DK69285A - Tetrahydroimidazolderivater - Google Patents

Tetrahydroimidazolderivater Download PDF

Info

Publication number
DK69285A
DK69285A DK69285A DK69285A DK69285A DK 69285 A DK69285 A DK 69285A DK 69285 A DK69285 A DK 69285A DK 69285 A DK69285 A DK 69285A DK 69285 A DK69285 A DK 69285A
Authority
DK
Denmark
Prior art keywords
tetrahydroimidazole
derivatives
tetrahydroimidazole derivatives
Prior art date
Application number
DK69285A
Other languages
Danish (da)
English (en)
Other versions
DK69285D0 (da
Inventor
John H Fried
Michael C Venuti
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK69285D0 publication Critical patent/DK69285D0/da
Publication of DK69285A publication Critical patent/DK69285A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK69285A 1984-02-15 1985-02-14 Tetrahydroimidazolderivater DK69285A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58040984A 1984-02-15 1984-02-15

Publications (2)

Publication Number Publication Date
DK69285D0 DK69285D0 (da) 1985-02-14
DK69285A true DK69285A (da) 1985-08-16

Family

ID=24320992

Family Applications (1)

Application Number Title Priority Date Filing Date
DK69285A DK69285A (da) 1984-02-15 1985-02-14 Tetrahydroimidazolderivater

Country Status (13)

Country Link
US (1) US4690925A (de)
EP (1) EP0153152A3 (de)
JP (1) JPS60193991A (de)
AU (1) AU581205B2 (de)
CA (1) CA1254557A (de)
DK (1) DK69285A (de)
ES (2) ES8607299A1 (de)
FI (1) FI81578C (de)
HU (2) HU191316B (de)
IL (1) IL74349A (de)
NO (1) NO164654C (de)
NZ (1) NZ211117A (de)
ZA (1) ZA851131B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4490371A (en) * 1983-02-16 1984-12-25 Syntex (U.S.A.) Inc. N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
ES8607299A1 (es) * 1984-02-15 1986-06-01 Syntex Inc Procedimiento para preparar (2-oxo-1,2,3,5-tetrahidroimida- zo(2,1-b)quinazolinil)-oxialquilamidas
US4837239A (en) * 1985-08-23 1989-06-06 Syntex (U.S.A.) Inc. Cardiotonic phosphodiesterase inhibitors complexed with water soluble vitamins
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE59207016D1 (de) 1991-07-05 1996-10-02 Byk Gulden Lomberg Chem Fab Verwendung substituierter pyridazine gegen dermatosen
AU665207B2 (en) * 1991-07-29 1995-12-21 Warner-Lambert Company Quinazoline derivatives as acetylcholinesterase inhibitors
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US7700608B2 (en) 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
US7910597B2 (en) 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US31617A (en) * 1861-03-05 photo-uthcqfupheh
USRE31617E (en) 1972-02-04 1984-06-26 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use
US4313947A (en) * 1974-06-24 1982-02-02 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use
US3983120A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
US3983119A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
US3988340A (en) * 1975-01-23 1976-10-26 Bristol-Myers Company 6-Alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]quinazolin-2-ones
NZ187452A (en) * 1977-06-10 1980-05-27 Otsuka Pharma Co Ltd N- substituted-aminocarbonylpropoxy-carbostyrils and their preparation
NL7807507A (nl) * 1977-07-25 1979-01-29 Hoffmann La Roche Tricyclische verbindingen.
JPS54163825A (en) * 1978-06-15 1979-12-26 Otsuka Pharma Co Ltd Phosphoesterase inhibitor
US4208521A (en) * 1978-07-31 1980-06-17 Bristol-Myers Company Process for the preparation of imidazo[2,1-b]quinazolinones
US4551459A (en) * 1983-02-16 1985-11-05 Syntex (U.S.A.) Inc. Method of treating heart failure using (2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-b]quinazolinyl)oxyalkylamides
US4490371A (en) * 1983-02-16 1984-12-25 Syntex (U.S.A.) Inc. N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
JPS604186A (ja) * 1983-06-21 1985-01-10 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン化合物
ES8607299A1 (es) * 1984-02-15 1986-06-01 Syntex Inc Procedimiento para preparar (2-oxo-1,2,3,5-tetrahidroimida- zo(2,1-b)quinazolinil)-oxialquilamidas

Also Published As

Publication number Publication date
HU191316B (en) 1987-02-27
AU3875485A (en) 1985-08-22
FI850618A0 (fi) 1985-02-14
NO850564L (no) 1985-08-16
AU581205B2 (en) 1989-02-16
ZA851131B (en) 1986-09-24
HUT36122A (en) 1985-08-28
ES549920A0 (es) 1986-04-16
FI81578B (fi) 1990-07-31
ES540403A0 (es) 1986-06-01
FI81578C (fi) 1990-11-12
US4690925A (en) 1987-09-01
FI850618L (fi) 1985-08-16
ES8607299A1 (es) 1986-06-01
IL74349A (en) 1988-07-31
ES8606297A1 (es) 1986-04-16
DK69285D0 (da) 1985-02-14
NZ211117A (en) 1987-10-30
NO164654C (no) 1990-10-31
EP0153152A2 (de) 1985-08-28
JPS60193991A (ja) 1985-10-02
NO164654B (no) 1990-07-23
HU193409B (en) 1987-10-28
EP0153152A3 (de) 1987-07-15
IL74349A0 (en) 1985-05-31
CA1254557A (en) 1989-05-23

Similar Documents

Publication Publication Date Title
DK268285D0 (da) Dialkoxypyridinderivater
DK35785A (da) Tetrahydrocarbazolonderivater
DK243985A (da) Aminoalkylphenoxyderivater
DE3463503D1 (de) Sulfonamido-benzamide derivatives
DE3566887D1 (de) Flavanon derivatives
DK69285D0 (da) Tetrahydroimidazolderivater
DK501085A (da) Substituerede benzimidazolderivater
DK524585A (da) Cholecalciferolderivater
DK460785D0 (da) Substituerede furanylderivater
DK443685A (da) Pirimidinderivater
DK109186D0 (da) Dihydropyridazinonderivater
DK320585A (da) Fluorallylaminderivater
ES539508A0 (es) Derivados de androsteno nuevos
DK514585D0 (da) Aminoethylanilinderivater
DK340485A (da) Phenylnonatetraensyrederivater
DK491786D0 (da) Dichloranilinderivater
DK556386A (da) Quinilinderivater
DE3565100D1 (de) Cycloalkane-indene-carboximidamide derivatives
DK267190A (da) 13-substitueret-5-ketomilbemycinderivater
DK317985A (da) Aminoeburnancarboxylsyrederivater
DK303886A (da) Secocanthinderivater
DE3662889D1 (de) Tetrahydrofurancarboxylic-acid derivatives
DK318085D0 (da) Nitroapovincaminsyrederivater
DK54085D0 (da) Phenylpropargylaminderivater
DE3564269D1 (de) Eburnane derivatives

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment