DK678987A - Kumaranderivater samt fremstilling og brug deraf - Google Patents

Kumaranderivater samt fremstilling og brug deraf

Info

Publication number
DK678987A
DK678987A DK678987A DK678987A DK678987A DK 678987 A DK678987 A DK 678987A DK 678987 A DK678987 A DK 678987A DK 678987 A DK678987 A DK 678987A DK 678987 A DK678987 A DK 678987A
Authority
DK
Denmark
Prior art keywords
couman
derivatives
manufacturing
couman derivatives
Prior art date
Application number
DK678987A
Other languages
English (en)
Other versions
DK678987D0 (da
Inventor
Shinji Terao
Yoshitaka Maki
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK678987D0 publication Critical patent/DK678987D0/da
Publication of DK678987A publication Critical patent/DK678987A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK678987A 1986-12-27 1987-12-22 Kumaranderivater samt fremstilling og brug deraf DK678987A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31338086 1986-12-27
JP23549187 1987-09-18

Publications (2)

Publication Number Publication Date
DK678987D0 DK678987D0 (da) 1987-12-22
DK678987A true DK678987A (da) 1988-06-28

Family

ID=26532158

Family Applications (1)

Application Number Title Priority Date Filing Date
DK678987A DK678987A (da) 1986-12-27 1987-12-22 Kumaranderivater samt fremstilling og brug deraf

Country Status (9)

Country Link
US (1) US4857516A (da)
EP (1) EP0273647B1 (da)
KR (1) KR880007505A (da)
AU (1) AU605818B2 (da)
CA (1) CA1325635C (da)
DE (1) DE3777366D1 (da)
DK (1) DK678987A (da)
HU (1) HU206332B (da)
PT (1) PT86459B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366986A (en) * 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5173499A (en) * 1988-04-15 1992-12-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
JP2855340B2 (ja) * 1988-06-10 1999-02-10 武田薬品工業株式会社 2―置換クマラン誘導体
JP2855341B2 (ja) * 1988-06-10 1999-02-10 武田薬品工業株式会社 新規2―置換クマラン誘導体
IT1229482B (it) * 1988-08-01 1991-09-03 Foscama Biomed Chim Farma Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici.
US4978679A (en) * 1989-09-25 1990-12-18 Merck & Co., Inc. 6- and/or 7-substituted-1,2,3,4,4A,9B-hexahydro-8-hydroxydibenzofuran-3-ols as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
DE4027573A1 (de) * 1990-08-31 1992-03-05 Basf Ag Neue 2,3-dihydrobenzofurane und verfahren zu ihrer herstellung
IE68675B1 (en) * 1990-11-01 1996-07-10 Takeda Chemical Industries Ltd Aminocoumaran derivatives their production and use
FR2679132B1 (fr) * 1991-07-17 1993-10-15 Oreal Utilisation de derives du benzofuranne dans des compositions cosmetiques ou dermatologiques, comme agents depigmentants.
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5244917A (en) * 1992-06-02 1993-09-14 The Dupont Merck Pharmaceutical Company Substituted naphthofurans as anti-inflammatory agents
TW393475B (en) * 1992-10-16 2000-06-11 Chugai Pharmaceutical Co Ltd 4-alkoxyl-2,6-di-t-butyl phenol derivatives
EP0640609A1 (en) * 1993-08-24 1995-03-01 Ono Pharmaceutical Co., Ltd. Fused phenol derivatives having inhibitory activity on TXA2 synthetase, and 5-lipoxygenase and scavenging activity on oxygen species
US5750564A (en) * 1995-09-12 1998-05-12 Hellberg; Mark Anti-oxidant esters of non-steroidal anti-inflammatory agents
US5618835A (en) * 1996-02-01 1997-04-08 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5686471A (en) * 1996-02-01 1997-11-11 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684041A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
CA2289676A1 (en) * 1997-05-08 1998-11-12 Chugai Seiyaku Kabushiki Kaisha Prophylactic/therapeutic agents for atherosclerosis
US7008950B1 (en) 1997-06-05 2006-03-07 Takeda Chemical Industries, Ltd. Benzofurans as suppressors of neurodegeneration
US6573289B1 (en) 1998-04-23 2003-06-03 Takeda Chemical Industries, Ltd. Naphthalene derivatives, their production and use
WO2000009118A1 (en) * 1998-08-13 2000-02-24 The Wistar Institute Methods for reducing atherosclerotic plaques
AU2004261627C1 (en) 2003-07-28 2009-02-05 Smithkline Beecham Corporation Cycloalkylidene compounds as modulators of estrogen receptor
TWM245915U (en) * 2003-07-30 2004-10-11 Nien Made Entpr Co Ltd Safe release device for curtain string
WO2005030198A1 (ja) * 2003-09-26 2005-04-07 Chugai Seiyaku Kabushiki Kaisha 脂肪肝又は肝疾患を治療するための医薬組成物
CA2589363A1 (en) * 2004-12-13 2006-06-22 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2421811A (en) * 1939-07-14 1947-06-10 Univ Minnesota Process for producing chroman compounds
CA1281325C (en) * 1984-06-20 1991-03-12 Patrice C. Belanger Benzofuran derivatives
EP0314852B1 (de) * 1987-11-06 1993-11-18 Ciba-Geigy Ag Verfahren zur Synthese von 1-substituierten Imidazol-5-carbonsäuren und -carbonsäure-derivaten

Also Published As

Publication number Publication date
CA1325635C (en) 1993-12-28
EP0273647A1 (en) 1988-07-06
AU605818B2 (en) 1991-01-24
AU8304087A (en) 1988-06-30
KR880007505A (ko) 1988-08-27
DE3777366D1 (de) 1992-04-16
PT86459B (pt) 1990-11-20
EP0273647B1 (en) 1992-03-11
HU206332B (en) 1992-10-28
HUT48609A (en) 1989-06-28
DK678987D0 (da) 1987-12-22
PT86459A (en) 1988-01-01
US4857516A (en) 1989-08-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment