CU20070183A7 - OXINDOL DERIVATIVES - Google Patents
OXINDOL DERIVATIVESInfo
- Publication number
- CU20070183A7 CU20070183A7 CU20070183A CU20070183A CU20070183A7 CU 20070183 A7 CU20070183 A7 CU 20070183A7 CU 20070183 A CU20070183 A CU 20070183A CU 20070183 A CU20070183 A CU 20070183A CU 20070183 A7 CU20070183 A7 CU 20070183A7
- Authority
- CU
- Cuba
- Prior art keywords
- disease
- compounds
- dyspepsia
- disorder
- pharmaceutically acceptable
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invención se refiere a compuestos de la fórmula (I) ESPACIO PARA FÓRMULA (I) o una sal farmacéuticamente aceptable del mismo, en la que: cada uno de A, R1, R2, R3, R4 y R5 es como se describe en este documento o una sal farmacéuticvamente aceptable, y composiciones que contienen dichos compuestos y el uso de dichos compuestos en el tratamiento de una afección mediada por la actividad agonista de 5-HT4 tales como, aunque sin limitación, enfermedad de reflujo gastroesofágeo, enfermedad gastrointestinal, trastorno de motilidad gástrica, dispepsia no ulcerosa, dispepsia funcional, síndrome del intestino irritable (IBS), estrenimiento, dispepsia, esofagitis, enfermedad gasatroesofágea, náuseas, enfermedad del sistema nervioso central, enfermedad de Alzheimer, trastorno cognitivo, emesis, migrana, enfermedad neurológica, dolor, trastorno cardiovasculares, insufiencia cardiaca, arritmia cardiaca, diabetes o síndrome de apnea.This invention relates to compounds of the formula (I) FORMULA SPACE (I) or a pharmaceutically acceptable salt thereof, in which: each of A, R1, R2, R3, R4 and R5 is as described herein. document or a pharmaceutically acceptable salt, and compositions containing said compounds and the use of said compounds in the treatment of a condition mediated by the agonist activity of 5-HT4 such as, but not limited to, gastroesophageal reflux disease, gastrointestinal disease, disorder of gastric motility, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome (IBS), constipation, dyspepsia, esophagitis, gastroesophageal disease, nausea, central nervous system disease, Alzheimer's disease, cognitive disorder, emesis, migraine, neurological disease, pain, cardiovascular disorder, heart failure, cardiac arrhythmia, diabetes or apnea syndrome.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20070183A CU20070183A7 (en) | 2007-08-06 | 2007-08-06 | OXINDOL DERIVATIVES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20070183A CU20070183A7 (en) | 2007-08-06 | 2007-08-06 | OXINDOL DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
CU20070183A7 true CU20070183A7 (en) | 2009-03-16 |
Family
ID=44280833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU20070183A CU20070183A7 (en) | 2007-08-06 | 2007-08-06 | OXINDOL DERIVATIVES |
Country Status (1)
Country | Link |
---|---|
CU (1) | CU20070183A7 (en) |
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2007
- 2007-08-06 CU CU20070183A patent/CU20070183A7/en unknown
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