EA010906B1 - Макролиды, обладающие противовоспалительной активностью - Google Patents

Макролиды, обладающие противовоспалительной активностью Download PDF

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Publication number
EA010906B1
EA010906B1 EA200601368A EA200601368A EA010906B1 EA 010906 B1 EA010906 B1 EA 010906B1 EA 200601368 A EA200601368 A EA 200601368A EA 200601368 A EA200601368 A EA 200601368A EA 010906 B1 EA010906 B1 EA 010906B1
Authority
EA
Eurasian Patent Office
Prior art keywords
group
alkyl group
hydrogen atom
alkyl
phenyl
Prior art date
Application number
EA200601368A
Other languages
English (en)
Russian (ru)
Other versions
EA200601368A1 (ru
Inventor
Андреа Мереу
Мауро Наполетано
Фернандо Орнаги
Ерманно Моригги
Франко Пеллачини
Original Assignee
Дзамбон Гроуп С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзамбон Гроуп С.П.А. filed Critical Дзамбон Гроуп С.П.А.
Publication of EA200601368A1 publication Critical patent/EA200601368A1/ru
Publication of EA010906B1 publication Critical patent/EA010906B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EA200601368A 2004-01-29 2005-01-25 Макролиды, обладающие противовоспалительной активностью EA010906B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000124A ITMI20040124A1 (it) 2004-01-29 2004-01-29 Macrolidi ad attivita' antiinfiammatoria
PCT/EP2005/050312 WO2005075494A1 (en) 2004-01-29 2005-01-25 Macrolides with antiinflammatory activity

Publications (2)

Publication Number Publication Date
EA200601368A1 EA200601368A1 (ru) 2007-02-27
EA010906B1 true EA010906B1 (ru) 2008-12-30

Family

ID=34835570

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601368A EA010906B1 (ru) 2004-01-29 2005-01-25 Макролиды, обладающие противовоспалительной активностью

Country Status (10)

Country Link
US (1) US7507721B2 (enExample)
EP (1) EP1713818A1 (enExample)
JP (1) JP4709774B2 (enExample)
CN (1) CN1956993B (enExample)
AU (1) AU2005210032B9 (enExample)
CA (1) CA2554070C (enExample)
EA (1) EA010906B1 (enExample)
IL (1) IL176846A (enExample)
IT (1) ITMI20040124A1 (enExample)
WO (1) WO2005075494A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
WO2007129646A1 (ja) 2006-05-01 2007-11-15 Taisho Pharmaceutical Co., Ltd. マクロライド誘導体
ES2391653T3 (es) * 2006-12-12 2012-11-28 Zambon S.P.A. Compuestos macrólidos dotados de actividad antiinflamatoria
EP4118091B1 (en) 2020-03-12 2025-06-18 Zoetis Services LLC Immunomodulating urea azalides
CA3231535A1 (en) * 2021-09-07 2023-03-16 Zoetis Services Llc Immunomodulating azalides
CN121038797A (zh) * 2023-03-22 2025-11-28 艾比恩多制药有限责任公司 用于治疗嗜酸性粒细胞相关疾病的阿奇霉素衍生物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
WO2000042055A2 (en) * 1999-01-15 2000-07-20 Zambon Group S.P.A. Macrolides with anti-inflammatory activity
WO2004013153A2 (en) * 2002-08-01 2004-02-12 Zambon Group S.P.A. Macrolide compounds endowed with antiinflammatory activity

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
WO2000042055A2 (en) * 1999-01-15 2000-07-20 Zambon Group S.P.A. Macrolides with anti-inflammatory activity
WO2004013153A2 (en) * 2002-08-01 2004-02-12 Zambon Group S.P.A. Macrolide compounds endowed with antiinflammatory activity

Also Published As

Publication number Publication date
JP4709774B2 (ja) 2011-06-22
US7507721B2 (en) 2009-03-24
AU2005210032A1 (en) 2005-08-18
WO2005075494A1 (en) 2005-08-18
EA200601368A1 (ru) 2007-02-27
CN1956993B (zh) 2012-10-31
AU2005210032B2 (en) 2011-01-20
IL176846A0 (en) 2006-10-31
US20070167381A1 (en) 2007-07-19
CA2554070C (en) 2011-10-11
CA2554070A1 (en) 2005-08-18
EP1713818A1 (en) 2006-10-25
AU2005210032B9 (en) 2011-06-09
CN1956993A (zh) 2007-05-02
JP2007519685A (ja) 2007-07-19
ITMI20040124A1 (it) 2004-04-29
IL176846A (en) 2011-01-31

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU