DOP2003000788A - INDAZOL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS TO INHIBIT PROTEINKINES, AND PROCEDURES FOR USE - Google Patents
INDAZOL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS TO INHIBIT PROTEINKINES, AND PROCEDURES FOR USEInfo
- Publication number
- DOP2003000788A DOP2003000788A DO2003000788A DO2003000788A DOP2003000788A DO P2003000788 A DOP2003000788 A DO P2003000788A DO 2003000788 A DO2003000788 A DO 2003000788A DO 2003000788 A DO2003000788 A DO 2003000788A DO P2003000788 A DOP2003000788 A DO P2003000788A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- compounds
- pharmaceutical compositions
- inhibit
- proteinkines
- procedures
- Prior art date
Links
Abstract
Se describen compuestos de indazol que modulan y/o inhiben las enfermedades oftalmicas y la actividad de ciertas proteinquinasas. Estos compuestos y composiciones farmaceuticas que los contienen son capaces de mediar la transducción de la sepal de tirosina quinasa y por lo tanto modular y/o inhibir la proliferacion celular no deseada. La invención tambien se refiere al use terapeutico o profilactico de las composiciones farmaceuticas que contienen dichos compuestos, y a procedimientos de tratamiento de enfermedades oftalmicas y cancer y otros estados de enfermedad asociados con angiogenesis y/o proliferacion celular no deseadas, tales como retinopatia diabetica, glaucoma neovascular, artritis reumatoide y psoriasis, mediante la administracion de cantidades eficaces de dichos compuestos.Indazole compounds that modulate and / or inhibit ophthalmic diseases and the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating the transduction of the tyrosine kinase sepal and therefore modulating and / or inhibiting unwanted cell proliferation. The invention also relates to the therapeutic or prophylactic use of pharmaceutical compositions containing said compounds, and to methods of treatment of ophthalmic diseases and cancer and other disease states associated with unwanted angiogenesis and / or cell proliferation, such as diabetic retinopathy, glaucoma. neovascular, rheumatoid arthritis and psoriasis, by administering effective amounts of said compounds.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2003000788A DOP2003000788A (en) | 2003-12-10 | 2003-12-10 | INDAZOL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS TO INHIBIT PROTEINKINES, AND PROCEDURES FOR USE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2003000788A DOP2003000788A (en) | 2003-12-10 | 2003-12-10 | INDAZOL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS TO INHIBIT PROTEINKINES, AND PROCEDURES FOR USE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2003000788A true DOP2003000788A (en) | 2004-06-30 |
Family
ID=44261273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2003000788A DOP2003000788A (en) | 2003-12-10 | 2003-12-10 | INDAZOL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS TO INHIBIT PROTEINKINES, AND PROCEDURES FOR USE |
Country Status (1)
| Country | Link |
|---|---|
| DO (1) | DOP2003000788A (en) |
-
2003
- 2003-12-10 DO DO2003000788A patent/DOP2003000788A/en unknown
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