DK526077A - Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler - Google Patents

Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Info

Publication number
DK526077A
DK526077A DK526077A DK526077A DK526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A DK 526077 A DK526077 A DK 526077A
Authority
DK
Denmark
Prior art keywords
organts
callicrain
antiphlogical
bpti
beef
Prior art date
Application number
DK526077A
Other languages
Danish (da)
English (en)
Inventor
E Schnabel
G Reinhardt
H D Schlumberger
E Truscheit
H Tschesche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK526077A publication Critical patent/DK526077A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK526077A 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler DK526077A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762654124 DE2654124A1 (de) 1976-11-29 1976-11-29 Derivate des trypsin-kallikrein-inhibitors aus rinderorganen (bpti) mit proteasenhemmwirkung und antiphlogistischer wirkung, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK526077A true DK526077A (da) 1978-05-30

Family

ID=5994225

Family Applications (1)

Application Number Title Priority Date Filing Date
DK526077A DK526077A (da) 1976-11-29 1977-11-28 Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler

Country Status (10)

Country Link
US (1) US4153687A (ru)
JP (1) JPS5368701A (ru)
BE (1) BE861267A (ru)
DE (1) DE2654124A1 (ru)
DK (1) DK526077A (ru)
ES (1) ES464571A1 (ru)
FR (1) FR2373516A1 (ru)
GB (1) GB1557599A (ru)
NL (1) NL7713091A (ru)
SE (1) SE7713436L (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
RU2054180C1 (ru) * 1991-08-21 1996-02-10 Жирнов Олег Петрович (н/п) Способ лечения вирусных респираторных инфекций
US6057287A (en) * 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
PT737207E (pt) * 1994-01-11 2005-02-28 Dyax Corp Inibidores de plasmina humana derivados de dominios kunitz
ES2227545T3 (es) * 1994-01-11 2005-04-01 Dyax Corporation Proteinas y sus analogos del "dominio de kunitz" inhibidores de calicreina.
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
AU2003243394B2 (en) * 2002-06-07 2008-06-12 Takeda Pharmaceutical Company Limited Prevention and reduction of blood loss
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
EP2386310B1 (en) * 2002-08-28 2018-11-07 Dyax Corp. Methods for preserving organs and tissues
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
JP2009529542A (ja) * 2006-03-10 2009-08-20 ダイアックス コーポレーション エカランチドに関する配合物
US8637454B2 (en) * 2009-01-06 2014-01-28 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
LT3459564T (lt) 2010-01-06 2022-03-10 Takeda Pharmaceutical Company Limited Plazmos kalikreiną surišantys baltymai
KR102320178B1 (ko) 2011-01-06 2021-11-02 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 결합 단백질
AU2012267546B2 (en) 2011-06-10 2015-12-24 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (KLKB1) expression
EP2726153B1 (en) 2011-06-29 2018-03-28 Ionis Pharmaceuticals, Inc. Methods for modulating kallikrein (klkb1) expression
AU2014312196C1 (en) 2013-08-28 2019-12-19 Ionis Pharmaceuticals, Inc. Modulation of prekallikrein (PKK) expression
EP3122782A4 (en) 2014-03-27 2017-09-13 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
EP3862362A3 (en) 2014-05-01 2021-10-27 Ionis Pharmaceuticals, Inc. Conjugates of modified antisense oligonucleotides and their use for modulating pkk expression
AU2016366557B2 (en) 2015-12-11 2024-01-25 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Also Published As

Publication number Publication date
FR2373516A1 (fr) 1978-07-07
US4153687A (en) 1979-05-08
JPS5368701A (en) 1978-06-19
ES464571A1 (es) 1978-09-01
BE861267A (fr) 1978-05-29
FR2373516B1 (ru) 1980-06-13
NL7713091A (nl) 1978-05-31
DE2654124A1 (de) 1978-06-01
GB1557599A (en) 1979-12-12
SE7713436L (sv) 1978-05-30

Similar Documents

Publication Publication Date Title
DK526077A (da) Derivater af trypsin-kallikrein-inhibitoren fra okseorganer (bpti) med proteansehaemmende virkning og antiphlogistsk virknig en fremgangsmaade til fremstilling deraf og deres anvendelse som laegemidler
DK81578A (da) Kassette til affyring af afvaergeprojektiler
DK470277A (da) Liprosomer indeholdende heparin og fremgangsmaade til deres fremstilling
DK142372C (da) Fremgangsmaade til fremstilling af androstan-17-on-derivater
DK188077A (da) Desaminoderivater af en kallikrein trypsininhibitor deres fremstilling og anvendelse
SE433106B (sv) Gaskompressor
DK352377A (da) Azolyl-carboxylsyrederivater fremgangsmade til deres fremstilling og deres anvendelse som fungicider
DK403577A (da) Piperazinylpyridiner til anvendelse som anoreziske midler og fremgangsmaade til fremstilling af disse forbindelser
DK496977A (da) Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
AT370918B (de) Gasentladungslaser
DK148997C (da) Fremgangsmaade til fraktionering af en gasblanding
DK538677A (da) Isoxazolderivater fremgangsmaade til deres fremstilling og midler indeholdende disse forbindelser
DK82177A (da) Fremgangsmade til fremstilling af aminoglycosidderivater mellemprodukter til anvendelse ved denne fremgangsmade og fremgangsmade til deres fresmtilling
DK300977A (da) Fremgangsmade til fremstilling af (3-amino-5-substitueret -6-fluorpyrazinoyl- eller pyrazamido) guanidiner og derivater deraf
DK374177A (da) Fremgangsmaade til deres fremstilling og deres anvendelse som insecticider
DK205377A (da) Prostaglandin-derivater deres fremstilling og anvendelse
DK577377A (da) Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere
DK245077A (da) Fremgangsmade til fremstilling af benzamidderivater
DK15077A (da) Fremgangsmade til kvantitativ bestemmelse af antithrombin iii
DK359577A (da) Fremgangsmade til fremstilling af 2-phenylaminoimidazolin-(2) og syreadditionssalte
DK118177A (da) Fremgangsmade til fremstilling af isobutyramidderivater
DK31977A (da) Fremgangsmade til fremstilling af chromanderivater
DK5777A (da) Acylamino-(alkyl)-benzenderivater samt deres fremstilling og anvendelse
DK255577A (da) Fremgangsmade til fremstilling af 3,4-dihydro-2-methyl-4-oxo-2h-1,2-benzothiazin-3-carboxylsyre1,1-dioxid og dets anvendelse som mellemprodukt
DK161377A (da) Naphtyridinderivater og fremgangsmade til deres fremstilling