DK418986A - Pyrrolobenzimidazoler, pyrrolobenzoxazoler og pyrrolobenzthiazoler, fremgangsmaader til fremstilling heraf og laegemidler med indhold heraf - Google Patents

Pyrrolobenzimidazoler, pyrrolobenzoxazoler og pyrrolobenzthiazoler, fremgangsmaader til fremstilling heraf og laegemidler med indhold heraf Download PDF

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Publication number
DK418986A
DK418986A DK418986A DK418986A DK418986A DK 418986 A DK418986 A DK 418986A DK 418986 A DK418986 A DK 418986A DK 418986 A DK418986 A DK 418986A DK 418986 A DK418986 A DK 418986A
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DK
Denmark
Prior art keywords
pyrrolobenzthiazoles
pyrrolobenzoxazoles
pyrrolobenzimidazoles
procedures
preparation
Prior art date
Application number
DK418986A
Other languages
Danish (da)
English (en)
Other versions
DK418986D0 (da
Inventor
Wolfgang Von Der Saal
Alfred Mertens
Herbert Berger
Bernd Mueller-Beckmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK418986D0 publication Critical patent/DK418986D0/da
Publication of DK418986A publication Critical patent/DK418986A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • External Artificial Organs (AREA)
  • Lubricants (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Indole Compounds (AREA)
DK418986A 1985-09-05 1986-09-02 Pyrrolobenzimidazoler, pyrrolobenzoxazoler og pyrrolobenzthiazoler, fremgangsmaader til fremstilling heraf og laegemidler med indhold heraf DK418986A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853531678 DE3531678A1 (de) 1985-09-05 1985-09-05 Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
DK418986D0 DK418986D0 (da) 1986-09-02
DK418986A true DK418986A (da) 1987-03-06

Family

ID=6280182

Family Applications (1)

Application Number Title Priority Date Filing Date
DK418986A DK418986A (da) 1985-09-05 1986-09-02 Pyrrolobenzimidazoler, pyrrolobenzoxazoler og pyrrolobenzthiazoler, fremgangsmaader til fremstilling heraf og laegemidler med indhold heraf

Country Status (17)

Country Link
US (1) US4730003A (fi)
EP (1) EP0214592B1 (fi)
JP (1) JPS6259279A (fi)
KR (1) KR870003109A (fi)
AT (1) ATE66230T1 (fi)
AU (1) AU584235B2 (fi)
DD (1) DD253821A5 (fi)
DE (2) DE3531678A1 (fi)
DK (1) DK418986A (fi)
ES (1) ES2001774A6 (fi)
FI (1) FI863565A (fi)
GR (1) GR862247B (fi)
HU (1) HU197010B (fi)
IL (1) IL79910A (fi)
NZ (1) NZ217418A (fi)
PT (1) PT83309B (fi)
ZA (1) ZA866704B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3642315A1 (de) * 1986-12-11 1988-06-23 Boehringer Mannheim Gmbh Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
DE3740985A1 (de) * 1987-12-03 1989-06-15 Boehringer Mannheim Gmbh Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation
US4963677A (en) * 1987-12-30 1990-10-16 Orion Corporation Ltd. Heterocyclic lactam compounds
ATE138658T1 (de) * 1987-12-30 1996-06-15 Orion Yhtymae Oy Heterocyclische verbindungen
DE3809868A1 (de) * 1988-03-24 1989-10-05 Boehringer Mannheim Gmbh Neue heterocyclisch substituierte 5,7-dihydro-pyrrolo(3,2-f)benzoxazol-6-one, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
TR200101756T2 (tr) 1998-12-17 2001-10-22 F.Hoffmann-La Roche Ag Protein kinaz inhibitörleri olarak 4,5-pirazinoksindoller.
US6153634A (en) * 1998-12-17 2000-11-28 Hoffmann-La Roche Inc. 4,5-azolo-oxindoles
EP1598353A1 (en) * 2004-05-17 2005-11-23 Boehringer Ingelheim International GmbH Pyrrolobenzimidazolones and their use as antiproliferative agents
CN102140099A (zh) * 2010-02-02 2011-08-03 山东轩竹医药科技有限公司 新的吡啶衍生物
PL3239269T3 (pl) 2014-09-25 2020-12-14 Daikin Industries, Ltd. Kompozycja zawierająca HFC i HFO

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR65025B (en) * 1977-07-21 1980-06-16 Thomae Gmbh Dr K Method for the preparation of new imidazo-isokinolin-diones
DE3410168A1 (de) * 1984-03-20 1985-09-26 Boehringer Mannheim Gmbh, 6800 Mannheim Neue isochinolin-dione, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
PL147842B1 (en) * 1984-05-12 1989-08-31 Method of obtaining novel pyroisobenzimidazoles
US4695571A (en) * 1984-08-24 1987-09-22 Pfizer Inc. Tricyclic oxindole antiinflammatory agents
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3639466A1 (de) * 1986-11-18 1988-05-19 Thomae Gmbh Dr K Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
KR870003109A (ko) 1987-04-15
DE3531678A1 (de) 1987-03-12
JPS6259279A (ja) 1987-03-14
FI863565A0 (fi) 1986-09-04
DK418986D0 (da) 1986-09-02
PT83309A (de) 1986-10-01
DD253821A5 (de) 1988-02-03
NZ217418A (en) 1988-11-29
IL79910A0 (en) 1986-12-31
HUT42770A (en) 1987-08-28
AU584235B2 (en) 1989-05-18
EP0214592B1 (de) 1991-08-14
DE3680845D1 (de) 1991-09-19
FI863565A (fi) 1987-03-06
PT83309B (de) 1988-01-11
US4730003A (en) 1988-03-08
EP0214592A3 (en) 1988-07-06
ATE66230T1 (de) 1991-08-15
IL79910A (en) 1990-02-09
ZA866704B (en) 1987-05-27
ES2001774A6 (es) 1988-06-16
HU197010B (en) 1989-02-28
AU6216586A (en) 1987-03-12
GR862247B (en) 1986-12-31
EP0214592A2 (de) 1987-03-18

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Legal Events

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AHB Application shelved due to non-payment