DK50387A - Rekombinant-humant interleukin-2-praeparat og frem-gangsmaade til dets fremstilling - Google Patents
Rekombinant-humant interleukin-2-praeparat og frem-gangsmaade til dets fremstillingInfo
- Publication number
- DK50387A DK50387A DK050387A DK50387A DK50387A DK 50387 A DK50387 A DK 50387A DK 050387 A DK050387 A DK 050387A DK 50387 A DK50387 A DK 50387A DK 50387 A DK50387 A DK 50387A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- humant
- interleukin
- recombinant
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/825,133 US4933433A (en) | 1986-01-31 | 1986-01-31 | Recombinant interleukin-2 composition and process for making it |
Publications (2)
Publication Number | Publication Date |
---|---|
DK50387D0 DK50387D0 (da) | 1987-01-30 |
DK50387A true DK50387A (da) | 1987-08-01 |
Family
ID=25243198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK050387A DK50387A (da) | 1986-01-31 | 1987-01-30 | Rekombinant-humant interleukin-2-praeparat og frem-gangsmaade til dets fremstilling |
Country Status (6)
Country | Link |
---|---|
US (1) | US4933433A (da) |
EP (1) | EP0231132A3 (da) |
JP (1) | JPS62185027A (da) |
CA (1) | CA1281646C (da) |
DK (1) | DK50387A (da) |
IE (1) | IE870239L (da) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5183746A (en) * | 1986-10-27 | 1993-02-02 | Schering Aktiengesellschaft | Formulation processes for pharmaceutical compositions of recombinant β- |
US5037644A (en) * | 1986-10-27 | 1991-08-06 | Cetus Corporation | Pharmaceutical compositions of recombinant interleukin-2 and formulation processes |
US5004605A (en) * | 1987-12-10 | 1991-04-02 | Cetus Corporation | Low pH pharmaceutical compositions of recombinant β-interferon |
US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
FR2684878B1 (fr) * | 1991-12-12 | 1994-02-11 | Roussel Uclaf | Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation. |
DE4239877C1 (de) * | 1992-11-27 | 1994-03-17 | Boehringer Ingelheim Int | Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung |
US6045788A (en) * | 1996-02-28 | 2000-04-04 | Cornell Research Foundation, Inc. | Method of stimulation of immune response with low doses of IL-2 |
US6509313B1 (en) | 1996-02-28 | 2003-01-21 | Cornell Research Foundation, Inc. | Stimulation of immune response with low doses of cytokines |
US6921530B1 (en) | 1999-09-24 | 2005-07-26 | Cornell Research Foundation, Inc. | Low dose IL-2 for potentiation of immunity |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3176491D1 (en) * | 1980-03-05 | 1987-11-26 | Miles Lab | Pasteurized therapeutically active protein compositions |
US4623717A (en) * | 1980-03-05 | 1986-11-18 | Miles Laboratories, Inc. | Pasteurized therapeutically active protein compositions |
US4401756A (en) * | 1981-04-14 | 1983-08-30 | Immunex Corporation | Process for preparing human interleukin 2 |
DE3377363D1 (en) * | 1982-03-31 | 1988-08-18 | Ajinomoto Kk | Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells |
DE3378128D1 (en) * | 1982-04-20 | 1988-11-03 | Sloan Kettering Inst Cancer | Purification of interleukin 2 |
US4490289A (en) * | 1982-09-16 | 1984-12-25 | Hoffmann-La Roche Inc. | Homogeneous human interleukin 2 |
US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
EP0133767B1 (en) * | 1983-08-04 | 1991-04-03 | The Green Cross Corporation | Gamma interferon composition |
AU3235584A (en) * | 1983-08-26 | 1985-02-28 | E.I. Du Pont De Nemours And Company | Expression plasmids for directing overproduction of specific proteins |
JPS60115528A (ja) * | 1983-11-28 | 1985-06-22 | Takeda Chem Ind Ltd | ヒトインタ―ロイキン―2蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物 |
EP0150067A3 (en) * | 1984-01-23 | 1986-12-30 | Takeda Chemical Industries, Ltd. | Stable composition of gamma-interferon |
US4569790A (en) * | 1984-03-28 | 1986-02-11 | Cetus Corporation | Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions |
WO1985004328A1 (en) * | 1984-03-28 | 1985-10-10 | Cetus Corporation | Pharmaceutical compositions of microbially produced interleukin-2 |
US4530787A (en) * | 1984-03-28 | 1985-07-23 | Cetus Corporation | Controlled oxidation of microbially produced cysteine-containing proteins |
US4604377A (en) * | 1984-03-28 | 1986-08-05 | Cetus Corporation | Pharmaceutical compositions of microbially produced interleukin-2 |
DE3583880D1 (de) * | 1984-04-09 | 1991-10-02 | Takeda Chemical Industries Ltd | Stabile interleukin-2-zusammensetzung. |
-
1986
- 1986-01-31 US US06/825,133 patent/US4933433A/en not_active Expired - Fee Related
-
1987
- 1987-01-27 CA CA000528295A patent/CA1281646C/en not_active Expired - Lifetime
- 1987-01-30 EP EP87300817A patent/EP0231132A3/en not_active Withdrawn
- 1987-01-30 DK DK050387A patent/DK50387A/da not_active Application Discontinuation
- 1987-01-30 JP JP62018786A patent/JPS62185027A/ja active Pending
- 1987-01-30 IE IE870239A patent/IE870239L/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK50387D0 (da) | 1987-01-30 |
JPS62185027A (ja) | 1987-08-13 |
EP0231132A3 (en) | 1989-03-15 |
IE870239L (en) | 1987-07-31 |
US4933433A (en) | 1990-06-12 |
EP0231132A2 (en) | 1987-08-05 |
CA1281646C (en) | 1991-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |