EA031626B1 - Шприц-ручка с ограничителем последней дозы и улучшенными средствами для задания дозы - Google Patents
Шприц-ручка с ограничителем последней дозы и улучшенными средствами для задания дозы Download PDFInfo
- Publication number
- EA031626B1 EA031626B1 EA201691813A EA201691813A EA031626B1 EA 031626 B1 EA031626 B1 EA 031626B1 EA 201691813 A EA201691813 A EA 201691813A EA 201691813 A EA201691813 A EA 201691813A EA 031626 B1 EA031626 B1 EA 031626B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- dose
- cap
- setting
- tube
- cartridge
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 62
- 230000007246 mechanism Effects 0.000 claims abstract description 179
- 210000003813 thumb Anatomy 0.000 claims description 67
- 230000003993 interaction Effects 0.000 claims description 42
- 241000282472 Canis lupus familiaris Species 0.000 claims description 39
- 230000000903 blocking effect Effects 0.000 claims description 17
- 230000002093 peripheral effect Effects 0.000 claims description 13
- 230000003247 decreasing effect Effects 0.000 claims description 11
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 230000008859 change Effects 0.000 description 39
- 229940079593 drug Drugs 0.000 description 20
- 239000003814 drug Substances 0.000 description 20
- 238000002347 injection Methods 0.000 description 20
- 239000007924 injection Substances 0.000 description 20
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 20
- 230000006870 function Effects 0.000 description 12
- 102000004877 Insulin Human genes 0.000 description 9
- 108090001061 Insulin Proteins 0.000 description 9
- 229940125396 insulin Drugs 0.000 description 9
- 230000009471 action Effects 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 7
- 230000004913 activation Effects 0.000 description 5
- 238000013459 approach Methods 0.000 description 4
- 230000000295 complement effect Effects 0.000 description 4
- 210000003811 finger Anatomy 0.000 description 4
- 230000009467 reduction Effects 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 0 CCC(C1)CC2C1C*C=CC2 Chemical compound CCC(C1)CC2C1C*C=CC2 0.000 description 2
- 241000282465 Canis Species 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000002457 bidirectional effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 238000012377 drug delivery Methods 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- SAHNHMBHBZIHCK-UHFFFAOYSA-N C1C(CCCC2)SC3C2C13 Chemical compound C1C(CCCC2)SC3C2C13 SAHNHMBHBZIHCK-UHFFFAOYSA-N 0.000 description 1
- KBOOXGAGHTZHBI-LCVNCDSISA-N CC[C@@]12C(C)C(C)CC(C)[C@H]1C[C@@H]2C Chemical compound CC[C@@]12C(C)C(C)CC(C)[C@H]1C[C@@H]2C KBOOXGAGHTZHBI-LCVNCDSISA-N 0.000 description 1
- 241001343274 Dichrostachys spicata Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 238000009412 basement excavation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000008713 feedback mechanism Effects 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000004026 insulin derivative Substances 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pens And Brushes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1008MU2014 | 2014-03-25 | ||
| PCT/IB2015/051843 WO2015145294A1 (en) | 2014-03-25 | 2015-03-13 | Fluid delivery pen with final dose stop and improved dose setting features |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201691813A1 EA201691813A1 (ru) | 2017-03-31 |
| EA031626B1 true EA031626B1 (ru) | 2019-01-31 |
Family
ID=54194042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201691813A EA031626B1 (ru) | 2014-03-25 | 2015-03-13 | Шприц-ручка с ограничителем последней дозы и улучшенными средствами для задания дозы |
Country Status (20)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11872381B2 (en) | 2017-01-23 | 2024-01-16 | Sanofi | Drive train for dial of a torsion-spring assisted wind-up injection device |
| US10688247B2 (en) * | 2017-07-13 | 2020-06-23 | Haselmeier Ag | Injection device with flexible dose selection |
| JP7289297B2 (ja) * | 2017-12-04 | 2023-06-09 | ノボ・ノルデイスク・エー／エス | 撓み可能な変換器を有する薬剤注入デバイス |
| USD862690S1 (en) * | 2018-07-03 | 2019-10-08 | Haselmeier Ag | Medical injector |
| US11969583B2 (en) | 2018-07-17 | 2024-04-30 | Medmix Switzerland Ag | Injection device with dose interruption fail safe |
| CN109649044B (zh) * | 2018-12-27 | 2024-07-19 | 真彩文具股份有限公司 | 便于脱卸笔帽的笔结构 |
| WO2020169469A1 (en) * | 2019-02-19 | 2020-08-27 | Haselmeier Ag | Injection device with user friendly dose selector |
| RU2696451C1 (ru) * | 2019-03-27 | 2019-08-01 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Шприц-ручка для инъекций |
| RU2700459C1 (ru) * | 2019-04-03 | 2019-09-17 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Устройство для доставки лекарственного средства |
| RU2729432C1 (ru) * | 2019-10-23 | 2020-08-06 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Устройство для доставки лекарственного средства |
| EP4070832A1 (en) | 2021-04-07 | 2022-10-12 | medmix Switzerland AG | Keyed connectors |
| EP4434559A4 (en) * | 2021-11-15 | 2025-07-30 | Llc Next Bio | DRUG DELIVERY DEVICE |
| WO2023128820A1 (ru) * | 2021-12-29 | 2023-07-06 | Общество с ограниченной ответственностью "НЭКСТ БИО" | Устройство для доставки лекарственного средства |
| CN117138165B (zh) * | 2023-10-27 | 2024-01-23 | 江苏万海医疗器械有限公司 | 预制物料推送装置、输送器以及使用方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1681070A1 (en) * | 2005-01-18 | 2006-07-19 | Wockhardt Americas Inc. | Pen shaped medication injection devices |
| CH703993A2 (de) * | 2012-02-09 | 2012-03-15 | Tecpharma Licensing Ag | Injektionsgerät zur Verabreichung oder Förderung von fluidem Produkt. |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US703993A (en) * | 1902-03-07 | 1902-07-08 | Edward Carlson | Bolster. |
| DK175491D0 (da) | 1991-10-18 | 1991-10-18 | Novo Nordisk As | Apparat |
| BR9906857A (pt) * | 1998-01-30 | 2000-11-14 | Novo Nordisk As | Seringas de injeção |
| TR201903984T4 (tr) | 2003-08-12 | 2019-04-22 | Lilly Co Eli | Mekanik avantaja yönelik üçlü vida dişine sahip ilaç dağıtım aparatı. |
| EP1645301A1 (en) | 2004-10-11 | 2006-04-12 | Novo Nordisk A/S | Injection device |
| DE602005026595D1 (de) | 2004-12-01 | 2011-04-07 | Novo Nordisk As | Injektionsvorrichtung |
| CN101115520B (zh) | 2005-02-11 | 2010-04-21 | 诺和诺德公司 | 注射装置 |
| WO2006128794A2 (en) | 2005-05-31 | 2006-12-07 | Novo Nordisk A/S | Injection device with visual end-of-content indication |
| CN101227943B (zh) | 2005-07-27 | 2010-12-15 | 诺沃-诺迪斯克有限公司 | 用于限制对应于剩余药品量的剂量设定的注射设备的剂量机构 |
| JP5363119B2 (ja) * | 2006-01-24 | 2013-12-11 | ピュラック バイオケム ビー． ブイ． | ホモ乳酸的好熱性バチルスの遺伝子改変 |
| DE102006038103B4 (de) | 2006-08-14 | 2017-02-23 | Tecpharma Licensing Ag | Injektionsvorrichtung mit variabler Gewindeführung |
| DE102006038101A1 (de) | 2006-08-14 | 2008-02-21 | Tecpharma Licensing Ag | Injektionsvorrichtung mit Klauensicherung |
| EP1923085A1 (en) * | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
| CA2676810C (en) | 2007-02-05 | 2016-06-21 | Novo Nordisk A/S | Injection button |
| ES2388766T3 (es) * | 2007-11-20 | 2012-10-18 | Mallinckrodt Llc | Inyector de potencia con determinación de caudal y pantalla numérica |
| WO2009092807A1 (en) | 2008-01-23 | 2009-07-30 | Novo Nordisk A/S | Device for injecting apportioned doses of liquid drug |
| US8647309B2 (en) | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
| GB2461086B (en) * | 2008-06-19 | 2012-12-05 | Cilag Gmbh Int | Injection device |
| CN102202710B (zh) * | 2008-09-18 | 2013-08-21 | 贝克顿·迪金森公司 | 具有可旋转主体部的医用注射器 |
| US9199040B2 (en) | 2009-06-01 | 2015-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
-
2015
- 2015-03-13 CA CA2941978A patent/CA2941978A1/en not_active Abandoned
- 2015-03-13 EA EA201691813A patent/EA031626B1/ru not_active IP Right Cessation
- 2015-03-13 US US15/128,103 patent/US10350361B2/en active Active
- 2015-03-13 CR CR20160498A patent/CR20160498A/es unknown
- 2015-03-13 KR KR1020167028772A patent/KR20160138461A/ko not_active Withdrawn
- 2015-03-13 MA MA39366A patent/MA39366A1/fr unknown
- 2015-03-13 PE PE2016001696A patent/PE20170014A1/es not_active Application Discontinuation
- 2015-03-13 CN CN201580015846.5A patent/CN106132460B/zh not_active Expired - Fee Related
- 2015-03-13 JP JP2016557027A patent/JP6619355B2/ja not_active Expired - Fee Related
- 2015-03-13 AU AU2015237887A patent/AU2015237887B2/en not_active Ceased
- 2015-03-13 MX MX2016012392A patent/MX378982B/es unknown
- 2015-03-13 SG SG11201607861YA patent/SG11201607861YA/en unknown
- 2015-03-13 AP AP2016009513A patent/AP2016009513A0/en unknown
- 2015-03-13 WO PCT/IB2015/051843 patent/WO2015145294A1/en not_active Ceased
- 2015-03-13 EP EP15717057.2A patent/EP3122402B1/en active Active
- 2015-03-13 BR BR112016021889-2A patent/BR112016021889B1/pt active IP Right Grant
-
2016
- 2016-09-05 PH PH12016501743A patent/PH12016501743A1/en unknown
- 2016-09-06 ZA ZA2016/06181A patent/ZA201606181B/en unknown
- 2016-09-21 IL IL247956A patent/IL247956A0/en unknown
- 2016-09-22 CL CL2016002390A patent/CL2016002390A1/es unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1681070A1 (en) * | 2005-01-18 | 2006-07-19 | Wockhardt Americas Inc. | Pen shaped medication injection devices |
| CH703993A2 (de) * | 2012-02-09 | 2012-03-15 | Tecpharma Licensing Ag | Injektionsgerät zur Verabreichung oder Förderung von fluidem Produkt. |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015237887B2 (en) | 2018-10-04 |
| JP2017512539A (ja) | 2017-05-25 |
| CN106132460A (zh) | 2016-11-16 |
| BR112016021889A2 (cg-RX-API-DMAC7.html) | 2017-08-15 |
| MA39366A1 (fr) | 2017-03-31 |
| JP6619355B2 (ja) | 2019-12-11 |
| PH12016501743A1 (en) | 2016-11-07 |
| EP3122402B1 (en) | 2019-08-07 |
| KR20160138461A (ko) | 2016-12-05 |
| MX2016012392A (es) | 2016-11-30 |
| CN106132460B (zh) | 2019-10-29 |
| SG11201607861YA (en) | 2016-10-28 |
| EA201691813A1 (ru) | 2017-03-31 |
| CL2016002390A1 (es) | 2016-12-30 |
| EP3122402A1 (en) | 2017-02-01 |
| AU2015237887A1 (en) | 2016-09-22 |
| MX378982B (es) | 2025-03-11 |
| WO2015145294A1 (en) | 2015-10-01 |
| CR20160498A (es) | 2017-05-02 |
| AP2016009513A0 (en) | 2016-10-31 |
| ZA201606181B (en) | 2017-11-29 |
| IL247956A0 (en) | 2016-11-30 |
| US20180169345A1 (en) | 2018-06-21 |
| US10350361B2 (en) | 2019-07-16 |
| BR112016021889B1 (pt) | 2023-03-21 |
| CA2941978A1 (en) | 2015-10-01 |
| PE20170014A1 (es) | 2017-03-29 |
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