CU20070183A7 - OXINDOL DERIVATIVES - Google Patents

OXINDOL DERIVATIVES

Info

Publication number
CU20070183A7
CU20070183A7 CU20070183A CU20070183A CU20070183A7 CU 20070183 A7 CU20070183 A7 CU 20070183A7 CU 20070183 A CU20070183 A CU 20070183A CU 20070183 A CU20070183 A CU 20070183A CU 20070183 A7 CU20070183 A7 CU 20070183A7
Authority
CU
Cuba
Prior art keywords
disease
compounds
dyspepsia
disorder
pharmaceutically acceptable
Prior art date
Application number
CU20070183A
Other languages
Spanish (es)
Inventor
Kiyoshi Kawamura
Chikara Uchida
Hiroki Sone
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CU20070183A priority Critical patent/CU20070183A7/en
Publication of CU20070183A7 publication Critical patent/CU20070183A7/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere a compuestos de la fórmula (I) ESPACIO PARA FÓRMULA (I) o una sal farmacéuticamente aceptable del mismo, en la que: cada uno de A, R1, R2, R3, R4 y R5 es como se describe en este documento o una sal farmacéuticvamente aceptable, y composiciones que contienen dichos compuestos y el uso de dichos compuestos en el tratamiento de una afección mediada por la actividad agonista de 5-HT4 tales como, aunque sin limitación, enfermedad de reflujo gastroesofágeo, enfermedad gastrointestinal, trastorno de motilidad gástrica, dispepsia no ulcerosa, dispepsia funcional, síndrome del intestino irritable (IBS), estrenimiento, dispepsia, esofagitis, enfermedad gasatroesofágea, náuseas, enfermedad del sistema nervioso central, enfermedad de Alzheimer, trastorno cognitivo, emesis, migrana, enfermedad neurológica, dolor, trastorno cardiovasculares, insufiencia cardiaca, arritmia cardiaca, diabetes o síndrome de apnea.This invention relates to compounds of the formula (I) FORMULA SPACE (I) or a pharmaceutically acceptable salt thereof, in which: each of A, R1, R2, R3, R4 and R5 is as described herein. document or a pharmaceutically acceptable salt, and compositions containing said compounds and the use of said compounds in the treatment of a condition mediated by the agonist activity of 5-HT4 such as, but not limited to, gastroesophageal reflux disease, gastrointestinal disease, disorder of gastric motility, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageal disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorder, heart failure, cardiac arrhythmia, diabetes or apnea syndrome.

CU20070183A 2007-08-06 2007-08-06 OXINDOL DERIVATIVES CU20070183A7 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CU20070183A CU20070183A7 (en) 2007-08-06 2007-08-06 OXINDOL DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20070183A CU20070183A7 (en) 2007-08-06 2007-08-06 OXINDOL DERIVATIVES

Publications (1)

Publication Number Publication Date
CU20070183A7 true CU20070183A7 (en) 2009-03-16

Family

ID=44280833

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20070183A CU20070183A7 (en) 2007-08-06 2007-08-06 OXINDOL DERIVATIVES

Country Status (1)

Country Link
CU (1) CU20070183A7 (en)

Similar Documents

Publication Publication Date Title
DOP2006000046A (en) OXINDOL DERIVATIVES
UY29421A1 (en) NEW COMPOUNDS OF N- (N-SULFONYLAMINOARILMETIL) CYCLOPROPANOCARBOXANIDA SUBSTITUTED, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TO APPLICATIONS.
ECSP067079A (en) BENCIMIDAZOLONA CARBOXYL ACID DERIVATIVES
DE602006010563D1 (en) INDAZOLCARBOXYL ACID AMID DERIVATIVES AS AGONISTS OF THE 5HT4 RECEPTOR
UY28496A1 (en) BENCIMIDAZOLONE COMPOUNDS THAT HAVE AGENIST ACTIVITY OF THE RECEIVER 5-HT4
PE20080361A1 (en) PURINE-DERIVED COMPOUNDS AS ADENOSINE A2A RECEPTOR ACTIVATORS
NO20090739L (en) Chemical connections
PE20090183A1 (en) DERIVATIVES OF 1-OXA-3,9-DIAZA-ESPIRO- [5.5] UNDECAN-2-ONA AS CCR5 MODULATORS
TW200621245A (en) Thienopyridinone compounds and methods of treatment
AR061656A1 (en) BENCILPIPERAZINE COMPOSITE, ITS USE TO PREPARE A MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND PROCESSES FOR THE PREPARATION OF COMPOSITION AND COMPOSITION
EA200870591A1 (en) 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR APPLICATION AS THE NICOTINE RECEPTOR OF ACETYLCHOLINE AS LIGANDS
EA201070916A1 (en) DOUBLE PHARMACOFOR - PDE4-MUSCARINE ANTAGONISTS
NZ602612A (en) Novel benzamide derivatives
PE20090115A1 (en) INDOL-2-IL-PIPERAZIN-1-IL-METHANONE DERIVATIVES
EA201001645A1 (en) HINUCLIDINE DERIVATIVES AS ANTAGONISTS OF MUSCARINE M3 RECEPTOR
CU20070183A7 (en) OXINDOL DERIVATIVES
DOP2005000113A (en) BENCIMIDAZOLONA CARBOXILIC ACID DRIVATES
DOP2004000986A (en) BENCIMIDAZOLONE COMPOUNDS THAT HAVE 5HT-4 RECEIVER ACTIVITY
TH81015B (en) Oxiindole derivatives
TH108044B (en) Aminotetrahydropyran as an inhibitor of dipeptidyl peptidase-IV for therapeutic use Or prevention of diabetes
TH106943B (en) Benzimidazolone compounds with anti-active 5-HT4 receptor
TH106943A (en) Benzimidazolone compounds with anti-active 5-HT4 receptor
TH107697A (en) Pirolopiridine and its use as a BACE inhibitor.
TH81015A (en) Oxidole derivatives
UY27504A1 (en) IMIDAZOPIRIDIN COMPOUNDS AS 5-HT4 RECEIVER MODULATORS