EA006368B1 - Химически модифицированные конъюгаты прогенипоэтина - Google Patents
Химически модифицированные конъюгаты прогенипоэтина Download PDFInfo
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- EA006368B1 EA006368B1 EA200400070A EA200400070A EA006368B1 EA 006368 B1 EA006368 B1 EA 006368B1 EA 200400070 A EA200400070 A EA 200400070A EA 200400070 A EA200400070 A EA 200400070A EA 006368 B1 EA006368 B1 EA 006368B1
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- peg
- progenipoietin
- ξεο
- modified
- polyethylene glycol
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- 230000026683 transduction Effects 0.000 description 1
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- 238000002054 transplantation Methods 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30036201P | 2001-06-22 | 2001-06-22 | |
| PCT/US2002/018810 WO2003000179A2 (en) | 2001-06-22 | 2002-06-14 | Chemically-modified progenipoietin conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200400070A1 EA200400070A1 (ru) | 2004-06-24 |
| EA006368B1 true EA006368B1 (ru) | 2005-12-29 |
Family
ID=23158770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200400070A EA006368B1 (ru) | 2001-06-22 | 2002-06-14 | Химически модифицированные конъюгаты прогенипоэтина |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060052291A1 (https=) |
| EP (1) | EP1404354A4 (https=) |
| JP (1) | JP2005512951A (https=) |
| KR (1) | KR20040069980A (https=) |
| CN (1) | CN101426511A (https=) |
| BR (1) | BR0211192A (https=) |
| CA (1) | CA2450950A1 (https=) |
| CZ (1) | CZ20033537A3 (https=) |
| EA (1) | EA006368B1 (https=) |
| IL (1) | IL159496A0 (https=) |
| MX (1) | MXPA04000068A (https=) |
| NO (1) | NO20035742L (https=) |
| PL (1) | PL367410A1 (https=) |
| WO (1) | WO2003000179A2 (https=) |
| ZA (1) | ZA200309863B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12398176B2 (en) | 2018-08-27 | 2025-08-26 | Regeneron Pharmaceuticals, Inc. | Use of Raman spectroscopy in downstream purification |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006215823A1 (en) * | 2005-02-16 | 2006-08-24 | Micromet Ag | Use of activated polymers for separation of protein and polypeptide multimers |
| WO2006102659A2 (en) * | 2005-03-23 | 2006-09-28 | Nektar Therapeutics Al, Corporation | CONJUGATES OF AN hGH MOIETY AND A POLYMER |
| US8951769B2 (en) | 2009-04-20 | 2015-02-10 | The Regents Of The University Of California | Engineered demeter 5-methylcytosine DNA glyosylase with improved yield, stability and solubility |
| KR200483859Y1 (ko) | 2015-10-28 | 2017-07-04 | 주식회사 키유틸리티 | 충전장치 수납 및 휴대용 기기 거치용 장치 |
| WO2019075053A1 (en) * | 2017-10-11 | 2019-04-18 | Elanco Us Inc. | PORCINE G-CSF VARIANTS AND USES THEREOF |
| CN111741770A (zh) * | 2017-12-29 | 2020-10-02 | 豪夫迈·罗氏有限公司 | 用于提供聚乙二醇化蛋白质组合物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69431295T2 (de) * | 1993-04-21 | 2003-05-15 | Institut Pasteur, Paris | Biokompatibles implantat zur in vivo expression und sekretion von therapeutischer verbindung |
| US5730990A (en) * | 1994-06-24 | 1998-03-24 | Enzon, Inc. | Non-antigenic amine derived polymers and polymer conjugates |
| GB2294047A (en) * | 1994-10-14 | 1996-04-17 | Merck & Co Inc | Synthetic peptides for use as epitopes specific for HIV |
| SE507527C2 (sv) * | 1996-10-11 | 1998-06-15 | Ericsson Telefon Ab L M | Flerbandsmottagare som genererar en mellanfrekvens som är gemensam för de olika frekvensbanden, och förfarande för densamma |
| US6251665B1 (en) * | 1997-02-07 | 2001-06-26 | Cem Cezayirli | Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom |
-
2002
- 2002-06-14 IL IL15949602A patent/IL159496A0/xx unknown
- 2002-06-14 MX MXPA04000068A patent/MXPA04000068A/es unknown
- 2002-06-14 PL PL02367410A patent/PL367410A1/xx unknown
- 2002-06-14 BR BR0211192-6A patent/BR0211192A/pt not_active IP Right Cessation
- 2002-06-14 KR KR10-2003-7016759A patent/KR20040069980A/ko not_active Withdrawn
- 2002-06-14 EA EA200400070A patent/EA006368B1/ru not_active IP Right Cessation
- 2002-06-14 JP JP2003506625A patent/JP2005512951A/ja not_active Abandoned
- 2002-06-14 US US10/481,935 patent/US20060052291A1/en not_active Abandoned
- 2002-06-14 WO PCT/US2002/018810 patent/WO2003000179A2/en not_active Ceased
- 2002-06-14 CZ CZ20033537A patent/CZ20033537A3/cs unknown
- 2002-06-14 CN CNA028165179A patent/CN101426511A/zh active Pending
- 2002-06-14 EP EP02742060A patent/EP1404354A4/en not_active Withdrawn
- 2002-06-14 CA CA002450950A patent/CA2450950A1/en not_active Abandoned
-
2003
- 2003-12-19 NO NO20035742A patent/NO20035742L/no not_active Application Discontinuation
- 2003-12-19 ZA ZA200309863A patent/ZA200309863B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12398176B2 (en) | 2018-08-27 | 2025-08-26 | Regeneron Pharmaceuticals, Inc. | Use of Raman spectroscopy in downstream purification |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040069980A (ko) | 2004-08-06 |
| WO2003000179A2 (en) | 2003-01-03 |
| BR0211192A (pt) | 2004-10-26 |
| CZ20033537A3 (cs) | 2004-08-18 |
| NO20035742D0 (no) | 2003-12-19 |
| WO2003000179A3 (en) | 2003-12-11 |
| PL367410A1 (en) | 2005-02-21 |
| NO20035742L (no) | 2004-02-23 |
| ZA200309863B (https=) | 2006-06-28 |
| CN101426511A (zh) | 2009-05-06 |
| US20060052291A1 (en) | 2006-03-09 |
| JP2005512951A (ja) | 2005-05-12 |
| EP1404354A2 (en) | 2004-04-07 |
| IL159496A0 (en) | 2004-06-01 |
| EA200400070A1 (ru) | 2004-06-24 |
| CA2450950A1 (en) | 2003-01-03 |
| MXPA04000068A (es) | 2005-06-06 |
| EP1404354A4 (en) | 2005-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |