DK423084A - 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin b, dens 4ae-epimer og farmaceutisk acceptable salte deraf samt forbindelser til anvendelsen som mellemprodukter ved fremstilling deraf - Google Patents

9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin b, dens 4ae-epimer og farmaceutisk acceptable salte deraf samt forbindelser til anvendelsen som mellemprodukter ved fremstilling deraf Download PDF

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Publication number
DK423084A
DK423084A DK423084A DK423084A DK423084A DK 423084 A DK423084 A DK 423084A DK 423084 A DK423084 A DK 423084A DK 423084 A DK423084 A DK 423084A DK 423084 A DK423084 A DK 423084A
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DK
Denmark
Prior art keywords
homoerythromycin
deoxo
epimer
aza
intermediates
Prior art date
Application number
DK423084A
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English (en)
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DK159450C (da
DK423084D0 (da
DK159450B (da
Inventor
Gene Michael Bright
James Robert Hauske
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of DK423084D0 publication Critical patent/DK423084D0/da
Publication of DK423084A publication Critical patent/DK423084A/da
Publication of DK159450B publication Critical patent/DK159450B/da
Application granted granted Critical
Publication of DK159450C publication Critical patent/DK159450C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK423084A 1983-09-06 1984-09-05 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin b og farmaceutisk acceptable syreadditionssalte deraf samt 9-deoxo-9a-aza-9a-homoerythromycin b til anvendelse som mellemprodukt ved fremstilling deraf DK159450C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52982783A 1983-09-06 1983-09-06
US52982783 1983-09-06

Publications (4)

Publication Number Publication Date
DK423084D0 DK423084D0 (da) 1984-09-05
DK423084A true DK423084A (da) 1985-03-07
DK159450B DK159450B (da) 1990-10-15
DK159450C DK159450C (da) 1991-03-18

Family

ID=24111404

Family Applications (1)

Application Number Title Priority Date Filing Date
DK423084A DK159450C (da) 1983-09-06 1984-09-05 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin b og farmaceutisk acceptable syreadditionssalte deraf samt 9-deoxo-9a-aza-9a-homoerythromycin b til anvendelse som mellemprodukt ved fremstilling deraf

Country Status (9)

Country Link
EP (1) EP0136831B1 (da)
JP (1) JPS6072896A (da)
AT (1) ATE38519T1 (da)
CA (1) CA1239398A (da)
DE (1) DE3475073D1 (da)
DK (1) DK159450C (da)
ES (1) ES535624A0 (da)
GR (1) GR80277B (da)
IE (1) IE57632B1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US6407074B1 (en) 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4382085A (en) * 1982-03-01 1983-05-03 Pfizer Inc. 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
US4496546A (en) * 1982-04-12 1985-01-29 Pfizer Inc. Erythromycin D and esters thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof

Also Published As

Publication number Publication date
EP0136831B1 (en) 1988-11-09
GR80277B (en) 1985-01-04
JPS6072896A (ja) 1985-04-24
EP0136831A2 (en) 1985-04-10
ATE38519T1 (de) 1988-11-15
ES8603506A1 (es) 1985-12-16
DK159450C (da) 1991-03-18
DK423084D0 (da) 1984-09-05
EP0136831A3 (en) 1986-03-19
IE57632B1 (en) 1993-02-10
CA1239398A (en) 1988-07-19
IE842267L (en) 1985-03-06
ES535624A0 (es) 1985-12-16
DK159450B (da) 1990-10-15
DE3475073D1 (en) 1988-12-15

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