DK486088A - Hmg-coa reduktaseinhibitor og fremgangsmaade til fremstilling deraf - Google Patents
Hmg-coa reduktaseinhibitor og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK486088A DK486088A DK486088A DK486088A DK486088A DK 486088 A DK486088 A DK 486088A DK 486088 A DK486088 A DK 486088A DK 486088 A DK486088 A DK 486088A DK 486088 A DK486088 A DK 486088A
- Authority
- DK
- Denmark
- Prior art keywords
- hmg
- preparing
- procedure
- coa reductase
- reductase inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9235387A | 1987-09-02 | 1987-09-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK486088D0 DK486088D0 (da) | 1988-09-01 |
DK486088A true DK486088A (da) | 1989-03-03 |
Family
ID=22232821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK486088A DK486088A (da) | 1987-09-02 | 1988-09-01 | Hmg-coa reduktaseinhibitor og fremgangsmaade til fremstilling deraf |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0306263B1 (da) |
JP (1) | JPH0196151A (da) |
CA (1) | CA1307263C (da) |
DE (1) | DE3869282D1 (da) |
DK (1) | DK486088A (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5001148A (en) * | 1989-06-07 | 1991-03-19 | E. R. Squibb & Sons, Inc. | Mevinic acid derivatives |
DE69008277D1 (de) * | 1989-08-31 | 1994-05-26 | Merck & Co Inc | 7-Subsituierte HMG-CoA-Reduktase-Inhibitoren. |
CN114558618B (zh) * | 2022-01-04 | 2023-10-31 | 山东理工大学 | 一类叠氮-炔环加成多酸基光催化剂的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK149080C (da) * | 1980-06-06 | 1986-07-28 | Sankyo Co | Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre |
US4376863A (en) * | 1981-08-21 | 1983-03-15 | Merck & Co., Inc. | Hypocholesterolemic fermentation products |
JPS5835144A (ja) * | 1981-08-27 | 1983-03-01 | Sankyo Co Ltd | Mb−530b誘導体およびその製造法 |
JPS5889191A (ja) * | 1981-11-20 | 1983-05-27 | Sankyo Co Ltd | 3−ヒドロキシ−ml−236b誘導体の製造法 |
JPS59122483A (ja) * | 1982-12-28 | 1984-07-14 | Nippon Chemiphar Co Ltd | 新規なモナコリン誘導体 |
US4611068A (en) * | 1984-11-19 | 1986-09-09 | Merck Frosst Canada, Inc. | Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein |
PT85109A (en) * | 1986-06-23 | 1987-07-01 | Merck & Co Inc | Process for the preparation of hydroxy-tetrahydropyranone derivatives or corresponding ring opened dihydroxy acids which are hmg-coa reductase inhibitors |
-
1988
- 1988-08-30 EP EP88308010A patent/EP0306263B1/en not_active Expired - Lifetime
- 1988-08-30 DE DE8888308010T patent/DE3869282D1/de not_active Expired - Fee Related
- 1988-08-31 CA CA000576168A patent/CA1307263C/en not_active Expired - Fee Related
- 1988-09-01 DK DK486088A patent/DK486088A/da not_active Application Discontinuation
- 1988-09-02 JP JP63218652A patent/JPH0196151A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0306263A2 (en) | 1989-03-08 |
JPH0196151A (ja) | 1989-04-14 |
EP0306263B1 (en) | 1992-03-18 |
EP0306263A3 (en) | 1989-08-23 |
DK486088D0 (da) | 1988-09-01 |
CA1307263C (en) | 1992-09-08 |
DE3869282D1 (de) | 1992-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |