DK4097117T3 - Fremgangsmåde til fremstilling af nukleinsyreoligomer - Google Patents
Fremgangsmåde til fremstilling af nukleinsyreoligomer Download PDFInfo
- Publication number
- DK4097117T3 DK4097117T3 DK21705632.4T DK21705632T DK4097117T3 DK 4097117 T3 DK4097117 T3 DK 4097117T3 DK 21705632 T DK21705632 T DK 21705632T DK 4097117 T3 DK4097117 T3 DK 4097117T3
- Authority
- DK
- Denmark
- Prior art keywords
- oligomes
- procedure
- production
- nucleic acid
- nucleic
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020012789 | 2020-01-29 | ||
| PCT/JP2021/003351 WO2021153770A1 (en) | 2020-01-29 | 2021-01-29 | Process of preparing nucleic acid oligomer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK4097117T3 true DK4097117T3 (da) | 2024-07-22 |
Family
ID=74626048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK21705632.4T DK4097117T3 (da) | 2020-01-29 | 2021-01-29 | Fremgangsmåde til fremstilling af nukleinsyreoligomer |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12391716B2 (https=) |
| EP (1) | EP4097117B1 (https=) |
| JP (1) | JP7667788B2 (https=) |
| KR (1) | KR20220133919A (https=) |
| CN (1) | CN115003680B (https=) |
| DK (1) | DK4097117T3 (https=) |
| ES (1) | ES2981209T3 (https=) |
| WO (1) | WO2021153770A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114573652B (zh) * | 2022-03-15 | 2025-02-07 | 安徽瑞拜药业有限公司 | 药用核酸合成工艺 |
| CR20250257A (es) | 2022-12-02 | 2025-08-28 | Shanghai Argo Biopharmaceutical Co Ltd | Análogos de ácidos nucleicos bicíclicos abásicos y compuestos oligoméricos preparados a partir de estos |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2005275801B2 (en) * | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| EP2933333B1 (en) | 2010-07-08 | 2018-02-21 | Bonac Corporation | Single-strand nucleic acid molecule for controlling gene expression |
| EP2639307B1 (en) | 2010-08-03 | 2015-03-04 | Bonac Corporation | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton |
| MX370398B (es) | 2011-08-25 | 2019-12-11 | Bonac Corp | Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico. |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| EP3450439B8 (en) | 2016-04-26 | 2021-06-30 | Sumitomo Chemical Company, Limited | Method for producing monomer for single-stranded nucleic acid molecule |
| JPWO2018182008A1 (ja) | 2017-03-31 | 2020-02-06 | 株式会社ボナック | 遺伝子発現制御機能を有する環状型核酸分子 |
| JP7140111B2 (ja) | 2017-05-16 | 2022-09-21 | 日産化学株式会社 | オリゴヌクレオチドの製造方法 |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US20210188895A1 (en) | 2017-10-13 | 2021-06-24 | Bonac Corporation | Single-stranded nucleic acid molecule, and production method therefor |
| KR102670605B1 (ko) | 2018-04-24 | 2024-05-29 | 스미또모 가가꾸 가부시끼가이샤 | 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법 |
| JP7087766B2 (ja) | 2018-07-20 | 2022-06-21 | 日本製鉄株式会社 | 粒度分布定数推定装置、粒度分布定数推定プログラム、及び粒度分布定数推定方法 |
| WO2020236618A1 (en) | 2019-05-17 | 2020-11-26 | Ionis Pharmaceuticals, Inc. | Synthesis of oligomeric compounds comprising phosphorothioate diester and phosphate diester linkages |
| CN113993876B (zh) | 2019-06-11 | 2024-06-14 | 豪夫迈·罗氏有限公司 | 使用改进的氧化方案制备寡核苷酸的方法 |
| EP4098655A4 (en) | 2020-01-29 | 2024-02-28 | Sumitomo Chemical Company, Limited | METHOD FOR PRODUCING NUCLEIC ACID OLIGOMERS |
-
2021
- 2021-01-29 JP JP2022545096A patent/JP7667788B2/ja active Active
- 2021-01-29 ES ES21705632T patent/ES2981209T3/es active Active
- 2021-01-29 US US17/792,484 patent/US12391716B2/en active Active
- 2021-01-29 CN CN202180011006.7A patent/CN115003680B/zh active Active
- 2021-01-29 DK DK21705632.4T patent/DK4097117T3/da active
- 2021-01-29 EP EP21705632.4A patent/EP4097117B1/en active Active
- 2021-01-29 WO PCT/JP2021/003351 patent/WO2021153770A1/en not_active Ceased
- 2021-01-29 KR KR1020227028950A patent/KR20220133919A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230095584A1 (en) | 2023-03-30 |
| JP7667788B2 (ja) | 2025-04-23 |
| JP2023514503A (ja) | 2023-04-06 |
| KR20220133919A (ko) | 2022-10-05 |
| CN115003680B (zh) | 2025-01-28 |
| US12391716B2 (en) | 2025-08-19 |
| EP4097117A1 (en) | 2022-12-07 |
| ES2981209T3 (es) | 2024-10-07 |
| WO2021153770A1 (en) | 2021-08-05 |
| EP4097117B1 (en) | 2024-05-01 |
| CN115003680A (zh) | 2022-09-02 |
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