EA018994B1 - Производные бициклического амида для усиления глутаматергических синаптических ответов - Google Patents
Производные бициклического амида для усиления глутаматергических синаптических ответов Download PDFInfo
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- EA018994B1 EA018994B1 EA201101162A EA201101162A EA018994B1 EA 018994 B1 EA018994 B1 EA 018994B1 EA 201101162 A EA201101162 A EA 201101162A EA 201101162 A EA201101162 A EA 201101162A EA 018994 B1 EA018994 B1 EA 018994B1
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Classifications
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- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20664209P | 2009-02-02 | 2009-02-02 | |
| PCT/US2010/000255 WO2010087981A2 (en) | 2009-02-02 | 2010-01-29 | Bicyclic amide derivatives for enhancing glutamatergic synaptic responses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201101162A1 EA201101162A1 (ru) | 2012-01-30 |
| EA018994B1 true EA018994B1 (ru) | 2013-12-30 |
Family
ID=42396261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201101162A EA018994B1 (ru) | 2009-02-02 | 2010-01-29 | Производные бициклического амида для усиления глутаматергических синаптических ответов |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP2391621A4 (OSRAM) |
| JP (1) | JP2012516845A (OSRAM) |
| KR (1) | KR20110115139A (OSRAM) |
| CN (1) | CN102369201A (OSRAM) |
| AU (1) | AU2010208646A1 (OSRAM) |
| BR (1) | BRPI1005316A2 (OSRAM) |
| CA (1) | CA2751285A1 (OSRAM) |
| EA (1) | EA018994B1 (OSRAM) |
| IL (1) | IL214392A0 (OSRAM) |
| MX (1) | MX2011008060A (OSRAM) |
| SG (1) | SG173168A1 (OSRAM) |
| WO (2) | WO2010087981A2 (OSRAM) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998035950A1 (en) * | 1997-02-13 | 1998-08-20 | Cortex Pharmaceuticals, Inc. | Benzofurazan compounds which enhance ampa receptor activity |
| WO1999021422A1 (en) * | 1997-10-27 | 1999-05-06 | Cortex Pharmaceuticals, Inc. | Treatment of schizophrenia with ampakines and neuroleptics |
| WO2008143963A1 (en) * | 2007-05-17 | 2008-11-27 | Cortex Pharmaceuticals, Inc. | Di-substituted amides for enhancing glutamatergic synaptic responses |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT651746E (pt) * | 1992-07-24 | 2002-09-30 | Univ California | Drogas que intensificam as respostas sinapticas mediadas por receptores de ampa |
| US20020099050A1 (en) * | 1993-07-23 | 2002-07-25 | Lynch Gary S. | Drugs that enhance synaptic responses mediated by AMPA receptors |
| AU2008287445A1 (en) * | 2007-08-10 | 2009-02-19 | Cortex Pharmaceuticals, Inc. | Bicyclic amides for enhancing glutamatergic synaptic responses |
-
2010
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- 2010-01-29 SG SG2011054376A patent/SG173168A1/en unknown
- 2010-01-29 EA EA201101162A patent/EA018994B1/ru not_active IP Right Cessation
- 2010-01-29 BR BRPI1005316A patent/BRPI1005316A2/pt not_active IP Right Cessation
- 2010-01-29 WO PCT/US2010/000255 patent/WO2010087981A2/en not_active Ceased
- 2010-01-29 EP EP10736150A patent/EP2391621A4/en not_active Withdrawn
- 2010-01-29 MX MX2011008060A patent/MX2011008060A/es active IP Right Grant
- 2010-01-29 KR KR1020117019461A patent/KR20110115139A/ko not_active Withdrawn
- 2010-01-29 CA CA2751285A patent/CA2751285A1/en not_active Abandoned
- 2010-01-29 WO PCT/US2010/000254 patent/WO2010087980A2/en not_active Ceased
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- 2010-01-29 JP JP2011547981A patent/JP2012516845A/ja active Pending
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2011
- 2011-08-01 IL IL214392A patent/IL214392A0/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998035950A1 (en) * | 1997-02-13 | 1998-08-20 | Cortex Pharmaceuticals, Inc. | Benzofurazan compounds which enhance ampa receptor activity |
| WO1999021422A1 (en) * | 1997-10-27 | 1999-05-06 | Cortex Pharmaceuticals, Inc. | Treatment of schizophrenia with ampakines and neuroleptics |
| WO2008143963A1 (en) * | 2007-05-17 | 2008-11-27 | Cortex Pharmaceuticals, Inc. | Di-substituted amides for enhancing glutamatergic synaptic responses |
Also Published As
| Publication number | Publication date |
|---|---|
| SG173168A1 (en) | 2011-08-29 |
| MX2011008060A (es) | 2011-09-09 |
| WO2010087980A3 (en) | 2011-02-24 |
| EP2391621A2 (en) | 2011-12-07 |
| EA201101162A1 (ru) | 2012-01-30 |
| WO2010087981A3 (en) | 2011-03-24 |
| WO2010087981A2 (en) | 2010-08-05 |
| CA2751285A1 (en) | 2010-08-05 |
| CN102369201A (zh) | 2012-03-07 |
| AU2010208646A1 (en) | 2011-09-01 |
| KR20110115139A (ko) | 2011-10-20 |
| BRPI1005316A2 (pt) | 2019-09-24 |
| IL214392A0 (en) | 2011-09-27 |
| WO2010087980A2 (en) | 2010-08-05 |
| EP2391621A4 (en) | 2012-07-25 |
| JP2012516845A (ja) | 2012-07-26 |
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