DOP2004000986A - BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY - Google Patents

BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY

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Publication number
DOP2004000986A
DOP2004000986A DO2004000986A DO2004000986A DOP2004000986A DO P2004000986 A DOP2004000986 A DO P2004000986A DO 2004000986 A DO2004000986 A DO 2004000986A DO 2004000986 A DO2004000986 A DO 2004000986A DO P2004000986 A DOP2004000986 A DO P2004000986A
Authority
DO
Dominican Republic
Prior art keywords
disease
compounds
dyspepsia
irritable bowel
gastroesophageal reflux
Prior art date
Application number
DO2004000986A
Other languages
Spanish (es)
Inventor
Hiroki Sone
Chikara Uchida
Yasuhiro Katsu
Takashi Kojima
Satoru Iguchi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to DO2004000986A priority Critical patent/DOP2004000986A/en
Publication of DOP2004000986A publication Critical patent/DOP2004000986A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invencion proporciona un compuesto de formula (I): o una sal farmaceuticamente aceptable del mismo, y composiciones que contienen dichos compuestos y el use de dichos compuestos para la preparacion de un medicamento para enfermedad por reflujo gastroesofagico, enfermedad gastrointestinal, trastorno de motilidad gastrica, dispepsia noulcerosa, dispepsia funcional, sindrome de intestino irritable (IBS), estrenimiento, dispepsia, esofagitis, enfermedad gastresofagica, nauseas, enfermedad del sistema nervioso central, enfermedad de Alzheimer, trastomo cognitivo, emesis, migranas, enfermedad neurologica, dolor, trastomos cardiovasculares, insuficiencia cardiaca, arritmia cardiaca, diabetes y sindrome de apnea. Estos compuestos tienen actividad agonista del receptor 5-HT4, y por lo tanto son utiles para el tratamiento de enfermedad por reflujo gastroesofagico, dispepsia no ulcerosa, dispepsia funcional, sindrome de intestino irritable o similares en mamiferos, especialmente en seres humanos.This invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and compositions containing said compounds and the use of said compounds for the preparation of a medicament for gastroesophageal reflux disease, gastrointestinal disease, gastric motility disorder , noulcerous dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastresophageal disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraines, neurological disease, pain, cardiovascular disorders , heart failure, cardiac arrhythmia, diabetes and apnea syndrome. These compounds have 5-HT4 receptor agonist activity, and are therefore useful for the treatment of gastroesophageal reflux disease, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome or the like in mammals, especially in humans.

DO2004000986A 2004-08-31 2004-08-31 BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY DOP2004000986A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DO2004000986A DOP2004000986A (en) 2004-08-31 2004-08-31 BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DO2004000986A DOP2004000986A (en) 2004-08-31 2004-08-31 BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY

Publications (1)

Publication Number Publication Date
DOP2004000986A true DOP2004000986A (en) 2005-03-15

Family

ID=44261402

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2004000986A DOP2004000986A (en) 2004-08-31 2004-08-31 BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY

Country Status (1)

Country Link
DO (1) DOP2004000986A (en)

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