DK407885A - 7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner - Google Patents

7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner Download PDF

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Publication number
DK407885A
DK407885A DK407885A DK407885A DK407885A DK 407885 A DK407885 A DK 407885A DK 407885 A DK407885 A DK 407885A DK 407885 A DK407885 A DK 407885A DK 407885 A DK407885 A DK 407885A
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DK
Denmark
Prior art keywords
benzimidazol
dialkylamino
hydroxy
ones
ethyl
Prior art date
Application number
DK407885A
Other languages
Danish (da)
English (en)
Other versions
DK407885D0 (da
Inventor
Orum David Stringer
Joseph Weinstock
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK407885D0 publication Critical patent/DK407885D0/da
Publication of DK407885A publication Critical patent/DK407885A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
DK407885A 1984-09-12 1985-09-06 7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner DK407885A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/649,465 US4554287A (en) 1984-09-12 1984-09-12 Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones

Publications (2)

Publication Number Publication Date
DK407885D0 DK407885D0 (da) 1985-09-06
DK407885A true DK407885A (da) 1986-03-13

Family

ID=24604906

Family Applications (1)

Application Number Title Priority Date Filing Date
DK407885A DK407885A (da) 1984-09-12 1985-09-06 7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner

Country Status (12)

Country Link
US (1) US4554287A (ja)
EP (1) EP0175525B1 (ja)
JP (1) JPS6168473A (ja)
AT (1) ATE53025T1 (ja)
AU (1) AU586187B2 (ja)
CA (1) CA1255685A (ja)
DE (1) DE3577849D1 (ja)
DK (1) DK407885A (ja)
ES (1) ES8605491A1 (ja)
GR (1) GR852189B (ja)
PT (1) PT81109B (ja)
ZA (1) ZA856943B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0189473B1 (de) * 1984-08-15 1992-05-27 Schering Aktiengesellschaft Neue dopamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3728695A1 (de) * 1987-08-25 1989-03-09 Schering Ag Neue benzimidazol-derivate
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
CN102124003A (zh) 2008-06-18 2011-07-13 阿斯利康(瑞典)有限公司 作为治疗呼吸系统疾病的β2肾上腺素受体拮抗剂的苯并噁嗪酮衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070478A (en) * 1977-02-17 1978-01-24 Merck & Co., Inc. Benzimidazole substituted alanines
US4179505A (en) * 1977-03-30 1979-12-18 Janssen Pharmaceutica N.V. 5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives
CA1108619A (en) * 1977-08-12 1981-09-08 Carl H. Ross 4-hydroxy-2-benzimidazolinone derivatives and the preparation thereof
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones

Also Published As

Publication number Publication date
CA1255685A (en) 1989-06-13
ES546884A0 (es) 1986-03-16
AU586187B2 (en) 1989-07-06
JPS6168473A (ja) 1986-04-08
EP0175525B1 (en) 1990-05-23
GR852189B (ja) 1986-01-10
ZA856943B (en) 1986-06-25
US4554287A (en) 1985-11-19
DE3577849D1 (de) 1990-06-28
AU4714485A (en) 1986-03-20
DK407885D0 (da) 1985-09-06
ATE53025T1 (de) 1990-06-15
PT81109B (en) 1987-07-06
ES8605491A1 (es) 1986-03-16
EP0175525A1 (en) 1986-03-26
PT81109A (en) 1985-10-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment