DK571476A - Indolderivater deres fremstilling og anvendelse - Google Patents

Indolderivater deres fremstilling og anvendelse

Info

Publication number
DK571476A
DK571476A DK571476A DK571476A DK571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A
Authority
DK
Denmark
Prior art keywords
manufacturing
Prior art date
Application number
DK571476A
Other languages
Danish (da)
English (en)
Inventor
R Lattrell
W Bartmann
J Kaiser
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK571476A publication Critical patent/DK571476A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK571476A 1975-12-19 1976-12-17 Indolderivater deres fremstilling og anvendelse DK571476A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752557341 DE2557341A1 (de) 1975-12-19 1975-12-19 Basisch substituierte indolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DK571476A true DK571476A (da) 1977-06-20

Family

ID=5964904

Family Applications (1)

Application Number Title Priority Date Filing Date
DK571476A DK571476A (da) 1975-12-19 1976-12-17 Indolderivater deres fremstilling og anvendelse

Country Status (22)

Country Link
US (1) US4148895A (fr)
JP (1) JPS5277067A (fr)
AT (1) ATA936176A (fr)
AU (1) AU2070076A (fr)
BE (1) BE849627A (fr)
DE (1) DE2557341A1 (fr)
DK (1) DK571476A (fr)
EG (1) EG12485A (fr)
ES (1) ES454234A1 (fr)
FI (1) FI763622A (fr)
FR (1) FR2335215A1 (fr)
GB (1) GB1573809A (fr)
GR (1) GR61172B (fr)
IL (1) IL51119A0 (fr)
IT (1) IT1065425B (fr)
LU (1) LU76426A1 (fr)
NL (1) NL7614052A (fr)
NO (1) NO764299L (fr)
NZ (1) NZ182908A (fr)
PT (1) PT65980B (fr)
SE (1) SE7614218L (fr)
ZA (1) ZA767522B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653021A5 (fr) * 1981-04-24 1985-12-13 Delalande Sa Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
US4588740A (en) * 1982-12-07 1986-05-13 Smithkline Beckman Corporation Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
DE3445377A1 (de) * 1983-12-23 1985-07-04 Sandoz-Patent-GmbH, 7850 Lörrach Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen
FR2578842B1 (fr) * 1985-03-15 1987-04-10 Rhone Poulenc Sante Nouveaux derives de la pyrrolo(1,2-a) azepinone, leur preparation et les compositions pharmaceutiques qui les contiennent
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
US5004812A (en) * 1987-06-26 1991-04-02 E. I. Du Pont De Nemours And Company Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus
US5254552A (en) * 1988-05-24 1993-10-19 American Home Products Corporation Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity
IL114690A (en) * 1990-06-07 1997-02-18 Wellcome Found Antimigraine oxazolidinone substituted indole derivatives
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5284862A (en) * 1991-03-18 1994-02-08 Warner-Lambert Company Derivatives of 2-carboxyindoles having pharmaceutical activity
JP3140155B2 (ja) * 1992-03-09 2001-03-05 杏林製薬株式会社 N,n’−ジ置換アミド誘導体
ES2063700B1 (es) * 1993-04-28 1995-07-16 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
JP2000507556A (ja) * 1996-03-28 2000-06-20 スミスクライン・ビーチャム・コーポレイション ケモカインのカルボン酸インドール阻害剤
WO1999020621A1 (fr) * 1997-10-22 1999-04-29 Eli Lilly And Company ARYLPIPERAZINES AGISSANT COMME INHIBITEURS DE LA REABSORPTION DE SEROTONINE ET COMME ANTAGONISTES DE 5-HT¿1Dα?
JP2003040866A (ja) * 2001-07-31 2003-02-13 Nippon Kayaku Co Ltd N置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤
BRPI0414136A (pt) * 2003-09-04 2006-10-31 Aventis Pharma Inc indóis substituìdos como inibidores de poli(adp-ribose) polimerase (parp)
US8604031B2 (en) * 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors
US7858666B2 (en) 2007-06-08 2010-12-28 Mannkind Corporation IRE-1α inhibitors
AU2009210297B2 (en) * 2008-01-31 2013-11-21 Sanofi Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals
AU2011210765A1 (en) 2010-01-28 2012-09-13 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
ES2724531T3 (es) 2011-05-12 2019-09-11 Proteostasis Therapeutics Inc Reguladores de proteostasis
WO2014116228A1 (fr) 2013-01-25 2014-07-31 President And Fellows Of Harvard College Inhibiteurs de l'usp14 utilisables en vue du traitement ou de la prévention d'infections virales
WO2015073528A1 (fr) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Composés renforçant l'activité des protéasomes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320278A (en) * 1965-06-30 1967-05-16 Merck & Co Inc Alpha-(2-amino)-3-indolyl lower aliphatic acid derivatives
US3847920A (en) * 1973-05-17 1974-11-12 Warner Lambert Co 3-substituted pyrimido(4,5-b)indoles
US3980668A (en) * 1974-09-18 1976-09-14 Bristol-Myers Company Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides

Also Published As

Publication number Publication date
JPS5277067A (en) 1977-06-29
FR2335215A1 (fr) 1977-07-15
NL7614052A (nl) 1977-06-21
GB1573809A (en) 1980-08-28
LU76426A1 (fr) 1977-07-05
ZA767522B (en) 1977-11-30
IT1065425B (it) 1985-02-25
AU2070076A (en) 1978-06-22
IL51119A0 (en) 1977-02-28
BE849627A (fr) 1977-06-20
DE2557341A1 (de) 1977-06-30
EG12485A (en) 1981-06-30
NO764299L (fr) 1977-06-21
US4148895A (en) 1979-04-10
ATA936176A (de) 1980-01-15
FI763622A (fr) 1977-06-20
PT65980B (de) 1978-07-05
ES454234A1 (es) 1977-12-16
PT65980A (de) 1977-01-01
NZ182908A (en) 1979-08-31
SE7614218L (sv) 1977-06-20
GR61172B (en) 1978-10-03

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Legal Events

Date Code Title Description
ATS Application withdrawn