DK571088A - Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester - Google Patents
Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylesterInfo
- Publication number
- DK571088A DK571088A DK571088A DK571088A DK571088A DK 571088 A DK571088 A DK 571088A DK 571088 A DK571088 A DK 571088A DK 571088 A DK571088 A DK 571088A DK 571088 A DK571088 A DK 571088A
- Authority
- DK
- Denmark
- Prior art keywords
- aspartyl
- procedure
- preparing alpha
- phenylalanine methylester
- methylester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
- C07C5/02—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by hydrogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25640687 | 1987-10-13 | ||
| JP13841488 | 1988-06-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK571088D0 DK571088D0 (da) | 1988-10-13 |
| DK571088A true DK571088A (da) | 1989-04-14 |
Family
ID=26471445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK571088A DK571088A (da) | 1987-10-13 | 1988-10-13 | Fremgangsmaade til fremstilling af alpha-l-aspartyl-l-phenylalaninmethylester |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4897506A (da) |
| EP (1) | EP0311985B1 (da) |
| KR (1) | KR910001722B1 (da) |
| AU (1) | AU600176B2 (da) |
| BR (1) | BR8805255A (da) |
| CA (1) | CA1303293C (da) |
| DE (1) | DE3888781T2 (da) |
| DK (1) | DK571088A (da) |
| NO (1) | NO884545L (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5591886A (en) * | 1990-11-05 | 1997-01-07 | Mitsui Toatsu Chemicals, Incorporated | Process for the crystallizing L-α-aspartyl-L-phenylalanine methyl ester from the solution |
| JP2946853B2 (ja) * | 1991-05-09 | 1999-09-06 | 味の素株式会社 | アスパルテームの晶析法 |
| US6238711B1 (en) | 1998-11-25 | 2001-05-29 | Wm. Wrigley Jr. Company | Chewing gum with increased flavor release using an aliginate material and method of making |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3786039A (en) * | 1969-04-30 | 1974-01-15 | Ajinomoto Kk | Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters |
| US3761288A (en) * | 1970-07-16 | 1973-09-25 | Gen Foods Corp | Method for making a low calorie sweetening composition |
| US3753739A (en) * | 1970-11-05 | 1973-08-21 | Alberto Culver Co | Low calorie dry sweetener composition |
| US4029701A (en) * | 1972-03-30 | 1977-06-14 | General Foods Corporation | Sweetening with hydrohalide salts of dipeptide sweeteners |
| US3971857A (en) * | 1973-11-21 | 1976-07-27 | General Foods Corporation | Multifunctional sweetening composition |
| US3962468A (en) * | 1974-03-07 | 1976-06-08 | General Foods Corporation | Spray-dried L-aspartic acid derivatives |
| US4465694A (en) * | 1980-12-10 | 1984-08-14 | Ajinomoto Company, Incorporated | Dipeptide sweetening composition |
| US4448716A (en) * | 1982-03-04 | 1984-05-15 | G. D. Searle & Co. | Dipeptide sweetener-metal complexes |
| EP0101756A1 (de) * | 1982-08-31 | 1984-03-07 | Chimicasa Gmbh | Wasserlösliche Süssungstablette |
| JPH0631312B2 (ja) * | 1983-03-18 | 1994-04-27 | 味の素株式会社 | ジペプチド結晶及びその製造方法 |
| JPS59177952A (ja) * | 1983-03-28 | 1984-10-08 | Matsushita Electric Ind Co Ltd | 樹脂封止電子部品 |
| JPS59227849A (ja) * | 1983-06-08 | 1984-12-21 | Ajinomoto Co Inc | Ｌ―α―アスパルチル―Ｌ―フェニルアラニンメチルエステル束状晶の晶析分離法 |
-
1988
- 1988-10-05 AU AU23471/88A patent/AU600176B2/en not_active Ceased
- 1988-10-11 EP EP88116875A patent/EP0311985B1/en not_active Expired - Lifetime
- 1988-10-11 KR KR1019880013258A patent/KR910001722B1/ko not_active IP Right Cessation
- 1988-10-11 DE DE3888781T patent/DE3888781T2/de not_active Expired - Fee Related
- 1988-10-12 US US07/256,838 patent/US4897506A/en not_active Expired - Lifetime
- 1988-10-12 NO NO88884545A patent/NO884545L/no unknown
- 1988-10-12 BR BR8805255A patent/BR8805255A/pt not_active Application Discontinuation
- 1988-10-12 CA CA000580109A patent/CA1303293C/en not_active Expired - Fee Related
- 1988-10-13 DK DK571088A patent/DK571088A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO884545L (no) | 1989-04-14 |
| EP0311985A3 (en) | 1990-08-29 |
| DK571088D0 (da) | 1988-10-13 |
| EP0311985A2 (en) | 1989-04-19 |
| AU600176B2 (en) | 1990-08-02 |
| NO884545D0 (no) | 1988-10-12 |
| US4897506A (en) | 1990-01-30 |
| KR890006547A (ko) | 1989-06-14 |
| DE3888781T2 (de) | 1994-10-27 |
| CA1303293C (en) | 1992-06-09 |
| DE3888781D1 (de) | 1994-05-05 |
| KR910001722B1 (ko) | 1991-03-22 |
| EP0311985B1 (en) | 1994-03-30 |
| BR8805255A (pt) | 1990-05-29 |
| AU2347188A (en) | 1989-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A0 | Application filed | ||
| AHB | Application shelved due to non-payment |