DK523376A - Fremgangsmade til fremstilling af o-,n- og carboxyl-derivater af thienamycin - Google Patents

Fremgangsmade til fremstilling af o-,n- og carboxyl-derivater af thienamycin

Info

Publication number
DK523376A
DK523376A DK523376A DK523376A DK523376A DK 523376 A DK523376 A DK 523376A DK 523376 A DK523376 A DK 523376A DK 523376 A DK523376 A DK 523376A DK 523376 A DK523376 A DK 523376A
Authority
DK
Denmark
Prior art keywords
thienamycin
procedure
preparation
carboxyl derivatives
carboxyl
Prior art date
Application number
DK523376A
Other languages
Danish (da)
English (en)
Inventor
B G Christensen
J Hannah
W J Leanzo
R W Ratcliffe
D H M Shih
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK523376A publication Critical patent/DK523376A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK523376A 1975-11-21 1976-11-19 Fremgangsmade til fremstilling af o-,n- og carboxyl-derivater af thienamycin DK523376A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429475A 1975-11-21 1975-11-21

Publications (1)

Publication Number Publication Date
DK523376A true DK523376A (da) 1977-05-22

Family

ID=24543209

Family Applications (1)

Application Number Title Priority Date Filing Date
DK523376A DK523376A (da) 1975-11-21 1976-11-19 Fremgangsmade til fremstilling af o-,n- og carboxyl-derivater af thienamycin

Country Status (8)

Country Link
JP (1) JPS5277082A (show.php)
CH (1) CH633554A5 (show.php)
DE (1) DE2652680A1 (show.php)
DK (1) DK523376A (show.php)
FR (1) FR2332015A1 (show.php)
GB (1) GB1570987A (show.php)
NL (1) NL7612942A (show.php)
SE (1) SE7612961L (show.php)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531141A (en) * 1976-08-17 1978-11-01 Beecham Group Ltd Beta-lactam antibiotics
NL7712092A (nl) * 1976-11-17 1978-05-19 Merck & Co Inc Werkwijze ter bereiding van een nieuw antibiotisch middel.
EP0007152A1 (en) * 1978-04-28 1980-01-23 Beecham Group Plc Beta-lactam antibiotics, preparation and use
DE2963717D1 (en) * 1978-05-06 1982-11-04 Beecham Group Plc Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them
EP0008888B1 (en) * 1978-08-23 1983-09-21 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
EP0044142A1 (en) * 1980-07-03 1982-01-20 Beecham Group Plc Process for the preparation of beta-lactam antibiotics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
DE2652680A1 (de) 1977-06-02
JPS5277082A (en) 1977-06-29
GB1570987A (en) 1980-07-09
FR2332015B1 (show.php) 1978-11-10
SE7612961L (sv) 1977-05-22
JPS61345B2 (show.php) 1986-01-08
FR2332015A1 (fr) 1977-06-17
CH633554A5 (en) 1982-12-15
NL7612942A (nl) 1977-05-24

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