DK403782A - 9,10-substituerede 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-oner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler - Google Patents

9,10-substituerede 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-oner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler Download PDF

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Publication number
DK403782A
DK403782A DK403782A DK403782A DK403782A DK 403782 A DK403782 A DK 403782A DK 403782 A DK403782 A DK 403782A DK 403782 A DK403782 A DK 403782A DK 403782 A DK403782 A DK 403782A
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DK
Denmark
Prior art keywords
pyrimido
tetrahydro
ones
substituted
alkyl
Prior art date
Application number
DK403782A
Other languages
English (en)
Inventor
Bansi Lal
Alihussein Nomanbha Dohadwalla
Vijay Atmaram Aroskar
Nandkumar Keshaw Dadkar
Horst Dornauer
Julius Mascarenhas
Noel John De Souza
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK403782A publication Critical patent/DK403782A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK403782A 1981-09-10 1982-09-09 9,10-substituerede 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-oner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler DK403782A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813135831 DE3135831A1 (de) 1981-09-10 1981-09-10 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
DK403782A true DK403782A (da) 1983-03-11

Family

ID=6141286

Family Applications (1)

Application Number Title Priority Date Filing Date
DK403782A DK403782A (da) 1981-09-10 1982-09-09 9,10-substituerede 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isoquinolin-4-oner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler

Country Status (13)

Country Link
US (1) US4590197A (da)
EP (1) EP0075165B1 (da)
JP (1) JPS5857380A (da)
KR (1) KR880001281B1 (da)
AT (1) ATE23159T1 (da)
AU (1) AU8815182A (da)
CA (1) CA1216584A (da)
DE (2) DE3135831A1 (da)
DK (1) DK403782A (da)
ES (1) ES8400747A1 (da)
FI (1) FI823107L (da)
IL (1) IL66753A0 (da)
ZA (1) ZA826620B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135831A1 (de) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS5855362A (ja) * 1981-09-30 1983-04-01 凸版印刷株式会社 転写装飾板の製造方法
JPS58140356A (ja) * 1982-02-09 1983-08-20 電気化学工業株式会社 ライニング材
CA1237429A (en) * 1983-05-05 1988-05-31 Frank Kienzle Pyrimidone derivatives
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4011321A (en) * 1973-12-19 1977-03-08 Smith Kline & French Laboratories Limited Pharmaceutical compositions and methods of inhibiting β-adrenergic receptors
AR206061A1 (es) * 1974-11-15 1976-06-23 Knoll Ag Procedimiento para la produccion de nuevas 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7-, 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-isoquinolinas de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-6-metoxi-isoquinolinas y de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-7-metoxi-isoquinolinas eventualmente metiladas en la posicion 1
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
DE2719562C2 (de) * 1976-05-08 1986-05-07 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
NZ185900A (en) * 1976-12-10 1981-04-24 Hoechst Ag Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines
IN147624B (da) * 1976-12-10 1980-05-03 Hoechst Pharma
FI64370C (fi) * 1977-05-05 1983-11-10 Hoechst Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
IN149457B (da) * 1978-03-10 1981-12-12 Hoechst Pharma
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
FR2470130A2 (fr) * 1979-11-21 1981-05-29 Hoechst Ag Derives de pyrimido (6,1-a) isoquinoleine-4-one, leur procede de preparation et leur application en therapeutique
DE3135831A1 (de) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
IL66753A0 (en) 1982-12-31
DE3273979D1 (en) 1986-12-04
FI823107A0 (fi) 1982-09-08
ES515587A0 (es) 1983-11-01
EP0075165B1 (de) 1986-10-29
KR880001281B1 (ko) 1988-07-18
ES8400747A1 (es) 1983-11-01
EP0075165A1 (de) 1983-03-30
JPS5857380A (ja) 1983-04-05
ZA826620B (en) 1983-07-27
US4590197A (en) 1986-05-20
CA1216584A (en) 1987-01-13
DE3135831A1 (de) 1983-04-28
KR840001578A (ko) 1984-05-07
AU8815182A (en) 1983-03-17
ATE23159T1 (de) 1986-11-15
FI823107L (fi) 1983-03-11

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