DK551786A - Rekombinant-dna-sekvens, der koder for aminosyresekvenser i et toksin, expressionssystem omfattende samme og vaertsceller transformeret hermed - Google Patents

Rekombinant-dna-sekvens, der koder for aminosyresekvenser i et toksin, expressionssystem omfattende samme og vaertsceller transformeret hermed

Info

Publication number
DK551786A
DK551786A DK551786A DK551786A DK551786A DK 551786 A DK551786 A DK 551786A DK 551786 A DK551786 A DK 551786A DK 551786 A DK551786 A DK 551786A DK 551786 A DK551786 A DK 551786A
Authority
DK
Denmark
Prior art keywords
toxin
amino acid
acid sequences
dna sequence
host cells
Prior art date
Application number
DK551786A
Other languages
English (en)
Other versions
DK551786D0 (da
Inventor
Jr Michael Piatak
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK551786D0 publication Critical patent/DK551786D0/da
Publication of DK551786A publication Critical patent/DK551786A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK551786A 1986-03-07 1986-11-18 Rekombinant-dna-sekvens, der koder for aminosyresekvenser i et toksin, expressionssystem omfattende samme og vaertsceller transformeret hermed DK551786A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83758386A 1986-03-07 1986-03-07

Publications (2)

Publication Number Publication Date
DK551786D0 DK551786D0 (da) 1986-11-18
DK551786A true DK551786A (da) 1987-09-08

Family

ID=25274881

Family Applications (1)

Application Number Title Priority Date Filing Date
DK551786A DK551786A (da) 1986-03-07 1986-11-18 Rekombinant-dna-sekvens, der koder for aminosyresekvenser i et toksin, expressionssystem omfattende samme og vaertsceller transformeret hermed

Country Status (9)

Country Link
EP (2) EP0237676B1 (da)
JP (2) JP3010360B2 (da)
AT (1) ATE169672T1 (da)
AU (1) AU601956B2 (da)
CA (1) CA1324095C (da)
DE (1) DE3650692T2 (da)
DK (1) DK551786A (da)
FI (1) FI864626A (da)
NO (1) NO864986L (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689401A (en) * 1986-03-06 1987-08-25 Cetus Corporation Method of recovering microbially produced recombinant ricin toxin a chain
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography
WO1989004839A1 (en) * 1987-11-24 1989-06-01 Genetics Institute, Inc. Improved ricin molecules and ricin toxin conjugates
WO1991006658A2 (en) * 1989-10-24 1991-05-16 Cetus Corporation Infective protein delivery system
GB2253210B (en) * 1991-02-26 1995-06-07 Ici Plc Soluble heterologous polypeptide produced by culture of recombinant microorganisms
US5888814A (en) * 1994-06-06 1999-03-30 Chiron Corporation Recombinant host cells encoding TNF proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711844A (en) * 1983-03-09 1987-12-08 Cetus Corporation Modified signal peptides
JP2521657B2 (ja) * 1983-07-15 1996-08-07 インペリアル・ケミカル・インダストリーズ・ピーエルシー 組換ｄｎａ分子及びこれを含有する形質転換宿主細胞
EP0335476A3 (en) * 1984-02-08 1989-12-13 Cetus Corporation Recombinant methods for the production of ricin a, ricin b, ricin or diphtheria toxin (dt)a or ab' fragment, suitable hosts and vectors therefor, and conjugates comprising ricin toxin a chain or diphtheria toxin
GB8417915D0 (en) * 1984-07-13 1984-08-15 Ici Plc Microorganisms

Also Published As

Publication number Publication date
JPS62232387A (ja) 1987-10-12
NO864986D0 (no) 1986-12-10
EP0866128A2 (en) 1998-09-23
EP0237676A2 (en) 1987-09-23
DK551786D0 (da) 1986-11-18
ATE169672T1 (de) 1998-08-15
AU6511986A (en) 1987-09-10
EP0237676B1 (en) 1998-08-12
EP0237676A3 (en) 1989-03-29
FI864626A0 (fi) 1986-11-13
DE3650692D1 (de) 1998-09-17
JP3005621B2 (ja) 2000-01-31
EP0866128A3 (en) 1998-12-16
AU601956B2 (en) 1990-09-27
FI864626A (fi) 1987-09-08
CA1324095C (en) 1993-11-09
JP3010360B2 (ja) 2000-02-21
NO864986L (no) 1987-09-08
DE3650692T2 (de) 1999-04-22
JPH10127295A (ja) 1998-05-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment