DK45784A - Cyclisk hexapeptid, dets fremstilling og anvendelse - Google Patents

Cyclisk hexapeptid, dets fremstilling og anvendelse Download PDF

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Publication number
DK45784A
DK45784A DK45784A DK45784A DK45784A DK 45784 A DK45784 A DK 45784A DK 45784 A DK45784 A DK 45784A DK 45784 A DK45784 A DK 45784A DK 45784 A DK45784 A DK 45784A
Authority
DK
Denmark
Prior art keywords
manufacturing
aminoacid
carbon atoms
image
general formula
Prior art date
Application number
DK45784A
Other languages
Danish (da)
English (en)
Other versions
DK45784D0 (da
Inventor
Axel Friedrich
Wolfgang Koenig
Volker Teetz
Rolf Geiger
Juergen Kurt Sandow
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK45784D0 publication Critical patent/DK45784D0/da
Publication of DK45784A publication Critical patent/DK45784A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
DK45784A 1983-02-02 1984-02-01 Cyclisk hexapeptid, dets fremstilling og anvendelse DK45784A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833303345 DE3303345A1 (de) 1983-02-02 1983-02-02 Cyclische peptide mit somatostatin-wirkung

Publications (2)

Publication Number Publication Date
DK45784D0 DK45784D0 (da) 1984-02-01
DK45784A true DK45784A (da) 1984-08-03

Family

ID=6189751

Family Applications (1)

Application Number Title Priority Date Filing Date
DK45784A DK45784A (da) 1983-02-02 1984-02-01 Cyclisk hexapeptid, dets fremstilling og anvendelse

Country Status (15)

Country Link
US (1) US4621073A (fr)
EP (1) EP0117447B1 (fr)
JP (1) JPS59141549A (fr)
KR (1) KR850000468A (fr)
AT (1) ATE31314T1 (fr)
AU (1) AU566208B2 (fr)
CA (1) CA1245638A (fr)
DE (2) DE3303345A1 (fr)
DK (1) DK45784A (fr)
ES (1) ES529301A0 (fr)
GR (1) GR79752B (fr)
IE (1) IE56718B1 (fr)
IL (1) IL70848A (fr)
PT (1) PT78046B (fr)
ZA (1) ZA84739B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505897A (en) * 1983-04-18 1985-03-19 The Administrators Of The Tulane Educational Fund Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith
US4612366A (en) * 1985-06-17 1986-09-16 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
US5965694A (en) * 1992-09-01 1999-10-12 The Trustees Of The University Of Pennsylvania Somatostatin mimics and synthetic methods therefor
US5700905A (en) * 1992-09-01 1997-12-23 The Trustees Of The University Of Pennsylvania Synthetic somatostatin mimics
US6001960A (en) * 1992-09-01 1999-12-14 The Trustees Of The University Of Pennsylvania Synthetic somatostatin mimics
GB0318682D0 (en) * 2003-08-08 2003-09-10 Novartis Ag Organic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303583A (en) * 1979-08-13 1981-12-01 American Home Products Corporation 1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
NZ195303A (en) * 1979-10-31 1984-10-19 Merck & Co Inc Cyclic hexapeptide somatostatin analogues,and pharmaceutical compositions
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs

Also Published As

Publication number Publication date
AU566208B2 (en) 1987-10-15
PT78046B (de) 1986-07-15
IL70848A (en) 1987-10-30
DE3468031D1 (en) 1988-01-21
ES8500219A1 (es) 1984-10-01
EP0117447B1 (fr) 1987-12-09
CA1245638A (fr) 1988-11-29
ES529301A0 (es) 1984-10-01
US4621073A (en) 1986-11-04
AU2399784A (en) 1984-08-09
DK45784D0 (da) 1984-02-01
PT78046A (de) 1984-03-01
ATE31314T1 (de) 1987-12-15
EP0117447A1 (fr) 1984-09-05
IE56718B1 (en) 1991-11-20
IL70848A0 (en) 1984-05-31
JPS59141549A (ja) 1984-08-14
GR79752B (fr) 1984-10-31
KR850000468A (ko) 1985-02-27
ZA84739B (en) 1984-09-26
DE3303345A1 (de) 1984-08-02
IE840243L (en) 1984-08-02

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Legal Events

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