DK571476A - Indolderivater deres fremstilling og anvendelse - Google Patents
Indolderivater deres fremstilling og anvendelseInfo
- Publication number
- DK571476A DK571476A DK571476A DK571476A DK571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A DK 571476 A DK571476 A DK 571476A
- Authority
- DK
- Denmark
- Prior art keywords
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752557341 DE2557341A1 (de) | 1975-12-19 | 1975-12-19 | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
DK571476A true DK571476A (da) | 1977-06-20 |
Family
ID=5964904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK571476A DK571476A (da) | 1975-12-19 | 1976-12-17 | Indolderivater deres fremstilling og anvendelse |
Country Status (22)
Country | Link |
---|---|
US (1) | US4148895A (fr) |
JP (1) | JPS5277067A (fr) |
AT (1) | ATA936176A (fr) |
AU (1) | AU2070076A (fr) |
BE (1) | BE849627A (fr) |
DE (1) | DE2557341A1 (fr) |
DK (1) | DK571476A (fr) |
EG (1) | EG12485A (fr) |
ES (1) | ES454234A1 (fr) |
FI (1) | FI763622A (fr) |
FR (1) | FR2335215A1 (fr) |
GB (1) | GB1573809A (fr) |
GR (1) | GR61172B (fr) |
IL (1) | IL51119A0 (fr) |
IT (1) | IT1065425B (fr) |
LU (1) | LU76426A1 (fr) |
NL (1) | NL7614052A (fr) |
NO (1) | NO764299L (fr) |
NZ (1) | NZ182908A (fr) |
PT (1) | PT65980B (fr) |
SE (1) | SE7614218L (fr) |
ZA (1) | ZA767522B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH653021A5 (fr) * | 1981-04-24 | 1985-12-13 | Delalande Sa | Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant. |
JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
US4588740A (en) * | 1982-12-07 | 1986-05-13 | Smithkline Beckman Corporation | Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones |
DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
FR2578842B1 (fr) * | 1985-03-15 | 1987-04-10 | Rhone Poulenc Sante | Nouveaux derives de la pyrrolo(1,2-a) azepinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
DE3531658A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel |
US5004812A (en) * | 1987-06-26 | 1991-04-02 | E. I. Du Pont De Nemours And Company | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus |
US5254552A (en) * | 1988-05-24 | 1993-10-19 | American Home Products Corporation | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
IL114690A (en) * | 1990-06-07 | 1997-02-18 | Wellcome Found | Antimigraine oxazolidinone substituted indole derivatives |
US5102889B1 (en) * | 1990-09-27 | 1993-05-11 | 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds | |
US5229517A (en) * | 1990-09-27 | 1993-07-20 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds |
US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
JP3140155B2 (ja) * | 1992-03-09 | 2001-03-05 | 杏林製薬株式会社 | N,n’−ジ置換アミド誘導体 |
ES2063700B1 (es) * | 1993-04-28 | 1995-07-16 | Vita Invest Sa | Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan. |
JP2000507556A (ja) * | 1996-03-28 | 2000-06-20 | スミスクライン・ビーチャム・コーポレイション | ケモカインのカルボン酸インドール阻害剤 |
WO1999020621A1 (fr) * | 1997-10-22 | 1999-04-29 | Eli Lilly And Company | ARYLPIPERAZINES AGISSANT COMME INHIBITEURS DE LA REABSORPTION DE SEROTONINE ET COMME ANTAGONISTES DE 5-HT¿1Dα? |
JP2003040866A (ja) * | 2001-07-31 | 2003-02-13 | Nippon Kayaku Co Ltd | N置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤 |
BRPI0414136A (pt) * | 2003-09-04 | 2006-10-31 | Aventis Pharma Inc | indóis substituìdos como inibidores de poli(adp-ribose) polimerase (parp) |
US8604031B2 (en) * | 2006-05-18 | 2013-12-10 | Mannkind Corporation | Intracellular kinase inhibitors |
US7858666B2 (en) | 2007-06-08 | 2010-12-28 | Mannkind Corporation | IRE-1α inhibitors |
AU2009210297B2 (en) * | 2008-01-31 | 2013-11-21 | Sanofi | Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals |
AU2011210765A1 (en) | 2010-01-28 | 2012-09-13 | President And Fellows Of Harvard College | Compositions and methods for enhancing proteasome activity |
ES2724531T3 (es) | 2011-05-12 | 2019-09-11 | Proteostasis Therapeutics Inc | Reguladores de proteostasis |
WO2014116228A1 (fr) | 2013-01-25 | 2014-07-31 | President And Fellows Of Harvard College | Inhibiteurs de l'usp14 utilisables en vue du traitement ou de la prévention d'infections virales |
WO2015073528A1 (fr) | 2013-11-12 | 2015-05-21 | Proteostasis Therapeutics, Inc. | Composés renforçant l'activité des protéasomes |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3320278A (en) * | 1965-06-30 | 1967-05-16 | Merck & Co Inc | Alpha-(2-amino)-3-indolyl lower aliphatic acid derivatives |
US3847920A (en) * | 1973-05-17 | 1974-11-12 | Warner Lambert Co | 3-substituted pyrimido(4,5-b)indoles |
US3980668A (en) * | 1974-09-18 | 1976-09-14 | Bristol-Myers Company | Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides |
-
1975
- 1975-12-19 DE DE19752557341 patent/DE2557341A1/de not_active Withdrawn
-
1976
- 1976-12-14 ES ES454234A patent/ES454234A1/es not_active Expired
- 1976-12-16 US US05/751,084 patent/US4148895A/en not_active Expired - Lifetime
- 1976-12-16 FI FI763622A patent/FI763622A/fi not_active Application Discontinuation
- 1976-12-17 DK DK571476A patent/DK571476A/da not_active Application Discontinuation
- 1976-12-17 SE SE7614218A patent/SE7614218L/xx unknown
- 1976-12-17 NL NL7614052A patent/NL7614052A/xx not_active Application Discontinuation
- 1976-12-17 NO NO764299A patent/NO764299L/no unknown
- 1976-12-17 IL IL51119A patent/IL51119A0/xx unknown
- 1976-12-17 AT AT936176A patent/ATA936176A/de not_active Application Discontinuation
- 1976-12-17 ZA ZA767522A patent/ZA767522B/xx unknown
- 1976-12-17 NZ NZ182908A patent/NZ182908A/xx unknown
- 1976-12-17 AU AU20700/76A patent/AU2070076A/en not_active Expired
- 1976-12-17 LU LU76426A patent/LU76426A1/xx unknown
- 1976-12-17 IT IT30581/76A patent/IT1065425B/it active
- 1976-12-17 PT PT65980A patent/PT65980B/pt unknown
- 1976-12-18 GR GR52437A patent/GR61172B/el unknown
- 1976-12-18 JP JP51151502A patent/JPS5277067A/ja active Pending
- 1976-12-18 EG EG772/76A patent/EG12485A/xx active
- 1976-12-20 FR FR7638399A patent/FR2335215A1/fr not_active Withdrawn
- 1976-12-20 BE BE173448A patent/BE849627A/fr unknown
- 1976-12-20 GB GB53125/76A patent/GB1573809A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5277067A (en) | 1977-06-29 |
FR2335215A1 (fr) | 1977-07-15 |
NL7614052A (nl) | 1977-06-21 |
GB1573809A (en) | 1980-08-28 |
LU76426A1 (fr) | 1977-07-05 |
ZA767522B (en) | 1977-11-30 |
IT1065425B (it) | 1985-02-25 |
AU2070076A (en) | 1978-06-22 |
IL51119A0 (en) | 1977-02-28 |
BE849627A (fr) | 1977-06-20 |
DE2557341A1 (de) | 1977-06-30 |
EG12485A (en) | 1981-06-30 |
NO764299L (fr) | 1977-06-21 |
US4148895A (en) | 1979-04-10 |
ATA936176A (de) | 1980-01-15 |
FI763622A (fr) | 1977-06-20 |
PT65980B (de) | 1978-07-05 |
ES454234A1 (es) | 1977-12-16 |
PT65980A (de) | 1977-01-01 |
NZ182908A (en) | 1979-08-31 |
SE7614218L (sv) | 1977-06-20 |
GR61172B (en) | 1978-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |