DK526476A - Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner - Google Patents

Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner

Info

Publication number
DK526476A
DK526476A DK526476A DK526476A DK526476A DK 526476 A DK526476 A DK 526476A DK 526476 A DK526476 A DK 526476A DK 526476 A DK526476 A DK 526476A DK 526476 A DK526476 A DK 526476A
Authority
DK
Denmark
Prior art keywords
apiro
oner
indoline
cyclopropane
preparing
Prior art date
Application number
DK526476A
Other languages
Danish (da)
English (en)
Inventor
S Noguchi
S Takei
Y Kawano
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK526476A publication Critical patent/DK526476A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/96Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK526476A 1975-11-26 1976-11-23 Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner DK526476A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50141748A JPS5265267A (en) 1975-11-26 1975-11-26 Synthesis of spiro compounds

Publications (1)

Publication Number Publication Date
DK526476A true DK526476A (da) 1977-05-27

Family

ID=15299270

Family Applications (1)

Application Number Title Priority Date Filing Date
DK526476A DK526476A (da) 1975-11-26 1976-11-23 Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner

Country Status (12)

Country Link
US (1) US4105670A (fi)
JP (1) JPS5265267A (fi)
AU (1) AU499472B2 (fi)
BE (1) BE848766A (fi)
CA (1) CA1091656A (fi)
CH (1) CH623811A5 (fi)
DE (1) DE2653477A1 (fi)
DK (1) DK526476A (fi)
FR (1) FR2362125A1 (fi)
GB (1) GB1570596A (fi)
NL (1) NL7613187A (fi)
SE (1) SE421692B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284644A (en) * 1977-01-12 1981-08-18 Takeda Chemical Industries, Ltd. Spirobenzofuranone compounds
US4342779A (en) * 1977-12-27 1982-08-03 Takeda Chemical Industries, Ltd. 7-Acetylspirobenzofuranone compound
JPS5646879A (en) * 1979-09-25 1981-04-28 Takeda Chem Ind Ltd Spiro compound, its preparation, and preventive and remedy for circulatory system disorder
US4330554A (en) * 1980-04-23 1982-05-18 Takeda Chemical Industries, Ltd. Spirobenzofuranone compounds
FR2501676A1 (fr) * 1981-03-11 1982-09-17 Rhone Poulenc Spec Chim Procede de n-alkylation de composes organiques azotes
US7576094B2 (en) * 2004-12-13 2009-08-18 Eli Lilly And Company Spiro derivatives as lipoxygenase inhibitors

Also Published As

Publication number Publication date
SE7613218L (sv) 1977-05-27
US4105670A (en) 1978-08-08
CH623811A5 (fi) 1981-06-30
NL7613187A (nl) 1977-05-31
AU1997476A (en) 1978-06-01
SE421692B (sv) 1982-01-25
CA1091656A (en) 1980-12-16
FR2362125B1 (fi) 1982-07-09
GB1570596A (en) 1980-07-02
BE848766A (fr) 1977-05-25
AU499472B2 (en) 1979-04-26
JPS5265267A (en) 1977-05-30
FR2362125A1 (fr) 1978-03-17
DE2653477A1 (de) 1977-06-08

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