DK95284A - Krystalliseret kulhydratmatrix for biologisk aktive stoffer, fremgangsmaade til fremstilling deraf samt dens anvendelse - Google Patents

Krystalliseret kulhydratmatrix for biologisk aktive stoffer, fremgangsmaade til fremstilling deraf samt dens anvendelse Download PDF

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Publication number
DK95284A
DK95284A DK95284A DK95284A DK95284A DK 95284 A DK95284 A DK 95284A DK 95284 A DK95284 A DK 95284A DK 95284 A DK95284 A DK 95284A DK 95284 A DK95284 A DK 95284A
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Prior art keywords
procedures
production
application
biologically active
active substances
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Application number
DK95284A
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Danish (da)
English (en)
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DK95284D0 (da
Inventor
Ulf Schroeder
Original Assignee
Ulf Schroeder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ulf Schroeder filed Critical Ulf Schroeder
Publication of DK95284D0 publication Critical patent/DK95284D0/da
Publication of DK95284A publication Critical patent/DK95284A/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK95284A 1982-07-09 1984-02-23 Krystalliseret kulhydratmatrix for biologisk aktive stoffer, fremgangsmaade til fremstilling deraf samt dens anvendelse DK95284A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8204244A SE8204244L (sv) 1982-07-09 1982-07-09 Kristalliserad kolhydratsmatris for biologiskt aktiva substanser
PCT/SE1983/000268 WO1984000294A1 (en) 1982-07-09 1983-07-04 A crystallised carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof

Publications (2)

Publication Number Publication Date
DK95284D0 DK95284D0 (da) 1984-02-23
DK95284A true DK95284A (da) 1984-02-23

Family

ID=20347337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95284A DK95284A (da) 1982-07-09 1984-02-23 Krystalliseret kulhydratmatrix for biologisk aktive stoffer, fremgangsmaade til fremstilling deraf samt dens anvendelse

Country Status (9)

Country Link
EP (1) EP0113749B1 (de)
JP (1) JPS59501213A (de)
AU (1) AU567434B2 (de)
DE (1) DE3376797D1 (de)
DK (1) DK95284A (de)
FI (1) FI840923A0 (de)
NO (1) NO840676L (de)
SE (1) SE8204244L (de)
WO (1) WO1984000294A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5720939A (en) * 1985-08-15 1998-02-24 Nycomed Imaging As Method of contrast enhanced magnetic resonance imaging using magnetically responsive-particles
US5618514A (en) * 1983-12-21 1997-04-08 Nycomed Imaging As Diagnostic and contrast agent
JPS60175539A (ja) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd カプセル体およびその製造法
US5266333A (en) * 1985-03-06 1993-11-30 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration of growth hormone
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US4925678A (en) * 1987-04-01 1990-05-15 Ranney David F Endothelial envelopment drug carriers
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
US5108759A (en) * 1987-04-01 1992-04-28 Ranney David F Endothelial envelopment drug carriers
SE8701479L (sv) * 1987-04-09 1988-10-10 Carbomatrix Ab Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
EP0586524B2 (de) * 1991-06-03 2000-11-02 Nycomed Imaging As Verbesserungen im bezug auf kontrastmittel
GB9116610D0 (en) * 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
FR2692168B1 (fr) * 1992-06-16 1995-03-24 Centre Nat Rech Scient Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères.
DK0748213T3 (da) * 1994-03-07 2004-08-02 Nektar Therapeutics Fremgangsmåder og sammensætninger til pulmonal indgivelse af insulin
ATE223235T1 (de) * 1994-09-23 2002-09-15 Zonagen Inc Chitosan induzierte verstärkung
US5912000A (en) * 1994-09-23 1999-06-15 Zonagen, Inc. Chitosan induced immunopotentiation
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
IT1297461B1 (it) * 1997-10-29 1999-12-17 Ciocca Maurizio Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili
EP1184032A1 (de) * 2000-08-31 2002-03-06 OctoPlus B.V. Dextranhydrogele
EP1356826A1 (de) 2002-04-22 2003-10-29 BIOMAY Produktions- und Handels- Aktiengesellschaft Mikropartikel die Kohlenhydratkugeln enthalten an welche ein Allergen kovalent gebunden sind
DE602004029630D1 (de) * 2003-03-04 2010-12-02 Technology Dev Co Ltd Injizierbare Insulinzubereitung mit Langzeitwirkung und Verfahren zur dessen Herstellung und Verwendung
EP1576952A1 (de) * 2004-03-18 2005-09-21 OctoPlus Technologies B.V. Hydrogel-Mikrosphären mit verbessertem Freisetzungsprofil
SE0600091L (sv) 2006-01-18 2007-04-17 Bows Pharmaceuticals Ag Förfarande för framställning av en dextranmatris för kontrollerad frisättning av insulin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52136911A (en) * 1976-05-06 1977-11-16 Eisai Co Ltd Solid ubidecarenone agent
JPS603998B2 (ja) * 1977-04-19 1985-01-31 凸版印刷株式会社 合成樹脂成形物への加熱転写法
JPS5547615A (en) * 1978-09-29 1980-04-04 Taiyo Yakuhin Kogyo Kk Stable solid drug of nifedipine
SE445013B (sv) * 1979-06-21 1986-05-26 Landstingens Inkopscentral Medel for att forebygga eller behandla infektioner hos menniskor och djur
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
DE3147714A1 (de) * 1981-11-27 1983-06-01 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacycline und verfahren zu ihrer herstellung
US5855764A (en) * 1997-07-15 1999-01-05 Exxon Research And Engineering Company Method for demetallating petroleum streams

Also Published As

Publication number Publication date
AU1776083A (en) 1984-02-08
DK95284D0 (da) 1984-02-23
SE8204244L (sv) 1984-01-10
SE8204244D0 (sv) 1982-07-09
EP0113749B1 (de) 1988-06-01
FI840923A (fi) 1984-03-07
NO840676L (no) 1984-02-22
WO1984000294A1 (en) 1984-02-02
FI840923A0 (fi) 1984-03-07
DE3376797D1 (en) 1988-07-07
EP0113749A1 (de) 1984-07-25
JPS59501213A (ja) 1984-07-12
AU567434B2 (en) 1987-11-19

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