DK550188A - Antigestagen- og antioestrogenvirksomme forbindelser til behandling af hormonafhaengige tumorer - Google Patents

Antigestagen- og antioestrogenvirksomme forbindelser til behandling af hormonafhaengige tumorer

Info

Publication number
DK550188A
DK550188A DK550188A DK550188A DK550188A DK 550188 A DK550188 A DK 550188A DK 550188 A DK550188 A DK 550188A DK 550188 A DK550188 A DK 550188A DK 550188 A DK550188 A DK 550188A
Authority
DK
Denmark
Prior art keywords
treatment
tumors
hormonode
tended
stage
Prior art date
Application number
DK550188A
Other languages
Danish (da)
English (en)
Other versions
DK550188D0 (da
Inventor
Martin Schneider
Walter Elger
Sibylle Beier
Marianne Faehnrich
Beate Kosub
Krzysztof Chwalisz
Syed Hamiduddin Hasan
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK550188D0 publication Critical patent/DK550188D0/da
Publication of DK550188A publication Critical patent/DK550188A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK550188A 1987-10-01 1988-09-30 Antigestagen- og antioestrogenvirksomme forbindelser til behandling af hormonafhaengige tumorer DK550188A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873733478 DE3733478A1 (de) 1987-10-01 1987-10-01 Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore

Publications (2)

Publication Number Publication Date
DK550188D0 DK550188D0 (da) 1988-09-30
DK550188A true DK550188A (da) 1989-04-02

Family

ID=6337559

Family Applications (2)

Application Number Title Priority Date Filing Date
DK550188A DK550188A (da) 1987-10-01 1988-09-30 Antigestagen- og antioestrogenvirksomme forbindelser til behandling af hormonafhaengige tumorer
DK550088A DK550088A (da) 1987-10-01 1988-09-30 Antigestagen- og antioestrogenvirksomme forbindelser til foedselsindledning og svangerskabsforebyggelse samt til behandling af gynaekologiske forstyrrelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK550088A DK550088A (da) 1987-10-01 1988-09-30 Antigestagen- og antioestrogenvirksomme forbindelser til foedselsindledning og svangerskabsforebyggelse samt til behandling af gynaekologiske forstyrrelser

Country Status (14)

Country Link
US (2) US4888331A (enExample)
EP (1) EP0310541B1 (enExample)
JP (2) JP2656958B2 (enExample)
AT (2) ATE106730T1 (enExample)
AU (2) AU624082B2 (enExample)
CA (2) CA1329126C (enExample)
DE (3) DE3733478A1 (enExample)
DK (2) DK550188A (enExample)
ES (2) ES2055745T3 (enExample)
GR (1) GR3007225T3 (enExample)
IE (2) IE66335B1 (enExample)
IL (2) IL87885A (enExample)
PH (1) PH26774A (enExample)
ZA (2) ZA887379B (enExample)

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FR2654337B1 (fr) * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
DE4329344A1 (de) * 1993-08-27 1995-03-02 Schering Ag Progesteronantagonistisch- und antiöstrogen wirksame Verbindungen für die Behandlung des Leiomyomata uteri
DE4335876A1 (de) * 1993-10-17 1995-04-20 Schering Ag Kombination von Progesteronantagonisten und Antiöstrogenen mit partialer agonistischer Wirkung für die Hormonsubstitutions-Therapie für peri- und postmenopausale Frauen
GB9410533D0 (en) * 1994-05-26 1994-07-13 Lynxvale Ltd In situ hybridisation and immuno-Chemical localisation of a growth factor
DE4426601A1 (de) * 1994-07-27 1996-02-01 Schering Ag Verwendung eines Kombinationsproduktes enthaltend einen kompetitiven Progesteronantagonisten und ein Gestagen zur Herstellung eines Arzneimittels zur Behandlung der Endometriose oder des Leiomyomata uteri
ZA9510926B (en) * 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
DE19706061A1 (de) 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
US6653297B1 (en) * 1997-07-03 2003-11-25 Medical College Of Hampton Roads Control of selective estrogen receptor modulators
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
CN1179753C (zh) * 1999-05-04 2004-12-15 惠氏公司 含有抗孕激素和孕激素的避孕组合物
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6417214B1 (en) * 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6391907B1 (en) * 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6399593B1 (en) * 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
CZ20013912A3 (cs) 1999-05-04 2002-05-15 Strakan Limited Androgen glykosid, sloučenina, testosteron-ß-D-glukosid, 5 alfa-Dihydrotestosteron- 17ß-D-glukosid, farmaceutický prostředek a pouľití sloučeniny
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
AU4980100A (en) * 1999-05-04 2000-11-17 American Home Products Corporation Compositions containing benzimidazolones and progestogens
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
CA2424299A1 (en) * 2000-10-06 2002-04-18 Biomedicines, Inc. Combination therapy for the treatment of estrogen-sensitive disease
US7378406B2 (en) * 2000-10-18 2008-05-27 Schering Ag Use of antiprogestins for prophylaxis and treatment of hormone-dependent diseases
US6599921B2 (en) 2001-02-22 2003-07-29 Nanodesign, Inc. Non-steroidal estrogen receptor ligands
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
US20030013694A1 (en) * 2001-05-25 2003-01-16 Jens Hoffmann Use and compositions of antiprogestins for treatment of prostate diseases
GB0120147D0 (en) * 2001-08-17 2001-10-10 Metris Therapeutics Ltd Treatment method
DE10159217A1 (de) * 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
JP2006521381A (ja) * 2003-02-28 2006-09-21 デック−テク インコーポレーティッド 診断および治療のための共鳴調節物質
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
CA2582669A1 (en) * 2004-10-04 2006-04-20 Wayne State University Use of aromatase inhibitors for the treatment of ectopic pregnancy
WO2008019048A1 (en) * 2006-08-04 2008-02-14 Meditrina Pharmaceuticals Use of aromatase inhibitors for thining the endometrium or treating menorrhagia
US7694688B2 (en) 2007-01-05 2010-04-13 Applied Materials, Inc. Wet clean system design
WO2009075838A2 (en) * 2007-12-10 2009-06-18 Meditrina Pharmaceuticals, Inc. Treatment of menorrhagia with aromatase inhibitor
US20100087402A1 (en) * 2008-09-29 2010-04-08 Vivus, Inc. Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656187A (en) * 1981-08-03 1987-04-07 Eli Lilly And Company Treatment of mammary cancer
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
DE3323321A1 (de) * 1983-06-24 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels
GB8327256D0 (en) * 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
DE3337450A1 (de) * 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
US4775660A (en) * 1984-08-02 1988-10-04 Fernand Labrie Treatment of breast cancer by combination therapy
DE3586053D1 (de) * 1984-08-02 1992-06-17 Labrie Pharmazeutische zusammensetzung fuer die kombinationstherapie von hormonabhaengigem krebs.
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
US4732904A (en) * 1984-12-24 1988-03-22 Morgan Lee R Antiestrogenic hydrazones
DE3533175A1 (de) * 1985-09-13 1987-03-19 Schering Ag Antigestagene zur verschiebung der endometrialen reifung
FR2598083B1 (fr) * 1986-05-05 1989-12-29 Theramex Laboratoire Nouvelles compositions pharmaceutiques a action antiprogesteronique et leur procede d'obtention
DE3633244A1 (de) * 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese

Also Published As

Publication number Publication date
DK550188D0 (da) 1988-09-30
IL87886A0 (en) 1989-03-31
DE3733478A1 (de) 1989-04-13
IE882954L (en) 1989-04-01
US4888331A (en) 1989-12-19
JPH01106822A (ja) 1989-04-24
DE3850026D1 (de) 1995-07-06
CA1329126C (en) 1994-05-03
GR3007225T3 (enExample) 1993-07-30
IL87885A (en) 1993-06-10
IL87885A0 (en) 1989-03-31
DK550088D0 (da) 1988-09-30
AU616208B2 (en) 1991-10-24
ES2055745T3 (es) 1994-09-01
PH26774A (en) 1992-09-28
JP2656958B2 (ja) 1997-09-24
AU624082B2 (en) 1992-06-04
JPH01106823A (ja) 1989-04-24
JP2620333B2 (ja) 1997-06-11
AU2332288A (en) 1989-06-08
IE882953L (en) 1989-04-01
AU2332188A (en) 1989-04-20
CA1330039C (en) 1994-06-07
ZA887379B (en) 1989-05-30
ES2053795T3 (es) 1994-08-01
EP0310541B1 (de) 1992-12-09
ATE83149T1 (de) 1992-12-15
ATE106730T1 (de) 1994-06-15
IE66335B1 (en) 1995-12-27
DE3876582D1 (de) 1993-01-21
IE65165B1 (en) 1995-10-04
EP0310541A1 (de) 1989-04-05
DK550088A (da) 1989-04-02
IL87886A (en) 1993-06-10
ZA887378B (en) 1989-05-30
US5733902A (en) 1998-03-31

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Legal Events

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AHB Application shelved due to non-payment