DK535287A - Piperidin-4-yl-tetracycliske benzodiazepiner, deres fremstilling og anvendelse - Google Patents

Piperidin-4-yl-tetracycliske benzodiazepiner, deres fremstilling og anvendelse

Info

Publication number
DK535287A
DK535287A DK535287A DK535287A DK535287A DK 535287 A DK535287 A DK 535287A DK 535287 A DK535287 A DK 535287A DK 535287 A DK535287 A DK 535287A DK 535287 A DK535287 A DK 535287A
Authority
DK
Denmark
Prior art keywords
piperidin
preparation
tetracyclic
benzodiazepines
tetracyclic benzodiazepines
Prior art date
Application number
DK535287A
Other languages
English (en)
Other versions
DK535287D0 (da
Inventor
Edward J Glamkowski
Yulin Chiang
Jr Frederick J Ehrgott
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK535287D0 publication Critical patent/DK535287D0/da
Publication of DK535287A publication Critical patent/DK535287A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK535287A 1986-10-14 1987-10-13 Piperidin-4-yl-tetracycliske benzodiazepiner, deres fremstilling og anvendelse DK535287A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/918,242 US4840947A (en) 1986-10-14 1986-10-14 Antiinflammatory and analgesic piperidin-4-yl-tetracyclic benzodiazepines and use thereas

Publications (2)

Publication Number Publication Date
DK535287D0 DK535287D0 (da) 1987-10-13
DK535287A true DK535287A (da) 1988-04-15

Family

ID=25440054

Family Applications (1)

Application Number Title Priority Date Filing Date
DK535287A DK535287A (da) 1986-10-14 1987-10-13 Piperidin-4-yl-tetracycliske benzodiazepiner, deres fremstilling og anvendelse

Country Status (6)

Country Link
US (1) US4840947A (da)
EP (1) EP0265734A1 (da)
JP (1) JPS63104980A (da)
DK (1) DK535287A (da)
IE (1) IE872741L (da)
PT (1) PT85910B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929615A (en) * 1989-06-12 1990-05-29 Hoechst-Roussel Pharmaceuticals Inc. 7H-benzo[b]pyrazino[1,2-d]pyrrolo[3,2,1-jk][1,4]benzodiazepines
FR2725719B1 (fr) * 1994-10-14 1996-12-06 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases iv
FR2746800B1 (fr) * 1996-03-29 1998-06-05 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases 4
BR0308081A (pt) * 2002-03-13 2004-12-21 Janssen Pharmaceutica Nv Inibidores de histona desacetilase
US7550499B2 (en) * 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
EP1954696B1 (en) * 2005-01-19 2011-02-23 Bristol-Myers Squibb Company 2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
WO2007002634A1 (en) * 2005-06-27 2007-01-04 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
EP1896417B1 (en) 2005-06-27 2011-03-23 Bristol-Myers Squibb Company Linear urea mimics antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
DE602006017694D1 (de) * 2005-06-27 2010-12-02 Bristol Myers Squibb Co C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
KR20080027890A (ko) 2005-06-27 2008-03-28 브리스톨-마이어스 스큅 컴퍼니 혈전성 증상의 치료에 유용한 ｐ2ｙ1 수용체의 ｎ-연결헤테로시클릭 길항제
US7960569B2 (en) * 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
CN107298683B (zh) * 2017-07-14 2019-07-30 吉林大学 一种手性苯并二氮杂*化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186199A (en) * 1978-11-02 1980-01-29 American Hoechst Corporation Indolo-,1,2-dihydroindolo-, and 1,2,6,7-tetrahydroindolo [1,7-ab][1,5] benzodiazepines
US4761411A (en) * 1983-05-18 1988-08-02 Hoechst-Roussel Pharmaceuticals Inc. Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses

Also Published As

Publication number Publication date
DK535287D0 (da) 1987-10-13
US4840947A (en) 1989-06-20
PT85910B (pt) 1990-08-31
IE872741L (en) 1988-04-14
PT85910A (en) 1987-11-01
EP0265734A1 (en) 1988-05-04
JPS63104980A (ja) 1988-05-10

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Legal Events

Date Code Title Description
ATS Application withdrawn