DK542085A - PROCEDURE FOR PREPARING A CHOLESTEROL SYNTHESIS INHIBITOR - Google Patents

PROCEDURE FOR PREPARING A CHOLESTEROL SYNTHESIS INHIBITOR Download PDF

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Publication number
DK542085A
DK542085A DK542085A DK542085A DK542085A DK 542085 A DK542085 A DK 542085A DK 542085 A DK542085 A DK 542085A DK 542085 A DK542085 A DK 542085A DK 542085 A DK542085 A DK 542085A
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DK
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Prior art keywords
hydrogen atom
compounds
denote
denotes
preparing
Prior art date
Application number
DK542085A
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Danish (da)
Other versions
DK159439B (en
DK542085D0 (en
DK159439C (en
Inventor
A Sato
A Terahara
Y Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from JP55041292A external-priority patent/JPH0692381B2/en
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK542085A publication Critical patent/DK542085A/en
Publication of DK542085D0 publication Critical patent/DK542085D0/en
Publication of DK159439B publication Critical patent/DK159439B/en
Application granted granted Critical
Publication of DK159439C publication Critical patent/DK159439C/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds of the formula I: <IMAGE> in which R1 and R2, which can be identical or different, each denote a hydrogen atom or a methyl group, and R3 denotes a hydrogen atom or a methyl group, with the proviso that R2 and R3 cannot simultaneously be hydrogen atoms, and R2 cannot be an α-methylbutyryl group when R1 denotes a hydrogen atom, and that R1 and R2 do not both denote a hydrogen atom when R3 denotes a methyl group, inhibit the biosynthesis of cholesterol and can therefore be used for treating disorders resulting from large quantities of cholesterol. The compounds in question can be prepared by acylating corresponding compounds in which one or both of the symbols R1 and R2 denote(s) a hydrogen atom, and these compounds can be prepared, for their part, by culturing microorganisms of the genus Monascus.
DK542085A 1980-03-31 1985-11-22 ANALOGY PROCEDURE FOR PREPARING CHOLESTEROL SYNTHESIS INHIBITORS DK159439C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP4129280 1980-03-31
JP55041292A JPH0692381B2 (en) 1980-03-31 1980-03-31 MB-530A derivative
DK145481A DK151273C (en) 1980-03-31 1981-03-31 PROCEDURE FOR THE PREPARATION OF THE CHOLESTEROL BIOSYNTHESE INHIBITOR MB-530A.
DK145481 1981-03-31

Publications (4)

Publication Number Publication Date
DK542085A true DK542085A (en) 1985-11-22
DK542085D0 DK542085D0 (en) 1985-11-22
DK159439B DK159439B (en) 1990-10-15
DK159439C DK159439C (en) 1991-03-25

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ID=26065775

Family Applications (1)

Application Number Title Priority Date Filing Date
DK542085A DK159439C (en) 1980-03-31 1985-11-22 ANALOGY PROCEDURE FOR PREPARING CHOLESTEROL SYNTHESIS INHIBITORS

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DK (1) DK159439C (en)

Also Published As

Publication number Publication date
DK159439B (en) 1990-10-15
DK542085D0 (en) 1985-11-22
DK159439C (en) 1991-03-25

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