DK468084A - Substituerede 2(1h)-quinazolinon-1-alkansyrer og -estere, samt fremgangsmaade til fremstilling deraf - Google Patents

Substituerede 2(1h)-quinazolinon-1-alkansyrer og -estere, samt fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK468084A
DK468084A DK468084A DK468084A DK468084A DK 468084 A DK468084 A DK 468084A DK 468084 A DK468084 A DK 468084A DK 468084 A DK468084 A DK 468084A DK 468084 A DK468084 A DK 468084A
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DK
Denmark
Prior art keywords
quinazolinon
esters
substituted
preparing
alkanic acids
Prior art date
Application number
DK468084A
Other languages
Danish (da)
English (en)
Other versions
DK468084D0 (da
Inventor
Victor T Bandurco
Seymour D Levine
Alfonso J Tobia
Dennis M Mulvey
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/537,233 external-priority patent/US4555571A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of DK468084D0 publication Critical patent/DK468084D0/da
Publication of DK468084A publication Critical patent/DK468084A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
DK468084A 1983-09-29 1984-09-28 Substituerede 2(1h)-quinazolinon-1-alkansyrer og -estere, samt fremgangsmaade til fremstilling deraf DK468084A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/537,233 US4555571A (en) 1983-09-29 1983-09-29 Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
US06/627,138 US4656267A (en) 1983-09-29 1984-07-02 Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters

Publications (2)

Publication Number Publication Date
DK468084D0 DK468084D0 (da) 1984-09-28
DK468084A true DK468084A (da) 1985-03-30

Family

ID=27065423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK468084A DK468084A (da) 1983-09-29 1984-09-28 Substituerede 2(1h)-quinazolinon-1-alkansyrer og -estere, samt fremgangsmaade til fremstilling deraf

Country Status (5)

Country Link
US (1) US4656267A (de)
EP (1) EP0138491A3 (de)
DK (1) DK468084A (de)
GR (1) GR80506B (de)
NO (1) NO843909L (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751304A (en) * 1984-09-26 1988-06-14 Ortho Pharmaceutical Corporation Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
EP2147679B1 (de) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Zusammensetzungen für den Blut-Hirn-Schrankentransport
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008011032A1 (en) * 2006-07-17 2008-01-24 Amgen Inc. Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US10111873B1 (en) 2018-01-17 2018-10-30 King Saud University Dihydropyrimidinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2118315C3 (de) * 1970-04-20 1975-04-03 Sumitomo Chemical Co., Ltd., Osaka (Japan) 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4001238A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company 1,3,4-oxadiazole amides
US4146712A (en) * 1976-03-11 1979-03-27 Ciba-Geigy Corporation Process for the manufacture of coumarin dyes
JPS5795966A (en) * 1980-12-04 1982-06-15 Sumitomo Chem Co Ltd Novel 2(1h)-quinazolinone derivative
US4490374A (en) * 1982-09-30 1984-12-25 Ortho Pharmaceutical Corporation 5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use
US4555571A (en) * 1983-09-29 1985-11-26 Ortho Pharmaceutical Corporation Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
US4555570A (en) * 1983-09-29 1985-11-26 Ortho Pharmaceutical Corporation Substituted 4-alkyl-2-(1H) quinazolinone-1-alkanoic acid derivatives

Also Published As

Publication number Publication date
GR80506B (en) 1985-01-30
DK468084D0 (da) 1984-09-28
US4656267A (en) 1987-04-07
EP0138491A3 (de) 1986-01-15
NO843909L (no) 1985-04-01
EP0138491A2 (de) 1985-04-24

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AHB Application shelved due to non-payment