94, F96 and F100-F102, the treated sample was sown in Petri dishes containing TSA nutrient medium and incubated at 30°C-35°C for up to 5 days . The presence of viable bacteria was then measured by counting the number of colonies observed in the agar medium. The results of this series of experiments are presented in table. 27.

In the case of compositions F95, F107-F110, F117-F135, F140-F156 and F163, the treated samples were serially diluted 6 times 1:10 after treatment with a neutralizing agent and the treated sample was plated in

- 90 043933 Petri dishes containing TSA nutrient medium and incubated at 30°C-35°C for up to 5 days.

The presence of viable bacteria was then measured by counting the number of colonies observed in the agar medium. The results of this series of experiments are presented in table. 28.

The results indicate that at least compositions F80, F81, F82, F83, F88, F89, F90, F92, F93, F94, F95, F102, F144, F145, F146, F147, F148, F149, F150, F151, F152, F153, F154, F155 and F156 show greater potential as a disinfectant for the applications described in the present invention.

Table 27

Bacterial viability assay

Compound Number of colonies ^{a, b, c} 0% whey 2.5% whey 5% whey F72 0 205 225 F73 0 204 209 F74 0 156 205 F75 0 200 190 F76 0 152 105 F77 0 70 69 F78 0 190 223 F79 0 185 140 F80 0 0 0 F81 0 0 0 F82 0 0 0 F83 0 0 0 F84 0 232 225 F85 0 260 206 F86 0 205 180 F87 0 180 165 F88 0 0 0 F89 0 6 21 F90 0 3 15 F91 0 302 220 F93 0 0 0 F94 0 0 0 F96 0 >500 >500 F100 0 >500 >500 F101 0 >500 >500 F102 0 10 100

^a Values designated as >500 indicate that there were too many bacterial colonies to count, so a score of greater than 500 was assigned. ^b Positive controls for all assays performed were >500 bacterial colonies ^with H/O, not determined.

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Table 28

Bacterial viability assay

Compound Log growth reduction ^{a, b, c} 0% whey 2.5% whey 5% whey F95 >7.2 log >7.1 log >6.8 log F107 BUT BUT BUT F108 But But But F109 BUT But But F110 But But <6.0 log F117 But But But F118 But But But F119 But But 6 log F120 But But But F121 But But But F122 But But But F123 But But <6.0 log F124 But But But F125 But But But F126 But But But F127 But But But F128 But But But F129 But But But F130 But But But F131 But But But F132 But But But F133 But But But F134 But But But F135 But But But F140 But But But

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F141 BUT BUT BUT F142 BUT BUT BUT F143 BUT BUT BUT F144 BUT BUT >6.8 log F145 BUT BUT >7.4 log F146 BUT BUT >7.3 log F147 BUT BUT >7.4 log F148 BUT BUT <6.0 log F149 BUT BUT <6.0 log F150 BUT BUT <6.0 log F151 >7.2 log >7.1 log >7.2 log F152 BUT BUT >6.2 log F153 BUT BUT <6.0 log F154 BUT BUT <6.0 log F155 BUT BUT >7.1 log F156 BUT BUT >7.6 log F157 BUT BUT >7.1 log F163 BUT BUT H/O F168 BUT BUT H/O F169 BUT BUT H/O F170 BUT BUT H/O F171 BUT BUT H/O F172 BUT BUT <6.0 log F173 BUT BUT <6.0 log F177 BUT BUT <6.0 log F178 BUT BUT >7.0 log F179 BUT BUT <6.0 log F180 BUT BUT >7.1 log F181 BUT BUT >7.1 log F182 BUT BUT <6.0 log F183 BUT BUT <6.0 log F184 BUT BUT <6.0 log F185 BUT BUT <6.0 log F186 BUT BUT <6.0 log F187 BUT BUT H/O F188 BUT BUT H/O F189 BUT BUT H/O F190 BUT BUT H/O F191 BUT BUT H/O F192 BUT BUT H/O F193 BUT BUT H/O F194 BUT BUT H/O F195 BUT BUT H/O ^a A minimum reduction of 3 orders of magnitude in bacterial growth represents >99.9% bacterial kill ^b Positive controls for all assays performed showed a 0 log reduction bacterial growth ^with H/O, not determined

Example 4: Bacterial Viability Assays.

This example illustrates how to perform a bacterial viability assay using the composition described in the present invention.

Stock cultures of the pathogenic bacteria Staphylococcus epidermidis (ATCC 12228) were prepared as described in Example 3. The aliquot volume, the amount obtained on the TSA plate, and the total original culture volume were used for the final count. The remaining amount in the tube was used to inoculate the actual test samples.

Samples of each of the tested compositions were prepared with bovine serum as follows: 1) serum tests contained 100 μl of a suspension of pathogenic bacteria, 500 μl of bovine serum and 9400 μl of one of the compositions presented in table 29; 2) HOC1 control assays contained 100 μl of a suspension of pathogenic bacteria, 500 μl of bovine serum and 9400 μl of 350 ppm, 200 ppm,

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100 ppm or 50 ppm hypochlorous acid; 3) salt control assays contained 100 μl of a pathogenic bacterial suspension, 500 μl of bovine serum, and 9400 μl of 140 ppm, 80 ppm, 40 ppm, or 20 ppm each of copper(II) chloride, ferric chloride, and zinc chloride or each of chloride copper(II), iron(III) chloride and zinc chloride; and 4) negative control assays contained 100 μl of pathogenic bacterial suspension, 500 μl of bovine serum, and 9400 μl of sterile water. The samples were held for five (5) minutes, after which a neutralizing agent was applied to inhibit the activity of the microbial agent being tested. The compositions were sown in Petri dishes containing TSA nutrient medium and incubated at 30°C-35°C for up to 5 days. The presence of viable bacteria was then measured by counting the number of colonies observed in the agar medium. The results of this series of experiments are presented in table. thirty.

Table 29

Compositions

Component F196 F197 F198 F199 F200 F201 F202 F203 Hypochlorous acid/FAC 350 ppm 200 ppm 100 PPm 50 ppm 350 ppm 200 PPm 100 PPm 50 ppm Copper(II) chloride 140 ppm 80 ppm 40 ppm 20 ppm 140 ppm 80 ppm 40 ppm 20 ppm Iron(II) chloride 140 ppm 80 ppm 40 ppm 20 ppm — — — — Iron(III) chloride — — — — 140 ppm 80 ppm 40 ppm 20 ppm Zinc chloride 140 ppm 80 ppm 40 ppm 20 ppm 140 ppm 80 ppm 40 ppm 20 ppm Water q.s. q.s. q.s. q.s. q.s. q.s. q.s. q.s. pH 3.2 3.6 3.7 4.0 3.0 3.2 3.6 3.7

The results show that the compositions containing iron (III) chloride showed a synergistic effect in reducing bacterial growth compared to controls. For example, F200 and F201 exhibit more than a two-fold reduction in bacterial growth compared to hypochlorous acid controls in the applications described herein. Mixtures of the metal salts, zinc chloride, iron (II) chloride and copper chloride or zinc chloride, iron (III) chloride and copper chloride, do not demonstrate any detectable antimicrobial activity in these assays. Another important finding is that F2020 showed an equivalent reduction in bacterial growth compared to the HOC1 control containing 200 ppm hypochlorous acid. F202 contains only 100 ppm hypochlorous acid, and this 50% reduction is critical to provide increased hypochlorous acid stability.

Table 30

Bacterial viability assay

Compound Log growth reduction ^{a, b, c} Compound NOS1 control Salt control' ¹ F196 4.19 4.47 0 F197 1.72 3.00 0 F198 2.18 2.24 0 F199 1.87 1.41 0 F200 6.65 3.18 0 F201 6.65 3.03 0 F202 2.71 2.77 0 F203 1.62 0.77 0 ^a A minimum reduction of 3 orders of magnitude in bacterial growth represents >99.9% bacterial kill ^b Positive controls for all assays performed showed a 0 log reduction in bacterial growth ^with HOC1 control matched the concentration of hypochlorous acid present in the formulation ^d Metal salt control matched the metal salt concentration , present in the composition

In another series of experiments, the COL1 and COL2 formulations were compared with six commercial products containing only HOC1 (Table 31). In this series of experiments, samples of each of the test compositions were prepared with bovine serum as follows: 1) serum tests contained 100 μl of a suspension of pathogenic bacteria, 500 μl of bovine serum and 9400 μl of one of the compositions, as shown in table. 31; 2) positive HOC1 control assays contained 100 μl of pathogenic bacteria suspension and 9900 μl of sterile water. Samples were allowed to stand for one (1) minute, after which a neutralizing agent was applied to inhibit the activity of the test substance.

-94043933 microbial agent. The compositions were sown in Petri dishes containing TSA nutrient medium and incubated at 30°C-35°C for up to 5 days. The presence of viable bacteria was then measured by counting the number of colonies observed in the agar medium. The results of this series of experiments are presented in table. 31.

The results indicate that the COL1 and COL2 compositions exhibit equal or greater potential than commercially available cleaners and disinfectants with equal or greater levels of hypochlorous acid in the applications described in the present invention. Specifically, COL1, which contained 40 ppm hypochlorous acid and 1000 ppm DTSACl, showed more than a 3-fold reduction in bacterial growth compared to commercial product 6, which contains only 40 ppm hypochlorous acid. Likewise, COL2, which contained 90 ppm hypochlorous acid and 500 ppm DTSACl, showed more than a 2-fold reduction in bacterial growth compared to commercial product 3, which contained only 104 ppm hypochlorous acid. The synergistic activity observed in COL1 and COL2 is attributed to the presence of DTSACl in these formulations.

Table 31

Bacterial viability assay

Compound Log growth reduction ^a,b COL1 (40 ppm HOC1 and 1000 ppm DTSACl) 3.6 COL2 (99 ppm HOC1 and 500 ppm DTSACl) 2.3 Commercial Product 1 (68 ppm HOC1) 1.1 Commercial Product 2 (104 ppm HOC1) 1.0 Commercial Product 3(110 ppm HOC1) 2.0 Commercial Product 4 (154 ppm HOC1) 1.2 Commercial Product 5 (223 ppm HOG) 2.3 Commercial Product 6 (270 ppm HOC!) 3.0 ^a A minimum reduction of 3 orders of magnitude in bacterial growth represents eradication >99.9% bacteria ^b Positive controls for all assays performed showed a 0 log reduction bacterial growth

Finally, it should be understood that although aspects of the present invention are illustrated with reference to specific embodiments, one skilled in the art will readily understand that these described embodiments are only illustrative of the principles of the subject matter described herein. Therefore, it should be understood that the described subject matter is not limited to any extent to the specific compound, composition, article, apparatus, methodology, protocol and/or reagent, etc. described in the present invention, unless expressly stated otherwise. Moreover, those skilled in the art will appreciate that certain changes, modifications, permutations, corrections, additions, deletions, and subcombinations thereof may be made in accordance with the teachings presented in the present invention without departing from the spirit of the present invention. Accordingly, the following claims and claims that may be added after filing are intended to be interpreted to include all such changes, modifications, permutations, corrections, additions, deletions and subcombinations as fall within their actual spirit and scope. .

The present invention describes some embodiments according to the present invention, including the best method known to the inventors of the present invention for implementing the present invention. Of course, changes in these described embodiments will be apparent to those skilled in the art upon reading the above description. The present inventors expect that those skilled in the art will make such modifications as necessary, and the present inventors believe that the present invention may be practiced in a manner other than those specifically described in the present invention. Accordingly, the present invention includes all modifications and equivalents of the subject matter set forth in the appended claims, within the limits of applicable law. In addition, the present invention covers any combination of the above-described embodiments in all possible embodiments, unless otherwise indicated in the present invention or the context clearly indicates otherwise.

The groupings of alternative embodiments, elements or steps according to the present invention should not be construed as limitations. Each group member may be mentioned and claimed individually or in any combination with other group members described in the present invention. It is believed that one or more members of the group may be included or excluded from the group for reasons of convenience and/or patentability. When implementing such

- 95 043933 inclusions or deletions are considered to include the modified group, thus fully complying with the description of all Markush groups used in the claims of the attached claims.

Unless otherwise indicated, all numbers expressing a characteristic, object, quantity, parameter, property, term, etc., used in the present invention and claims are to be understood as modified in all cases by the term about. As used herein, the term roughly means that the characteristic, item, quantity, parameter, property or term so qualified covers a range of plus/minus ten percent above or below the value of the specified characteristic, subject, quantity, parameter, property or term. Accordingly, unless otherwise indicated, figures set forth in the specification and claims are approximate values that may vary. For example, since mass spectrometry instruments may vary slightly in determining the mass of a given analyte, the term roughly in the context of ion mass or ion mass/charge ratio refers to ±0.50 atomic mass unit. At the very least, and not as an attempt to limit the application of the doctrine of equivalents to the scope of the claims, each numerical indication should be considered at least in terms of the number of significant figures given and using normal rounding techniques.

The use of the terms can or able when applied to an embodiment or aspect of an implementation option also includes the alternative meaning can't or can't. As such, if the present invention describes that an embodiment or aspect of an embodiment may or is capable of being included as part of the subject matter of the present invention, then a negative limitation or exclusionary condition is also expressly implied to mean that the embodiment or aspect of an embodiment may not be included or not capable of being included as part of the subject matter of the present invention. Likewise, the use of a term optionally in relation to an embodiment or aspect of an embodiment means that such embodiment or aspect of an embodiment may or may not be included as part of the subject matter of the present invention. The applicability of such a negative limitation or exclusionary condition depends on whether the negative limitation or exclusionary condition is specified in the claimed subject matter.

Although numerical ranges and values representing the broad scope of the present invention are approximate, numerical ranges and values given in specific examples are stated as accurately as possible. However, any numerical range or value by definition includes certain errors that are necessarily the result of the standard deviation found in its respective test measurements. The present invention's listing of numeric value ranges is intended only as a shorthand way of providing individual references to each individual numeric value within the range. Unless otherwise specified in the present invention, each individual numerical range value is included herein as if it were separately identified in the present invention.

The singular number and similar references used in the context of the description of the present invention (especially in the context of the following claims) include the singular and plural forms, unless otherwise indicated in the present invention or the context clearly indicates otherwise. In addition, ordinal indices, such as first, second, third, etc., for identified elements are used to distinguish elements, and they do not indicate or imply a required or limited number of such elements or indicate a specific position or order of such elements, unless specifically stated otherwise. All methods described in the present invention can be carried out in any suitable order, unless otherwise indicated in the present invention or the context clearly indicates otherwise. The use of any and all examples or exemplary statements (eg, such as) presented in the present invention is intended only to better demonstrate the present invention and does not limit the scope of the present invention as otherwise claimed. Nothing in this specification should be taken to indicate any unclaimed element essential to the practice of the present invention.

When used in claims, whether in use at the time of filing or added in revisions, the open transitional term containing (and equivalent open transitional phrases, such as including, containing and having) covers all expressly stated elements, limitations , steps and/or features, alone or in combination with unspecified subject matter; provided that named elements, limitations and/or features are essential, and other unnamed elements, limitations and/or features may be added while remaining within the scope of the claims. Specific embodiments described in the present invention may be further limited in the claims by the use of closed transitions

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Claims (38)

phrases consisting of or consisting essentially of instead of or as a complement to the term containing. When used in claims, whether in use at the time of filing or added in revisions, a closed transition phrase consisting of excludes any element, limitation, step or feature not expressly stated in the claims. A closed transition phrase consisting essentially of limits the scope of the claims to the expressly stated elements, limitations, steps and/or features and any other elements, limitations, steps and/or features that do not materially affect the essential and novel characteristics of the claimed subject matter. . Thus, the meaning of the open transition phrase containing is defined to include all explicitly stated elements, limitations, steps and/or features, as well as any optional, additional, unspecified elements, limitations, steps and/or features. The meaning of the closed transition phrase consisting of is defined as including only the elements, limitations, steps and/or features expressly stated in the claims, while the meaning of the closed transition phrase consisting essentially of is defined as including only the elements, limitations, steps and/ or features expressly stated in the claims, and elements, limitations, steps and/or features that do not materially affect the essential and novel characteristics of the claimed subject matter. Thus, the open transition phrase containing (and its equivalent open transition phrases) includes within its meaning, as a limiting case, the claimed subject matter, defined by the closed transition phrases as consisting of or consisting essentially of. Therefore, such embodiments described in the present invention or claimed by the phrase consisting of are expressly or by definition unambiguously described, provided and supported in the present invention by the phrases consisting essentially of and consisting of. All patents, patent publications, and other publications set forth and identified herein are individually and expressly incorporated herein by reference in their entirety for the purpose of describing and disclosing, for example, the compositions and methodologies described in such publications as may be used in context of the present invention. Said publications are presented solely for their disclosure prior to the filing date of this application. Nothing in this regard should be construed as an admission that the inventors of the present invention are not entitled to precede such disclosure by virtue of prior invention or for any other reason. All statements as to the date or representations regarding the contents of the said documents are based on information available to the applicants and do not constitute any admission as to the correctness of the dates or the contents of the said documents. Finally, the terminology used in the present invention is intended only to describe specific embodiments and is not intended to limit the scope of the present invention, which is defined only by the claims. Accordingly, the present invention is not limited to the present description. CLAIM 1) from at least 50 ppm to not more than 500 ppm hypochlorous acid or from at least 50 ppm to not more than 500 ppm free active chlorine; 1) from at least 30 ppm to not more than 700 ppm hypochlorous acid or from at least 30 ppm to not more than 700 ppm free active chlorine; And 1. Disinfectant composition containing 2) from at least 150 ppm to no more than 900 ppm of one or more metal chloride salts, and where one or more metal chloride salts are copper chloride in an amount from 50 ppm to 300 ppm, iron (III) chloride in an amount from 50 ppm to 300 ppm and zinc chloride in amounts from 50 ppm to 300 ppm. 2. Disinfectant composition according to claim 1, characterized in that hypochlorous acid or free active chlorine is present in an amount from 30 ppm to 650 ppm. 2) one or more metal oxide particles, wherein one or more metal oxide particles are present in an amount of from 10 ppm to 300 ppm, or one or more metal salts, wherein one or more metal salts are present in an amount of at least 30 ppm up to not more than 900 ppm, where one or more metal oxide particles include copper, iron, titanium, zinc or any combination thereof, where one or more metal salts include a metal acetate, a metal chloride or a metal nitrate; and wherein the one or more metal salts include a copper salt in an amount of 10 ppm to 300 ppm, an iron salt in an amount of 10 ppm to 300 ppm, and a zinc salt in an amount of 10 ppm to 300 ppm. 3. Disinfectant composition according to claim 2, characterized in that hypochlorous acid or free active chlorine is present in an amount from 50 ppm to 600 ppm. 4. Disinfectant composition according to claim 3, characterized in that hypochlorous acid or free active chlorine is present in an amount from 100 ppm to 550 ppm. 5. Disinfectant composition according to claim 4, characterized in that hypochlorous acid or free active chlorine is present in an amount from 300 ppm to 500 ppm. 6. Disinfectant composition according to any one of claims 1 to 5, characterized in that one or more metal oxide particles are present in an amount from 50 ppm to 300 ppm or one or more metal salts are present in an amount from at least 50 ppm to no more 800 ppm. - 97 043933 7. The disinfectant composition of claim 6, wherein one or more metal oxide particles are present in an amount from 100 ppm to 300 ppm or one or more metal salts are present in an amount from at least 75 ppm to no more than 775 ppm. 8. The disinfectant composition of claim 7, wherein one or more metal oxide particles are present in an amount from 100 ppm to 275 ppm or one or more metal salts are present in an amount from at least 100 ppm to no more than 750 ppm. 9. The disinfectant composition of claim 8, wherein one or more metal oxide particles are present in an amount from 150 ppm to 250 ppm or one or more metal salts are present in an amount from at least 125 ppm to no more than 600 ppm. 10. The disinfectant composition according to any one of claims 1 to 9, characterized in that one or more metal oxide particles include copper oxide, iron oxide, titanium dioxide, zinc oxide, mixed oxide of copper, zinc and iron, or any combination thereof. 11. Disinfectant composition according to any one of claims 1 to 10, characterized in that one or more metal salts additionally include potassium, titanium. 12. The disinfectant composition according to any one of claims 1 to 11, characterized in that the one or more metal salts include a metal acetate, a metal chloride, a metal nitrate, a metal sulfate, or any combination thereof. 13. The disinfectant composition according to claim 12, wherein the metal chloride includes copper chloride, iron (II) chloride, iron (III) chloride and zinc chloride. 14. Disinfectant composition containing: 15. Disinfectant composition according to claim 14, characterized in that the disinfectant composition contains from 100 ppm to 450 ppm hypochlorous acid or from 100 ppm to 450 ppm free active chlorine and from 20 ppm to 200 ppm copper chloride, from 20 ppm to 200 ppm iron (III) chloride and from 20 ppm to 200 ppm zinc chloride. 16. Disinfectant composition according to any one of claims 1 to 15, further containing one or more carriers. 17. Disinfectant composition according to any one of claims 1 to 16, further containing one or more additional ingredients. 18. The disinfectant composition of claim 17, wherein the one or more additional ingredients include a preservative, a chelating agent, or any combination thereof. 19. A kit containing a composition according to any one of claims 1 to 18 and one or more delivery or application systems. 20. The kit according to claim 19, additionally containing instructions and/or container. 21. A method for cleaning, disinfecting and/or sterilizing a device, comprising applying a disinfectant composition according to any one of claims 1 to 18 to the device, wherein application of the composition cleans, disinfects and/or sterilizes the device. 22. Use of a disinfectant composition according to any one of claims 1 to 18 for cleaning, disinfecting and/or sterilizing a device. 23. A method for cleaning, disinfecting and/or sterilizing a surface area, comprising applying a disinfectant composition according to any one of claims 1 to 18 to a device, wherein application of the composition cleans, disinfects and/or sterilizes the device. 24. The method according to claim 23, wherein the surface region is a porous surface region or a non-porous surface region. 25. The method according to claim 23 or 24, wherein the surface area includes a table top, countertop, floor, wall, ceiling, window, door, door handle, shower, bathtub, sink, faucet, toilet, toilet seat, drain , equipment, machinery, personal protective equipment, personal biological protective equipment, medical device, dental device, pharmaceutical device, veterinary device, morgue device or human skin. 26. Use of a disinfectant composition according to any one of claims 1 to 18 for cleaning, disinfecting and/or sterilizing a surface area. 27. The use of claim 26, wherein the surface region is a porous surface region or a non-porous surface region. 28. The application of claim 26 or 27, wherein the surface area includes a table top, countertop, floor, wall, ceiling, window, door, door handle, shower, bathtub, sink, faucet, toilet, toilet seat, drain , equipment, machinery, personal protective equipment, personal biological protective equipment, medical device, dental device- - 98 043933 product, pharmaceutical device, veterinary device, mortuary device or human skin. 29. A method for cleaning, disinfecting and/or sterilizing a microbial infection in a patient, including applying a disinfectant composition according to any of the following. 1-18 per patient, wherein application of the composition cleanses, disinfects and/or sterilizes the patient. 30. The method according to claim 29, characterized in that the disinfectant composition is applied topically or administered enterally or parenterally. 31. Use of a disinfectant composition according to any of the following. 1-18 to clean, disinfect and/or sterilize a microbial infection in a patient. 32. Application according to claim 31, characterized in that the disinfectant composition is applied topically or administered enterally or parenterally. 33. A method of treating a condition in a patient, comprising applying a disinfectant composition according to any one of p. 1-18 per patient, wherein application of the composition results in treatment of a condition in the patient. 34. Method according to claim 33, characterized in that the disinfectant composition is applied topically or administered enterally or parenterally. 35. The method according to claim 33 or 34, characterized in that the condition is an ophthalmological condition, a dermatological condition, inflammation, aches or pain. 36. Use of a disinfectant composition according to any one of claims 1-18 for treating a condition in a patient. 37. Application according to claim 36, characterized in that the disinfectant composition is applied topically or administered enterally or parenterally. 38. The use of claim 36 or 37, wherein the condition is a wound, an ophthalmic condition, a dermatological condition, inflammation, aches or pain. Eurasian Patent Organization, EAPO Russia, 109012, Moscow, Maly Cherkassky lane, 2